Clinical trials: Ketorolac
Pain, Postoperative, Phimosis
Evaluating Pain Outcomes of Ketorolac Administration in Children Undergoing Circumcision
Circumcision is the most common surgical procedure performed by Pediatric Urologists. Ketorolac has been shown to have an efficacy similar to morphine in multi-modal analgesic regimens without the commonly associated adverse…
- Conditions
- Pain, Postoperative, Phimosis, Paraphimosis, Balanitis
- Trial name
- NCT02973958
- Testing
- Bupivacaine, Sevoflurane, Acetaminophen
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Alberta Children's Hospital
Osteoarthritis, Tendinopathy
Ketorolac in Upper Extremity Tendinopathy and Arthropathy
Osteoarthritis (OA) and inflammatory conditions of the tendons and joints of the shoulder, elbow, hand, and wrist are common yet disabling diseases.
- Conditions
- Osteoarthritis, Tendinopathy, Arthropathy
- Trial name
- NCT05292339
- Testing
- Triamcinolone injection to the shoulder, elbow, wrist, or hand, Ketorolac injection to the shoulder, elbow, wrist, or hand
- Where
- 4 sites in United States
- Volunteers
- 160 people
- Sponsor
- Emory University
Pain, Postoperative
Study Evaluating the Effects of Toradol and Lyrica for Pain Control After Donor Nephrectomy
The investigators will assess how the use of toradol and pregabalin affects return to bowel function and see if there is a difference in length of hospital stay.
- Trial name
- NCT03669081
- Testing
- Ketorolac, Pregabalin, Saline
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- University of Utah
Subacromial Impingement, Subacromial Impingement Syndrome
Subacromial Methylprednisolone Versus Ketorolac for Shoulder Impingement
The investigators aim to compare subacromial ketorolac (non-steroidal anti-inflammatory drug) versus methylprednisolone (steroid) for the treatment of shoulder impingement syndrome.
- Trial name
- NCT03913702
- Testing
- Ketorolac Tromethamine, Methylprednisolone Acetate
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- The University of Texas Medical Branch, Galveston
Acute Renal Colic
Atomized Intranasal Vs Intravenous Ketorolac in Acute Renal Colic Pain Management.
Introduction: Pain is a common reason for individuals to seek health care, especially emergency care. Ketorolac has numerous advantages over other pain medications, especially the opioids.
- Trial name
- Ink-Arc (NCT04441762)
- Testing
- Intravenous Ketorolac Tromethamine, Intranasal Ketorolac Tromethamine
- Where
- Oman
- Volunteers
- 171 people
- Sponsor
- Oman Medical Speciality Board
Sickle Cell Disease, Sickle Cell Crisis
Ketorolac for Acute Vaso-Occlusive Crisis in Pediatric Sickle Cell Disease
Pediatric patients who present with acute vaso-occlusive pain crisis may have equivalent pain reduction scores at lower dosing of intravenous Ketorolac compared to standard dosing of 0.5 mg/kg/dose IV (<16yo max 15mg, >16yo max…
- Conditions
- Sickle Cell Disease, Sickle Cell Crisis, Veno-occlusive Disease
- Trial name
- NCT06579703
- Testing
- Ketorolac
- Volunteers
- 102 people
- Sponsor
- Children's Blood and Cancer Center at Dell Children's Medical Center
Wet Macular Degeneration
Pilot Study of Ranibizumab With and Without Ketorolac Eyedrops for Exudative Age-related Macular Degeneration
The addition of an anti-inflammatory agent could be a valid option for controlling choroidal neovascularization, as simply inhibiting VEGF addresses neither the multifactorial pathogenesis of choroidal neovascularization nor the…
- Trial name
- NCT02060604
- Testing
- Ketorolac + Ranibizumab, Ranibizumab
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- Università degli Studi di Brescia
Cataract
Ketorolac Levels in Vitreous and Aqueous Samples From Patients Undergoing Combined Cataract and Pars Plana Vitrectomy Surgeries With and Without Intracameral Phenylephrine 1.0% / Ketorolac 0.3%
This is a clinical trial evaluating Ketorolac levels in vitreous and aqueous humor samples from patients undergoing combined cataract and pars plana vitrectomy surgeries with and without intracameral phenylephrine 1.0% /…
- Trial name
- NCT06539637
- Testing
- OMIDRIA (*Registered Product) {10.16 mg/mL (1% w/v) of phenylephrine and 2.88 mg/mL (0.3% w/v) of ketorolac}, Ketorolac Tromethamine {TORADOL} (0.5%) - Topical Eyedrop
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- DHS Consulting
Postoperative Pain
Safety and Efficacy of Multiple Doses of Ketorolac Tromethamine Administered Intranasally for Postoperative Pain
This was a randomized, double-blind, placebo-controlled study in subjects who underwent major surgery. Each subject's study participation consisted of a screening visit and a treatment period of up to 5 days.
- Trial name
- NCT01347853
- Testing
- Ketorolac tromethamine
- Where
- New Zealand
- Volunteers
- 300 people
- Sponsor
- Egalet Ltd
Renal Colic
Morphine Versus Ketorolac in Renal Colic
The study is prospective, double blinded, randomised controlled and has the purpose to compare the analgesic effects of ketorolac or morphine intravenous in renal colic.
