Clinical trials: Joint Contractures
Cerebral Palsy, Muscle Contracture
The Muscle in Cerebral Palsy; Sarcomere Length in Vivo and Microscopic Characterization of Biopsies.
Cerebral palsy (CP) is a motor impairment due to a brain malformation or a brain lesion before the age of two. Spasticity, hypertonus in flexor muscles, dyscoordination and an impaired sensorimotor control are cardinal symptoms.
- Conditions
- Cerebral Palsy, Muscle Contracture, Spasticity, Muscle
- Trial name
- CPMuscleSL (NCT05518565)
- Testing
- No intervention
- Where
- 3 sites in Sweden
- Volunteers
- 150 people
- Sponsor
- Eva Ponten
Dupuytren Contracture
Trial Comparing Treatment Strategies in Dupuytren's Contracture
Trial is a prospective, randomized, controlled, outcome assessor-blinded, three armed parallel 1:1:1, multicenter trial. The research objective is to determine, which treatment strategy 1) primary percutaneous needle fasciotomy…
- Trial name
- DETECT (NCT03192020)
- Testing
- Percutaneous needle fasciotomy (PNF), Collagenase Clostridium Histolyticum (CCH) 2.9 MG/ML [Xiaflex], Limited fasciectomy (LF)
- Where
- 6 sites in Finland
- Volunteers
- 302 people
- Sponsor
- Tampere University
Brachial Plexus Birth Palsy, Erbs Palsy
Pilot Test of Caregiver Training Protocol for Brachial Plexus Birth Injury
The brachial plexus is a network of nerves that exit the spinal cord from the C5-T1 nerve roots and provide all motor and sensory function to the arm from the shoulder to the fingers.
- Trial name
- CTP-BPBI (NCT06623357)
- Testing
- Pilot Training Protocol, Standard Training Protocol
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- Hugo W. Moser Research Institute at Kennedy Krieger, Inc.
Internal Rotation Contracture-shoulder, Articulation Disorders
Internal Rotation Deficit of the Glenohumeral Joint in Advanced-level Handball Players
The main objective of this study is to estimate the incidence and prevalence of Internal Rotation Deficit (IRD) defined by a measure of IRD 2 (Internal Rotation Deficit in position 2) strictly greater than 20 ° in a population of…
- Conditions
- Internal Rotation Contracture-shoulder, Articulation Disorders, Athletic Injuries
- Trial name
- GIRDH (NCT02011243)
- Where
- France
- Volunteers
- 86 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Contracture, Hand
Effects of Paraffin Wax Therapy vs METs in Post Burn Hand Contractures
The degree of the burn and the rate of scar development during healing are the main determinants of loss of hand function following thermal injury.
- Trial name
- NCT06198062
- Testing
- Paraffin wax bath therapy, Paraffin Wax Bath Therapy and Muscle Energy Techniques
- Where
- Pakistan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Contracture Joint
Determining the Reliability and Validity of a New Method for Measuring Upper Extremity Joint Range of Motion in Burn Patients Using a Tracking System
In burn patients, joint contracture is a common complication caused by hypertrophic scars, necessitating accurate evaluation and diagnosis of the degree of disability and functional deterioration.
- Trial name
- NCT05881876
- Volunteers
- 50 people
- Sponsor
- Hangang Sacred Heart Hospital
Contracture
Collagenase Injection for Contracture Management
The overall goal is to investigate the effectiveness of a novel intervention - Collagenase injection, for contracture management in patients with neurological impairments, such as stroke, brain injury, and spinal cord injury.
- Trial name
- NCT07693556
- Testing
- Active XIAFLEX Collagenase injection
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- The University of Texas Health Science Center, Houston
Contractures Resulting From Burn Scar Tissue
Joint Range of Motion in Burn Scars
The purpose of this study is to determine the relationship between cutaneous functional unit(CFU)recruitment throughout the available active range of motion of a prescribed joint in normal subjects and patients with burn scars.
- Trial name
- NCT01034813
- Where
- United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- United States Army Institute of Surgical Research
Skin Laxity, Muscle Contracture
Evaluation of the Immediate Effect and Safety of DMA™ Novel Muscle Stimulation Technology
A total of at least 15 and up to 17 healthy subjects at a single site, aged 25-45 years old, who wish to receive a lifting effect and improved muscle definition, will be included in the study.
- Trial name
- NCT04296201
- Testing
- DMA treatment
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Lumenis Be Ltd.
Myofascial Pain Syndrome, Trigger Point Pain, Myofascial
Extracorporeal Shockwave Therapy vs Mesotherapy in the Treatment of Myofascial Pain Syndrome: a Case-control Study
Myofascial Pain Syndrome (MPS) is a disorder of the musculoskeletal system manifested by referred pain associated with functional limitation, muscle contractures, and possible neuralgic manifestations; this condition is…
- Trial name
- NCT06246591
- Testing
- Extracorporeal Shockwave Therapy (Group A), Mesotherapy (Group B)
- Where
- Italy
- Volunteers
- 54 people
- Sponsor
- University of Palermo
Dupuytren's Disease
Longterm Observational Study in Subjects Treated With AA4500 in AUX-CC-854, 856, 857, 858 & 859
The purpose of study AUX-CC-860 is to assess the durability of response of the AA4500 treatment regimen. This study will also evaluate long-term safety and progression of disease in joints.
