Clinical trials: Keloid Scar
Keloid
Calcium Electroporation for the Treatment of Keloids
The purpose of this study is to evaluate the effect of calcium electroporation on keloids.
- Trial name
- NCT01941914
- Testing
- Calcium chloride
- Where
- Denmark
- Volunteers
- 7 people
- Sponsor
- Herlev Hospital
Keloid
Efficacy, Safety, and Tolerability of Remlarsen (MRG-201) Following Intradermal Injection in Subjects With a History of Keloids
Remlarsen (MRG-201) is designed to mimic the activity of a molecule called miR-29 that decreases the expression of collagen and other proteins that are involved in scar formation.
- Trial name
- NCT03601052
- Testing
- Remlarsen
- Where
- 4 sites in United States
- Volunteers
- 14 people
- Sponsor
- miRagen Therapeutics, Inc.
Cicatrix, Hypertrophic, Keloid
Influence of a Silicone Gel (Dermatix®) on Thoracic Scar Formation After Harvesting of Autologous Rib Cartilage
So far the evaluation of scar treatment was based on subjective criteria. The patient groups were divided into treated versus non-treated. In this study we use patients undergoing ear reconstruction with autologous rib cartilage.
- Trial name
- NCT00565552
- Testing
- Silicone gel (Dermatix®)
- Where
- Germany
- Volunteers
- 20 people
- Sponsor
- University Hospital Schleswig-Holstein
Keloid, Surgical Scar
Safety and Efficacy of Infrared Diode Laser on Improvement of Scar and Prevention of Recurrence of Excised Keloid
A pilot study will be conducted on 2 type of subjects, one with plastic surgery scar with a randomization of laser treated portions, and other with keloid excision scar with a complete laser treatment.
- Trial name
- NCT01158196
- Testing
- infra-red diode laser
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Ekkyo
Keloid
Bleomycin Jet Injections in Keloids
This is a single center, double-blind (patient and investigator), randomized, placebo-controlled study with a split-lesion design, in which selected keloids will receive three consecutive treatments of a) bleomycin and b) placebo…
- Trial name
- NCT04582305
- Testing
- Bleomycin, Normal saline
- Where
- Netherlands
- Volunteers
- 14 people
- Sponsor
- Erasmus Medical Center
Skin Diseases, Keloid
Phase 1 Study of HF-LED-RL in Fitzpatrick Skin Types I to III
The goal of this study is to establish the safety of high fluence LED-RL at fluence of 480 J/cm2 and 640 J/cm2 in healthy non-Hispanic, Caucasian subjects.
- Conditions
- Skin Diseases, Keloid, Scar, Fibrosis
- Trial name
- NCT03433222
- Testing
- HF-LED-RL Phototherapy, Mock Therapy
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- VA Northern California Health Care System
Keloid, Keloid Scar Following Surgery
Post-Surgical Injection With Triamcinolone Versus Triamcinolone/Fluorouracil in Treatment of Keloids
There have been many modalities utilized in the treatment of keloids of the head and neck, however none have been universally successful.
- Trial name
- NCT04710719
- Testing
- Triamcinolone Injection, Triamcinolone Injection and 5-fluorouracil injection
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Our Lady of the Lake Hospital
Keloid Scar
Treatment of Keloids With Fractional Erbium Laser-Assisted 5-Fluorouracil Versus Laser-Assisted Corticosteroid
This is a split-scar study with a target sample size of 20. There are two interventions: fractional erbium:YAG-assisted drug delivery of 5-fluorouracil and fractional erbium:YAG-assisted drug delivery of triamcinolone acetonide.
- Trial name
- NCT04786210
- Testing
- Fractional erbium:YAG-assisted drug delivery of 5-fluorouracil, Fractional erbium:YAG-assisted drug delivery of triamcinolone acetonide
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- NYU Langone Health
Keloid Scar
A Retrospective Evaluation of Superficial Radiation Therapy (SRT) and Keloid Scars.
Keloid formation in response to skin trauma inflicts about 18 million individuals. A key impediment in successful treatment of keloids is that the predominant treatments, particularly surgical excision and shaving, tend to…
- Trial name
- NCT03693924
- Testing
- SRT-100
- Volunteers
- 100 people
- Sponsor
- Sensus Healthcare
Keloid
Epidemiology Study of Keloid
Although keloid is a very common condition; there are no statistics as to its true incidence and prevalence, neither in United States, nor elsewhere in the world.
