Clinical trials: Joint Stiffness
Osteoarthritis, Osteoarthritis, Knee
A Clinical Trial Investigating the Effect of Salmon Bone Meal on Osteoarthritis Among Men and Women
The purpose of this study is to evaluate the efficacy of hydrolyzed collagen in osteoarthritis.
- Conditions
- Osteoarthritis, Osteoarthritis, Knee, Osteoarthritis, Hip
- Trial name
- NCT05070871
- Testing
- Hydrolyzed Collagen, CalGo
- Where
- 3 sites in Norway
- Volunteers
- 98 people
- Sponsor
- Hofseth Biocare ASA
Morbid Obesity, Hypertension
Prevention of Coronary Heart Disease in Morbidly Obese Patients
The changes in risks of developing coronary heart disease in patients with morbid obesity after different weight loss interventions have not been extensively studied.
- Conditions
- Morbid Obesity, Hypertension, Type 2 DM, Obstructive Sleep Apnea
- Trial name
- SphCor (NCT00626964)
- Testing
- Bariatric Surgery, Conservative Treatment:
- Where
- Norway
- Volunteers
- 200 people
- Sponsor
- The Hospital of Vestfold
Pain, Joint Stiffness
Persistent Postoperative Pain and Joint Stiffness After Total Knee Arthroplasty Performed for Osteoarthritis
Persistent pain and joint stiffness after surgery may interfere with recovery and adversely affect quality of life in up to 40% of patients who have undergone total knee arthroplasty.
- Trial name
- NCT02626533
- Testing
- Total Knee Arthroplasty
- Where
- United States
- Volunteers
- 179 people
- Sponsor
- Hospital for Special Surgery, New York
Adhesive Capsulitis of Shoulder, Frozen Shoulder
The Combined Effect of Mulligan Technique and Scapular Mobilization in Shoulder Adhesive Capsulitis
The shoulder joint capsule is a fibrous sheath that encloses and stabilizes the structures of the shoulder joint, extending from the anatomical neck of the humerus to the rim of the glenoid fossa.
- Conditions
- Adhesive Capsulitis of Shoulder, Frozen Shoulder, Shoulder Pain and Stiffness
- Trial name
- NCT07356947
- Testing
- Mulligan Technique with Scapular Mobilization, Conventional Physiotherapy
- Where
- Egypt
- Volunteers
- 38 people
- Sponsor
- Deraya University
Joint Pain, Musculoskeletal Pain
IDEA-033 Open Label Study
The main aim of the study is to evaluate safety, efficacy, compliance, and usage of epicutaneously applied IDEA-033 in joint / musculoskeletal pain or soft tissue inflammation.
- Conditions
- Joint Pain, Musculoskeletal Pain, Stiffness, Soft Tissue Inflammation in Designated Target Area(s)
- Trial name
- NCT00372333
- Testing
- IDEA-033
- Where
- Germany
- Volunteers
- 491 people
- Sponsor
- IDEA AG
Hemophilia, Postural; Defect
Posture Analysis for Patients With Haemophilia
Hemophilia A and B are inherited disorders characterized by deficient or missing coagulation factors VIII or IX, respectively, of which the main long-term clinical manifestation is joint damage.
- Conditions
- Hemophilia, Postural; Defect, Muscle Disorder
- Trial name
- NCT05173129
- Testing
- Posture Analysis
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Cukurova University
Degenerative Joint Disease
Hyaluronic Acid and Adelmidrol (Hyadrol®) in Patients With Degenerative Joint Disease
Osteoarthritis is a major cause of chronic musculoskeletal pain. Behind this disorder there is a process of chronic neuroinflammation due to the overactivation of mast cells at the tissue level.
