Clinical trials: JIA
Septic Arthritis, Inflammatory Arthritis
Differentiate Children Septic and Inflammatory Arthritis by Comparative Analysis
The purpose is to found new biomarker that differentiate septic arthritis and Juvenile Idiopathic Arthritis in children. Synovial liquid and blood samples with proteomic, MiRNA searching, multiplex cytokine analysis and cellular…
- Conditions
- Septic Arthritis, Inflammatory Arthritis, Children
- Trial name
- DIANE (NCT03827759)
- Where
- 5 sites in France
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Polyarticular Course Juvenile Idiopathic Arthritis
Efficacy and Safety Dose Finding Study of Givinostat to Treat Polyarticular Course Juvenile Idiopathic Arthritis
The present study has been designed in order to evaluate the efficacy and safety of two doses of Givinostat in subjects with polyarticular course JIA Givinostat ready-to-use suspension especially intended for paediatric…
- Trial name
- NCT01261624
- Testing
- Givinostat
- Where
- 13 sites in Belgium, Czechia and 5 more
- Volunteers
- 16 people
- Sponsor
- Italfarmaco
Juvenile Idiopathic Arthritis (JIA), Crohn Disease (CD)
Study on Eating Habits and Association with "omic" Profiles in Families with a Subject Affected by a Chronic Immune-mediated Inflammatory Pathology. Observational Multicenter Study.
The proposed study is part of a PNRR 2022 project (call "Non-Communicable Chronic Diseases (NCDs) with high impact on healthcare and social assistance systems," currently awaiting funding response) and represents the continuation…
- Conditions
- Juvenile Idiopathic Arthritis (JIA), Crohn Disease (CD), Ulcerative Colitis (UC)
- Trial name
- DIETA-MICIREUM (NCT06862843)
- Testing
- Collecting questionnaires and biological samples
- Where
- 4 sites in Italy
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Meyer Children's Hospital IRCCS
Juvenile Idiopathic Arthritis, Juvenile Arthritis
Effectiveness and Feasibility of a Home-based Exercise Program for Adolescents With Juvenile Idiopathic Arthritis
This study will aim to test the effectiveness and feasibility of a technology-supported home-based exercise program in adolescents with JIA.
- Conditions
- Juvenile Idiopathic Arthritis, Juvenile Arthritis, Juvenile Rheumatoid Arthritis
- Trial name
- THE_JIA (NCT05114343)
- Testing
- Exercise
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- University of Sao Paulo General Hospital
Juvenile Idiopathic Arthritis
Assessment of Composite Inflammatory Ratios in Juvenile Idiopathic Arthritis and Their Association With Disease Activity
Juvenile Idiopathic Arthritis (JIA) is a prevalent pediatric rheumatic disorder characterized by persistent inflammation of one or more joints in children and adolescents.
- Trial name
- NCT07083466
- Testing
- complete blood count, serum albumin
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Sohag University
Juvenile Idiopathic Arthritis
Clinical Study of Genakumab for Injection in Chinese Healthy Volunteers
To evaluate the safety and tolerability of single subcutaneous injection of Genakumab for Injection in Chinese healthy adult volunteers
- Trial name
- NCT04337437
- Testing
- Genakumab
- Where
- China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Changchun GeneScience Pharmaceutical Co., Ltd.
Juvenile Idiopathic Arthritis
Efficiency of Supervised Exercise Program Versus Mobile-Based Exercise Program in Juvenile Idiopathic Arthritis
Juvenile Idiopathic Arthritis (JIA) is a heterogeneous, idiopathic, chronic inflammatory, rheumatic disease that is most common in childhood and is thought to involve immunological mechanisms in its etiopathogenesis.
- Trial name
- NCT06193681
- Testing
- Pedi@ctivity Exercise Mobile Application Exercise Program, Supervised Exercise Group
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people
- Sponsor
- Istanbul University - Cerrahpasa
Juvenile Idiopathic Arthritis
A Repeated Dose-finding Study of Sarilumab in Children and Adolescents With Systemic Juvenile Idiopathic Arthritis (SKYPS)
Primary Objective: To describe the pharmacokinetic (PK) profile of sarilumab in patients aged 1-17 years with Systemic Juvenile Idiopathic Arthritis (sJIA) in order to identify the dose and regimen for adequate treatment of this…
- Trial name
- SKYPS (NCT02991469)
- Testing
- Sarilumab SAR153191 (REGN88)
- Where
- 40 sites in Argentina, Canada and 12 more
- Volunteers
- 51 people
- Sponsor
- Sanofi
Autoimmune Rheumatologic Disease
Hepatitis A Vaccine Dosing Regimens Among Pediatric Patients on Immunosuppressive Therapy
The study is a prospective, single centre, double-blinded randomized controlled trial whose goal is to compare the immune response of a population of immunosuppressed pediatric rheumatology patients on immunosuppressive…
- Trial name
- NCT02917577
- Testing
- Avaxim Pediatric®, Avaxim ® (adult)
- Where
- Canada
- Volunteers
- 19 people
- Sponsor
- University of Calgary
Arthritis, Juvenile Rheumatoid
Special Investigation (All Case Survey) in Patients With Juvenile Idiopathic Arthritis
This study of Humira will be conducted to clarify the following with regard to the treatment of juvenile idiopathic arthritis affecting multiple joints with this drug: Unknown adverse drug reactions (especially important adverse…
- Trial name
- NCT01412021
- Volunteers
- 375 people
- Sponsor
- AbbVie
Exercise Therapy, Juvenile Idiopathic Arthritis
Effects of Telemonitoring-supported Game-based Home Exercises in Juvenile Idiopathic Arthritis
In order to cope with pain, improve quality of life and prevent kinesiophobia in children with juvenile idiopathic arthritis, most of the physiotherapy approaches used so far are standard.
