Clinical trials: Joint Fixation
Fracture Fixation, Internal
A Clinical Study to Evaluate the Safety and Efficacy of Biologic Hollow Bone Screws
Traditional fracture fixation devices can cause corrosion, allergies, and stress shielding effects. They often require removal after healing, risking secondary damage.
- Trial name
- NCT06942247
- Testing
- Active Comparator: Fracture Fixation (Inion Freedom Screws), Experimental: Fracture Fixation (Biological Hollow Bone Screws)
- Where
- China
- Volunteers
- 160 people
- Sponsor
- FengYafei
Osteoarthritis, Knee
Roentgen Stereophotogrammetric Analysis (RSA) and Dual Energy X-ray Absorptiometry (DEXA) to Evaluate Fixation of Periapatite Coated Triathlon Total Knee Arthroplasty (TKA) Components
The purpose of this study is twofold: 1) to use RSA to determine the migration patterns of the PA coated Triathlon Total Knee Arthroplasty components during the first 2 years postoperatively and thus determine the proportion of…
- Trial name
- NCT01180582
- Testing
- Triathlon Periapatite (PA)-coated Tibial Component
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- Dalhousie University
Osteoarthritis, Knee
Does Tourniquet Use in Total Knee Replacement Improve Fixation
Although a tourniquet may reduce bleeding during total knee replacement (TKA), and thereby improve fixation, it might also cause complications.
- Trial name
- NCT01470482
- Testing
- No use of tourniquet, Tourniquet
- Where
- Sweden
- Volunteers
- 50 people
- Sponsor
- Per Aspenberg
Proximal Interphalangeal Joint Fracture
Evaluation of Suzuki Frame Fixation in Comminuted Fractures of the Proximal Interphalangeal Joint.
This prospective randomized controlled trial aims to evaluate the functional and radiological outcomes of using the Suzuki frame for treating comminuted intra-articular fractures of the proximal interphalangeal (PIP) joint.
- Trial name
- NCT07714356
- Testing
- Suzuki Frame, Standard Conventional Treatment.
- Where
- Egypt
- Volunteers
- 2 people
- Sponsor
- Yehia Mohamed
Arthritis
Long Term Outcomes Follow-up of Glenoid Anchor Peg Component Fixation
The purpose of this study is to investigate if the use of autologous bone graft around the anchor-peg glenoid prosthesis correlates with (1.) bony apposition on computed tomography scans, (2.) decreased radiolucent lines, (3.) a…
- Trial name
- NCT02983357
- Testing
- CT, X-Ray, Physical assessment, Questionnaire
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Nebraska
Anesthesia
Comparison of Two Techniques of Sciatic Nerve Block With Levobupivacaine 0.5% in Orthopedic Surgery
The purpose of this study is to evaluate the latency period (timing between the injection of the local anesthetic and the onset of complete sensory nerve block) of two approaches for ultrasound-guided popliteal sciatic nerve…
- Trial name
- NCT01734954
- Testing
- Sciatic nerve anesthesia blockade at bifurcation., Sciatic nerve blockade 2 cm beyond the bifurcation, Levobupivacaine 0.5%: 20 ml
- Where
- 2 sites in Colombia
- Volunteers
- 66 people
- Sponsor
- CES University
Osteoarthritis, Rheumatoid Arthritis
Tritanium® Study in Japan
The purpose of this study is to evaluate early fixation and stability of the Tritanium cup. It is expected that the Tritanium® cup will be equal to or better than conventional cementless cups in early fixation/stability and meet…
- Conditions
- Osteoarthritis, Rheumatoid Arthritis, Avascular Necrosis of the Femoral Head
- Trial name
- NCT02552069
- Testing
- Tritanium® cup
- Where
- Japan
- Volunteers
- 50 people
- Sponsor
- Stryker Japan K.K.
Radius Fracture Distal, Surgery
Volar Locking Plate Versus External Fixation for Distal Radius Fracture - a Longterm Follow up
A 10-year follow up of a fusion of two earlier published randomized controlled trials. 203 patients with displaced distal radius fractures were randomized to surgery with a volar locking plate or external fixation.
- Conditions
- Radius Fracture Distal, Surgery, Surgery--Complications, Treatment Complication
- Trial name
- EXTEND (NCT05371938)
- Testing
- Volar locking plate, external fixation
- Where
- Sweden
- Volunteers
- 203 people
- Sponsor
- Olof Skoldenberg
Arthrodesis, Degenerative Arthritis
INBONE Total Ankle Arthroplasty(TAA)Using Calcaneal Stem Fixation
The primary objective of this study is to evaluate the radiographic outcomes of Total Ankle Arthroplasty in patients having a calcaneal stem.