- Trial name
- NCT01423383
- Where
- United States
- Volunteers
- 100,000 people, healthy volunteers welcome
- Sponsor
- Tirgan, Michael H., M.D.
Hypertrophic Scar, Keloid Scar
A Substantial Equivalence Study of RD04723 and Predicate Device
The purpose of this study is to determine whether a developmental formulation is substantially equivalent to the predicate device in the treatment of hypertrophic and keloid scars.
- Trial name
- NCT01736969
- Testing
- RD047-023, Predicate Device
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Oculus Innovative Sciences, Inc.
Keloid
Genetic Analysis of Keloids
Keloids have a strong genetic component. The goal of this study is to identify genes and regulatory elements on chromosomes that are the cause for keloids or contribute to keloid scarring.
- Trial name
- NCT01619553
- Where
- United States
- Volunteers
- 7,000 people
- Sponsor
- UConn Health
Keloid
High Dose Rate Brachytherapy for Treatment of Keloids
This prospective study evaluates the outcome of surgical excision with adjuvant high-dose-rate brachytherapy for the treatment of recalcitrant keloids. Main outcomes are recurrence rate, scar quality and physical complaints.
- Trial name
- NCT02005055
- Testing
- Surgical excision with adjuvant high-dose-rate brachytherapy
- Where
- Netherlands
- Volunteers
- 43 people
- Sponsor
- Amsterdam UMC, location VUmc
Keloids, Fibroblast
Keloid Pathogenesis And Fibroblast Activation Study
Keloids are benign fibroproliferative skin disorders characterized by excessive fibroblast activation and extracellular matrix deposition. The molecular mechanisms underlying keloid formation remain incompletely understood.
- Trial name
- KPS (NCT07682636)
- Testing
- Tissue Collection
- Where
- China
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- The Fourth Affiliated Hospital of Zhejiang University School of Medicine
Keloid
A Study to Evaluate the Effectiveness and Safety of RXI-109 on the Outcome of Keloid Excision Surgery in Healthy Adults
To evaluate the effectiveness of RXI-109 in reducing the recurrence of keloid formation following elective keloid excision.
- Trial name
- NCT02079168
- Testing
- RXI-109
- Where
- 3 sites in United States, Dominican Republic
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- RXi Pharmaceuticals, Corp.
Keloid Scars, Hypertrophic Scars
Topical Cryotherapy and Keloid/Hypertrophic Scars
The goal of this clinical trial is to determine whether the application of brief topical cryotherapy immediately before intralesional corticosteroid injections can reduce pain and injection resistance during routine treatment of…
- Trial name
- NCT07336368
- Testing
- Cryotherapy with liquid nitrogen, Intralesional Triamcinolone 10 mg/ml
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Sonal Choudhary
Hypertrophic Scars, Keloids
Scars After Central Venous Catheters
Most children with cancer need a central venous catheter. These catheters are typically placed on the anterior thorax, where the risk of hypertrophic scarring and keloid development is greatly enhanced.
- Trial name
- NCT01113125
- Testing
- Betamethason-17-valerate and fusidic acid, Fusidic Acid
- Where
- Denmark
- Volunteers
- 60 people
- Sponsor
- Mette Møller Handrup
Keloid, Hypertrophic Scar
Comparison of the Efficacy of Different Steroids in the Treatment of Abnormal Scars (Keloids, Hypertrophic Scars)
Comparison of the Efficacy of Different Steroids in the Treatment of Abnormal Scars (Keloids and hypertrophic Scars)
- Conditions
- Keloid, Hypertrophic Scar, Scars, Scarring
- Trial name
- NCT04593706
- Testing
- Betamethasone acetate + Betamethasone sodium phosphate, Dexamethasone sodium phosphate, Methylprednisolone acetate
- Volunteers
- 40 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Keloid
Intralesional Cryosurgery Alone Versus Combined With 5-FU and Triamcinolone for Keloids
evaluate the efficacy and safety of intralesional cryosurgery alone compared with intralesional cryosurgery combined with intralesional 5-fluorouracil and triamcinolone acetonide in the treatment of keloids.
- Trial name
- NCT07526168
- Testing
- Intralesional Cryotherapy + Saline Injection, Intralesional Cryotherapy + TAC/5-FU Injection
- Volunteers
- 32 people
- Sponsor
- Assiut University
Scar, Hypertrophic
Intralesional Treatment of Keloids
Intralesional injection in treatment of keloid
- Trial name
- NCT06729840
- Testing
- Injection
- Where
- Egypt
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Sohag University