Clinical trials: Kidney Disease, Chronic
End-Stage Kidney Disease
Effect of Ursodeoxycholic Acid on Peritoneal Function in Patients on Peritoneal Dialysis
Peritoneal fibrosis is one of the major causes of technical failure in patients on peritoneal dialysis (PD) for long period of time.
- Trial name
- NCT02338635
- Testing
- Ursodeoxycholic Acid
- Volunteers
- 55 people
- Sponsor
- Ewha Womans University
End Stage Renal Disease
A Cluster-randomized, Pragmatic Trial of Hemodialysis Session Duration
The purpose of the TiME Trial is to determine whether dialysis facility implementation of a minimum hemodialysis session duration of 4.25 hours (versus usual care) for patients with end-stage renal disease initiating treatment…
- Trial name
- TiME (NCT02019225)
- Testing
- Dialysis session of at least 4.25 hours
- Where
- 2 sites in United States
- Volunteers
- 7,053 people
- Sponsor
- University of Pennsylvania
Chronic Kidney Diseases
Description of Treatment Patterns and Population Characteristics of Pre-dialysis CKD Patients in the Czech Republic
The decision making in the Czech nephrology offices depends on the local common practice which is likely to be heterogenous. In other words, the same patient would be indicated to different therapy and regimen at different sites.
- Trial name
- NCT05380843
- Where
- 5 sites in Czechia
- Volunteers
- 1,200 people
- Sponsor
- Value Outcomes Ltd.
End-stage Renal Disease
French Renal Epidemiology and Information Network (REIN) Registry
The Renal Epidemiology and Information Network (REIN) Registry was created in 2002 (after study pilot in 2001) to contribute to the development and evaluation of health strategies aiming at improving prevention and management of…
- Trial name
- REIN-LOR (NCT03967808)
- Where
- France
- Volunteers
- 6,000 people
- Sponsor
- Central Hospital, Nancy, France
Kidney Diseases, Muscle Loss
Protein and Exercise Training in Chronic KIDNEY Disease
When patients progress to the final stage of chronic kidney disease (CKD) and require hemodialysis treatment, they typically have lost so much muscle function that they are no longer physically independent.
- Trial name
- PET KIDNEY (NCT05482243)
- Testing
- Whey protein
- Where
- Netherlands
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Kidney Failure, Chronic
Renal Osteodystrophy: An Individual Management Approach
Renal osteodystrophy (ROD) represents the bone histologic abnormalities resulting from loss of renal function. It starts early during the loss of kidney function and is seen in virtually all chronic end stage kidney disease…
- Trial name
- NCT02440581
- Testing
- Alendronate, Teriparatide, Cinacalcet
- Where
- United States
- Volunteers
- 141 people
- Sponsor
- Hartmut Malluche, MD
Chronic Kidney Disease
A Phase III Clinical Study on the Efficacy and Safety of HRS-1780 in the Treatment of Patients With Chronic Kidney Disease
The study is a Phase III clinical trial to evaluate the superiority of HRS-1780 tablets compared with placebo in delaying renal function decline in participants with chronic kidney disease (CKD) on the basis of standard treatment.
- Trial name
- NCT07419828
- Testing
- HRS-1780 tablets
- Where
- China
- Volunteers
- 5,386 people
- Sponsor
- Shandong Suncadia Medicine Co., Ltd.
End Stage Renal Disease, Peritoneal Dialysis Complication
The Effect of Home Based Tele-Exercise on Peritoneal Dialysis Patients
Brief Summary: The objective of the trial is to assess the effect of synchronous home-based tele exercise on daily activity level, functional status and frailty level in Peritoneal Dialysis patients.
- Trial name
- NCT06787599
- Testing
- Home-based Tele Exercise
- Where
- Iran
- Volunteers
- 30 people
- Sponsor
- Pardis Specialized Wellness Institute
End Stage Renal Disease, Arteriovenous Fistula
Changes in Cardiac Structure and Function After Establishment of Autologous Arteriovenous Fistula
This study is a retrospective cohort study aimed at evaluating the impact of autologous arteriovenous fistula (AVF) on the heart, especially the left atrial structure, in patients with end-stage renal disease (ESRD) through a…
- Trial name
- NCT06199609
- Testing
- Hemodialysis pathway, AVF
- Where
- China
- Volunteers
- 2,027 people
- Sponsor
- Haiyan Wang
Chronic Kidney Disease
Renal Impairment Study for Oral EC5026
The goal of this Phase 1 clinical trial is to assess single dose pharmacokinetics of oral EC5026 in a population with chronic kidney disease. The main questions it aims to answer are: 1.
- Trial name
- NCT07694544
- Testing
- EC5026 oral tablet
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- EicOsis Human Health Inc.