- Trial name
- NCT06506656
- Testing
- Hyadrol®
- Where
- Italy
- Volunteers
- 59 people
- Sponsor
- University of Roma La Sapienza
Osteoarthritis
Efficacy & Safety Study Evaluating Natural Eggshell Membrane (NEM) in the Treatment of Osteoarthritis
The purpose of this study is to evaluate the effectiveness of Natural Eggshell Membrane (NEM) for the relief of pain and stiffness associated with moderate osteoarthritis of the knee and to compare the effectiveness of NEM to…
- Trial name
- OPTION (NCT00750477)
- Testing
- NEM
- Where
- 3 sites in United States
- Volunteers
- 67 people
- Sponsor
- ESM Technologies, LLC
Exercise-induced Joint Pain, Exercise-induced Joint Stiffness
NEM® + KD PUR® Fish Oil Versus Placebo in Exercised-induced Joint Pain, Stiffness, & Cartilage Turnover in Healthy Men & Women
This study is intended to evaluate the effect of the dietary supplement combination of NEM® brand eggshell membrane + KD PUR® brand fish oil versus placebo in reducing exercise-induced joint pain, stiffness \& cartilage turnover…
- Conditions
- Exercise-induced Joint Pain, Exercise-induced Joint Stiffness, Exercise-induced Joint Cartilage Turnover
- Trial name
- Move3 (NCT04215198)
- Testing
- Move3™ (NEM® brand eggshell membrane + KD PUR® brand fish oil)
- Where
- United States
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- ESM Technologies, LLC
Bruxism, Posture
Determining the Relationship Between Posture, Muscle Stiffness, Pain, and Jaw Functionality in Individuals With Bruxism
Bruxism is a repetitive jaw-muscle activity characterized by teeth clenching and/or grinding, often associated with temporomandibular joint dysfunction, pain, and impaired jaw function.
- Conditions
- Bruxism, Posture, Sleep Quality, Pain Assessment
- Trial name
- Bruxism (NCT07560670)
- Testing
- Bruxism Assessment Form, Clinical Examination, Patient Evaluation Form
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Istanbul Kent University
Arthroplasty Complications, Fibrosis
Physiotherapy for Arthrofibrosis Following Knee Replacement.
This research aims to develop an optimal physiotherapy intervention for people with arthrofibrosis (stiffness due to scar tissue) after total knee replacement (TKR). We will develop an optimal intervention by conducting: 1.
- Conditions
- Arthroplasty Complications, Fibrosis, Knee Joint Contracture
- Trial name
- ReSTART (NCT05459259)
- Testing
- Interviews and Delphi Survey
- Where
- United Kingdom
- Volunteers
- 145 people
- Sponsor
- University of Nottingham
Degenerative Osteoarthritis, Rheumatoid Arthritis
All Polyethylene Tibia-VEGA Kiel
Obligatory Post-Marketing Clinical Follow-up (PMCF) as part of the post marketing surveillance plan for the product under investigation For this PMCF only CE-marked medical devices will be used within their intended purpose and…
- Conditions
- Degenerative Osteoarthritis, Rheumatoid Arthritis, Post-traumatic; Arthrosis, Other Instability, Knee
- Trial name
- APT-VEGA_KI (NCT02756702)
- Testing
- All-Poly
- Where
- Germany
- Volunteers
- 70 people
- Sponsor
- Aesculap AG
Joint Health, Mobility
A Clinical Trial to Investigate the Efficacy and Safety of a Plant-based Cetylated Fatty Acids (CFA) on Knee Pain and Stiffness in Healthy Adults With Persistent Knee Pain
The goal of this clinical trial is to investigate the efficacy and safety of plant-derived cetylated fatty acids (CFA) on joint health and mobility in adults with persistent knee pain.