- Conditions
- Arthrodesis, Degenerative Arthritis, Rheumatoid Arthritis, Complications; Arthroplasty, Mechanical
- Trial name
- NCT01366989
- Testing
- Radiographic evaluation of previously implanted patients
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Stryker Trauma and Extremities
Thumb Carpometacarpal Arthritis
Suture Fixation System Versus Tendonous Reconstruction in Carpometacarpal (CMC) Arthroplasty
Thumb carpometacarpal (CMC) arthritis affect 1 in 4 females and 1 in 12 males. Patients who fail to respond to conservative treatment may benefit from surgery; however, controversy exists over the most effective surgical…
- Trial name
- NCT01121874
- Testing
- Ligament reconstruction with suture fixation system, Ligament Reconstruction with Tendon Interposition (LRTI)
- Where
- United States
- Volunteers
- 53 people
- Sponsor
- J&M Shuler
Figure Out the Best Method of Fixation for Management of Patients With Diabetic Fracture Ankle
Management of Fracture Ankle in Adults With Uncontrolled Diabetes by Hind Foot Nail With Versus Without Joint Preparation , in Assiut University Hospital
Diabetes is a well-known risk factor for complications following ankle fracture fixation.Current recommendations for operative treatment of ankle fractures in patients with diabetes consist of increased rigid fixation and…
- Trial name
- NCT05039957
- Testing
- joint preparation, without joint preparation
- Where
- Egypt
- Volunteers
- 36 people
- Sponsor
- Assiut University
Closed Fracture Dislocation, Tarsometatarsal Joint, Open Fracture Dislocation, Tarsometatarsal Joint
Fixation Insitu Versus Removal for Midfoot Lisfranc Injuries
This study is a multicenter prospective randomized control trial comparing hardware retention (HR) to removal of hardware (RH).
- Trial name
- FIRM (NCT02374944)
- Testing
- Hardware removal
- Where
- 3 sites in Canada
- Volunteers
- 94 people
- Sponsor
- University of Calgary
Articular Fractures
Single Versus Dual Implant Fixation of Distal Femur Fractures
The goal of this clinical trial is to compare two types of surgical fixation in patients with specific kinds of distal femur fractures.
- Trial name
- PRORP (NCT06286670)
- Testing
- Single Implant Fixation, Dual Implant Fixation
- Where
- 16 sites in United States
- Volunteers
- 144 people
- Sponsor
- Wake Forest University Health Sciences
Foot and Ankle Arthrodesis, Foot and Ankle Osteotomy
Foot and Ankle Arthrodesis or Osteotomy With Io-Fix Type Fixation
The recovery of foot and ankle arthrodesis and osteotomy is still plagued by the problem of delayed consolidation or even pseudo-arthrosis.
- Trial name
- NCT04812353
- Testing
- Follow-up of Io-Fix type fixation
- Where
- Belgium
- Volunteers
- 208 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Osteoarthritis
Evaluation of Bisphosphonate Coated Pins for Extern Fixation in Tibia Osteotomy
The purpose of this study is to evaluate the relative osseomechanical strength of a novel coated pin/screw in a clinical model.
- Trial name
- PFX (NCT01745276)
- Testing
- Biphosfonate, Hydroxylapatit
- Where
- Sweden
- Volunteers
- 20 people
- Sponsor
- Region Skane
Osteoarthritis
Cemented vs. Non-Cemented TSA for OA of the Shoulder
The purpose of the study is to investigate the fixation of the humeral component in total shoulder arthroplasty for primary osteoarthritis of the glenohumeral joint.Our hypothesis is that uncemented fixation of the humerus will…
- Trial name
- NCT00158418
- Testing
- Cemented Humeral Stem, Uncemented Humeral Stem
- Where
- Canada
- Volunteers
- 160 people
- Sponsor
- Fowler Kennedy Sport Medicine Clinic
Fracture of Tibia Proximal Plateau
Immediate Versus Late Weight Bearing After Tibial Plateau Fractures Internal Fixation
Postoperative rehabilitation for tibial plateau fracture generally involves prolonged non-weight bearing time while other protocols use partial weight-bearing and bracing before full weight-bearing is recommended at 9 to 12 weeks…
- Trial name
- NCT05502679
- Testing
- Weight bearing as tolerated, Pragmatic Exercise protocol
- Where
- Egypt
- Volunteers
- 56 people
- Sponsor
- Assiut University
Intra-Articular or Extra-Articular Distal Humerus Fracture, Distal Humerus Fracture
Clinical Outcomes After Treatment of Distal Humerus Fractures With the LORRAINE 2.5/3.5 mm Distal Humerus System
Distal humerus fractures are fractures of the lower part of the upper arm bone near the elbow. These fractures often require surgery using plates and screws to stabilize the bone while it heals.
- Trial name
- NCT07774091
- Testing
- LORRAINE 2.5/3.5 mm Distal Humerus System
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Bonebridge AG
Orthopedic Surgery of Lower Extremity
Evaluation of Continuous Saphenous Nerve Block to Supplement a Continuous Sciatic Nerve Block After Ankle Surgery
A nerve block catheter is a small tube placed next to a nerve through a needle, and the needle is then removed. Numbing medicine is dripped through the tube to reduce pain sensation from the nerve.
- Trial name
- NCT01167907
- Testing
- 0.2% ropivacaine, saline
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Wake Forest University Health Sciences
Osteoarthritis
A Study to Determine the Difference in Low Contact Stress (LCS) Duofix Versus Low LCS Porocoat Knee Systems
The primary objective of this investigation is to test the hypothesis that the Duofix Tibial component results in a reduction of immediate postoperative pain compared to the LCS Porocoat version.
- Trial name
- NCT00733499
- Testing
- LCS Complete Duofix, LCS Complete Porocoat
- Where
- Ireland
- Volunteers
- 206 people
- Sponsor
- DePuy International