Clinical trials: Joint Osteoarthritis, open to volunteers
Knee Osteoarthristis, Hip Osteoarthritis
Clinical Validation of SMARTDIAGO for Remote Functional Assessment of Musculoskeletal Conditions
Clinical validation of SMARTDIAGO, an artificial intelligence-based system for remote functional assessment of patients with musculoskeletal disorders and functional frailty.
- Conditions
- Knee Osteoarthristis, Hip Osteoarthritis, Spine Disease, Shoulder Disease
- Trial name
- SMARTDIAGO (NCT07880210)
- Testing
- SMARTDIAGO Remote Functional Assessment
- Where
- 2 sites in Chile
- Volunteers
- 350 people
- Sponsor
- University of Chile
Osteoarthritis
Efficacy Test of Curcuminoid Standardized Turmeric Capsules to Improving Inflammatory Biomarkers in Osteoarthritis Genu
The goal of this clinical trial is to learn if Curcuminoid Standardized Turmeric Capsules works to treat Osteoarthritis Genu in adults. It will also learn about the safety of Curcuminoid Standardized Turmeric Capsules.
- Trial name
- ETCS (NCT07183215)
- Testing
- Curcuminoid Standardized Turmeric Capsules
- Where
- Indonesia
- Volunteers
- 72 people
- Sponsor
- Gadjah Mada University
Knee Osteoarthritis
Effects of Music During Walking on Pain and Muscle Activation in People With Chronic Pain Due to Knee Osteoarthritis
The purpose of this research study is to compare muscle activation, changes in pain sensitivity, and brain function, between different walking conditions, including walking to music, walking to metronome, and walking without…
- Trial name
- NCT07537114
- Testing
- Rhythmic Auditory Stimulation with music, Rhythmic Auditory Stimulation with metronome, Control
- Volunteers
- 20 people
- Sponsor
- Boston University Charles River Campus
Osteoarthritis
Synovial Tissue as a Biomarker in the Early Management of Osteoarthritis
Osteoarthritis is a common disease whose prevalence continues to increase. To date, there is no medical treatment that has proven effective, and only symptomatic treatments exist, mainly to reduce pain.
- Trial name
- SYNPA (NCT07473414)
- Testing
- synovial biopsies
- Where
- 2 sites in France
- Volunteers
- 30 people
- Sponsor
- Nantes University Hospital
Osteoarthritis (OA) of the Knee
Novel Extended-Release Bupivacaine Polymer for Sustained Pain Relief Following Total Knee Arthroplasty
Participants are being invited to take part in a research study about pain control after total knee replacement surgery (also called total knee arthroplasty or TKA).
- Trial name
- NCT07775248
- Testing
- Periarticular Injection, Adductor Canal Block, Bupivacaine-Meloxicam
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Henry Ford Health System
Osteoarthritis, Knee
Undenatured Type II Collagen for Knee Osteoarthritis Pain
This randomized, controlled, double-blind, three-arm parallel clinical trial will evaluate the efficacy and safety of undenatured type II collagen products on joint pain in adults diagnosed with knee osteoarthritis.
- Trial name
- NUVICOL (NCT07870967)
- Testing
- Nuvicol II, Nuvicol SII
- Where
- Spain
- Volunteers
- 120 people
- Sponsor
- Universidad Católica San Antonio de Murcia
Osteoarthritis (OA) of the Knee
Total Osteo-Cartilage Replacement for the Treatment of Osteoarthritis of Knee
Young patients who require total knee arthroplasty with metallic and plastic implants will undergo femoral condyle cartilage and top of the tibia with meniscus replacement.
- Trial name
- NCT07769632
- Testing
- Total osteo-cartilage replacement of the distal femur and proximal tibia, including medial and lateral meniscus., allogenic bone and cartilage graft
- Where
- Bahrain
- Volunteers
- 10 people
- Sponsor
- AlSalam Hospital
Osteoarthritis
Thromboxane A2 and Osteoarthritis
TXA2 inhibits the expression of the primary marker of thermogenesis (UCP1) while prostacyclin (PGI2), another metabolite derived from arachidonic acid, enhances its expression.
- Trial name
- NCT05593640
- Testing
- biological samples
- Where
- France
- Volunteers
- 20 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Osteo Arthritis Knee and Hip
Predicting The Right Advice at The Right Time in Patients With Hip and Knee OsteoArthritis: the e-cOAch Cross-over.
This study aims to learn how symptoms and daily functioning change over time in people with hip or knee osteoarthritis (OA). The goal is to use this information to build computer models that can predict these changes.
- Trial name
- e-cOAch (NCT07423858)
- Testing
- Physical Activity program, Sleep program, Weight management program
- Where
- Netherlands
- Volunteers
- 600 people
- Sponsor
- UMC Utrecht
Osteoarthritis (Knee), Arthroplasties, Knee Replacement
Feasibility of Good Boost+ for Adults Awaiting Total Knee Replacement
The goal of this randomised controlled feasibility trial is to find out whether it is possible to run a larger study of the Good Boost+ community based rehabilitation programme for people waiting for a primary total knee…
- Trial name
- NCT07532785
- Testing
- Good Boost+, Usual NHS Care
- Where
- United Kingdom
- Volunteers
- 48 people
- Sponsor
- King's College Hospital NHS Trust
Osteoarthritis of the Knee
Bone Marrow Aspirate Concentrate (BMAC) vs Corticosteroid Injection
Prospective single-masked (study participant will be masked), randomized controlled trial to examine the influence of BMAC on patient-reported outcomes (PROs) in patients with primary knee osteoarthritis.
- Trial name
- BMAC (NCT05985785)
- Testing
- Autologous bone marrow aspirate concentrate (BMAC), Corticosteroid injections, Crossover Autologous bone marrow aspirate concentrate (BMAC)
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Rush University Medical Center
Arthrosis
Changes in Physical Activity, Sleep and Knee Function After Same-Day Discharge Knee Arthroplasty
The goal of this observational study is to examine changes in physical activity, sleep quality, knee extension and flexion strength, knee range of motion, and patient-reported outcomes before and after same-day discharge knee…
- Trial name
- ORTOMOVE (NCT07840391)
- Testing
- Medial unicompartmental knee arthroplasty (UKA), Total knee arthroplasty (TKA)
- Where
- 2 sites in Finland
- Volunteers
- 120 people
- Sponsor
- Turku University Hospital
Osteoarthritis, Tendinitis
Evaluation of Outcomes With Umbilical Cord Allograft for Musculoskeletal Conditions Musculoskeletal Conditions
The aim of the study is to determine the efficacy of an Amniotic Fluid Tissue Product for pain relief and functional improvements for all types of musculoskeletal conditions.
- Conditions
- Osteoarthritis, Tendinitis, Sports Injury, Degenerative Disc Disease
- Trial name
- NCT03390920
- Testing
- Umbilical Allograft
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- R3 Stem Cell