Clinical trials: Jaw Relationship
Medically Related Osteonecrosis of the Jaws
Impact of Topical Pentoxifylline and Tocopherol in Treatment and Prevention of Medically-related Osteonecrosis of the Jaws
While there is no doubt about the benefits of antiresorptives, it is known that patients using these drugs are at increased risk of developing osteonecrosis of the jaws (MRNOJ), especially after oral procedures such as tooth…
- Trial name
- NCT06409546
- Testing
- Tocopherol and pentoxifilline topical gel
- Where
- Italy
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of Catania
Temporomandibular Disorders, Orofacial Pain
Genetic Polymorphisms and Their Association With Temporomandibular Disorders
Temporomandibular disorders (TMD) are the most common orofacial pain disorders of non-dental origin with the prevalence of 6.1-10.2%, and incidence of 3.9%.
- Trial name
- GenPolTMD (NCT04694274)
- Testing
- stabilization splint, physical therapy
- Where
- Croatia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Croatian Science Foundation
Osteonecrosis of the Jaw, Bisphosphonate Induced, Osteonecrosis of the Jaw, Bisphosphonate Related
Initial Management of MRONJ Stages I and II, a Clinical Trial With Detection of Salivary Biomarkers
Medication-related osteonecrosis of the jaw (MRONJ) is a serious complication in patients receiving antiresorptive therapies, such as Bisphosphonates and Denosumab.
- Trial name
- NCT04584840
- Testing
- Surgical treatment
- Where
- Spain
- Volunteers
- 50 people
- Sponsor
- Fundació d'investigació Sanitària de les Illes Balears
Bone Loss, Jaw, Edentulous
Effectiveness of 3D-printed Patient-specific Resorbable Scaffolds for Maxillary Bone Regeneration
The objective of this study is to test the bone formation capacity of a 3D printed scaffold with a plastic material called Polycaprolactone (PCL), compared to the use of synthetic bone grafts, for bone formation in the maxilla or…
- Conditions
- Bone Loss, Jaw, Edentulous, Edentulous Mouth, Jaw Fractures
- Trial name
- OSTEOPRINT (NCT06773923)
- Testing
- PCL Scaffold, PTFE + Bio-Oss®
- Where
- Chile
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Universidad Austral de Chile
Temporomandibular Joint Disc Displacement
The Efficiency of Anterior Repositioning Splint for the Management of Temporomandibular Joint Dysunction
Intra-articular temporomandibular disorders are often related to pain in the area of temporomandibular joint, ear and temple. The aim of the study was to investigate the efficiency of anterior repositioning splints for the…
- Trial name
- NCT03057262
- Testing
- Repositioning splint
- Volunteers
- 112 people
- Sponsor
- Jagiellonian University
Apical Periodontitis, Healhty
Inflammation-Related Endothelial Barrier Dysfunction in Patients With Apical Periodontitis
Inflammation is a common factor in chronic periodontitis and systemic diseases. However, to date, there is no scientific evidence supporting a causal effect of inflammation caused by apical periodontitis on endothelial barrier…
- Trial name
- NCT07292363
- Testing
- Apical lesions cure
- Where
- 2 sites in Italy
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Turin, Italy
Impression Technic, Dental, Jaw Relationship
Fabrication and Insertion of Michigan Splints by Dental Students
The aim of this study is to investigate the potential effects of different jaw relation determination (KRB) techniques on the fabrication of Michigan splints, in particular by comparing conventional methods with a wax plate and…
- Conditions
- Impression Technic, Dental, Jaw Relationship, Bruxism
- Trial name
- NCT06377475
- Testing
- Jaw relation, Questionnaire
- Where
- Switzerland
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- Juliana Marotti Großhausen
Maxillary Deficiency, Head and Neck Neoplasms
Predictors of Patient-Reported Outcomes for Maxillectomy Patients
The success of digitally fabricated obturator rehabilitation is determined not only by the prosthesis itself but also by the interaction between patient characteristics, oncologic history, prosthetic support, and…
- Trial name
- NCT07864974
- Testing
- Digitally Fabricated Obturator Prosthesis
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people
- Sponsor
- Dr. Merve Benli
Neck Pain, Temporomandibular Disorder
Evaluation of the Relationship Between Neck Pain and Temporomandibular Disorders in Office Workers
The current study aimed to explore the associations between neck pain and temporomandibular disorders in office workers
- Trial name
- NCT04900870
- Where
- Turkey (Türkiye)
- Volunteers
- 500 people
- Sponsor
- Tugba Sahbaz
Temporomandibular Disorders, Pain
Nasal Carbon Dioxide (CO2)for the Treatment of Temporomandibular Disorders (TMD)Related Pain
This purpose of this study is to evaluate the safety and efficacy of treatment with nasal CO2 in the treatment of pain and other symptoms related to temporomandibular disorder (TMD).
- Conditions
- Temporomandibular Disorders, Pain, Headaches
- Trial name
- NCT00484029
- Testing
- Nasal Carbon Dioxide, Air
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Capnia, Inc.
Temporomandibular Joint Dysfunction Syndrome
Quality of Life in Temporomandibular Joint Dysfunction
It is planned to examine the relationship between quality of life in patients with temporomandibular joint dysfunction and the patient's individual, physical and psychosocial characteristics.
