Clinical trials: Jaundice, Neonatal
Neonatal Jaundice, Hyperbilirubinemia
Compassionate Use of Stanate (TM) [Stannsoporfin]
The purpose of this protocol is to make Stanate (TM) [stannsoporfin, tin-mesoporphyrin] available to infants who meet the following criteria: 1.
- Trial name
- NCT00076960
- Testing
- Stanate (TM) [stannsoporfin, tin-mesoporphyrin]
- Where
- United States
- Sponsor
- InfaCare Pharmaceuticals Corporation, a Mallinckrodt Company
Hyperbilirubinemia
Transcutaneous Bilirubinometry in Healthy Term and Near-Term Neonates
Objectives: Bilirubin measured by transcutaneous bilirubinometry (TcB) is a reasonably accurate estimate of serum total bilirubin (STB).
- Trial name
- NCT00653874
- Testing
- BiliChek (jaundice assessment), Transcutaneous bilirubinometry (TcB), Clinical asessment of bilirubin (CaB)
- Where
- India
- Volunteers
- 617 people
- Sponsor
- All India Institute of Medical Sciences
Neonatal Jaundice, Neonatal Hyperbilirubinemia
Evaluation of Bilirubin Estimates in Newborns From Smartphone Digital Images in a Population in Botswana
This project aims to test a novel smartphone application, Picterus, which provides a cheaper, patient-friendly, and more readily means of neonatal jaundice detection.
- Trial name
- BILIAPPBOT (NCT06399146)
- Testing
- Picterus App
- Where
- Botswana
- Volunteers
- 150 people
- Sponsor
- Hillerod Hospital, Denmark
Neonatal Jaundice
Comparison of the Efficacy of Phototherapy Using Blue LED's With Wavelength 478 vs. 459 nm.
Treatment of neonatal jaundice is phototherapy with blue light at wavelength about 460 nm and irradiance > 30 uw/cm2/nm. Though, recent in vitro models have suggested that a wavelength of 478 nm should be optimal in reducing…
- Trial name
- NCT03183986
- Testing
- Phototherapy
- Where
- Denmark
- Volunteers
- 100 people
- Sponsor
- University of Aarhus
Neonatal Jaundice From Other Specified Causes, ABO Incompatibility
The Role of Breastmilk and Serum Exosomes in Neonatal Jaundice Due to ABO Incompatibility
Neonatal jaundice is a major global health issue that can lead to serious complications and even death if not promptly treated. ABO incompatibility is a common cause of pathological neonatal jaundice, but there are currently no…
- Conditions
- Neonatal Jaundice From Other Specified Causes, ABO Incompatibility, ABO Hemolytic Disease
- Trial name
- NCT06502847
- Testing
- Exosome profile study
- Where
- Turkey (Türkiye)
- Volunteers
- 338 people
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Jaundice, Neonatal, Hyperbilirubinemia, Neonatal
Identification of Jaundice in Newborns Using Smartphones
Neonatal jaundice is a common and most often harmless condition. However, when unrecognized it can be fatal or cause serious brain injury. Three quarters of these deaths are estimated to occur in the poorest regions of the world.
- Trial name
- NCT04182555
- Testing
- Bilirubin estimates from Smartphone Application, Bilirubin concentration measured in standard blood samples, Bilirubin estimates from standard transcutaneous device
- Where
- 2 sites in Norway
- Volunteers
- 220 people
- Sponsor
- St. Olavs Hospital
Jaundice, Neonatal
Treatment of Neonatal Jaundice With Filtered Sunlight Phototherapy: Safety and Efficacy in African Neonates
The primary objective of this study is to determine the safety and efficacy of filtered sunlight phototherapy. Sunlight will be filtered by flexible (window-tinting) film.
- Trial name
- NCT01434810
- Testing
- Filtered-sunlight phototherapy, Conventional phototherapy
- Where
- Nigeria
- Volunteers
- 447 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Jaundice, Neonatal, Phototherapy
Effectiveness, Safety and Perceptions With the Use of One LED Blanket Device in the Ambulatory Treatment of Jaundice
Objective: to evaluate the effectiveness, safety and level of satisfaction of parents and healthcare team with one innovative device for phototherapy to which a LED light mesh has been incorporated(a blanket), comparing it with…
- Trial name
- LEDlightT2 (NCT03569254)
- Testing
- Neomedlight Phototherapy Blanket, Ohmeda-Fiber Optic Phototherapy Blanket
- Where
- Colombia
- Volunteers
- 64 people
- Sponsor
- Nathalie Charpak
Nutritional and Metabolic Diseases
Efficacy and Safety of Stannsoporfin in Neonates
This is a multi-center, randomized, sham injection-controlled (placebo) masked trial of a single intramuscular injection of Stannsoporfin compared to "sham" (placebo) in healthy term and near-term newborns admitted to the…
- Trial name
- NCT02685137
- Testing
- stannsoporfin
- Where
- United States
- Volunteers
- 185 people
- Sponsor
- InfaCare Pharmaceuticals Corporation, a Mallinckrodt Company
Neonatal Jaundice
NeoSCB App for Screening Jaundice in Newborns
About 60% of babies born after 36 weeks of pregnancy have jaundice during the first two weeks of life. Due to the accumulation of bilirubin in the bloodstream, jaundiced babies appear yellow, which allows healthcare professionals…
- Trial name
- neoSCB (NCT06963450)
- Testing
- Taking photos of a baby's eye
- Where
- United Kingdom
- Volunteers
- 405 people, healthy volunteers welcome
- Sponsor
- University College, London
Neonatal Jaundice, Hyperbilirubinemia
Transcutaneous Screening for Risk of Severe Hyperbilirubinemia in South African Newborns
In South Africa, healthy term newborns are usually discharged early (<72 hours after delivery). Many studies have shown that hospital readmission rates have increased with this practice, and jaundice or hyperbilirubinemia is the…
- Trial name
- NCT02613676
- Testing
- Transcutaneous bilirubin screening, Standard care (Visual inspection)
- Where
- South Africa
- Volunteers
- 1,858 people, healthy volunteers welcome
- Sponsor
- University of Stellenbosch
Jaundice, Neonatal
Comparison Of Fenofibrate Vs Phenobarbitone As Adjunct To Phototherapy In Reducing Total Serum Bilirubin In Indirect Hyperbilirubinemia In Neonates
This is a prospective, randomized, open-label controlled trial comparing fenofibrate (10 mg/kg) and phenobarbitone (3 mg/kg) as adjuncts to conventional phototherapy in neonates with unconjugated hyperbilirubinemia.
