Clinical trials: Ketones
E04.525.190, Craniotomy
Case Series to Evaluate Patient Specific Implants (PSI) in Polyether Ether Ketone (PEEK) Performance After 2 Years
The primary objective of this retrospective study is to evaluate the percentage of patients with device related adverse events (infection, rejection, dislocation, fracture of the implant) in the first 24 months after implantation.
- Conditions
- E04.525.190, Craniotomy, Craniectomy
- Trial name
- NCT01282645
- Testing
- PSI in PEEK
- Where
- 30 sites in Austria, Belgium and 13 more
- Sponsor
- Synthes GmbH
Fasting
Effects of Fast Bar on Physiological Fasting
This study evaluates how Fast Bar(TM), a specially formulated energy bar, affects the physiological condition in participants after an overnight fasting.
- Trial name
- FastBar (NCT04499599)
- Testing
- Dinner, Fasting, Study food
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- L-Nutra Inc
Ketogenic Dieting, Ketosis
Characterization of a Portable Solid-State Breath Acetone Testing Device for Real-Time Ketosis Status
The primary purpose of this study is to characterize the performance and utility of a novel breath acetone meter developed by Readout, Inc.
- Trial name
- NCT04130724
- Testing
- Blood ketone testing, Breath ketone testing
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Readout, Inc.
Healthy
Study to Compare the Pharmacokinetics of AC 1202 and Two Doses of AC-SD-01 on Ketone Body Production
To compare serum ketone body (i.e., total ketones, β hydroxybutyrate, and estimate of acetoacetate) levels after single dose administration of AC-1202 and 2 doses of AC-SD-01.
- Trial name
- NCT03063645
- Testing
- AC-1202, AC-SD-01 (50 g), AC-SD-01 (75 g)
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Cerecin
Diabetes
Method Comparison/User Evaluation of the i-SENS Self-Monitoring Blood Glucose / β-Ketone System
The goal of this clinical trial is to assess the accuracy and usability of the blood glucose meter in untrained participants, both with or without diabetes, as well as those with pre-diabetes.
- Trial name
- NCT05833100
- Testing
- CareSens PRO GK Blood Glucose/b-Ketone Monitoring system
- Where
- United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- i-SENS, Inc.
Healthy
Evaluation of PK of Caprylic Triglyceride Oil, AC-1202, AC-1204, and Axona on Ketone Body Production
To compare serum ketone body (i.e., total ketones, β hydroxybutyrate, and estimate of acetoacetate) levels after single dose administration of caprylic triglyceride (CT) oil, AC-1202, AC-1204, and Axona®.
- Trial name
- NCT02833012
- Testing
- Caprylic Triglyceride Oil, AC-1202, Axona
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cerecin
Healthy Men and Women
Ketone Plasma Kinetics After Oral Intake of Different Ketogenic Formulae
This research project aims at evaluating the effect of various ketone precursors and their formulations on blood ketone level after oral intake. Evaluation of the GI tolerability of the various formula will be also evaluated.
- Trial name
- NCT05058157
- Testing
- different ketogenic formulae
- Where
- Switzerland
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Société des Produits Nestlé (SPN)
Healthy Volunteer
Comparison of Pharmacokinetic Responses to Three Ketone Esters
The purpose of this study is to examine how the body absorbs, digests, and metabolizes three different investigational ketone dietary supplements (ketone monoester, ketone tri-ester, ketone salt) and to assess gastrointestinal…
- Trial name
- NCT07289165
- Testing
- Dietary Supplement containing Tri-betahydroxybutyrin, Dietary Supplement containing a ketone mono Ester, Dietary supplement containing a ketone salt
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- NeuroEnergy Ventures, Inc.
Migraine Headache
Ketone for Migraine Prevention
Efficacy of a nutritional ketogenic supplement (NKS) in reducing the number, intensity, and duration of migraine headaches in episodic migraine patients.
- Trial name
- NCT05085483
- Testing
- Nutritional Ketogenic Supplement
- Where
- Canada
- Volunteers
- 54 people
- Sponsor
- Société des Produits Nestlé (SPN)
Alzheimer's Disease
Tricaprilin in Mild to Moderate Alzheimer's Disease
The purpose of this study is to evaluate the safety, tolerability and effectiveness of tricaprilin administered once a day for ninety days in subjects with mild to moderate, probable Alzheimer's disease.
- Trial name
- NCT00142805
- Testing
- Tricaprilin
- Where
- 25 sites in United States
- Volunteers
- 152 people
- Sponsor
- Cerecin
Pharmacokinetics
Pharmacokinetics of Two Fatty Acid Ketone Esters
Randomized, cross over pharmacokinetic study of a novel ketone di-ester and C6 ketone di-ester in ready to drink beverage matrices.
- Trial name
- NCT05686083
- Testing
- C6 ketone di-ester, Novel ketone di-ester
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- BHB Therapeutics, Ireland LTD