Clinical trials: JIA
Arthritis, Juvenile Rheumatoid
A Study To Evaluate The Effects Of Celecoxib (Celebrex®) Or Naproxen On Blood Pressure In Pediatric Subjects
This Is A Multicenter, Active-Controlled Trial To Evaluate The Effects Of Celecoxib (Celebrex®) Or Naproxen On Blood Pressure In Pediatric Subjects With Juvenile Idiopathic Arthritis
- Trial name
- NCT00807846
- Testing
- Celecoxib, Naproxen
- Where
- 39 sites in United States, Chile and 8 more
- Volunteers
- 201 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Active Systemic, Onset Juvenile Idiopathic Arthritis
Open Label, Multicentre Trial to Assess Safety and Efficacy of ITF2357 in Active Systemic Juvenile Idiopathic Arthritis
This study has the following objectives: Primary objective: To determine the safety and tolerability of oral ITF2357 in patients with active SOJIA with inadequate response or intolerance to standard therapy with oral steroids and…
- Trial name
- SOJIA (NCT00570661)
- Testing
- ITF2357
- Where
- 5 sites in Romania, Serbia
- Volunteers
- 17 people
- Sponsor
- Italfarmaco
Arthritis
Ultrasound Assessment of Steroid Joint Injections in Juvenile Idiopathic Arthritis
Juvenile idiopathic arthritis (JIA) is a serious autoimmune childhood disease that encompasses several types of chronic arthritis.
- Trial name
- NCT01114243
- Testing
- Ultrasound imaging
- Where
- United States
- Sponsor
- Stanford University
Juvenile Arthritis
Jointstrong Intervention for Juvenile Arthritis
This study is a randomized wait-list controlled trial with repeated measures. There will be two groups: (1) standard medical care (wait-list control), and (2) standard medical care plus the adjunctive Jointstrong pain coping…
- Trial name
- NCT01166750
- Testing
- CD-ROM, Wait-list Control Group
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- Michael Rapoff, Ph.D.
Menopausal Women
The Influence of Chinese Medicine on Metabolomics in Menopausal or Postpartum Women
Traditional Chinese herbal medicine, no matter mono-therapy or poly-pharmacy, is composed of complicated chemical constituents. Many confounding factors influence activity of Chinese herbs, including the origin of the herbs…
- Trial name
- NCT01264068
- Testing
- Finished Herbal Product such as Suan Tsao Jen Tang, Jia-Wey Shiau-Yau San
- Where
- Taiwan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Taipei City Hospital
Juvenile Idiopathic Arthritis
Cost of Care for Juvenile Idiopathic Arthritis
This project seeks to collect data on healthcare utilization and expenditure rates in Juvenile Idiopathic Arthritis (JIA) patients from across the US, correlate these costs with disease activity and outcome measures and determine…
- Trial name
- NCT01469897
- Where
- 3 sites in United States
- Volunteers
- 165 people
- Sponsor
- The Cleveland Clinic
Juvenile Idiopathic Arthritis (JIA), Childhood Rheumatic Diseases
Investigation of Catastrophizing of Pain Reported by Parents in JIA Patients
Juvenile idiopathic arthritis (JIA) is the primary rheumatic disease reported to affect the pediatric population. Research suggests that parents' thoughts and feelings about their child's pain, specifically with JIA diagnosis…
- Trial name
- NCT07185750
- Testing
- Questionnaire application for JIA cases and their parents
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Hacettepe University
Polyarticular Juvenile Idiopathic Arthritis
An Observational Study to Assess Change in Disease Activity and Adverse Events of Adalimumab in Chinese Pediatric Participants With Polyarticular Juvenile Idiopathic Arthritis (pJIA)
Juvenile idiopathic arthritis (JIA) is the most common rheumatic disease affecting children, characterized by chronic synovitis with systemic multi-organ damage.
- Trial name
- NCT05411211
- Where
- 2 sites in China
- Volunteers
- 20 people
- Sponsor
- AbbVie
Juvenile Idiopathic Arthritis
iCanCope With Pain: Usability and Feasibility Testing of a Smartphone Application to Manage Pain in Youth With Arthritis
This study will look at the use and impact of smartphone application (app) for adolescents with ongoing pain caused by their juvenile idiopathic arthritis (JIA).The current project will include three studies.
- Trial name
- NCT02764346
- Testing
- iCanCope app, iCanCope attention control app
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- The Hospital for Sick Children
Juvenile Idiopathic Arthritis
Jointly Managing JIA Online: An Internet-based Psycho-educational Game for Children With JIA and Their Parents
Arthritis in children is a long-term illness and it can make a child's life very difficult. In children 8-11 years old, the child and their family work together to deal with the problems that arthritis can cause.
- Trial name
- NCT02610166
- Testing
- Game, Usual Care
- Where
- 7 sites in Canada
- Volunteers
- 112 people
- Sponsor
- The Hospital for Sick Children
Arthritis, Juvenile, Arthritis, Childhood
Feasibility of a Diet Intervention for Juvenile Arthritis
Families of children with arthritis are highly interested in the benefits of diet to improve their child's disease and future health outcomes.