- Trial name
- NCT05837247
- Testing
- Game-based telerehabilitation exercises, Home exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Istanbul University - Cerrahpasa
Heart Failure
Pharmacokinetic and Pharmacodynamic of Jia Shen Tablets in Chronic Heart Failure
Evaluate the pharmacokinetic and pharmacodynamic characteristics of Jia Shen Tablets in patients with Chronic Heart Failure.
- Trial name
- NCT06348498
- Testing
- Jia Shen Tablet
- Where
- China
- Volunteers
- 18 people
- Sponsor
- Tasly Pharmaceutical Group Co., Ltd
Systemic Vasculitis, Spondylarthropathies
Vaccination Against Herpes Zoster in Patients With Inflammatory Rheumatic Diseases
The purpose of HZ-REUMA study is explore vaccine response and protection against shingles (herpes zoster, HZ) after vaccination with two doses of Shingrix in immunosuppressed patients with inflammatory rheumatic diseases (IRD)…
- Conditions
- Systemic Vasculitis, Spondylarthropathies, Psoriatic Arthritis, Scleroderma
- Trial name
- HZ-REUMA (NCT06763783)
- Testing
- Shingrix, vaccination with 2 doses of Shingrix vaccine
- Where
- Sweden
- Volunteers
- 240 people
- Sponsor
- Region Skane
Uveitis, Juvenile Idiopathic Arthritis
Cyclosporine A in the Treatment of Juvenile Idiopathic Arthritis (JIA) Associated Chronic Anterior Uveitis
Juvenile idiopathic arthritis (JIA) is often associated with chronic anterior uveitis. Presence of vision threatening complications may indicate immunosuppressive therapy.
- Trial name
- NCT00404482
- Testing
- Cyclosporine A
- Where
- 3 sites in Germany
- Volunteers
- 60 people
- Sponsor
- St. Franziskus Hospital
Refractory Juvenile Idiopathic Arthritis (Despite 2 DMARDs Still Active)
The Efficacy of Intravenous Pulse in Attaining Remission in Refractory Juvenile Idiopathic Arthritis
Interventional phase 3 study aiming to unravel the value of pulse steroids in achieving remission or low disease activity in refractory active JIA
- Trial name
- NCT06463379
- Testing
- Solumedrol
- Where
- Egypt
- Volunteers
- 215 people
- Sponsor
- Sohag University
Arthritis, Juvenile Rheumatoid
A One Year Double-blind Trial to Investigate the Efficacy and Safety of Meloxicam Oral Suspension in Juvenile Rheumatoid Arthritis (JRA/JIA)
A one year double-blind trial to investigate the efficacy and safety of meloxicam oral suspension 0.25 mg/kg and 0.125 mg/kg administered once daily in comparison to naproxen oral suspension 5 mg/kg administered twice daily in…
- Trial name
- NCT00279747
- Testing
- meloxicam 0.25 mg/kg, meloxicam 0.125 mg/kg, naproxen 10 mg/kg
- Where
- 34 sites in Austria, Belgium and 5 more
- Volunteers
- 226 people
- Sponsor
- Boehringer Ingelheim
Polyarticular Juvenile Idiopathic Arthritis
Long-term Treatment Study of MRA for Polyarticular Juvenile Idiopathic Arthritis (pJIA)
This is an open-label, extension, Phase III study to evaluate the long-term safety, efficacy and PK of MRA in patients with pJIA who participated in Study MRA318JP.
- Trial name
- NCT00144625
- Testing
- MRA(Tocilizumab)
- Volunteers
- 19 people
- Sponsor
- Chugai Pharmaceutical
Juvenile Idiopathic Arthritis
Immersive Virtual Reality Exergaming Program in Adolescents Diagnosed With Juvenile Idiopathic Arthritis
The aim of the study is to investigate the effect of home-based exercise program versus personalized IVR exergame (Fit-XR) program on physical fitness, functional capacity and physical activity in adolescents with Juvenile…
- Trial name
- JiaFiT-XR (NCT06176846)
- Testing
- Immersive Virtual Reality Exergaming Program, Home-Based Exercise Program
- Where
- 4 sites in Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Juvenile Idiopathic Arthritis
Efficacy of Web-based Pain Self-management for Adolescents With Juvenile Idiopathic Arthritis
The purpose of this multi-site randomized clinical trial is to determine if an online coping skills training program will produce superior improvements in pain and health-related quality of life outcomes for adolescents with JIA…
- Trial name
- WebSMART (NCT01541917)
- Testing
- Web-based coping skills training, Online disease education
- Where
- 10 sites in United States
- Volunteers
- 305 people
- Sponsor
- Children's Mercy Hospital Kansas City
Juvenile Rheumatoid Arthritis
Effect of Electroacupuncture on Refractory Pain in Juvenile Rheumatoid Arthritis: Randomized Controlled Trial
the purpose of the study is to investigate the effect of Electrical Acupuncture Versus naproxen phonophoresis on Refractory pain in Juvenile Rheumatoid arthritis
- Trial name
- NCT05504382
- Testing
- naproxen phonophoresis
- Where
- Egypt
- Volunteers
- 42 people
- Sponsor
- Mohamed Abdelmoneim El Meligy