Clinical trials: Keratoconjunctivitis Sicca
Dry Eye Syndromes
Repeatability and Agreement of Anterior Segment Optical Coherence Tomography (AS-OCT) and Thermography
Dry eye is a common condition that affects vision and quality of life in patients. Dry eye clinical research is limited to follow up of disease progression.
- Trial name
- NCT01479790
- Testing
- EyeGiene
- Where
- Singapore
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Singapore National Eye Centre
Eye Disorders
Dry Eye in Upper Eyelid Surgery: Muscle Versus Fat Removal
The aim of this study is to compare the effects of two different surgical techniques (Orbicularis Oculi excision and Orbicularis Oculi + Fat excision) applied in upper blepharoplasty surgery on dry eye and to evaluate the effects…
- Trial name
- NCT06985264
- Testing
- Upper Eyelid Blepharoplasty surgery
- Where
- Turkey (Türkiye)
- Volunteers
- 142 people
- Sponsor
- Mersin Training and Research Hospital
All Diagnosed Health Conditions, ADD/ADHD
At-Home Research Study for Patients With Autoimmune, Inflammatory, Genetic, Hematological, Infectious, Neurological, CNS, Oncological, Respiratory, Metabolic Conditions
We are the missing link in clinical trials, connecting patients and researchers seamlessly and conveniently using a mobile health platform to advance medical research.
- Conditions
- All Diagnosed Health Conditions, ADD/ADHD, Alopecia Areata, Ankylosing Spondylitis
- Trial name
- NCT01931644
- Where
- United States
- Volunteers
- 17,667 people, healthy volunteers welcome
- Sponsor
- Sanguine Biosciences
Dry Eye Disease
Four-Week Ocular-Surface Evaluation of an Experimental Ophthalmic Liposomal Nanocarrier in Dry Eye Disease
This prospective, single-group research medical experiment evaluated the ocular-surface response to repeated bilateral use of an experimental ophthalmic liposomal nanocarrier in adults with dry eye disease.
- Trial name
- NCT07793344
- Testing
- Experimental ophthalmic liposomal nanocarrier
- Where
- Poland
- Volunteers
- 26 people
- Sponsor
- Regional Specialist Hospital in Wroclaw
Dry Eye Syndromes
Comparison Of Blue Light Filter Feature and Blue Blocking Lenses in Digital Device Users With Dry Eye Patients
Comparing Blue Light Filter feature and Blue Blocking Lenses for Dry Eye Patients Prolonged screen time can exacerbate dry eye symptoms.
- Trial name
- NCT06913504
- Testing
- Blue cut filter, blue cut glasses
- Where
- Pakistan
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Superior University
Dry Eye Syndromes
Local Tolerability of Chitosan-N-acetylcysteine Eye Drops in Healthy Young Volunteers
The "dry eye syndrome" DES is a highly prevalent ocular disease, in particular in the elderly population. One mainstay of therapy for patients suffering from DES is the use of topically administered lubricants.
- Trial name
- NCT01278784
- Testing
- 0.05% Chitosan-N-Acetylcysteine eye drops, 0.1% Chitosan-N-Acetylcysteine eye drops
- Where
- Austria
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Dry Eye
Phase 1 Study for Safety and Tolerability of EBI-005 Topically Administered to Eyes of Healthy Adult Subjects
This is a First-In-Human (FIH) study to assess the safety and tolerability of ocular administration of EBI-005 in healthy volunteers. Additionally, the PK and immunogenicity of EBI-005 will be assessed.
- Trial name
- EBI-005-1 (NCT01748578)
- Testing
- EBI-005-1
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Eleven Biotherapeutics
Dry Eye
Investigator Initiated Study to Assess the Efficacy of OC-01 (Varenicline) Nasal Spray on Signs and Symptoms of Dry Eye Disease Following Photorefractive Keratectomy (PRK)
Evaluate the safety and effectiveness of OC-01 (varenicline) nasal spray among subjects suffering from dry eye following photorefractive keratectomy (PRK)
- Trial name
- NCT05045508
- Testing
- OC-01 (varenicline 0.6mg/ml) nasal spray
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Brandon Baartman
Dry Eye
The Effect of 0.05% CsA Eye Drops on Post-refractive Surgery Dry Eye
The purpose of this study is to observe the effect of 0.05% cyclosporine eyedrops combined with artificial tears in patients with dry eyes after corneal refractive surgery and to observe the changes in ocular surface…
- Trial name
- NCT06043908
- Testing
- artificial tear eyedrops, 0.05% cyclosporine eyedrops
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Peking University Third Hospital
Dry Eye Disease (DED)
Clinical Study Aimed At Evaluating the Safety and Efficacy of Tear Substitute Formulations in the Treatment of Dry Eye Disease.
