Clinical trials: Joint Hypermobility
Degenerative Sacroiliitis, Sacroiliac Joint Disruption
Sacroiliac Joint Fusion With iFuse Implant System (SIFI)
The purpose of this study is to evaluate the use of the iFuse Implant System to treat degenerative sacroiliitis (arthritis of the SI joint) and sacroiliac disruption (abnormal separation or tearing of the sacroiliac joint).
- Trial name
- SIFI (NCT01640353)
- Where
- 26 sites in United States
- Volunteers
- 194 people
- Sponsor
- SI-BONE, Inc.
Ehlers-Danlos Syndrome Hypermobility Type (hEDS)
3D Printed Orthosis for Wrist Instability for Ehlers-Danlos Syndrome Patient
This study will determine if using 3D scanning and 3D printing technology to create an orthosis to improve the quality of life for people with Ehlers Danlos Syndrome (EDS) compared to existing prefabricated orthoses.
- Trial name
- NCT07565636
- Testing
- 3D scanned and 3D printed wrist hand orthosis
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- ELewis
Hypermobility Syndrome, Danlos Disease, Ehlers
Functional Instability in Patients Suffering From Collagen Disease and Joint Hypermobility
A joint is considered "hypermobile" when it has a greater range of motion than normal for a given age, ethnicity or gender. Many people have asymptomatic hyperlaxity in multiple joints, a condition called Generalized Joint…
- Conditions
- Hypermobility Syndrome, Danlos Disease, Ehlers, Collagen Diseases, Joint Hypermobility
- Trial name
- VIPIA (NCT05871216)
- Testing
- Clinical tests and balance evaluation using the Delos Proprioceptive System
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- Istituto Ortopedico Rizzoli
Degenerative Sacroilitis, Sacroiliac Joint Disruption
LOIS: Long-Term Follow-Up in INSITE/SIFI
The purpose of this study is to evaluate the long term safety and effectiveness of SI joint fusion using the iFuse Implant System in patients with degenerative sacroiliitis (DS) and/or sacroiliac joint disruptions (SD).
- Trial name
- LOIS (NCT02270203)
- Testing
- Pelvic CT at 5 years post-op
- Where
- 12 sites in United States
- Volunteers
- 103 people
- Sponsor
- SI-BONE, Inc.
Pes Planus Down Syndrome Patients
Down Syndrome and Effects of Foot Muscle Exercise
Down syndrome (DS) is a common chromosomal pediatric disorder and accounts for approximately 8 % of all congenital anomalies. Children with DS experience delays in Cognitive, Physical, Speech and Language development.
- Trial name
- NCT05251935
- Testing
- Foot Muscle Exercise Protocol, Arch Support Insole and One Leg Balance Activities
- Where
- Pakistan
- Volunteers
- 47 people
- Sponsor
- Ziauddin University
Shoulder Dislocation, Shoulder Pain
Does Shoulder Stabilizations Stabilize Shoulders?
Background: There is no evidence that shoulder stabilization effectively corrects the glenohumeral translation in unstable shoulders, explaining residual apprehension in certain patients.
- Conditions
- Shoulder Dislocation, Shoulder Pain, Joint Instability Syndrome
- Trial name
- NCT02725333
- Testing
- Shoulder Stabilization
- Volunteers
- 11 people
- Sponsor
- La Tour Hospital
Scoliosis Idiopathic, Hypermobility, Joint
Brace Efficiency and Generalized Joint Hypermobility
The goal of this observational study is to learn about effect of generalised joint hypermobility on the effectiveness of the brace in children with Adolesan Idiopatic Scoliosis and who use braces due to brace indication.
- Trial name
- NCT06021314
- Testing
- Brace
- Where
- Turkey (Türkiye)
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Baskent University
Joint Hypermobility, Healty Controls
Prenatal Hormonal Markers and Sleep Characteristics in Young Adults With Joint Hypermobility
Joint hypermobility is a clinical condition characterized by joints having a range of motion beyond their normal limits. Hormonal factors are thought to play a role in the development of joint hypermobility.
- Conditions
- Joint Hypermobility, Healty Controls, Sleep, Androgen Effect
- Trial name
- NCT07157930
- Testing
- The Beighton Scoring system, 2D:4D Digit Ratio
- Where
- Turkey (Türkiye)
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Nigde Omer Halisdemir University
Hypermobility, Joint
Ultrasonographic Evaluation of the Ulnar Nerve in Individuals With and Without Generalized Joint Hypermobility
This study will include 30 individuals diagnosed with Generalized Joint Hypermobility (GJH) based on the Beighton score and 30 healthy controls without GJH. Participants will undergo Tinel's test and the flexion-compression test.
- Trial name
- NCT07044986
- Testing
- no intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Beylikduzu State Hospital
Lipedema, Hypermobility, Joint
Joint Hypermobility and Associated Factors in Patients With Lipedema
The aim of this observational study is to determine the prevalence of joint hypermobility in female patients with lipedema compared to healthy volunteers.
