Clinical trials: Kidney Disease, Chronic
Renal Insufficiency, Chronic
To Investigate Pharmacokinetics (Absorption, Distribution, Elimination), Safety and Tolerability of a Single Oral Dose of 75 mg Molidustat Tablet in Male and Female Subjects Requiring Hemo- or Peritoneal Dialysis Compared to Healthy Subjects
The study investigates the pharmacokinetics (absorption, distribution, elimination) of molidustat after intake of a single 75 mg tablet in subjects with renal impairment requiring hemo- or peritoneal dialysis compared to age-and…
- Trial name
- NCT02312973
- Testing
- Molidustat(BAY85-3934)
- Where
- 2 sites in Germany
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Bayer
Anemia
A Study of Intravenous Mircera in Hemodialysis Patients With Chronic Renal Anemia
This single arm study will assess the efficacy, safety and tolerability of once-monthly administration of intravenous Mircera for the maintenance of hemoglobin levels in hemodialysis patients with chronic renal anemia.
- Trial name
- NCT00661505
- Testing
- methoxy polyethylene glycol-epoetin beta
- Where
- 20 sites in Turkey (Türkiye)
- Volunteers
- 132 people
- Sponsor
- Hoffmann-La Roche
Chronic Kidney Disease
Artificial Intelligence Model to Predict Chronic Kidney Outcomes in a Vietnamese Cohort
Chronic kidney disease (CKD) is a common condition that imposes a substantial health burden and contributes significantly to global morbidity and mortality.
- Trial name
- NCT07751939
- Where
- Vietnam
- Volunteers
- 1,182 people
- Sponsor
- University Medical Center Ho Chi Minh City (UMC)
Vascular Calcification
Oral Alfacalcidol and Coronary Artery Calcification in Predialysis Chronic Kidney Disease
Active vitamin D at therapeutic dose may prevent vascular calcification but in supraphysiologic dose may precipitate it.
- Trial name
- NCT01364688
- Testing
- oral alfacalcidol, no drug
- Where
- Thailand
- Volunteers
- 80 people
- Sponsor
- Ramathibodi Hospital
Kidney Failure, Chronic
Short Term Effects of FX Dialysers on QOL and Inflammation
Background: The new hollow fibre FX-class of dialysers (Fresenius Medical Care, Bad Homburg, Germany) features a number of technological improvements that may benefit the patient.
- Trial name
- NCT00291603
- Testing
- FX-class of dialyser
- Where
- Australia
- Volunteers
- 50 people
- Sponsor
- Sir Charles Gairdner Hospital
Declination of Glomerular Infiltration Rate in Chronic Kidney Disease Population
Effect of Intensive Low Sodium Restriction on Glomerular Infiltration Rate in Chronic Kidney Disease
Introduction : Due to Chronic kidney disease is a public health problem, which is important increased in both developed and developing countries .
- Trial name
- NCT02519894
- Testing
- Dietary Scanning Calculator
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- PANTHITA SORNHIRAN
Cramps, Chronic Kidney Disease(CKD)
Prevalence and Severity of Cramps in Chronic Kidney Disease Patients
Cramps are a frequent and severe complication in CKD patients. Their characteristics : triggering factors, associated factors, are not well known. There is no recognized effective treatment.
- Trial name
- CRAMéREIN (NCT06737094)
- Where
- France
- Volunteers
- 250 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
End Stage Renal Disease, Kidney Disease, Chronic
Feasibility Study of Telemedicine for Dialysis Patients Awaiting Transplantation
The purpose of this study is to determine whether a telemedicine follow-up visit at the NYU Langone Transplant Institute is a feasible and acceptable alternative to a traditional in-center follow-up visit.
- Trial name
- NCT03189212
- Testing
- Usual Care Visit, Telemedicine Visit
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- NYU Langone Health
End-Stage Renal Disease
Decellularized Femoral Artery Allograft (Nexeon AVX) Prospective Registry
Post market registry to assess the safety and efficacy of a novel decellularized human femoral artery allograft (Nexeon AVX Decellularized Femoral Artery,
- Trial name
- NCT05880537
- Testing
- Nexeon Arterial Venous Allograft
- Where
- 4 sites in United States
- Volunteers
- 100 people
- Sponsor
- LifeNet Health
Chronic Kidney Disease
Opioids in Chronic Kidney Disease Patients Undergoing Hemodialysis
To measure oxycodone's intradialytic mass transfer rate coefficient and oxycodone's removal rate using an ODE/PDE hemodialysis model.
- Trial name
- OCKD (NCT02452437)
- Testing
- Oxycodone
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Emerio & Lourdes Linares Research and Education Center
End Stage Renal Disease, Sexual Dysfunction, Physiological
Pain, Sexual Dysfunction, and Depression in Hemodialysis Patients
This study is seeking to identify the most effective strategy to manage pain, sexual dysfunction, and depression in patients receiving chronic hemodialysis therapy.