This clinical study is aimed at evaluating the safety and effectiveness of 2 test formulations (Rain and Mist), against an approved over-the-counter formulation (Systane Ultra) and a placebo (saline), in the treatment of moderate…
- Trial name
- NCT06633471
- Where
- Barbados
- Volunteers
- 175 people
- Sponsor
- PS Therapy Inc.
Sjogren's Syndrome, Digestive System Abnormalities
Evaluation of the Prevalence of Functional Digestive Disorders During Primary Sjögren Gougerot Syndrome
the investigators propose to carry out a prospective study consisting of a systematic research of digestive symptoms in patients with SGSp with the validated Global symptom score (GSS) questionnaire, which allowed to grades…
- Trial name
- GASTRO-SGS (NCT03157011)
- Testing
- Global symptom score (GSS) questionary
- Where
- France
- Volunteers
- 151 people
- Sponsor
- University Hospital, Limoges
Dry Eye
Effect of Periorbital Massage on Dry Eye Disease
This randomized controlled trial aims to investigate the efficacy of periorbital massage therapy in alleviating symptoms and improving clinical outcomes in patients diagnosed with dry eye disease.
- Trial name
- NCT06390644
- Testing
- Periorbital Massage Therapy, Control Group (Standard Care)
- Where
- Pakistan
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Superior University
Dry Eye
Phase 2b Controlled Study of Dosing Techniques - Part B
Double-masked, dose-response of two concentrations of IVW-1001
- Trial name
- NCT07161011
- Testing
- IVW-1001 Ophthalmic Eyelid Wipe 0.2%, IVW-1001 Ophthalmic Eyelid Wipe 0.4%
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- IVIEW Therapeutics Inc.
Dry Eye
An Open Label Comparing the Short Term Efficacy of Lacrisert
To evaluate the short term effects of LACRISERT®. upon fluorescein corneal staining, tear osmolarity and surface topography in human subjects with dry eye disease.
- Trial name
- NCT03079271
- Testing
- Lacrisert, 5 Mg Ophthalmic Insert
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Virginia Eye Consultants
Inflammation, Sjogren's Syndrome
Superb Microvascular Imaging Ultrasonography of Lacrimal Gland in Patients With Sjögren Syndrome
A prospective study will be conducted to evaluate inflammatory activity in lacrimal glands due to Sjögren's syndrome on Superb Microvascular Imaging (SMI), gray scale ultrasound (US), color Doppler US and Power Doppler US.
- Conditions
- Inflammation, Sjogren's Syndrome, Gland; Inflammation
- Trial name
- SMI (NCT05689749)
- Testing
- Superb Microvascular Imaging (SMI) (Toshiba)
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Nigde Omer Halisdemir University
Dry Eye Disease
Examining the Clinical Characteristics, Treatment Patterns, Real-world Effectiveness, and Healthcare Resource Utilization of Patients With Dry Eye Disease
A prospective, non- interventional, observational, non-comparative, longitudinal cohort study design will be used to address the objectives of this study using data collected through a healthcare.
- Trial name
- NCT05857748
- Testing
- lifitegrast
- Sponsor
- Novartis Pharmaceuticals
Primary Immune Thrombocytopenia, Sjögren's Syndrome
Managed Access Programs for VAY736, Ianalumab
The purpose of this registration is to list Managed Access Programs (MAPs) related to VAY736, ianalumab
- Trial name
- NCT07244289
- Testing
- ianalumab
- Sponsor
- Novartis Pharmaceuticals
Dry Eye Syndromes
Acupuncture for Dry Eye Syndrome
This study is about the effectiveness of acupuncture treatment on dry eye syndrome. Study hypothesis is that a standardized acupuncture would be more effective than a sham acupuncture in dry eye syndrome patients.
- Trial name
- NCT00969280
- Testing
- Standardized Acupuncture, Non-acupuncture point shallow penetration acupuncture
- Where
- South Korea
- Volunteers
- 42 people
- Sponsor
- Korea Institute of Oriental Medicine
Dry Eye
Laser Acupuncture for Dry Eye
Subjects with dry eye are enrolled at two ophthalmic centers and randomly assigned to a laser acupuncture group and control group under conventional treatment with artificial tears.
- Trial name
- NCT03204903
- Testing
- Laser acupuncture
- Where
- Taiwan
- Volunteers
- 200 people
- Sponsor
- Chang Gung Memorial Hospital
Sjogren's Syndrome
The Functioning of Immune and Hormonal Systems in Patients With Sjogren's Syndrome and in Healthy Volunteers
This study aims to learn more about how the immune and hormonal systems function in patients with Sjogren's syndrome, a disease in which the immune system does not function properly.
- Trial name
- NCT00001953
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- National Institute of Dental and Craniofacial Research (NIDCR)