Chronic Renal Failure, End-Stage Renal Disease
Dietary Protein Requirements in Hemodialysis Patients
The primary purpose of this study is to assess dietary protein requirements in clinically stable maintenance hemodialysis (MHD) patients.
- Trial name
- NCT02194114
- Testing
- Protein Diet
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center
Coronary Artery Disease, Chronic Kidney Disease
Clinical Feature and Outcome of Angiographic Coronary Artery Disease in Chronic Kidney Disease Patients
The prevalence and mortality rate of cardiovascular disease (CVD) in chronic kidney disease (CKD) patients is high. The prevalence of coronary artery disease (CAD) in CKD population ranges from 38 to 65%, with an average of 3.3…
- Trial name
- NCT00651521
- Where
- Taiwan
- Volunteers
- 1,000 people
- Sponsor
- Chang Gung Memorial Hospital
Chronic Nephropathy
Effects of Atorvastatin Versus Probucol on Small Dense LDL
Small dense low-density lipoprotein (LDL) plays an important role in causing glomerular injury through conversion to an oxidatively modified form of LDL.
- Trial name
- NCT00276133
- Testing
- Effects of atorvastatin versus probucol on small dense LDL
- Where
- Japan
- Volunteers
- 24 people
- Sponsor
- Yokohama City University Medical Center
Chronic Kidney Disease
Vascular Changes Following Forearm Loop Arteriovenous Graft Placement
This study will determine whether upper arm vessels increase in size following forearm loop arteriovenous graft placement and the timing of these changes.
- Trial name
- NCT00836563
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Nebraska
Uncontrolled Hypertension, Renal Denervation
Renal Denervation in Chronic Kidney Disease - RDN-CKD Study
RDN-CKD GR Study is a prospective, randomized (1:1), double-blind (unblinded interventionalist and blinded study team), sham controlled study.
- Conditions
- Uncontrolled Hypertension, Renal Denervation, Chronic Kidney Disease (Stage 3)
- Trial name
- RDN-CKD GR (NCT07742787)
- Testing
- Renal denervation
- Where
- Greece
- Volunteers
- 20 people
- Sponsor
- Hippocration General Hospital
Renal Insufficiency, Chronic, Kidney Failure, Chronic
Effects of a Mindfulness-based Intervention in Stress, Pain and Quality of Life in People Undergoing Hemodialysis
This project has as main objective to evaluate the effects of a Mindfulness-based intervention (MBI) in the reduction of stressors, pain and quality of life of people with chronic kidney disease undergoing hemodialysis (HD).
- Conditions
- Renal Insufficiency, Chronic, Kidney Failure, Chronic, Kidney Diseases, Kidney Insufficiency, Chronic
- Trial name
- NCT04610593
- Testing
- Mindfulness-based Intervention
- Where
- Brazil
- Volunteers
- 32 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Chronic Kidney Disease(CKD)
Medication Adherence Given Individual SystemCHANGE(TM) in Advancing Nephropathy (MAGICIAN) Pilot Study
The purpose of this 2-group, randomized, controlled trial is to evaluate the refined SystemCHANGE™ against attention control patient education in CKD patients taking RAAS medications.
- Trial name
- MAGICIAN (NCT04616612)
- Testing
- SystemCHANGE (TM), Attention Control
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Indiana University
End Stage Kidney Disease
Symptom Monitoring in Hemodialysis
The SMaRRT-HD trial is a cluster randomized trial of symptom monitoring with supported clinician follow-up using the SMaRRT-HD electronic patient reported outcome measure (ePROM) system versus Usual Care.
- Trial name
- SMaRRT-HD (NCT05738330)
- Testing
- Symptom Monitoring on Renal Replacement Therapy - Hemodialysis (SMaRRT-HD), Usual Care
- Where
- United States
- Volunteers
- 2,400 people
- Sponsor
- University of Pennsylvania
End-Stage Renal Disease
Association of FGF-23 and Parathyroid Hormone (PTH) in Dialysis Patients
The purpose of this study is to determine how levels of this newly-discovered hormone, called FGF-23, changes in the blood in response to a high calcium dialysis bath during a hemodialysis (HD) treatment, and how this relates to…
- Trial name
- NCT00477516
- Testing
- exposure to a high-calcium dialysate bath
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- James B. Wetmore, MD
Chronic Kidney Disease, Chronic Renal Disease
Study of How the Dose of Dialysis is Affected by Dialysate Flow Rate
The purpose of this study is to look at how the dose of dialysis is affected by the rate at which dialysate flows through the dialyzer.
- Trial name
- NCT00962000
- Testing
- Dialysis Flow Rate Start 600mL/min, Dialysis Flow Rate Start 800mL/min
- Where
- 3 sites in United States
- Volunteers
- 42 people
- Sponsor
- Vantive Health LLC
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