- Trial name
- NCT05802953
- Testing
- Physical assessments, Questionnaire
- Where
- Turkey (Türkiye)
- Volunteers
- 67 people
- Sponsor
- Afyonkarahisar Health Sciences University
MEDICATION RELATED OSTEONECROSIS OF THE JAW
OZONE_EXO: Comparative Analysis of Protocols for Dental Exactions in Patients at Risk of MRONJ: Case-control Study
Medication-related osteonecrosis of the jaw (MRONJ) is a serious adverse reaction of antiresorptive and antiangiogenic agents; it is also a potentially painful and debilitating condition.
- Trial name
- OZONE_EXO (NCT06072404)
- Testing
- OxigenOzone_Insufflation
- Where
- Italy
- Volunteers
- 117 people, healthy volunteers welcome
- Sponsor
- University of Palermo
Medication-related Osteonecrosis of the Jaw (MRONJ)
The PENTO Protocol in Medication-related Osteonecrosis of the Jaw
Medication-related osteonecrosis of the jaw (MRONJ) occurs after taking bisphosphonates or targeted therapies. It leads to a significant decrease in quality of life with pain, eating and chewing disorders, and malnutrition.
- Trial name
- PENTO (NCT05795647)
- Testing
- Pentoxifylline+Tocopherol
- Where
- France
- Volunteers
- 17 people
- Sponsor
- University Hospital, Limoges
Medication-Related Osteonecrosis of Jaw
Therapeutic Exposures and Risk Factors in MRONJ
This study focuses on patients who have developed a condition called medication-related osteonecrosis of the jaw (MRONJ), which can occur after using certain medications.
- Trial name
- NCT06430762
- Where
- Turkey (Türkiye)
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Marmara University
Osteonecrosis Due to Drugs, Jaw, Osteonecrosis of the Jaw, Bisphosphonate Related
Medical and Surgical Treatment of MRONJ (Medication-related Osteonecrosis of the Jaw Bones)
MRONJ is an acronym used to describe medication-related osteonecrosis of the jaw bones. It has been reported by the AAOMS that bisphosphonates or denosumab can cause this condition.
- Conditions
- Osteonecrosis Due to Drugs, Jaw, Osteonecrosis of the Jaw, Bisphosphonate Related, Osteonecrosis of the Jaw, Bisphosphonate Induced
- Trial name
- NCT06917846
- Where
- Turkey (Türkiye)
- Volunteers
- 102 people
- Sponsor
- Akdeniz University
Tinnitus, Temporomandibular Joint Disorders
CBCT and Audiological Analysis of the TMJ-Tinnitus Relationship
The aim of this study is to investigate the relationship between Temporomandibular Disorders (TMD) and subjective tinnitus at both morphological and functional levels.
- Conditions
- Tinnitus, Temporomandibular Joint Disorders, Somatosensory Tinnitus, Osteoarthritis, Temporomandibular Joint
- Trial name
- NCT07460193
- Testing
- Cone Beam Computed Tomography (CBCT), Audiological Assessment, Clinical TMJ Examination
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Kutahya Health Sciences University
Tooth Wear, Occlusal Wear of Teeth
Evaluation of Temporomandibular Disorders and Their Association With Tooth Wear Using Digital Methods
Temporomandibular disorders (TMDs) are considered complex conditions in dental practice due to their multifactorial etiology. Over the years, various diagnostic methods have been introduced; however, the most widely accepted…
- Conditions
- Tooth Wear, Occlusal Wear of Teeth, Occlusal Analysis, TMJ
- Trial name
- NCT07081204
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Konya Necmettin Erbakan Üniversitesi
Medication Related Osteonecrosis of the Jaw
Use of Platelet-Rich Fibrin (PRF) in the Management of Medication-Related Osteonecrosis of the Jaw (MRONJ)
Medication-Related Osteonecrosis of the Jaw (MRONJ) is a severe and increasingly prevalent clinical condition, defined as the presence of exposed mandibular or maxillary bone in the oral cavity persisting for at least eight…
- Trial name
- NCT07464678
- Testing
- Surgical Application of Platelet-Rich Fibrin (PRF)
- Where
- Poland
- Volunteers
- 22 people
- Sponsor
- Poznan University of Medical Sciences
Stabilization of a Full Lower Denture, Edentulism in Lower Jaw
Clinical Evaluation of the Mandibular Mini-Implant Overdenture
Stabilization of existing full lower dentures by means of mini-dental implants (MDI). To test whether 4 mini-implants placed at the front of the lower jaw can stabilize an immediately-modified existing lower denture.
- Conditions
- Stabilization of a Full Lower Denture, Edentulism in Lower Jaw, Lower Denture Made Within Last Few Years
- Trial name
- NCT01064843
- Testing
- Imtec MDI
- Where
- Canada
- Volunteers
- 80 people
- Sponsor
- Solventum US LLC
Bipolar Disorders, Oral Health
Oral and Jaw Health in Bipolar Patients
The assessment of oral health, jaw health and related problems in bipolar patients is important to provide a holistic approach to patients in terms of physical, mental and psychosocial aspects and to improve quality of life.
- Trial name
- NCT06034769
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Bandırma Onyedi Eylül University