- Trial name
- NCT00954746
- Where
- 39 sites in United States, Australia and 4 more
- Volunteers
- 645 people
- Sponsor
- Endo USA Inc., a Keenova Therapeutics Company
Contracture of Muscle, Thigh, Muscle Rigidity
Differents Intensities of Passive Stretching on ROM, Neuromuscular and Performance in Soccer Players: A Blinded RCT
Intensity is a "qualitative" variable of a muscle stretching protocol, which is very little studied due to its inherent characteristic of the individual being stretched.
- Conditions
- Contracture of Muscle, Thigh, Muscle Rigidity, Strain of Hamstring Muscle (Disorder)
- Trial name
- NCT03150563
- Testing
- Passive static stretch
- Where
- Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Rio Grande do Norte
Dupuytrens Contracture
Injectable Collagenase and Percutaneous Needle Fasciotomy for Dupuytren's Contracture
Comparing injectable collagenase and percutaneous needle fasciotomy for Dupuytren's contracture affecting proximal interphalangeal joints. An open label, medico-independent randomized controlled trial.
- Trial name
- NCT01538017
- Testing
- Xiapex, Percutaneous needle fasciotomy
- Where
- Denmark
- Volunteers
- 50 people
- Sponsor
- Jeppe Lange, MD
Dupuytren's Disease
Retreatment of Recurrent Dupuytren's Contractures
The objectives of this study are to assess the safety and efficacy of AA4500 in the retreatment of recurrent contractures in joints that were effectively treated with AA4500 in a previous Auxilium-sponsored Phase 3 study.
- Trial name
- NCT01498640
- Testing
- Collagenase clostridium histolyticum
- Where
- 13 sites in United States, Australia and 2 more
- Volunteers
- 52 people
- Sponsor
- Endo USA Inc., a Keenova Therapeutics Company
Dupuytren Contracture
Collagenase is a Common Treatment of MCP and PIP Joint Contractures in Dupuytrens Disease
To evaluate the effect of collagenase clostridium histolyticum treatment at the Department of Orthopaedic surgery at Horsens Regional Hospital after minimum one-year follow-up (FU).
- Trial name
- NCT03331926
- Testing
- Xiapex
- Volunteers
- 199 people
- Sponsor
- Jeppe Lange
Cerebral Palsy
Early Intervention in Infants With Cerebral Palsy
Contractures are a frequent cause of reduced mobility in children with Cerebral palsy (CP) already at the age of 2-3 years. Reduced muscle use and muscle growth have been suggested as key factors in the development of…
- Trial name
- CONTRACT (NCT04250454)
- Testing
- CONTRACT
- Where
- Denmark
- Volunteers
- 36 people
- Sponsor
- University of Copenhagen
Osteoarthritis, Dislocations
Epidemiology and Outcomes of Upper Limb Surgery: Analysis of Routine Data
Surgery is a common treatment type for damaged joints, tendons and nerves in the upper limb where conservative measures are inappropriate or have failed.
- Conditions
- Osteoarthritis, Dislocations, Inflammatory Arthritis, Rotator Cuff Tear
- Trial name
- NCT03573765
- Testing
- Shoulder arthroplasty, Elbow arthroplasty, Hand and wrist arthroplasty
- Volunteers
- 8,308,821 people
- Sponsor
- University of Oxford
Contracture of Elbow Joint
Immediate Effects of Superficial Heat Associated With Elongation in the Posttraumatic Elbow Contracture
The elbow contracture is a secondary injury that can occur after direct trauma, causing the patient to have limitations in their range of motion.
- Trial name
- NCT03179098
- Testing
- Modified Weeks protocol, CIVM, GC- Sustained Stretching
- Where
- Brazil
- Volunteers
- 20 people
- Sponsor
- University of Sao Paulo
Hip Joint Contracture
Sonographic Study of Hip Joint in Hockey Players
The aim is to determine whether the game of ice hockey has an effect on structural changes in the hip joint. The parameter to be investigated will be the increased frequency of structural changes of the hip joint in ice hockey…
- Trial name
- NCT05788419
- Testing
- sonography
- Where
- Czechia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Charles University, Czech Republic
Hemophilia, Elbow Joint Contracture
Efficacy of Strength Training in Improving Elbow Range of Motion and Function in Adults With Hemophilia
This is a research study of adults with hemophilia that have limitations in elbow joint motion that is the result of bleeding into the joint.
- Trial name
- NCT03842605
- Testing
- Strength training
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Oregon Health and Science University