Clinical trials: Kidney Failure,Chronic
Anemia of Chronic Kidney Disease
Mass Balance Study of JTZ-951 in Subjects With End-stage Renal Disease on Hemodialysis
A mass balance study to determine the routes and rates of elimination of radioactivity, to determine total radioactivity in plasma and whole blood over time and compare levels to JTZ-951 and drug-derived entities in plasma and to…
- Trial name
- NCT02805244
- Testing
- JTZ-951, 14C-JTZ-951
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Shionogi Inc.
Chronic Kidney Disease, Constipation
Effects of Constipation Treatment in Chronic Kidney Disease: A Pilot Feasibility Trial
Constipation is one of the most prevalent gastrointestinal disorders in patients with chronic kidney disease (CKD) and has been associated with their adverse kidney and cardiovascular outcomes; however, little is known about the…
- Trial name
- NCT06123195
- Testing
- Constipation treatment
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- University of Tennessee
Chronic Renal Failure
Cost Utility Analysis of Erythropoietin for Anemia Treatment in Hemodialysis Patients
To study the cost utility analysis of Erythropoietin (EPO) for maintaining the different hemoglobin (Hb) target levels in anemic hemodialysis patient in routine clinical practice.
- Trial name
- CUAEPO (NCT01049711)
- Testing
- erythropoietin
- Where
- Thailand
- Volunteers
- 152 people
- Sponsor
- Mahidol University
End Stage Renal Disease, Pruritus
Evaluating the Effect of Cromolyn Sodium in Uremic Pruritus
Pruritus is a major disorder among the skin derangements in advanced renal failure. Recent information suggests that interactions between dermal mast cells and distal ends of nonmyelinated C fibers may be important in the…
- Trial name
- NCT00745199
- Testing
- cromolyn sodium
- Where
- Iran
- Volunteers
- 62 people
- Sponsor
- Shiraz University of Medical Sciences
Renal Failure
Determination of a Profile of Patients with Renal Failure to Be Supported As a Priority in the Care Pathway in Order to Avoid Emergency Hospitalizations.
The purpose of this study is to map the population of stage 4 and 5 kidney failure patients followed in consultation by the CHSF nephrology team and to determine the factors associated with recurrent hospitalizations.
- Trial name
- DETERPROFIPA (NCT06041737)
- Testing
- consultation
- Where
- France
- Volunteers
- 405 people
- Sponsor
- Centre Hospitalier Sud Francilien
Chronic Kidney Disease, Heart Failure With Reduced Ejection Fraction (HFrEF)
Single and Twice-daily Dosing of Ramipril on Renal Function in Chronic Kidney Disease Patients With Reduced Ejection Fraction Heart Failure
This study compares the effects of once-daily versus twice-daily ramipril dosing on renal function in chronic kidney disease (CKD) patients with heart failure with reduced ejection fraction (HFrEF).
- Trial name
- NCT07259512
- Testing
- Ramipril
- Where
- Indonesia
- Volunteers
- 80 people
- Sponsor
- Evi Liliek Wulandari
Chronic Kidney Diseases, Cachexia
CKD Cachexia and Gut Microbiome
Cachexia is common in patients with chronic kidney disease (CKD) and is associated with increased morbidity and mortality. Cachexia is a complex syndrome, in which inflammation and retention of uremic toxins are two main…
- Trial name
- DYNAMICA (NCT06986265)
- Testing
- Collection of clinical data and biological sampling
- Where
- 2 sites in Belgium
- Volunteers
- 157 people
- Sponsor
- Université Catholique de Louvain
Chronic Kidney Disease(CKD), Proteinuria
Beneficial Effect of Amiloride on Progression of Chronic Kidney Disease
This is a randomized, placebo-controlled, double-blinded crossover trial testing the effects of amiloride in patients with chronic kidney disease (CKD) and proteinuria.
- Trial name
- A-CKD (NCT06923709)
- Testing
- amiloride
- Where
- Denmark
- Volunteers
- 40 people
- Sponsor
- Odense University Hospital
Diabete Type 1, Chronic Kidney Disease
Breakthrough - T1DM and Chronic Kidney Disease
Single arm- subject treated with Tegoprubart and everolimus. The purpose of this research is to gather information on the safety and effectiveness of investigational regimen containing 2 experimental components: An…
- Trial name
- NCT07592000
- Testing
- Tegoprubart, Islet Cell Transplant
- Where
- 2 sites in United States
- Volunteers
- 10 people
- Sponsor
- University of Chicago
Hypogonadism
Testosterone Replacement in Renal Failure
The purpose of this trial is to evaluate the effect of testosterone replacement in men with renal failure (on dialysis) who also have low testosterone.
- Trial name
- NCT02712944
- Testing
- Testosterone, Saline
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Texas Tech University Health Sciences Center
Renal Insufficiency
Factors Related to Geographical Variation in the Incidence of End-stage Renal Failure: An Analysis in 5 French Regions
The REIN registry highlights significant disparities in the incidence of end-stage renal disease (ESRD) between regions, especially in the North East of France.