- Conditions
- End Stage Renal Disease, Sexual Dysfunction, Physiological, Pain, Depression
- Trial name
- SMILE (NCT00692419)
- Testing
- Symptom management nurse intervention, Feedback intervention
- Where
- United States
- Volunteers
- 315 people
- Sponsor
- US Department of Veterans Affairs
Coronary Disease, Cardiovascular Diseases
Cardiac and Renal Disease Study (CARDS)
To examine the epidemiology of renal disease and its relationship to cardiovascular disease.
- Conditions
- Coronary Disease, Cardiovascular Diseases, Cerebrovascular Accident, Heart Failure
- Trial name
- NCT00049907
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Kidney Transplant; Complications, Renal Failure Chronic
Comparison of Two Different Preload Targets of Stroke Volume Variation During Kidney Transplantation
The investigators sought to compare the effect of two preload targets of stroke volume variation of ≤6% and ≤12% on the postoperative renal function in patients undergoing living donor kidney transplantation.
- Trial name
- NCT03949036
- Testing
- Crystalloid fluid administration with the target of stroke volume variation ≤ 12%, Crystalloid fluid administration with the target of stroke volume variation ≤ 6%
- Where
- South Korea
- Volunteers
- 60 people
- Sponsor
- Seoul National University Hospital
Healthy Volunteers
Effects of Ferrous Sulfate on the Pharmacokinetics of AKB-6548
The primary purpose of this study is to assess the single-dose bioavailability of AKB-6548 with ferrous sulfate relative to AKB-6548 in healthy volunteers.
- Trial name
- NCT02327546
- Testing
- AKB-6548, Ferrous Sulfate
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Akebia Therapeutics
ESRD
Glucose Metabolism During Hemodialysis
Disturbed glucose metabolism is a common feature of patients with end-stage renal disease (ESRD). Several hormones responsible of a stable blood glucose including insulin, glucagon, and the gastrointestinal insulinotropic…
- Trial name
- NCT01800188
- Testing
- Hemodialysis, Hemodiafiltration, Meal test
- Where
- Denmark
- Volunteers
- 10 people
- Sponsor
- Bo Feldt-Rasmussen
Calcific Uremic Arteriolopathy (CUA), Calciphylaxis
European Calciphylaxis Registry Network
Observational, registry, prospective, non-interventional collection of CUA patient data. Patient treatment is carried out within clinical routine, at the discretion of the physicians and according to existing treatment…
- Trial name
- EuCalNet (NCT02635373)
- Where
- Germany
- Volunteers
- 1,000 people
- Sponsor
- RWTH Aachen University
Chronic Kidney Disease
REVEAL-CKD: Prevalence and Consequences of Undiagnosed Chronic Kidney Disease
This is a retrospective, multinational, non-interventional, observational study. A series of cohort studies will be conducted to assess the prevalence of undiagnosed stage 3 CKD in each region.
- Trial name
- REVEAL-CKD (NCT04847531)
- Where
- 13 sites in United States, Australia and 9 more
- Volunteers
- 1,006,361 people
- Sponsor
- AstraZeneca
Chronic Kidney Diseases, Inflammation
Effects of Microencapsulated Propolis and Turmeric in Patients With Chronic Kidney Disease
Oxidative stress and inflammation are correlated with Chronic Kidney Disease (CKD), in a way that they bring several harms to patients, including an increased risk of cardiovascular disease and mortality.
- Trial name
- NCT05183737
- Testing
- Microcapsules with turmeric and propolis
- Where
- Brazil
- Volunteers
- 34 people
- Sponsor
- Universidade Federal Fluminense
Pentoxifylline, Inflammatory Markers
Pentoxifylline on Inflammatory Markers in Non-Diabetic Chronic Kidney Disease Patients
This study aimed to determine the impact of Pentoxifylline on inflammatory biomarkers and the progression of chronic kidney disease in non-diabetic patients.
- Conditions
- Pentoxifylline, Inflammatory Markers, Non-Diabetic, Chronic Kidney Disease
- Trial name
- NCT07315139
- Testing
- Angiotensin-converting enzyme inhibitors (Ramipril), Pentoxifylline
- Where
- Egypt
- Volunteers
- 42 people
- Sponsor
- Ain Shams University
Peritoneal Dialysis, Renal Disease, End-Stage
Does Extra-High Dose Hepatitis B Vaccination Confer Longer Serological Protection in Peritoneal Dialysis Patients?
Hepatitis B virus causes inflammation of the liver which is detrimental to the end-stage renal disease patients on dialysis. Hepatitis B vaccine is recommended for this high-risk population although the vaccine protection remains…
- Trial name
- NCT00125775
- Testing
- Engerix-B
- Where
- Hong Kong
- Volunteers
- 130 people
- Sponsor
- Chinese University of Hong Kong
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