Clinical trials: Kidney; Disease, Acute
Acute Kidney Injury
TIMP-2 and IGFBP7 for the Prediction of the Cardiac Surgery Associated Acute Kidney Injury
The purpose of this study is to analyze the new biomarkers (TIMP-2 and IGFBP-7) of tubular renal cell damage for the prediction of the Cardiac Surgery Associated acute kidney injury.
- Trial name
- NCT02054546
- Where
- Switzerland
- Volunteers
- 110 people
- Sponsor
- University Hospital, Basel, Switzerland
Acute-on-Chronic Liver Failure (ACLF)
Vitamin C for Acute Kidney Injury in ACLF With Septic Shock: A Randomized Controlled Trial
This study is testing whether Vitamin C can help improve kidney function and survival in very sick patients with liver disease. Patients with acute-on-chronic liver failure (ACLF) often develop serious infections that can lead to…
- Trial name
- VITAKI-ACLF (NCT07184866)
- Testing
- Vitamin C, Standard of Care (SOC)
- Volunteers
- 110 people
- Sponsor
- Institute of Liver and Biliary Sciences, India
Critical Illness, Acute Kidney Injury
Balanced Solution Versus Saline in Intensive Care Study
A 2x2 factorial randomized study to evaluate the effect of a balanced crystalloid solution compared with 0.9% saline, and of rapid vs. slow infusion on clinical outcomes of critically ill patients
- Trial name
- BaSICS (NCT02875873)
- Testing
- Plasma-Lyte, Saline 0.9%, Slow infusion speed
- Where
- Brazil
- Volunteers
- 11,075 people
- Sponsor
- Hospital do Coracao
Renal Insufficiency, Acute
NIRS for the Diagnosis and Prevention of Acute Renal Failure
This prospective study will take place at Hotel Dieu de France hospital in Lebanon. One hundred children undergoing cardiac surgery for congenital heart disease between May 2020 and May 2021 will be included.
- Trial name
- NCT04605705
- Testing
- Optimization of the cardiac output, the temperature, the hemoglobin in order to have the NIRS value by up to 80%.
- Where
- Lebanon
- Volunteers
- 100 people
- Sponsor
- Saint-Joseph University
End Stage Liver DIsease, Liver Transplant; Complications
Intraoperative Normal Saline Administration and Acute Kidney Injury in Patients Undergoing Liver Transplantation
The investigators attempted to investigate the association of the type of crystalloid administered during liver transplantation with postoperative clinical outcomes.
- Conditions
- End Stage Liver DIsease, Liver Transplant; Complications, Liver Cirrhosis
- Trial name
- NCT05386953
- Testing
- Normal saline, Balanced crystalloid solution
- Where
- South Korea
- Volunteers
- 1,440 people
- Sponsor
- Seoul National University Hospital
Acute Kidney Injury, Drug Use
A Big Data Approach to Predict NEOnatal Acute Kidney Injury in Newborns expoSed to nephroTOxic Drugs (NeoAKI STOP)
This observational retrospective study aims to learn about the incidence of acute kidney (AKI) injury in newborns in infants exposed to nephrotoxic drugs with a big data approach.
- Conditions
- Acute Kidney Injury, Drug Use, Drug Interaction, Drug Toxicity
- Trial name
- NeoAKISTOP (NCT05851222)
- Where
- Italy
- Volunteers
- 4,200 people
- Sponsor
- Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Chronic Myeloproliferative Disorders, Leukemia
506U78 in Treating Patients With Hematologic Cancer and Kidney or Liver Impairment
RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. PURPOSE: Phase I trial to study the effectiveness of 506U78 in treating patients who have hematologic cancer…
- Conditions
- Chronic Myeloproliferative Disorders, Leukemia, Lymphoma, Multiple Myeloma and Plasma Cell Neoplasm
- Trial name
- NCT00004239
- Testing
- Compound 506U78
- Where
- 3 sites in United States
- Volunteers
- 10 people
- Sponsor
- Alliance for Clinical Trials in Oncology
Acute Myeloid Leukemia, Myelodysplasia
Non-Myeloablative Allogeneic Stem Cell Transplantation With Matched Unrelated Donors for Treatment of Hematologic Malignancies, Renal Cell Carcinoma, and Aplastic Anemia
The primary objective of this study is to examine transplant related mortality (TRM) at 100 days <30%. A TRM of >50% is considered unacceptable.
- Conditions
- Acute Myeloid Leukemia, Myelodysplasia, Acute Lymphoblastic Leukemia, Chronic Lymphocytic Leukemia
- Trial name
- NCT00513175
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- University of California, San Francisco
Acute Kidney Injury
Renal Angina Index for Predicting Acute Kidney Injury in Adult ICU Patients
Acute kidney injury (AKI) is a frequent complication of critical illness and is associated with increased morbidity and mortality.
