Clinical trials: Kidney Disease, Chronic
Preoperative KIDNEY FAILURE, CHRONIC, Postoperative KIDNEY FAILURE, ACUTE
NGAL Predictive Value of Acute Kidney Failure After Cardiac Surgery in Patients With Preoperative Chronic Kidney Failure
Primary endpoint: To evaluate predictive value of plasmatic levels of Neutrophil Gelatinase Associated Lipocalin (NGAL) to reveal acute kidney failure after cardiac surgery in patients with preoperative chronic kidney failure…
- Conditions
- Preoperative KIDNEY FAILURE, CHRONIC, Postoperative KIDNEY FAILURE, ACUTE, Cardiac Surgical Procedures
- Trial name
- NGAL-CKF (NCT01227122)
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Hopital Jean Minjoz
End-stage Chronic Renal Disease, Severe Acute Kidney Failure
Renal Transplantation and Inhaled Anesthetic Sevoflurane (SEVOREIN)
Renal transplantation is characterized by ischemia-reperfusion lesions in allograft. In a previous study, Julier and al. (Anesthesiology 2003) have demonstrated that sevoflurane reduces glomerular lesions in kidney of patients…
- Conditions
- End-stage Chronic Renal Disease, Severe Acute Kidney Failure, Renal Transplantation
- Trial name
- SévoRein (NCT00337051)
- Testing
- Sevoflurane, Propofol
- Where
- France
- Volunteers
- 120 people
- Sponsor
- University Hospital, Bordeaux
Frailty, Pain, Chronic
Evaluate the Impact of Targeted Physical Activity on Clinically Debilitated Dialysis Patients.
This research is being done to better understand the impact of the use of a specific physical activity training program (GH Method) in dialysis/kidney disease patients.
- Conditions
- Frailty, Pain, Chronic, Dialysis; Complications, Kidney Diseases
- Trial name
- NCT06374537
- Testing
- Muscle Therapy
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- University of Illinois Chicago
Chronic Kidney Disease Stage 2, Radiographic Contrast Agent Nephropathy
N-Acetyl Cystein and Contrast Nephropathy
There are many controversies about the role of N-Acetyl Cystein in preventing of contrast nephropathy. These contradictory results may be due to different criteria for patients' selection, different end points, different type and…
- Trial name
- NCT01820195
- Testing
- Oral N-Acetyl Cystein, IV N-Acetyl Cystein
- Where
- Iran
- Volunteers
- 549 people
- Sponsor
- Imam Khomeini Hospital
Comparison of the Efficacy of Two Formulations of Epoetin in Patients Undergoing Hemodialysis
Efficacy Study of Two Formulations of Erythropoietin
A double-blind, randomized trial aimed to compare the efficacy of two formulations of erythropoietin in patients with chronic renal failure on hemodialysis
- Trial name
- NCT01184495
- Testing
- Epoetin Alfa-BioManguinhos, Epoetin Alfa-BioSimilar
- Volunteers
- 74 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Chronic Kidney Disease Associated Anemia
A Non-interventional, Epidemiological, Registry-based Evaluation of Anaemia in Swedish Patients With Chronic Kidney Disease
The primary purpose of this study is to describe renal anemia treatment patterns in non-dialysis dependent (ND) and dialysis dependent (DD) populations, with a particular focus on iron use in erythropoiesis stimulating agent…
- Trial name
- ASK (NCT03643601)
- Testing
- Non-Interventional
- Where
- Sweden
- Volunteers
- 14,415 people
- Sponsor
- Astellas Pharma a/s
Chronic Renal Failure, Anaemia
Study of Erythropoietin (EPO) Administration Schedule
The purpose of this study is to compare the hemoglobin and hematocrit variability between once and three times weekly erythropoietin therapy for the anemia in patients with maintenance dialysis.
- Trial name
- NCT01111630
- Testing
- recomon (Epoetin Beta)
- Where
- South Korea
- Volunteers
- 60 people
- Sponsor
- JW Pharmaceutical
Kidney Failure, Chronic
Renal Osteodystrophy: An Individual Management Approach
Renal osteodystrophy (ROD) represents the bone histologic abnormalities resulting from loss of renal function. It starts early during the loss of kidney function and is seen in virtually all chronic end stage kidney disease…
- Trial name
- NCT02440581
- Testing
- Alendronate, Teriparatide, Cinacalcet
- Where
- United States
- Volunteers
- 141 people
- Sponsor
- Hartmut Malluche, MD
Fabry Disease
A Study in Patients With Fabry Disease Who Are on Chronic Hemodialysis Therapy for Treatment of End-stage Renal Insufficiency.
People with Fabry disease have an alteration in their genetic material (DNA) which causes a deficiency of the a-galactosidase A enzyme.
- Trial name
- NCT00312767
- Testing
- Fabrazyme (agalsidase beta)
- Where
- United States
- Sponsor
- Genzyme, a Sanofi Company
Heart Failure, Chronic Kidney Disease
PD-HF: A Trial of Peritoneal Dialysis in Patients With Severe Heart Failure and Chronic Kidney Disease
This trial is to establish whether ultrafiltration by peritoneal dialysis is a clinically effective treatment for patients with severe heart failure and moderate chronic kidney disease, thus improving quality of life and symptoms.