- Trial name
- VIgIE (NCT02849964)
- Where
- 4 sites in France
- Volunteers
- 6,835 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
End-stage Kidney Disease
Kinetics of Extracellular Vesicles in Hemodialysis
The aim of this observational study is to gain insight into the kinetics of extracellular vesicles (EVs), derived from both in- (i.e.
- Trial name
- NCT05957146
- Testing
- Routine hemodialysis
- Where
- Netherlands
- Volunteers
- 6 people
- Sponsor
- Amsterdam UMC, location VUmc
Dialysis, Chronic Kidney Disease
Next Generation Advanced Insulin Delivery System in Adults With Diabetes and Advanced Renal Disease
The goal of this this randomized, clinical trial is to test an automated insulin delivery system (AID) in people with type 1 or type 2 diabetes who are on hemodialysis, peritoneal dialysis, or have advanced chronic kidney disease…
- Conditions
- Dialysis, Chronic Kidney Disease, Diabetes Mellitus, Type 2, Diabetes Mellitus, Type 1
- Trial name
- NCT06330194
- Testing
- 2nd Generation Automated Insulin Delivery (AID) system
- Where
- Denmark
- Volunteers
- 15 people
- Sponsor
- Steno Diabetes Center Copenhagen
End-stage Renal Disease, Kidney Failure, Chronic
Safety and Efficacy of a Vascular Prosthesis for Hemodialysis Access in Patients With End-Stage Renal Disease
The purpose of this study is to assess the safety and efficacy of a novel, tissue-engineered vascular prosthesis, the Human Acellular Vascular Graft, HAVG.
- Trial name
- NCT01840956
- Testing
- HAVG
- Where
- 3 sites in United States
- Volunteers
- 20 people
- Sponsor
- Humacyte, Inc.
Obesity, ESRD
Bariatric Surgery for ESRD Patients vs Control
This study will address a true clinical problem by developing a risk/benefit analysis for rapid surgical weight loss in the ESRD population.
- Trial name
- NCT00580762
- Testing
- Roux-en-y gastric bypass (RYGB)
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Yale University
Chronic Kidney Diseases
Telemedicine for Home-based Management of Patients With Chronic Kidney Diseases and Comorbidities (NET-2018-12367206)
This project is aimed to analyze the current models and to design innovative strategies to improve quality of care and optimise resource utilization of telemedicine (TM) in home-based management for the global care of patients…
- Trial name
- Telemechron (NCT05906927)
- Where
- Italy
- Volunteers
- 8 people
- Sponsor
- Azienda USL Toscana Nord Ovest
Chronic Kidney Diseases, Cardiovascular Diseases
Assessment of Protein Modification in Chronic Kidney Disease - Selected Clinical and Biochemical Aspects
The studies included the effect of chronic kidney disease advancement on the accumulation of oxidative stress markers in plasma. In patients with end-stage renal disease, the effect of replacement therapy was also assessed.
- Conditions
- Chronic Kidney Diseases, Cardiovascular Diseases, Dialysis; Complications
- Trial name
- NCT04939870
- Testing
- Biochemical parameters evaluation
- Where
- Poland
- Volunteers
- 195 people, healthy volunteers welcome
- Sponsor
- Poznan University of Medical Sciences
Oxygen Saturation and the Relationship to Other Cardiac Variables, Maintenance Hemodialysis
Hypoxemia in Maintenance Hemodialysis Patients
Previous research has shown that many patients with kidney failure undergoing chronic hemodialysis (HD) have a very low venous oxygen concentration, which may further decrease during dialysis treatments.
- Conditions
- Oxygen Saturation and the Relationship to Other Cardiac Variables, Maintenance Hemodialysis, Kidney Failure, Chronic
- Trial name
- NCT03045796
- Testing
- Oxygen Saturation measured by WristOx
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Illinois at Urbana-Champaign
HFrEF - Heart Failure With Reduced Ejection Fraction, Chronic Kidney Disease
Swedish Cardiac And Renal Failure Study-1
Previous studies have shown that patients with heart failure with reduced pumping function and preserved kidney function experience improved symptoms, longer survival, and fewer hospitalizations when treated with medications such…
- Trial name
- SCARF-1 (NCT07029503)
- Testing
- Eplerenone
- Where
- Sweden
- Volunteers
- 40 people
- Sponsor
- Karolinska Institutet
End-stage Renal Disease
Propaten Randomized Investigation on Cost-benefit and Efficacy
The purpose for this study is to evaluate the patency and outcomes of conventional and heparin anticoagulant bonded arteriovenous grafts in patients with end stage renal disease.
- Trial name
- PRICE (NCT01601873)
- Testing
- PROPATEN, Standard Graft
- Where
- 5 sites in United States
- Volunteers
- 103 people
- Sponsor
- The University of Texas Health Science Center, Houston
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