- Trial name
- NCT02782273
- Testing
- Ketorolac, Morphine
- Volunteers
- 100 people
- Sponsor
- Loredana Ghinea
Chronic Periodontitis
Teh Effect of Subgingival Irrigation Wif Ketorolac and Chlorhexidine in Patients Wif Chronic Periodontist
In this study, 40 patients with a history of Mild- Periodontitis who were diagnosed with clinical and radiographic findings showed that all of the periodontal parameters before the treatment, during the treatment period Then…
- Trial name
- NCT03836781
- Testing
- Ketorolac, Chlorhexidine 2%
- Where
- Iran
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Amirhossein Farahmand
Renal Calculus, Kidney Stones
Intravenous Ketorolac for Postoperative Pain in Percutaneous Nephrolithotomy
The purpose of this study is to determine whether continuous intravenous ketorolac infusion reduces pain in patients who are having percutaneous nephrolithotomy for kidney stone disease.
- Trial name
- NCT00765128
- Testing
- Ketorolac
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Mayo Clinic
Surgery, Upper Extremity
Pain Control With Ketorolac and Nerve Block After Wrist and Hand Surgery
The purpose of this study is to learn about the effectiveness of different pain control options after hand and wrist surgery, specifically Ketorolac, Tylenol, and a regional nerve block.
- Trial name
- NCT07773155
- Testing
- Toradol, Oxycodone
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- University of Chicago
Postoperative Pain
Intravenous Dexmedetomidin on Postoperative Pain After Hypospadias Repair in Children
This study aimed to evaluate the efficacy of intravenous ketorolac versus dexmedetomidine as analgesia after Hypospadias repair surgery to determine the optimal procedure for pain control and postoperative reduction of analgesic…
- Trial name
- NCT05194904
- Testing
- Dexmedetomidine
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Assiut University
Breast Cancer Female
Ketorolac for Analgesia followiNG Autologous Breast RecOnstructiOn
Background: Ketorolac tromethamine is a nonsteroidal anti-inflammatory drug that has been shown to reduce breakthrough narcotic consumption following orthopaedic, neurosurgical, and obstetrical procedures.
- Trial name
- KANGAROO (NCT03007381)
- Testing
- Ketorolac Tromethamine, Normal Saline
- Sponsor
- Nova Scotia Health Authority
Kidney Calculi, Ureteral Calculi
Study of Ketorolac Versus Opioid for Pain After Endoscopy
A double blind randomized controlled trial designed to compare pain control and safety with ketorolac and oxycodone in the post-operative setting for patients undergoing ureteroscopy for treatment of urinary stones.
- Trial name
- SKOPE (NCT03888144)
- Testing
- Oxycodone, Ketorolac
- Where
- United States
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Analgesia, Obstetrical, Coagulation Defect; Postpartum
IV Ketorolac on Platelet Function Post-Cesarean Delivery
Cesarean delivery has become the most common surgical procedure in the US. Non-steroidal anti-inflammatory drugs (NSAIDs) have been shown to improve the quality of post-cesarean analgesia and markedly reduce opioid consumption.
- Conditions
- Analgesia, Obstetrical, Coagulation Defect; Postpartum, Nonsteroidals (NSAIDs)Toxicity, Postpartum Hemorrhage
- Trial name
- KetoPltAgg (NCT03805607)
- Testing
- Ketorolac Tromethamine 30 MG/ML
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
Adhesive Capsulitis of the Shoulder
Intra-articular Corticosteroids Are Widely Used for Adhesive Capsulitis, But Alternatives Are Required for Patients With Contraindications. Hyaluronic Acid (HA) and Ketorolac Have Shown Individual Benefits. However, Evidence on Their Combination Remains Limited.
This randomized, double-blind trial compared a single intra-articular injection of moderate-molecular-weight hyaluronic acid (HA) plus ketorolac with ketorolac alone in patients with adhesive capsulitis.
- Trial name
- NCT07183436
- Testing
- Intra-articular Hyaluronic Acid and Ketorolac, Intra-articular Ketorolac
- Where
- Thailand
- Volunteers
- 56 people
- Sponsor
- Mahidol University
Pain Management, Abortion
Paracervical Block With Combined Ketorolac and Lidocaine for Osmotic Dilator Placement
The purpose of this study is to improve pain management for participantswho need osmotic dilators for cervical preparation the day before their second trimester abortion procedure.
- Conditions
- Pain Management, Abortion, Second Trimester Abortion, Dilation and Evacuation
- Trial name
- PCB-KinD (NCT07487246)
- Testing
- Ketorolac, oral ibuprofen, Lidocaine HCl 1%
- Where
- United States
- Volunteers
- 76 people
- Sponsor
- Rush University Medical Center
Infertility, Female
Ibuprofen Versus Ketorolac for Pain Relief During Hysterosalpingogram
Hysterosalpingogram (HSG) testing is a vital part of the workup for infertility patients. It is often noted to be biggest pain that patients undergo during the workup.
- Trial name
- NCT05190341
- Testing
- Ibuprofen 800 mg oral, Ketorolac 30mg oral
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Madigan Army Medical Center