Clinical trials: Jaw Diseases / Diagnosis
Partially Edentulous Jaw
Study on OsseoSpeed™ TX Implants in a Chinese Population
To investigate the clinical efficacy of OsseoSpeed™ TX implants in a Chinese population by evaluation of marginal bone level alteration, implant stability and implant survival in the posterior mandible up to 3 years after…
- Trial name
- NCT01346683
- Testing
- OsseoSpeed TX
- Where
- 3 sites in China
- Volunteers
- 45 people
- Sponsor
- Dentsply Sirona Implants and Consumables
Temporomandibular Joint Disorders, Facial Pain
Device for Alleviating Temporomandibular Joint (TMJ) Pain
The goal of this clinical trial is to evaluate the safety and effectiveness of the investigational BTL-043 device in alleviating Temporomandibular Joint (TMJ) pain in adults aged 22 years and older.
- Conditions
- Temporomandibular Joint Disorders, Facial Pain, Temporomandibular Joint Dysfunction Syndrome
- Trial name
- NCT07624539
- Testing
- Treatment with BTL-043
- Where
- 3 sites in United States
- Volunteers
- 31 people
- Sponsor
- BTL Industries Ltd.
Jaw, Edentulous, Jaw, Edentulous, Partially
Prospective Neodent® Zirconia System Study
The Neodent® Zirconia Implant is designed for the treatment of oral endosteal implantation for the functional and aesthetic rehabilitation, allowing for treatment of patients with different bone qualities.
- Trial name
- NCT04545840
- Testing
- Dental Implants
- Where
- Brazil
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Neodent
Jaw, Edentulous, Partially
Clinical Study Comparing Submerged Versus Trans-mucosal Healing of P.004 Implants in the Anterior Mandible and Maxilla
The purpose of this study is To demonstrate that there is no difference in change in bone level around P.004 implants between 1st stage surgery and 6 months post surgery when transmucosal implant placement is compared to…
- Trial name
- NCT00906425
- Testing
- Straumann Bone Level Implant
- Where
- 11 sites in United States, Australia and 5 more
- Volunteers
- 145 people
- Sponsor
- Institut Straumann AG
Zygomatic Fractures, Orbital Fractures
Stryker Universal Midface and Upper-Face Fixation System: A Retrospective Post Market Follow Up
A retrospective post-market clinical follow-up to confirm the performance and safety of the Upper-Face and Mid-Face modules of the Stryker Universal CMF System in a clinical setting.
- Conditions
- Zygomatic Fractures, Orbital Fractures, Maxilla Fractures, Facial Fractures
- Trial name
- UMF (NCT07245719)
- Testing
- Upper-Face and/or Mid-Face modules (1.2 / 1.7 modules) of the Stryker Universal CMF System
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Stryker Craniomaxillofacial
PTCH1 or SMO Activated Solid and Hematologic Tumors
LDE225 for Patients With PTCH1 or SMO Mutated Tumors
The purpose of this signal seeking study is to determine whether treatment with LDE225 demonstrates sufficient efficacy in hedgehog pathway-mutated solid tumors and/or hematologic malignancies to warrant further study
- Trial name
- SIGNATURE (NCT02002689)
- Testing
- LDE225
- Where
- 10 sites in United States
- Volunteers
- 10 people
- Sponsor
- Novartis Pharmaceuticals
Jaw, Edentulous, Partially
A Clinical Study on Acuris™ - Conometric Concept for Single Tooth Restoration
The purpose of this study is to evaluate the outcome of prosthetic survival of the Acuris conometric concept 1 year after permanent restoration, since this is a new mode of retention using friction for seating the crown of single…
- Trial name
- NCT04063878
- Testing
- Conometric Abutment and Conometric Final Cap
- Where
- 9 sites in United States, Canada and 4 more
- Volunteers
- 160 people
- Sponsor
- Dentsply Sirona Implants and Consumables
Partially Edentulous Jaw
Study on OsseoSpeed™ TX Narrow Implants in the Upper Jaw in a Chinese Population
The purpose of this study is to investigate the clinical efficacy of OsseoSpeed™ TX 3mm diameter implant in a Chinese population by evaluation of marginal bone level alteration, implant stability and implant survival in the…
- Trial name
- NCT01389258
- Testing
- OsseoSpeed™ TX
- Where
- 3 sites in China
- Volunteers
- 45 people
- Sponsor
- Dentsply Sirona Implants and Consumables
Temporomandibular Disorder, Headache
A Clinical Trial of the Optimal Treatment Period and Long-term Efficacy of Functional Electrical Stimulation (FES) on Sleep Bruxism
To investigate the effect of the treatment with Grindcare® on the parafunction of the muscles- and jaw activity (Bruxism) during sleep.
- Trial name
- NCT01000389
- Testing
- Grindcare® (Biofeedback)
- Where
- Denmark
- Volunteers
- 23 people
- Sponsor
- Medotech A/S
Edentulous Jaw
T3 Certain Tapered With DCD vs T3 Certain Tapered Non-DCD
This will be a prospective, randomized multicenter study to determine the safety and efficacy of the T3 Certain Tapered with DCD as compared to T3 Certain Tapered without DCD.
- Trial name
- Apple (NCT04354688)
- Testing
- T3 Certain Tapered Implant
- Where
- 2 sites in Chile, Greece
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- ZimVie
Basal Cell Carcinoma, Gorlin Syndrome
Efficacy, Safety and Pharmacokinetics of Oral LDE225 in Treatment of Patients With Nevoid Basal Cell Carcinoma Syndrome (NBCCS)
This was a phase II, double-blind, randomized, proof-of-concept, dose-ranging trial evaluating the efficacy, safety and pharmacokinetics of oral LDE225 in treatment of adult patients with NBCCS.