- Trial name
- NCT07774741
- Testing
- Fenofibrate + Phototherapy, Phenobarbitone + Phototherapy
- Volunteers
- 70 people
- Sponsor
- Rubab Fatima
Hyperbilirubinemia
Light-emitting Diodes (LED) Phototherapy for Hyperbilirubinemia of Term Newborn
Phototherapy is almost (beside exchange transfusion) the unique treatment for hyperbilirubinemia of the newborn. Its efficacy to decrease bilirubin level (because the light interacts with bilirubin at the skin level to transform…
- Trial name
- DELF (NCT01136577)
- Testing
- Phototherapy
- Where
- France
- Volunteers
- 44 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Jaundice, Neonatal
The Effectiveness of Probiotics in Neonatal Jaundice
Hyperbilirubinemia is a prevalent problem in babies that necessitates medical attention. Probiotic administration as adjuvant therapy may have a positive impact on the pathological neonatal unconjugated hyperbilirubinemia.
- Trial name
- NCT06449508
- Testing
- Probiotic Formula
- Volunteers
- 44 people
- Sponsor
- Tanta University
Jaundice, Neonatal
Transcutaneous Bilirubin Measurements in Neonates Post Phototherapy
Can transcutaneous bilirubin (TcB) measurements be utilised to assess rebound hyperbilirubinaemia following phototherapy in neonates?
- Trial name
- NCT04719104
- Testing
- Transcutaneous Bilirubin Meter - 'Bilimeter'
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- NHS Greater Glasgow and Clyde
Jaundice, Jaundice, Neonatal
Development of a Neonatal Jaundice Treatment Accelerator by Redirection of Unused Light During Phototherapy
This is a descriptive prospective study of safety and efficacy of the reflective PT ring device. Neonates with an elevated total serum bilirubin (TSB) meeting PT criteria per their clinician during hospital admission will be…
- Trial name
- NCT04021927
- Testing
- Ring Phototherapy
- Where
- United States
- Sponsor
- University of Minnesota
Hyperbilirubinemia, Neonatal
Intelligent Follow-up of Neonatal Jaundice Based on Early Indicators and Internet Communications
In this prospective multi-center randomized clinical trial, a new follow-up strategy for neonatal jaundice after discharge will be evaluated.
- Trial name
- NCT05365984
- Testing
- end tidal carbon monoxide corrected for ambient carbon monoxide （ETCOc）, Internet Plus technology
- Volunteers
- 2,500 people
- Sponsor
- Women's Hospital School Of Medicine Zhejiang University
Jaundice, Neonatal
A mHealth Application as a Screening Tool for Neonatal Jaundice in Filipino Neonates
The purpose of the study is to test the reliability of the Picterus smartphone application in Filipino neonates. A descriptive cross-sectional study will be the method to understand the correlation of the modalities and to…
- Trial name
- NCT05616845
- Testing
- Picterus Jaundice Pro
- Where
- Philippines
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Picterus AS
Neonatal Jaundice
Comparing the Effect of Vimala Massage Versus Hydrotherapy on the Clinical Outcomes of Neonatal Hyperbilirubinemia
The aim of this study is to evaluate the effect of Vimala massage versus hydrotherapy on the clinical outcomes of neonatal hyperbilirubinemia.
- Trial name
- NCT06595368
- Testing
- Vimala massage, Hydrotherapy
- Where
- Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Kafrelsheikh University
End Tidal Carbon Monoxide Excretion as a Diagnostic Tool for Hemolysis in the Newborn, Neonatal Jaundice
End Tidal Carbon Monoxide (ETCO): - A Tool to Aid Identification of Neonatal Hemolysis
The purpose of this study is to evaluate if adding a noninvasive testing of End Tidal Carbon Monoxide with a FDA approved device will help improve management of jaundice in the Neonates by reducing the number of lab draws, Coombs…
- Conditions
- End Tidal Carbon Monoxide Excretion as a Diagnostic Tool for Hemolysis in the Newborn, Neonatal Jaundice, End Tidal Carbon Monoxide
- Trial name
- NCT05475223
- Testing
- End Tidal Carbon Monoxide Value
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Cedars-Sinai Medical Center