Clinical trials: Juvenile-Onset Diabetes
Type 1 Diabetes (T1D)
Universal Type 1 Diabetes Screening in Pediatrics
This study examines how population-based screening for type 1 diabetes (T1D) using islet autoantibodies (i.e., immune system proteins) can be incorporated into pediatric primary care during routine well-child visits.
- Trial name
- NCT07612475
- Testing
- Set of implementation strategies
- Where
- 8 sites in United States
- Volunteers
- 9,500 people
- Sponsor
- Northwestern University
Type 1 Diabetes
PREVENTKD (Prevent Risks by Early interVEntion at Nighttime in Type 1 Diabetes for Kidney Disease)
The purpose of this study is to determine if the early treatment with a blood pressure medication (an ACE Inhibitor) can prevent or delay the development of kidney disease (microalbuminuria) in patients with Type 1 diabetes who…
- Trial name
- PREVENTKD (NCT00729365)
- Testing
- Ramipril
- Where
- 6 sites in United States
- Volunteers
- 65 people
- Sponsor
- Northwestern University
Type 1 Diabetes Mellitus
Afrezza Safety and Pharmacokinetics Study in Pediatric Patients
Primary Objective: -To assess the safety and tolerability of Afrezza in children ages 4 to 17 years with type 1 diabetes mellitus (T1DM).
- Trial name
- NCT02527265
- Testing
- Afrezza
- Where
- 13 sites in United States
- Volunteers
- 30 people
- Sponsor
- Mannkind Corporation
Diabetes Mellitus, Type 2, Diabetes Mellitus, Type 1
Continuous Glucose Monitoring in Dialysis Patients With Diabetes
The primary objective of this multicenter, randomized controlled trial is to assess whether the intermittent or continuous use of continous glucose monitoring can enhance glycaemic control among dialysis patients with type 1 or…
- Conditions
- Diabetes Mellitus, Type 2, Diabetes Mellitus, Type 1, Continuous Glucose Monitoring, Haemodialysis
- Trial name
- NCT06641765
- Testing
- Continous Glucose Monitoring
- Where
- 5 sites in Denmark
- Volunteers
- 96 people
- Sponsor
- Bo Feldt-Rasmussen
Diabetes Mellitus
Genetics of Type 1 Diabetes in Chinese Adolescents and Youth
primary outcome: To explore the genetic susceptibility of diabetes in Chinese adolescent and youth. secondary outcomes: 1. To classify diabetes by gene detection in Chinese adolescent and youth. 2.
- Trial name
- NCT01938365
- Where
- China
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Shanghai Jiao Tong University School of Medicine
Diabetic Children
IgE-mediated Allergies Among Type 1 Diabetes Mellitus Children, Single Centre Observational Study
an interviewer-administrated questionnaire was designed to take history of allergy in diabetic child come to outpatient clinic fulfilling inclusion criteria and used to collect data.
- Trial name
- NCT05596656
- Testing
- skin prick test
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Mansoura University Children Hospital
Coronary Disease, Myocardial Infarction
Chronical Illness-related Limitations of the Ability to Cope with Rising Temperatures: an Observational Study, 2nd Wave
The CLIMATE-II Observational Study examines to what extent chronically ill patients experience adverse health effects because of heat and whether the patients' specific health behavior, somatosensory amplification, risk and…
- Conditions
- Coronary Disease, Myocardial Infarction, Heart Failure, Arrhythmias, Cardiac
- Trial name
- CLIMATE-II (NCT06407154)
- Where
- Germany
- Volunteers
- 578 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Diabetes Mellitus, Type 1
Effects of Web-Based Health Information on Risk Behavior for Youth With Type 1 Diabetes in College
Adolescence and emerging adulthood are critical periods during which health outcomes may be imperiled for youth with Type 1 Diabetes (T1D).
- Trial name
- NCT02883829
- Testing
- Peer-Based Web-Based Health Information, Provider-Based Web-Based Health Information
- Where
- United States
- Volunteers
- 138 people
- Sponsor
- Boston Children's Hospital
Type 1 Diabetes
Pilot Study 3 of Outpatient Control-to-Range: Safety and Efficacy With Day-and-Night In-Home Use
The purpose of this study is to see if an automated insulin management system ("study system") can safely be used at home to manage blood sugar.
- Trial name
- CTR3 (NCT02137512)
- Testing
- Closed-Loop Control System, Sensor-Augmented Pump (SAP)
- Where
- 6 sites in United States, France and 2 more
- Volunteers
- 30 people
- Sponsor
- Jaeb Center for Health Research
Type 1 Diabetes Mellitus
A Study Comparing LY900014 to Insulin Lispro (Humalog) in Children and Adolescents With Type 1 Diabetes
The reason for this study is to compare the study drug LY900014 to insulin lispro (Humalog) in children and adolescents with type 1 diabetes (T1D).
