Clinical trials: Ketogenic Diet
Insulin Resistance
Study of Keto Acid (KA) on Insulin Resistance in Peritoneal Dialysis (PD) Patients
The overarching aim of this proposal is to examine the effects of usual protein diet supplemented with keto acid (KA) on insulin sensitivity in patients on peritoneal dialysis (PD).
- Trial name
- NCT01496092
- Testing
- Keto Acid
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Peking University First Hospital
Traumatic Brain Injury, Ketogenic Dieting
Ketogenic Diet for Traumatic Brain Injury
Traumatic Brain Injury is a major health concern in United States. There is a un-met need to develop new therapeutic options for faster neuron recovery without causing significant side effects.
- Trial name
- KETI (NCT03982602)
- Testing
- Ketogenic diet
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of Missouri-Columbia
Diabetes Mellitus, Type 1
The Effects of a Low Carbohydrate, Non-Ketogenic Diet Versus Standard Diabetes Diet on Glycemic Control in Type 1 Diabetes
This randomized, crossover nutrition intervention seeks to examine the effects of a non-ketogenic low carbohydrate (CHO) diet (60-80g per day) on glycemic control, lipids, and markers on inflammation in individuals with Type 1…
- Trial name
- T1DLoCHO (NCT03544892)
- Testing
- Low carbohydrate diet, Standard of care diet
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- University of Oklahoma
Epilepsy, Dyslipidemia
Improving Cardiovascular Health Risks in Adults With Epilepsy on a Modified Atkins Diet
Ketogenic diet therapies (KDTs) emphasize high fat and very low carbohydrate intake and help to control seizures in adults who fail to respond to medications.
- Trial name
- NCT06369571
- Testing
- Atorvastatin 10mg, Modification of dietary fat composition
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Johns Hopkins University
Type 2 Diabetes, PreDiabetes
Ketogenic Diet and Diabetes Demonstration Project
KDDP is a prospective, 12-month pilot study comparing the effects of a novel lifestyle program, the Ketogenic Diet and Diabetes Demonstration Project (KDDP) to those of the National Diabetes Prevention Program (NDDP).
- Conditions
- Type 2 Diabetes, PreDiabetes, Obesity, Ketogenic Dieting
- Trial name
- KDDP (NCT06115265)
- Testing
- Ketogenic diet, Low Fat diet
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of New Mexico
Cardiac Sarcoidosis
Diagnostic Utility of SGLT1/2 Inhibition to Facilitate Myocardial Glucose Suppression
This is a pilot mechanistic study of the diagnostic utility of sodium-glucose cotransporter-1/2 inhibition (SGLT1/2) on myocardial glucose suppression on FDG PET/CT.
- Trial name
- NCT06510894
- Testing
- Sotagliflozin
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Neoplasms
Impact of a Ketogenic Diet Intervention During Radiotherapy on Body Composition
Type of study: Pilot / phase I trial Study purpose To assess the impact of a dietary intervention during radio(chemo)therapy (RCT) on body composition changes Trial Treatment Patients will be split into a control group and…
- Trial name
- KETOCOMP (NCT02516501)
- Testing
- MyAmino, betaquik, Radio(chemo)therapy
- Where
- Germany
- Volunteers
- 156 people
- Sponsor
- MVZ Leopoldina GmbH
Parkinson Disease
Effects of Exercise Training and Ketone Ester on Muscle Strength and Cardiovascular Response in Parkinson's Disease
The main purpose of this study is to assess changes in exercise capacity in people with Parkinson's disease before and after an exercise training program with ketone ester supplementation.
- Trial name
- CYCLE (NCT05948956)
- Testing
- Ketone Ester Beverage, Electrolyte Beverage, Cycling Intervention
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- University of Michigan
Ketogenic Dieting, Physical Activity
Effects of Ketogenic Diet on Triathlon's Performance
The study aimed to verify the effects of 5 weeks of ketogenic diet (KD) on some performance index in long distance triathletes
- Trial name
- NCT03691558
- Testing
- Ketogenic diet, Western Diet
- Where
- Italy
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Padova
Chronic Obstructive Pulmonary Disease (COPD)
Ketogenic Dietary Intervention in Men With Mild-to-Moderate COPD
Chronic obstructive pulmonary disease (COPD) is associated with persistent airflow limitation, systemic inflammation, reduced exercise capacity, and unfavorable changes in body composition.
- Trial name
- COPDKETO (NCT07664111)
- Testing
- Ketogenic diet, Standard Dietary Advice
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people
- Sponsor
- Agri Ibrahim Cecen University
Epilepsy, Drug Resistant Epilepsy
Ketonemia Through Menstrual Cycle
Ketogenic dietary therapies (KDTs) are well-established, safe, non-pharmacologic treatments used for children and adults with drug-resistant epilepsy and other neurological disorders.