- Trial name
- LIP-HYP (NCT07808242)
- Where
- Turkey (Türkiye)
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Dokuz Eylul University
Headache
Musculoskeletal Impairment in Headaches Attributed to Rhinosinusitis
Neck pain, neck muscle weakness, and limited neck range of motion have been shown in individuals with sinus headaches. Individuals in this previous study self-diagnosed their sinus headaches.
- Trial name
- NCT04222244
- Testing
- No intervention will be administered. We are only performing tests and measures.
- Where
- 7 sites in United States
- Volunteers
- 82 people
- Sponsor
- Des Moines University
Subacromial Impingement Syndrome, Subacromial Bursitis
Subacromial Injection With Corticosteroid Versus Nonsteroidal Anti-inflammatory Drugs (NSAID) in Shoulder Impingement Syndrome
Injection with corticosteroid is one of the most common non-operative interventions in the treatment of subacromial impingement; however, its use is limited by its potential side effects (e.g.
- Trial name
- NSAID (NCT01449448)
- Testing
- Ketorolac, Triamcinolone
- Volunteers
- healthy volunteers welcome
- Sponsor
- Madigan Army Medical Center
Joint Hypermobility
Characteristics of the Functional State of the Musculoskeletal System, Body Awareness, and Quality of Life in Individuals With Joint Hypermobility, Their Associations, and Guidelines for Intervention.
The goal of this observational study is to learn about the characteristics of the functional state of the musculoskeletal system, body awareness, and quality of life in individuals with joint hypermobility, their associations…
- Trial name
- NCT07476976
- Testing
- No intervention
- Where
- Lithuania
- Volunteers
- 511 people, healthy volunteers welcome
- Sponsor
- Lithuanian University of Health Sciences
Hypermobility Syndrome Shoulder, Shoulder Pain Chronic
Resistance Training for Patients With Hypermobility Spectrum Disorders and Shoulder Symptoms: a Feasibility Study
Hypermobility Spectrum Disorders (HSD) is a recent diagnosis that covers joint hypermobility with one or more secondary symptomatic musculoskeletal manifestations.
- Trial name
- NCT03547570
- Testing
- Progressive heavy shoulder resistance training
- Where
- 3 sites in Denmark
- Volunteers
- 12 people
- Sponsor
- University of Southern Denmark
Musculoskeletal Growth and Development
A Study on Associations Between Multidimensional Human Phenotypic Traits and Human Growth and Development
This observational study aims to investigate the associations between multidimensional human phenotypic characteristics and growth and developmental features.
- Trial name
- NCT07857798
- Testing
- Fingerprint Morphological Characteristics
- Where
- China
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Nanfang Hospital, Southern Medical University
Generalized Joint Hypermobility
Sensorimotor Organization in Individuals With General Joint Hypermobility
This study is the first to examine the effect of sole sensory training on sensorimotor organization in individuals with GEH. Individuals with a Beighton score of 5 and above were included in the study.
- Trial name
- NCT06988631
- Testing
- Sensory treatment, foot care booklet
- Where
- Turkey (Türkiye)
- Volunteers
- 65 people
- Sponsor
- Gazi University
Lipedema, Hypermobility Syndrome (Disorder)
Investigation of Medial Longitudinal Arch and Foot Function in Patients With Lipedema
Lipedema is a chronic adipose tissue disorder that commonly leads to joint laxity, hypermobility, and functional limitations, yet its impact on foot morphology has not been systematically examined.
- Conditions
- Lipedema, Hypermobility Syndrome (Disorder), Pes Planus, Joint Hypermobility
- Trial name
- NCT07294014
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Marmara University
Healthy
The Effect of Estrogen and Progesterone Levels on Knee and Ankle Joint Laxity
The proposed research is an observational study designed to compare estrogen and progesterone serum levels with knee and ankle joint laxity, and muscle reaction time as a measure of neuromuscular function.
- Trial name
- NCT00005923
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- National Center for Research Resources (NCRR)
Musculoskeletal Diseases, Joint Instability
Wrist Stabilizing Exercise Versus Hand Orthotic Intervention for Persons With Hypermobility
The goal of this study is to investigate if a Wrist Stabilizing Exercise Programme, WSE, compared to Conventional Intervention use of orthosis in daily activities, HO in persons with Hypermobility Spectrum Disorders, HSD or…
- Trial name
- NCT05696041
- Testing
- Static strength training program or/and Dynamic strength training program of the hand
- Where
- Sweden
- Volunteers
- 169 people
- Sponsor
- Göteborg University
Benign Joint Hypermobility Syndrome, Wheezing
A Study to Assess Benign Joint Hypermobility Syndrome in Children With a History of Wheezing or Asthma
The purpose of this study is to assess benign joint hypermobility syndrome (BJHS) in children with a history of wheezing or asthma.
- Conditions
- Benign Joint Hypermobility Syndrome, Wheezing, Asthma
- Trial name
- NCT02163096
- Where
- 3 sites in United States
- Volunteers
- 23 people
- Sponsor
- University of Louisville