Clinical trials: Kidney Failure, Chronic
Chronic Kidney Disease, Chronic Renal Insufficiency
STAAR-3 Clinical Study
To assess the effect of Aranesp on the hemoglobin (Hgb) of CRI subjects who are recombinant human erythropoietin (rHuEPO)-naïve or converting from rHuEPO therapy.
- Conditions
- Chronic Kidney Disease, Chronic Renal Insufficiency, Kidney Disease, Pre-dialysis
- Trial name
- NCT00369733
- Testing
- Darbepoetin alfa
- Volunteers
- 443 people
- Sponsor
- Amgen
Chronic Kidney Failure, HIV Infection
Kidney Transplant for HIV-Infected Patients in Renal Failure
This study will examine the safety and effectiveness of renal (kidney) transplantation for HIV-infected patients with end-stage renal disease (kidney failure).
- Trial name
- NCT00009009
- Testing
- immunosuppressive regimen designed to complement HAART
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Chronic Kidney Diseases
DYNAMic Renal Assessment: NOvel Methods to Assess KIDNEY Functional Reserve
This is a feasibility study to assess new, more practical ways of measuring renal reserve.
- Trial name
- DYNAMO (NCT06572215)
- Testing
- Dapagliflozin
- Where
- United Kingdom
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- King's College Hospital NHS Trust
Chronic Kidney Diseases, Hemodialysis Complication
Mindfulness Meditation For Hemodialysis Patients
Objective: This study aimed to examine the effects of mindfulness meditation on trait mindfulness, perceived stress, emotion regulation, and quality of life in end-stage renal disease patients undergoing hemodialysis.
- Trial name
- NCT05176730
- Testing
- Mindfulness meditation
- Where
- Jordan
- Volunteers
- 74 people
- Sponsor
- Jordan University of Science and Technology
End-Stage Renal Disease
Association of FGF-23 and Parathyroid Hormone (PTH) in Dialysis Patients
The purpose of this study is to determine how levels of this newly-discovered hormone, called FGF-23, changes in the blood in response to a high calcium dialysis bath during a hemodialysis (HD) treatment, and how this relates to…
- Trial name
- NCT00477516
- Testing
- exposure to a high-calcium dialysate bath
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- James B. Wetmore, MD
End Stage Renal Disease
A Pilot Study To Evaluate The CreatiVasc Hemoaccess Valve System In Patients Requiring Arteriovenous Graft Placement
The ability to selectively control blood flow through an arteriovenous (AV) graft only when it is needed for dialysis may reduce the current repetitive complications such as thrombosis, venous hypertension post-dialysis bleeding…
- Trial name
- NCT01644526
- Testing
- Hemoaccess Valve System
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Diaxamed LLC
Chronic Kidney Disease, Type 2 Diabetes
Rapid and Simultaneous Initiation of Four Guideline-Directed CKD Therapies (RAPID-CKD)
The goal of this clinical trial is to learn if starting four kidney disease medicines quickly and together (a rapid treatment approach) is safe and works well in people with type 2 diabetes and chronic kidney disease.
- Trial name
- RAPID-CKD (NCT07547878)
- Testing
- Finerenone, Semaglutide, Lotensin
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- Baylor Research Institute
Chronic Kidney Disease, End-stage Renal Disease
Home-based Exercise in Chronic Kidney Disease
A home-based exercise program will be implemented in three different groups of participants: advanced chronic kidney disease, end-stage renal disease in substitutive treatment hemodialysis or peritoneal dialysis.
- Trial name
- HBCKD-BCN (NCT03621176)
- Testing
- Home-based exercise
- Where
- Spain
- Volunteers
- 57 people
- Sponsor
- Cardenal Herrera University
End Stage Renal Disease
Protein Supplementation in Dialysis Patients
Poor nutritional status as evidenced by low body mass index, low muscle mass or low serum albumin is a strong predictor of morbidity and mortality in dialysis patients.
- Trial name
- NCT01855295
- Testing
- Protein Supplement
- Volunteers
- 73 people
- Sponsor
- University of Utah
End-stage Renal Disease (ESRD)
NIRS for the Diagnosis of Residual Renal Function Injury in Hemodialysis Patients
Hemodialysis (HD) is the main renal replacement therapy for patients with end-stage renal disease (ESRD), accounting for approximately 69% of all renal replacement therapies and 89% of all dialysis.
- Trial name
- HDRRFI-NIRS (NCT06243900)
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Yuanjun Yang
Renal Insufficiency, Chronic
Safety and Efficacy of Zemplar Capsule in Reducing Serum iPTH Levels in Chronic Kidney Disease Subjects (Three Times Weekly)
The objective of this study is to determine whether paricalcitol is safe and effective compared to placebo in reducing elevated serum PTH levels in patients with chronic kidney disease.
