Clinical trials: Kidney Disease, Chronic
Hemodialysis, Chronic Kidney Disease
Effect of Pecha Kucha Education on Fluid and Diet Adherence in Hemodialysis Patients
This randomized controlled trial aims to evaluate the effect of education based on the Pecha Kucha presentation technique on fluid and dietary adherence in patients undergoing hemodialysis.
- Trial name
- NCT07518017
- Testing
- Pecha Kucha Education, Standard Education
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people
- Sponsor
- Büşra Ceren DEMİREL YILDIZ
Anemia, Chronic Kidney Disease
Peginesatide for Anemia in Chronic Hemodialysis Patients
The purpose of this study is to evaluate the safety, pharmacodynamics (PD), and pharmacokinetics (PK) of multiple intravenous doses of peginesatide in participants with chronic kidney disease (CKD) who are on hemodialysis.
- Conditions
- Anemia, Chronic Kidney Disease, Chronic Renal Failure
- Trial name
- NCT00228449
- Testing
- peginesatide
- Where
- 14 sites in United States
- Volunteers
- 165 people
- Sponsor
- Affymax
Chronic Kidney Disease
Effects of Low Protein Diet Supplemented Keto-/Amino Acid in Preventing the Progression of Chronic Kidney Disease (CKD)- ELPD Study
The purpose of this study is to determine whether low protein diet and very low protein diet supplemented keto-/amino acid is effective in preventing the progression of chronic kidney disease (CKD , stage 3b and 4).
- Trial name
- ELPD-CKD (NCT01418508)
- Testing
- low protein diet plus α-keto acid, very low protein diet plus α-keto acid
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Peking Union Medical College Hospital
Chronic Renal Insufficiency, Hemodialysis
Effect of a Concurrent Physical Exercise Program in Hemodialysis Patients
Concurrent physical exercise is the method of combining strength and endurance that can be worked with in one session or in an exercise program.
- Trial name
- NCT06664385
- Testing
- concurrent physical exercise
- Where
- Mexico
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Pedro Julian Flores Moreno
Hypertension, Heart Failure
Influence of Catheter-based Renal Denervation in Diseases With Increased Sympathetic Activity
The study is aiming to document the long-term safety and effectiveness of renal denervation in patients with hypertension and other diseases characterized by elevated sympathetic drive.
- Conditions
- Hypertension, Heart Failure, Chronic Kidney Disease, Diabetes
- Trial name
- NCT01888315
- Testing
- Renal denervation with Symplicity Flex Medtronic/Ardian, Renal denervation with EnligHTN St. Jude Medical, Renal denervation with Paradise Recor
- Where
- Germany
- Volunteers
- 1,000 people
- Sponsor
- University Hospital, Saarland
Continuous Glucose Monitoring, ESRD (End-Stage Renal Disease)
Continuous Glucose Monitoring and Clinical Outcomes in Diabetes on Peritoneal Dialysis
This prospective, multicenter observational study will evaluate glucose profiles using continuous glucose monitoring (CGM) in 100 adults with diabetes receiving peritoneal dialysis (PD) or planning to start PD within 3 months.
- Conditions
- Continuous Glucose Monitoring, ESRD (End-Stage Renal Disease), Peritoneal Dialysis (PD), Diabetes Mellitus (DM)
- Trial name
- GLANCE-PD (NCT07790276)
- Testing
- Continuous glucose monitoring system
- Where
- Hong Kong
- Volunteers
- 100 people
- Sponsor
- Elaine Chow
Chronic Kidney Diseases
Impact of Dapagliflozin on Intestinal Microbiota Composition and on the Metabolites Derived From the Intestinal Microbiota in Non-diabetic Chronic Renal Failure Patients
Chronic kidney disease (CKD) is a common disease affecting 10-12% of the adult population and characterize with high-risk cardiovascular morbidity and mortality with progression of CKD.
- Trial name
- DAPA-GUT (NCT05965440)
- Testing
- impact of Dapagliflozin on Intestinal Microbiota on chronic renal failure patients
- Where
- France
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
End-Stage Renal Disease, Hemodialysis
Hemocontrol and Blood Pressure Control in Dialysis Patients
Volume overload contributes significantly to the pathogenesis of hypertension in hemodialysis patients. The Hemocontrol(HC)system (Gambro), which automatically adjusts ultrafiltration rate and dialysate conductivity according to…
- Trial name
- NCT00319774
- Testing
- Hemocontrol Biofeedback System
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- Université de Montréal
Hepatorenal Syndrome, Cirrhosis, Liver
Point-of-Care Echocardiography to Assess Impact of Dynamic Cardiac Function, Renal and Cardiac Biomarkers in Cirrhosis With Hepatorenal Syndrome-Acute Kidney Injury
Point-of-care echocardiography (POC-Echo) is used to determine left ventricular systolic and diastolic dysfunction (LVDD), inferior vena cava (IVC) dynamics and volume status in cirrhosis and Acute-on-chronic liver failure ACLF…
- Conditions
- Hepatorenal Syndrome, Cirrhosis, Liver, Acute-On-Chronic Liver Failure, AKI
- Trial name
- NCT05434286
- Testing
- Echocardiographic assessment
- Where
- India
- Volunteers
- 75 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Heart Failure
BAY94-8862 Dose Finding Trial in Subjects With Chronic Heart Failure and Mild (Part A) or Moderate (Part B) Chronic Kidney Disease
A placebo (Part A) and placebo and active comparator controlled (Part B), double-blind and randomized study to assess safety and tolerability of a new drug (BAY94-8862) given orally
- Trial name
- ARTS (NCT01345656)
- Testing
- BAY94-8862, Spironolactone
- Where
- 50 sites in Austria, Belgium and 8 more
- Volunteers
- 457 people
- Sponsor
- Bayer
Diabetes Mellitus, Renal Insufficiency, Chronic
Improving Health Literacy on Chronic Kidney Disease Among Diabetics: the Malaysian Nutritional, Emotional and Physical Health Literacy for Optimal Renal Outcome (My-NEPHRO) Trial
The goal of this clinical trial is to learn if a health literacy module via mobile application intervention can improve health outcomes and health literacy in diabetics with chronic kidney disease and could include any of the…
- Conditions
- Diabetes Mellitus, Renal Insufficiency, Chronic, Health Literacy, Quality of Life
- Trial name
- NCT07836556
- Testing
- Mobile application
- Volunteers
- 102 people
- Sponsor
- Universiti Sultan Zainal Abidin
Chronic Kidney Diseases, Particulate Matter
Assessment of Health Effects of Air Purifier Interventions on Chronic Kidney Disease Patients
This exploratory study investigates the impact of indoor air quality improvement via air purifiers on the health of chronic kidney disease (CKD) patients.