- Conditions
- Arthritis, Juvenile, Arthritis, Childhood, Juvenile Idiopathic Arthritis
- Trial name
- DIGEST-JA (NCT06474546)
- Testing
- Diet intervention
- Where
- 7 sites in Canada
- Volunteers
- 54 people
- Sponsor
- The Hospital for Sick Children
Juvenile Idiopathic Arthritis
Cellular and Molecular Adaptations to Exercise-induced Inflammatory Response in Children With Autoimmune Diseases
Juvenile idiopathic arthritis (JIA) is a chronic disease characterized by persistent joint inflammation. The immune system disruption that leads to overproduction of pro-inflammatory cytokines (TNF-α, IL-1, IL-6) is a cascade of…
- Trial name
- AJI-APA (NCT02502539)
- Testing
- Controlled physical activity
- Where
- France
- Volunteers
- 20 people
- Sponsor
- University Hospital, Clermont-Ferrand
Polyarticular Course Juvenile Idiopathic Arthritis
Safety, Tolerability, Pharmacokinetics, and Efficacy of Filgotinib for the Treatment of Polyarticular-course Juvenile Idiopathic Arthritis in Children and Adolescents
This is a multicenter Phase 3, open-label, single-arm study to evaluate the safety, tolerability, PK, and efficacy of orally administered filgotinib for up to 18 weeks.
- Trial name
- GALAHOPPER (NCT07554495)
- Testing
- Filgotinib
- Where
- 14 sites in Belgium, Czechia and 7 more
- Volunteers
- 65 people
- Sponsor
- Alfasigma S.p.A.
Rheumatic Diseases, Arthritis
Pain-Sleep in Rheumatic Disease
Overall, our understanding of how pain and sleep are experienced and how they can be treated in teenagers with rheumatic diseases is limited.
- Conditions
- Rheumatic Diseases, Arthritis, Lupus, Lupus Arthritis, Systemic Lupus Erythematosus
- Trial name
- NCT07775612
- Testing
- Better Nights, Better Days for Youth
- Volunteers
- 43 people
- Sponsor
- The Hospital for Sick Children
Juvenile Idiopathic Arthritis
Assessment of Physical Activity Among Juvenile Idiopathic Arthritis Children Performed With Actigraphy
This study aims to describe physical activity among juvenile idiopathic arthritis children, according to the disease's and patient's characteristics.
- Trial name
- AJIACT (NCT04167488)
- Testing
- Actigraphic measurement
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Juvenile Idiopathic Arthritis (JIA)
Structured vs. Exergaming-Based Core Stabilization in Children With Juvenile Idiopathic Arthritis
Juvenile Idiopathic Arthritis (JIA) is the most common inflammatory, autoimmune, and chronic rheumatic disease of childhood (1).
- Trial name
- NCT07234747
- Testing
- Structured Core Stabilization Exercise Training, Exergaming-Based Core Stabilization Training
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Istanbul University - Cerrahpasa
Juvenile Idiopathic Arthritis
Oxidation Rates of the Different Substrates During Exercise in Children and Adolescents With Juvenile Idiopathic Arthritis. Case-control Study and Cases Treated / Cases Not Treated With Anti-TNFα
During exercise, energy comes mainly from carbohydrates and lipids. The relative contribution of lipids and glucose as energy substrates to exercise depends on the parameters of the exercise (duration, intensity and level of…
- Trial name
- OSE-JIA (NCT02977416)
- Testing
- anti-TNFα
- Where
- France
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Polyarticular Course Juvenile Idiopathic Arthritis (JIA)
Trial of Sequential Medications AfteR TNFi Failure in Juvenile Idiopathic Arthritis
This study is an open-label, randomized, multicenter trial that incorporates a multi-arm design comparing each of 3 non-TNFi (Tumor Necrosis Factor inhibitor) medications to a second TNFi (active control) within a sequential…
- Trial name
- SMART-JIA (NCT06654882)
- Testing
- TNFi (Tumor Necrosis Factor inhibitor) medication, Abatacept, Tocilizumab
- Where
- 7 sites in United States, Germany and 2 more
- Volunteers
- 400 people
- Sponsor
- Duke University
Enthesitis Related Arthritis (ERA)
A Study of the Efficacy and Safety of Adalimumab in Pediatric Subjects With Enthesitis Related Arthritis
The purpose of this study is to evaluate the efficacy and safety of adalimumab given subcutaneously every other week (eow) as compared to placebo in pediatric subjects with Enthesitis Related Arthritis (ERA).
- Trial name
- NCT01166282
- Testing
- adalimumab
- Volunteers
- 46 people
- Sponsor
- AbbVie (prior sponsor, Abbott)
Juvenile Idiopathic Arthritis
An Investigation Into the Relationship Between Dietary Intake and Health-related Quality of Life in Children and Young People With Juvenile Idiopathic Arthritis
"Physical activity and diet in children and young people with arthritis" A qualitative study of exploring stake holder's experiences.
- Trial name
- JIA (NCT04903067)
- Where
- United Kingdom
- Volunteers
- 99 people
- Sponsor
- Oxford Brookes University