- Trial name
- PD-HF (NCT02708407)
- Testing
- Peritoneal Dialysis
- Where
- United Kingdom
- Volunteers
- 11 people
- Sponsor
- University of Nottingham
Multiple Myeloma
A Study of Belantamab Mafodotin Monotherapy in Multiple Myeloma Participants With Normal and Varying Degree of Impaired Renal Function
Belantamab mafodotin is an antibody-drug conjugate (ADC) containing humanized anti- B-cell maturation antigen (BCMA) monoclonal antibody (mAb).
- Trial name
- DREAMM12 (NCT04398745)
- Testing
- Belantamab mafodotin
- Where
- 4 sites in Greece, South Korea
- Volunteers
- 36 people
- Sponsor
- GlaxoSmithKline
Chronic Kidney Diseases, Pruritus
A Study to Evaluate the Safety and Efficacy of CR845 in Chronic Kidney Disease Patients With Moderate-to-Severe Pruritus
This is a multicenter, double-blind, randomized, placebo-controlled study to evaluate the safety and efficacy of 3 dose levels of oral CR845 compared to placebo in reducing the intensity of itch in chronic kidney disease (CKD)…
- Trial name
- NCT03617536
- Testing
- CR845 0.25 mg Oral Tablet, CR845 0.5 mg Oral Tablet, CR845 1 mg Oral Tablet
- Where
- 60 sites in United States
- Volunteers
- 269 people
- Sponsor
- Cara Therapeutics, Inc.
Chronic Kidney Disease, Pediatric Urology
Safety of Short-course of NSAIDs in Pediatric Patients With CKD
The purpose of this study is to determine if non-steroidal anti-inflammatory (NSAID) use in the postoperative setting increases the risk of acute kidney injury (AKI) in pediatric patients with mild-to-moderate chronic kidney…
- Trial name
- NCT06860711
- Testing
- NSAIDs
- Where
- United States
- Volunteers
- 164 people
- Sponsor
- University of Colorado, Denver
Anemia
Comparison of Oral Iron With IV Iron in Patients With Anemia of Chronic Renal Failure Not on Dialysis
The purpose of the study was to compare the efficacy of oral iron (ferrous sulfate) plus erythropoietin to Iron Sucrose plus erythropoietin for managing anemia patients with chronic renal failure who are not receiving dialysis.
- Trial name
- NCT00236964
- Testing
- Iron Sucrose + Erythropoietin, Oral Iron + Erythropoietin
- Volunteers
- 96 people
- Sponsor
- American Regent, Inc.
Gout, Chronic Kidney Disease (CKD)
A Phase 4 Safety and Efficacy Study to Evaluate Lesinurad 200 mg in Participants With Gout and Renal Impairment
This study evaluates the safety and efficacy of lesinurad administered with an XOI versus a placebo plus an XOI in gout participants who have moderate renal impairment and who are not at target level of serum urate (sUA).
- Trial name
- NCT03226899
- Testing
- Lesinurad, XOI, colchicine
- Where
- 116 sites in United States, Czechia and 2 more
- Volunteers
- 242 people
- Sponsor
- Ironwood Pharmaceuticals, Inc.
Chronic Renal Failure
Cost Utility Analysis of Erythropoietin for Anemia Treatment in Hemodialysis Patients
To study the cost utility analysis of Erythropoietin (EPO) for maintaining the different hemoglobin (Hb) target levels in anemic hemodialysis patient in routine clinical practice.
- Trial name
- CUAEPO (NCT01049711)
- Testing
- erythropoietin
- Where
- Thailand
- Volunteers
- 152 people
- Sponsor
- Mahidol University
Kidney Disease, Kidney Transplantation
Role of Donor Genetics and Recipient Genetics in Kidney Transplant Outcomes
Background: Genetic variation in a particular chromosome is a major contributor to the increased risk for kidney disease that is common in people of African descent, although the specific gene, mutations, and other aspects of the…
- Conditions
- Kidney Disease, Kidney Transplantation, Kidney Failure, Chronic
- Trial name
- NCT01143532
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Chronic Kidney Disease (Stages 1-4)
CommunityRx-Kidney Health
In the United States, the burden of chronic kidney disease (CKD) rests disproportionately on rural communities. This study evaluates the implementation and effectiveness of CommunityRx-Kidney Health (CRx-K); this health…
- Trial name
- CRx-K (NCT07237295)
- Testing
- CommunityRx-Kidney Health
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- University of North Carolina, Chapel Hill
End Stage Renal Disease, Haemodialysis
Combination of Medium Cut-off Dialyzer Membrane and Diet Modification to Alleviate Residual Uremic Syndrome of Dialysis Patients
The study will compare achieved levels of protein-bound uremic toxins with dialysis using a medium cut-off membrane compared to the treatment by online haemodiafiltration with a high-flux dialysis membrane.
- Conditions
- End Stage Renal Disease, Haemodialysis, Diet, Healthy
- Trial name
- NCT04247867
- Testing
- medium cut-off (MCO) dialysis membrane, Dietary fiber mixture (Plantago Psyllium and Inulin), Sodium propionate
- Where
- Slovenia
- Volunteers
- 50 people
- Sponsor
- University Medical Centre Ljubljana
ESRD, Renal Failure
Artegraft Versus Propaten Dialysis Grafts
Compare Artegraft and Propaten grafts for use in dialysis access to see if one performs better than the other. How long each one lasts until a complication arises or until the graft is no longer used will be compared.
- Trial name
- NCT02099344
- Testing
- Artegraft, Propaten
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Kaiser Permanente
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