- Trial name
- NCT00048451
- Testing
- paricalcitol
- Where
- 19 sites in United States, Poland
- Volunteers
- 68 people
- Sponsor
- Abbott
Chronic Kidney Disease
Efficacy and Safety of Volenrelaxin in Adults With Chronic Kidney Disease
The main purpose of this study is to investigate the efficacy and safety of Volenrelaxin in adults with Chronic Kidney Disease. The study will last about 24 weeks.
- Trial name
- NCT06598631
- Testing
- Volenrelaxin
- Where
- 35 sites in United States, Australia and 3 more
- Sponsor
- Eli Lilly and Company
Chronic Renal Failure, Anaemia
Study of Erythropoietin (EPO) Administration Schedule
The purpose of this study is to compare the hemoglobin and hematocrit variability between once and three times weekly erythropoietin therapy for the anemia in patients with maintenance dialysis.
- Trial name
- NCT01111630
- Testing
- recomon (Epoetin Beta)
- Where
- South Korea
- Volunteers
- 60 people
- Sponsor
- JW Pharmaceutical
Chronic Kidney Disease, End-stage Renal Disease
A Randomized Trial to Reduce the Disparity in Live Donor Kidney Transplantation
The main purpose of this study is to learn which educational method is most helpful to patients and their family members when they consider whether to pursue live donor kidney transplantation.
- Trial name
- NCT00785265
- Testing
- Group-Based (GB) Intervention, Home-Based (HB) Intervention
- Where
- United States
- Volunteers
- 164 people
- Sponsor
- Beth Israel Deaconess Medical Center
End Stage Renal Disease, Chronic Kidney Disease
Palm Tocotrienols in Chronic Hemodialysis (USA)
Patients undergoing chronic hemodialysis are at increased risk for cardiovascular disease, attributed in part to increased oxidative stress, inflammation and dyslipidemia.
- Trial name
- PATCH (NCT02358967)
- Testing
- TRF (Tocotrienol-rich-fraction)
- Where
- United States
- Volunteers
- 280 people
- Sponsor
- Wayne State University
Chronic Kidney Disease
REVEAL-CKD: Prevalence and Consequences of Undiagnosed Chronic Kidney Disease
This is a retrospective, multinational, non-interventional, observational study. A series of cohort studies will be conducted to assess the prevalence of undiagnosed stage 3 CKD in each region.
- Trial name
- REVEAL-CKD (NCT04847531)
- Where
- 13 sites in United States, Australia and 9 more
- Volunteers
- 1,006,361 people
- Sponsor
- AstraZeneca
Risk Factors, Renal Progression
P-cresol: Correlation With Glomerular Filtration Rate and Outcome in Chronic Kidney Disease
End-stage renal disease is a global epidemia with an estimated incidence of 7% per year and high morbidity-mortality rate. Early detection of chronic kidney disease (CKD) and intervention for CKD complication is important to…
- Conditions
- Risk Factors, Renal Progression, Death
- Trial name
- NCT00888030
- Testing
- there are no interventions currently listed for this study
- Where
- Taiwan
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Chronic Kidney Diseases, Blood Pressure
Nephrocare mHealth Project: Telemonitoring of Blood Pressure
The Nephrocare mHealth project supports patients with Chronic Kidney Disease with a mobile application and telemonitoring. The application includes the follow-up of blood pressure.
- Trial name
- Nephrocare (NCT03708666)
- Testing
- Telemonitoring of blood pressure
- Where
- Belgium
- Volunteers
- 79 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Kidney Disease, Kidney Transplant
Strategies to Transform Kidney Care and Improve Pursuit of Transplant
Approximately 15% of the U.S. population has chronic kidney disease, and ~700,000 patients are in full kidney failure also called end-stage kidney disease (ESKD).
- Conditions
- Kidney Disease, Kidney Transplant, Deceased Donor Kidney Transplant, Living Donor Kidney Transplantation
- Trial name
- NCT07794631
- Testing
- Digital Health Integration, Training for Early Transplant Access and Support, Kidney Health Mobile Health (mHealth) Application
- Where
- United States
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- The Methodist Hospital Research Institute
Type 2 Diabetes Mellitus, Chronic Kidney Disease
Extended Release Exenatide Versus Placebo In Diabetic Patients With Type 4 Cardiorenal Syndrome
Among adult individuals with type 2 diabetes mellitus and at risk for heart failure with impaired relaxation of the heart mildly reduced kidney filtration function (Type 4 cardiorenal syndrome) this trial will evaluate the…
- Conditions
- Type 2 Diabetes Mellitus, Chronic Kidney Disease, Left Ventricular Diastolic Dysfunction
- Trial name
- NCT02251431
- Testing
- BYDUREON
- Where
- United States
- Volunteers
- 57 people
- Sponsor
- Baylor Research Institute