- Conditions
- Basal Cell Carcinoma, Gorlin Syndrome, Nevoid Basal Cell Carcinoma Syndrome
- Trial name
- NCT01350115
- Testing
- LDE225
- Where
- 6 sites in Austria, Belgium and 2 more
- Volunteers
- 10 people
- Sponsor
- Novartis Pharmaceuticals
Jaw, Edentulous, Partially
Implant Retained Rehabilitation With Surgical and Prosthetic Digital Workflow
The aim of this study is to prospectively collect clinical data to confirm the safety and clinical performance of Neodent Titanium Base Abutment and Pro PEEK Abutment in daily dental practice setting, by means of a randomized…
- Trial name
- NCT04066309
- Testing
- Neodent GM Helix Implant, GM Customizable Healing Abutment, GM Pro PEEK Abutment
- Where
- Brazil
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Neodent
Mandible Tumor, Mandibular Injuries
Evaluation of EpiBone-CMF for Mandibular Ramus Reconstruction
EpiBone-Craniomaxillofacial (EB-CMF) is an autologous, anatomically shaped bone graft created specifically for the patient's defect, using the patients own adipose-derived mesenchymal stem cells.
- Conditions
- Mandible Tumor, Mandibular Injuries, Mandible; Deformity
- Trial name
- EB-CMF (NCT03678467)
- Testing
- EB-CMF
- Where
- 3 sites in United States
- Volunteers
- 6 people
- Sponsor
- Epibone, Inc.
Temporomandibular Joint Disorders, TMD
Efficacy and Safety of HA35 Gel Nighttime Occlusive Application for TMD Pain
This is a prospective, single-arm, open-label, pilot clinical study to evaluate the efficacy and safety of nighttime occlusive application of 10% high-concentration 35 kDa hyaluronan (HA35) gel in subjects with temporomandibular…
- Conditions
- Temporomandibular Joint Disorders, TMD, Temporomandibular Joint Pain, Jaw Muscle Over-Tension
- Trial name
- HA35-TMJ (NCT07584642)
- Testing
- 10% High-Concentration 35 kDa Hyaluronan (HA35) Topical Gel
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Nakhia Impex LLC
Jaw, Edentulous
Multicenter Study to Evaluate the Clinical Outcome of the OmniTaper EV Implant in Single Tooth Restorations
This clinical study, funded by the company Dentsply Sirona, is being carried out to see if the newly developed tooth implant "OmniTaper EV" is safe, effective and functions as intended when replacing a lost or removed tooth.
- Trial name
- NCT05355792
- Testing
- OmniTaper EV implants
- Where
- 6 sites in Germany, Switzerland and 1 more
- Volunteers
- 139 people
- Sponsor
- Dentsply Sirona Implants and Consumables
Temporomandibular Disorder, Motor Imagery
Assessing Motor Imagery Ability of Tongue and Mouth in Subjects With and With no Temporomandibular Disorders
Temporomandibular disorder (TMD) is the symptomatic expression of a muscular or an articular impairment at the manducatory tract. TMD affects between 30 to 65% of the population with a higher prevalence for young women.
- Trial name
- TMIQ (NCT04102306)
- Testing
- reliability and validity construct of the TMIQ
- Where
- France
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Cabinet de Kinesitherapie SCM Saint-Alexandre
Temporomandibular Disorder (TMD), Temporomandibular Joint Pain
EMVITAL + EMFACE Combination Therapy for Temporomandibular Joint (TMJ) Pain Relief
This prospective, multi-center, open-label, single-arm clinical study will evaluate the efficacy and performance of the BTL-043 and BTL-785F devices for alleviating TMJ pain.
- Conditions
- Temporomandibular Disorder (TMD), Temporomandibular Joint Pain, Facial Pain, Neck Pain
- Trial name
- NCT07661121
- Testing
- Treatment with BTL-043 and BTL-785F
- Where
- 4 sites in United States
- Volunteers
- 48 people
- Sponsor
- BTL Industries Ltd.
Mandibular Fractures, Facial Fracture
Stryker Facial iD Universal Plate Configurator: A Retrospective Post Market Follow Up
A retrospective post market follow up to confirm safety and performance of Stryker's Facial iD Universal Plate Configurator (UPC) implants in the clinical setting.
- Conditions
- Mandibular Fractures, Facial Fracture, Maxilla Fracture, Orthognathic Surgical Procedures
- Trial name
- UPC (NCT07245810)
- Testing
- Orthognatic surgery, Reconstructive maxillofacial surgery, Mandible and maxillofacial trauma surgery
- Where
- 2 sites in United States
- Volunteers
- 726 people
- Sponsor
- Stryker Craniomaxillofacial
Edentulous Jaw
Mandibular Full-arch Rehabilitation With Internal Hexagonal and Conical Connection Implants
Nuvo Tapered IF (internal hexagonal connection) and CF (conical connextion) Implants were designed for the the oral functional rehabilitation using dental implants, allowing for treatment of patients with different bone…
- Trial name
- NCT05082038
- Testing
- Mandibular partial rehabilitation with IF Tapared implants, Mandibular partial rehabilitation with CF Tapared implants
- Where
- Brazil
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Neodent
Basal Cell Nevus Syndrome
Extension Study of Patidegib Topical Gel, 2% in Subjects With Gorlin Syndrome (Basal Cell Nevus Syndrome)
This is a multicenter, open label extension study evaluating the safety of Patidegib Topical Gel, 2%, applied topically twice daily to the face of adult subjects with Gorlin syndrome.
- Trial name
- NCT04308395
- Testing
- Patidegib Topical Gel, 2%
- Where
- 37 sites in United States, Belgium and 7 more
- Volunteers
- 108 people
- Sponsor
- Sol-Gel Technologies, Ltd.