- Conditions
- Joint Health, Mobility, Knee Pain
- Trial name
- NCT07695714
- Testing
- Plant-derived cetylated fatty acids (CFA)
- Where
- Canada
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Everwell Health
Adhesive Capsulitis, Adhesive Capsulitis of Unspecified Shoulder
Suprascapular Nerve Block to Improve Tolerance and Outcomes of Shoulder Hydrodistension in Adhesive Capsulitis
Adhesive capsulitis ("frozen shoulder") causes significant pain and loss of shoulder mobility. Shoulder hydrodistension is an established treatment that can improve movement and reduce symptoms, but the procedure itself may be…
- Conditions
- Adhesive Capsulitis, Adhesive Capsulitis of Unspecified Shoulder, Adhesive Capsulitis, Shoulder, Frozen Shoulder
- Trial name
- SHINE (NCT07380087)
- Testing
- Shoulder Hydrodistention, suprascapular nerve block
- Where
- Portugal
- Volunteers
- 50 people
- Sponsor
- Universidade do Porto
Rheumatoid Arthritis - Hand Joint, Osteoarthritis Hand
Effectiveness of an Exercise Program and Education Through a Mobile Application for the Management of Patients With Hand Osteoarthritis and Rheumatoid Arthritis
Strengthening and stretching exercise programs, and recommendations to protect the affected joint have shown to be effective both clinically and economically in conditions such as hand osteoarthritis and hand rheumatoid…
- Conditions
- Rheumatoid Arthritis - Hand Joint, Osteoarthritis Hand, Pain, Mobility Limitation
- Trial name
- NCT04263974
- Testing
- Smartphone Application, Conventional treatment
- Where
- Spain
- Volunteers
- 213 people
- Sponsor
- University of Seville
Neck Pain, Work-related Injury
Clinical Outcomes, Viscoelastic Properties and Central Pain Mechanisms After Eccentric Training in Neck/Shoulder Pain
Objectives: The aims are to 1) evaluate the clinical impact of eccentric training in female computer users with chronic NSP, 2) compare pressure hyperalgesia, temporal summation of pain (TSP), and conditioned pain modulation…
- Conditions
- Neck Pain, Work-related Injury, Shoulder Pain
- Trial name
- NCT03474705
- Testing
- Eccentric Training Protocol
- Where
- Spain
- Volunteers
- 20 people
- Sponsor
- University of Seville
Joint Discomfort, Joint Pain, Stiffness, Function
JDS-HF3.0 Supplementation on Menopause Related Quality of Life Outcomes in Postmenopausal Women
The goal of this interventional study is to evaluate whether the study product can help improve quality of life and reduce common menopause symptoms-such as joint discomfort, hot flashes and night sweats-in women aged 50-70.
- Conditions
- Joint Discomfort, Joint Pain, Stiffness, Function, Joint Pain, Hot Flashes
- Trial name
- NCT07238478
- Testing
- JDS-HF3.0
- Where
- United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Bonafide Health
Knee Osteoarthritis
The Effect of "Laying on of Hands" in Older Women With Knee Osteoarthritis
Osteoarthritis (OA) is the most common form of chronic degenerative joint disease, as well as the main cause of pain and disability in older persons worldwide.
- Trial name
- NCT02917356
- Testing
- Spiritual laying on of hands (SP), Non-spiritual Laying on of Hands, Control group
- Where
- Brazil
- Volunteers
- 105 people
- Sponsor
- Federal University of Juiz de Fora
Rheumatoid Arthritis
Efficacy of Lodotra®(Prednisone) in Reduction of Morning Stiffness Duration(K-IMPROvE)
This study is multicenter, Ph IV, single arm, interventional study to assess relative reduction of morning stiffness of Lodotra® in Rheumatoid Arthritis patients.Study medication will start after study visit at baseline (week 0…
- Trial name
- NCT02072200
- Testing
- Lodotra®
- Where
- South Korea
- Volunteers
- 147 people
- Sponsor
- Mundipharma Korea Ltd
Posterior Shoulder Tightness, Subacromial Impingement Syndrome
The Immediate Effects of Soft Tissue Mobilization on Posterior Shoulder Tightness in Overhead Athletes With Subacromial Pain Syndrome
The aim of this study is to investigate the immediate effects of soft tissue mobilization on shoulder mobility, pain, scapular kinematics and muscle activation and muscle Stiffness in symptomatic overhead athletes with posterior…
- Trial name
- NCT07005856
- Testing
- Soft tissue mobilization, Stretching, Hot pack
- Where
- Taiwan
- Volunteers
- 54 people
- Sponsor
- National Yang Ming Chiao Tung University