- Trial name
- NCT06963372
- Where
- South Korea
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Inha University Hospital
Contrast-induced Nephropathy, Kidney Injury
Intravenous vs. Oral Hydration to Reduce the Risk of Post-Contrast Acute Kidney Injury After Intravenous Contrast-Enhanced Computed Tomography in Patients With Severe Chronic Kidney Disease
The use of contrast media (CM) poses a risk of post-contrast acute kidney injury (PC-AKI), especially among patients chronic kidney disease (CKD).
- Conditions
- Contrast-induced Nephropathy, Kidney Injury, Kidney Failure, Chronic, Risk Reduction
- Trial name
- ENRICH (NCT05283512)
- Testing
- Preventive treatment with IV-hydration, Preventive treatment with oral hydration
- Where
- Denmark
- Volunteers
- 254 people
- Sponsor
- Odense University Hospital
End Stage Renal Disease (ESRD)
Effect of PMR on Pain In Patients With ESRD
Background: Patients with chronic end-stage renal disease (ESRD) commonly experience chronic pain, which significantly impair their quality of life.
- Trial name
- NCT07061028
- Testing
- Progressive Muscle Relaxation, Control Group
- Where
- Jordan
- Volunteers
- 104 people
- Sponsor
- Jordan University of Science and Technology
Chronic Kidney Failure
Observational Study of Kibow Biotics in Chronic Kidney Failure Patients
A specifically formulated probiotic product comprised of defined and tested microbial strains may afford renoprotection in what has been generally called "Enteric DialysisTM".
- Trial name
- NCT01450657
- Testing
- Kibow Biotics/Renadyl
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- Kibow Pharma
Kidney Failure, Chronic
Saving Residual Renal Function Among Haemodialysis Patients Receiving Irbesartan
Angiotensin II receptor blockers (ARB) are known to preserve kidney function among patients with kidney diseases and reduced renal function, but not among haemodialysis patients.
- Trial name
- SAFIR (NCT00791830)
- Testing
- Irbesartan
- Where
- 6 sites in Denmark
- Volunteers
- 82 people
- Sponsor
- University of Aarhus
End-stage Renal Disease, Hemodialysis
Does Moderate Physical Activity in Hemodialysis Patients Reduce Inflammation?
The purpose of this study is to observe a potential benefit of moderate physical activity by using bed mounted cycles during hemodialysis treatment sessions on inflammatory markers in the blood of patients with end-stage renal…
- Trial name
- NCT00893165
- Testing
- moderate physical activity
- Where
- Germany
- Volunteers
- 16 people
- Sponsor
- Martin-Luther-Universität Halle-Wittenberg
Chronic Kidney Failure, Secondary Hyperparathyroidism
Paricalcitol Oral Therapy in Predialysis CKD Patients. The Greek Experience
The purpose of this study is to obtain data on the use of Zemplar (paricalcitol) capsules in real-life clinical practice in predialysis patients with chronic kidney disease (CKD) and secondary hyperparathyroidism.
- Trial name
- PROTECT (NCT01083186)
- Where
- 24 sites in Greece
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- AbbVie (prior sponsor, Abbott)
Chronic Kidney Diseases
Aerobic Exercise in Patients With CKD
Patients with chronic kidney disease (CKD), especially those who are on dialysis, have a high prevalence of cardiovascular mortality and among the risk factors; inflammation and oxidative stress stand out.
- Trial name
- NCT04375553
- Testing
- Aerobic exercise
- Where
- Brazil
- Volunteers
- 32 people
- Sponsor
- Universidade Federal Fluminense
Heart Failure With Preserved Ejection Fraction, End Stage Renal Disease on Dialysis
EMPAgliflozin in Heart Failure With PReserved Ejection Fraction and End Stage Renal Disease
The presence of CKD has been linked to the development of HFpEF. Currently, the treatment for HFpEF is limited. SGLT2i are one of the few drug classes that have proven efficacy in HFpEF in randomized controlled trials.
- Trial name
- EMPA-PRED (NCT06249945)
- Testing
- Empagliflozin 25 MG
- Where
- 2 sites in Taiwan
- Volunteers
- 150 people
- Sponsor
- National Taiwan University Hospital
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