- Trial name
- NCT07863505
- Testing
- Renal Angina Index Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 324 people
- Sponsor
- Izmir Katip Celebi University
Lumbar Fusion Surgery, Elderly Patients
Clinical Impact of Different Crystalloid Solution on Early Biomarkers of Kidney Injury After Lumbar Fusion Surgery in Elderly Patients
This study aims to compare the effects of sodium acetate Ringer's solution versus sodium lactate Ringer's solution on early postoperative renal function indicators, renal injury biomarkers, and acute kidney injury (AKI) in…
- Conditions
- Lumbar Fusion Surgery, Elderly Patients, Sodium Acetate Ringer's Solution, Sodium Lactate Ringer's Solution
- Trial name
- NCT07542353
- Testing
- Sodium Acetate Ringer's Solution (Group A), Sodium Lactate Ringer's Solution (Group B)
- Where
- China
- Volunteers
- 174 people
- Sponsor
- Xianping Wu
Septic Shock
Severe Septic Shock Complications
Adults older than 18 years old, admitted to the ICU with a Severe Septic Shock, requiring Norepinephrine at more than 0.25mcg/kg/min, who have signed informed consent form, will be consecutively included, from december 2018 to…
- Trial name
- NCT03716895
- Where
- Spain
- Volunteers
- 300 people
- Sponsor
- Institut d'Investigació Biomèdica de Girona Dr. Josep Trueta
Critical Illness, Ventilation
Wise Choices in the Intensive Care Unit
Aim: to evaluate if the Choosing Wisely campaign can be introduced without harming critically ill patients. Background: Each year, around 45,000 patients are admitted to Sweden's 81 ICUs (intensive care units), costing 6-7…
- Conditions
- Critical Illness, Ventilation, Outcome, Dialysis
- Trial name
- WICH-ICU (NCT07013175)
- Testing
- Choosing wisely protocol
- Where
- 2 sites in Sweden
- Volunteers
- 10,000 people
- Sponsor
- Karolinska Institutet
Intraoperative Hypotension
Hypotension Prediction Index and Intraoperative Hypotension Incidence
This study aim to implement intraoperative hemodynamic monitoring and management guided with HPI algorithm in frail patients undergoing elective abdominal surgery.
- Trial name
- NCT06909786
- Testing
- HPI guided hemodynamic management, standard arterial line
- Where
- China
- Volunteers
- 100 people
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University
Infections, Urinary Tract
GSK2251052 in Complicated Urinary Tract Infection
This study is being conducted to evaluate the safety, efficacy (clinical and microbiological), pharmacokinetics/pharmacodynamics of GSK2251052 and to assess whether it would be a suitable antibiotic for the treatment for febrile…
- Trial name
- NCT01381549
- Testing
- GSK2251052, imipenem-cilastatin
- Where
- 24 sites in United States, Canada and 4 more
- Volunteers
- 20 people
- Sponsor
- GlaxoSmithKline
Heat Stroke, Acute Kidney Injury
Use of Sodium Bicarbonate as Prophylaxis for Kidney Damage in Patients With Heatstroke
This study protocol aims to prevent the need for renal replacement therapy in patients with rhabdomyolysis secondary to heatstroke.
- Conditions
- Heat Stroke, Acute Kidney Injury, Acute Kidney Injury Due to Hypovolaemia
- Trial name
- NCT06622525
- Testing
- Sodium bicarbonate, No intervention
- Where
- Mexico
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Hospital General de Mexicali
COVID-19, Anxiety
Remote Psychological Intervention for COVID-19 Survivors With AKI and Caregivers (REPICOV-AKI)
The frequency of psychological conditions in recovered COVID-19 patients with Acute Kidney Injury (AKI) and their informal primary caregivers (IPC) is unknown; as well as the effects of psychological therapy in this population.
- Conditions
- COVID-19, Anxiety, Depressive Symptoms, Acute Kidney Injury
- Trial name
- REPICOV-AKI (NCT06522776)
- Testing
- Cognitive behavioral therapy
- Where
- Mexico
- Volunteers
- 98 people
- Sponsor
- Jesus Rivero, MD
Sepsis, Acute Kidney Injury
A Pharmacokinetics Study of Meropenem and Piperacillin in Patients With Sepsis
This study was a single-center, open clinical study in Chinese septic patients with or without acute kidney injury. The aims of this study were to obtain the blood concentration and pharmacokinetic parameters of meropenem and…
- Trial name
- APSOMAPIPWS (NCT05807217)
- Where
- China
- Volunteers
- 44 people
- Sponsor
- Shen Ning
Prostate Cancer, Renal Cancer
HPI Effect in Robotic Urological Surgery on AKI
It is a single-center randomized controlled trial that aims to figure out the effect of the hypotension prediction index (HPI) on the prevention of acute kidney injury (AKI) after robot-assisted urological surgery.
- Conditions
- Prostate Cancer, Renal Cancer, Urologic Diseases
- Trial name
- NCT06051162
- Testing
- BP management with HPI guidance
- Where
- South Korea
- Volunteers
- 124 people
- Sponsor
- Ewha Womans University Mokdong Hospital
Acute Kidney Injury, Extracorporeal Circulation; Complications
Protein Kinase N1 Level in Patients Undergoing Cardiac Surgery
Acute kidney injury (AKI) is one of the most frequent major complications in patients undergoing cardiac surgery. CSA-AKI is independently related to increased perioperative mortality, increased hospital and ICU length of stay as…
- Conditions
- Acute Kidney Injury, Extracorporeal Circulation; Complications, Surgery
- Trial name
- NCT05386940
- Testing
- PKN1 level
- Where
- China
- Volunteers
- 110 people
- Sponsor
- Zhongnan Hospital
Acute Kidney Injury, Ischemia Reperfusion Injury
Valproic Acid (VPA) for Acute Kidney Injury (AKI) in Trauma Patients
The purpose of this study is to find out if a drug called valproic acid (VPA) will protect organs (such as the kidneys) from damage when a person is injured and loses a large amount of blood.
- Trial name
- NCT04531579
- Testing
- Valproic Acid Solution, Isotonic saline solution
- Where
- 2 sites in United States
- Sponsor
- Westat
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.