- Trial name
- PRONTO-Peds (NCT03740919)
- Testing
- LY900014, Insulin Lispro, Insulin Glargine
- Where
- 111 sites in United States, Austria and 16 more
- Volunteers
- 751 people
- Sponsor
- Eli Lilly and Company
Diabete Type 1, Educational Videos
Interactive Educational Video for Paediatric Type 1 Diabetes
The primary aim of this study is to evaluate the effectiveness of an interactive educational video (Luca's Journey: Managing Type 1 Diabetes) delivered in addition to the standard educational programme, in improving metabolic…
- Trial name
- Intedu (NCT07639307)
- Testing
- Interactive Educational Video (Luca's Journey: Managing Type 1 Diabetes), Traditional Face-to-Face Education
- Volunteers
- 110 people
- Sponsor
- G. d'Annunzio University
Diabetes Mellitus, Type 1
UVA Islet Cell Transplantation in Patients With Type I Diabetes
This protocol will provide islet cell transplantation to two separate populations in need of a pancreas transplant: Group I: Islet Cell Transplantation in Type I Diabetics without Kidney Problems Group II: Islet Cell…
- Trial name
- NCT00605592
- Testing
- Pancreatic Islets of Langerhans Cell Transplant
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Virginia
Type 1 Diabetes Mellitus, Type 2 Diabetes Mellitus
CGM Utilization With IV Insulin EndoTool and Subcutaneous Insulin in the Neuro ICU
The goal of this study (CGM utilization with IV Insulin EndoTool and Subcutaneous Insulin in the Neuro ICU) is to understand how CGM technology utilized in conjunction with EndoTool IV insulin could improve glycemic management in…
- Conditions
- Type 1 Diabetes Mellitus, Type 2 Diabetes Mellitus, Hyperglycemia
- Trial name
- NCT05857007
- Testing
- Libre 2.0 CGM in patients taking subcutaneous insulin with concomitant high dose glucocorticoids
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Wake Forest University Health Sciences
Diabetes Mellitus, Type 1 Diabetes
Tandem Predictive Low Glucose Suspend Inpatient Feasibility Study
The goal of this study is to assess the functionality of an integrated predictive low glucose suspend system designed to minimize the incidence and duration of hypoglycemia by suspending insulin delivery if hypoglycemia is…
- Conditions
- Diabetes Mellitus, Type 1 Diabetes, Insulin Pump
- Trial name
- NCT02877771
- Testing
- t:slim insulin pump with predictive low glucose suspend
- Where
- 2 sites in United States
- Volunteers
- 10 people
- Sponsor
- Tandem Diabetes Care, Inc.
Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2
Application of UCPCR as a Testing Tool for Identification of MODY Patients in the UAE
The study aims to investigate the validity of 2 hour post-prandial UCPCR test in paediatric and adult patients with diabetes duration greater than 2 and 5 years, respectively, for the purposes of distinguishing between patients…
- Conditions
- Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2, Maturity-onset Diabetes of the Young
- Trial name
- NCT03607604
- Testing
- Next generation sequencing (NGS)
- Where
- United Arab Emirates
- Volunteers
- 778 people, healthy volunteers welcome
- Sponsor
- Imperial College London Diabetes Centre
Type I Diabetes
Measurement of Total Retinal Blood Flow in Patients With Diabetes and Healthy Subjects
The prevalence of diabetes and diabetes-associated complications is still increasing. Several major long-term complications of diabetes such as cardiovascular disease, chronic renal failure, diabetic retinopathy and others relate…
- Trial name
- NCT01843114
- Testing
- FDOCT, Dynamic Vessel Analyzer
- Where
- Austria
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Alopecia Areata, Depressive Episode
The Epidemiology, Management, and the Associated Burden of Related Conditions in Alopecia Areata
This study series consists of four related studies and aims to explore and describe many important elements of alopecia areata over three key areas: (1) the current epidemiology of alopecia areata, (2) the prevalence and…
- Conditions
- Alopecia Areata, Depressive Episode, Recurrent Depressive Disorder, Anxiety Disorders
- Trial name
- NCT04239521
- Testing
- Exposure of interest (studies 2 & 3).
- Where
- United Kingdom
- Volunteers
- 51,955 people
- Sponsor
- Momentum Data
Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2
Implementing Continuous Glucose Monitoring in Primary Care for Patients With Diabetes
The overarching goal of this study is to decrease disparities and increase access to continuous glucose monitoring (CGM) for patients with diabetes, regardless of where people receive their diabetes care.
- Conditions
- Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2, Continuous Glucose Monitoring
- Trial name
- PREPARE4CGM (NCT05336214)
- Testing
- Virtual CGM initiation service, Online educational module on CGM, Practice facilitation
- Where
- United States
- Volunteers
- 190 people
- Sponsor
- University of Colorado, Denver
Diabetes Mellitus, Type 1
The Diabetes Patient-Reported Outcome Measures Trial
The study aim to evaluate the use of Patient-Reported Outcome Measures in clinical diabetes consultations.
- Trial name
- DiaPROM (NCT03471104)
- Testing
- PAID in clinical diabetes consultations
- Where
- Norway
- Sponsor
- Haukeland University Hospital
Diabetes Mellitus, Type 1
The Effects of a Low Carbohydrate, Non-Ketogenic Diet Versus Standard Diabetes Diet on Glycemic Control in Type 1 Diabetes
This randomized, crossover nutrition intervention seeks to examine the effects of a non-ketogenic low carbohydrate (CHO) diet (60-80g per day) on glycemic control, lipids, and markers on inflammation in individuals with Type 1…
- Trial name
- T1DLoCHO (NCT03544892)
- Testing
- Low carbohydrate diet, Standard of care diet
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- University of Oklahoma
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