- Conditions
- Epilepsy, Drug Resistant Epilepsy, GLUT1DS1, Ketogenic Dieting
- Trial name
- KETOMENS (NCT05234411)
- Testing
- Evaluation of ketogenic diet impact on ketonemia
- Where
- Italy
- Volunteers
- 15 people
- Sponsor
- University of Pavia
Polycystic Ovary Disease
"KETOGENIC MEDITERRANEAN VERSUS HYPOCALORIC BALANCED DIET ON POLYCYSTIC OVARIAN ADOLESCENTS"
study was designed to determine the effect of ketogenic Mediterranean diet versus hypocaloric balanced diet on adolescent female with polycystic ovary disease.
- Trial name
- keto- MEDITERR (NCT06610812)
- Testing
- KETOGENIC MEDITERRANEAN diet, hypo-caloric diet:, moderate aerobic exercises
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- MTI University
Obesity
Impact of Ketogenic Diets in Preventing Relapse in Obesity Management
Low-carb ketogenic diets have become extremely popular because of large weight loss in the short-term. Yet their potential benefits in preventing long-term weight regain have not been assessed in large scale studies.
- Trial name
- Ketomaintain (NCT04382183)
- Testing
- Ketogenic weight loss maintenance diet, Isocaloric balanced weight loss maintenance diet
- Where
- Norway
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Norwegian University of Science and Technology
Brain, Cancer
A Ketogenic Diet as a Complementary Treatment on Patients With High-grade Gliomas and Brain Metastases
The survival interval of patients with gliomas ranges between 12 to 15 months. Recent findings revealed that dietary interventions to reduce glucose and glycolytic pathways could have a therapeutic effect.
- Trial name
- NCT05564949
- Testing
- CKD
- Where
- 2 sites in Greece
- Volunteers
- 15 people
- Sponsor
- Attikon Hospital
Heart Failure
Reverse HFpEF: Ketogenic Reversal of Heart Failure With Preserved Ejection Fraction Study
This protocol is a prospective pilot study utilizing the intervention of a medically supervised, registered nurse and registered diabetes educator coached low-carbohydrate, ketogenic diet to examine the impact it has as a…
- Trial name
- NCT04942548
- Testing
- Ketogenic Diet
- Where
- 2 sites in United States
- Volunteers
- 16 people
- Sponsor
- National Jewish Health
Glioblastoma Multiforme
Ketogenic Diet Adjunctive to Salvage Chemotherapy for Recurrent Glioblastoma:a Pilot Study
Recently, ketogenic diet has been recognized a useful treatment strategy for glioblastoma in vitro. Therefore, the purpose of the study is to evaluate the safety and efficacy of ketogenic adjuvant to salvage chemotherapy for…
- Trial name
- KGDinrGBM (NCT02939378)
- Testing
- Ketogenic diet, Standard diet
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Song Lin
Metabolic Syndrome
Optimal Metabolic Health Through Continuous Glucose Monitoring
The primary focus of this study is to evaluate the role of Continuous Glucose Monitoring (CGM) with Levels Health software as a tool to provide feedback and accountability necessary to create sustainable behavioral changes in…
- Trial name
- CGM (NCT04920058)
- Testing
- Continuous Glucose Monitor, <Active Comparator?>
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Overweight, Obesity
The Effect of the Treatment Program "Dr. Fedon Lindbergs Vektcoach" on Body Weight and Composition and Hormonal Profile
The background for the trial is a number of previous studies indicating that it is especially important to restrict the intake of carbohydrates when treating overweight and metabolic diseases in general.
- Conditions
- Overweight, Obesity, Metabolic Syndrome
- Trial name
- NCT01235208
- Testing
- The "Dr. Fedon Lindbergs Vektcoach" Treatment
- Where
- Norway
- Volunteers
- 44 people
- Sponsor
- Eurodiet Scandinavia AS
Ketogenic Dieting
Determining the Ergogenic Effects of Carb10™ Supplementation on Carbohydrate-Rich and Carbohydrate-Restricted Diets
The study will examine the performance and body composition effects of ketogenic vs carbohydrate-based diets, determine the carbohydrate tolerance ("carbohydrate threshold") for active individuals on a ketogenic diet, and then…
- Trial name
- NCT03231514
- Testing
- Carbohydrate Supplement (Carb10), Diet, Exercise
- Where
- United States
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Texas Woman's University
GLUT1DS1
Compatibility of C7 With Ketogenic Diet in Patients Diagnosed With G1D
To explore triheptanoin (C7 oil) compatibility with the ketogenic diet by evaluating EEG, and seizure rate, glycemia and ketosis in proven G1D patients receiving a ketogenic diet.
- Trial name
- NCT03301532
- Testing
- Triheptanoin
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Texas Southwestern Medical Center