Clinical trials: Kidney Failure,Chronic
Chronic Kidney Disease, Secondary Hyperparathyroidism
Safety Study of CTA018 Injection to Treat Stage 5 Chronic Kidney Disease
This study will investigate the levels of CTA018 in the body over time (pharmacokinetics, PK) in patients with chronic kidney disease (CKD) and secondary hyperparathyroidism (SHPT), undergoing regular hemodialysis.
- Conditions
- Chronic Kidney Disease, Secondary Hyperparathyroidism, Chronic Renal Insufficiency, Chronic Renal Failure
- Trial name
- NCT00742716
- Testing
- CTA018 Injection
- Where
- 12 sites in United States, Canada
- Volunteers
- 41 people
- Sponsor
- OPKO IP Holdings II, Inc.
Chronic Kidney Disease
Renal Denervation in Patients With Chronic Kidney Disease
People with hypertension are at a higher risk for cardiovascular disease and death so it is important to lower blood pressure to normal levels as quickly as possible.
- Trial name
- NCT01832233
- Testing
- Renal Denervation
- Where
- Canada
- Volunteers
- 26 people
- Sponsor
- Saskatchewan Health Authority - Regina Area
Chronic Kidney Diseases
A Delphi Survey for Key Stakeholders to Identify Priority Self-management Outcomes for Chronic Kidney Disease
The purpose of this Delphi study is to identify priority outcomes for self-management in earlier (non-dialysis) stages of CKD from the perspectives of different stakeholder groups in the UK.
- Trial name
- NCT05991726
- Testing
- Other: Survey
- Where
- United Kingdom
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- University of Leicester
Renal Insufficiency, Chronic
Metformin in Moderate and Severe Renal Failure (CKD 3-4): A Follow-up Study
To validate on the mid-term in moderate and severe renal failure (CKD 3-4) a nomogram to adapt a fixed metformin daily posology according to renal function on the basis of the first short-term study made by the investigators.
- Trial name
- METsuiviIRC (NCT02848508)
- Testing
- Metformin
- Where
- France
- Sponsor
- Centre Hospitalier Universitaire, Amiens
End-stage Renal Disease
End-Stage Renal Disease Intra-dialysis Lifestyle Education Study
The purpose of this study is to compare the effects of intra-dialysis yoga to an educational program among patients with end-stage renal disease.
- Trial name
- END-IDLE (NCT02361268)
- Testing
- Intradialysis-yoga, Educational program
- Where
- United States
- Volunteers
- 67 people
- Sponsor
- Vanderbilt University Medical Center
Chronic Kidney Diseases, Hyperkalemia
Potassium Correction for RAAS Optimization in Chronic Kidney Disease
The goal of this placebo-controlled, double-blinded cross-over trial is to test whether patiromer, compared with placebo, better enables up-titration of RAAS-blocker treatment in patients with chronic kidney disease stage 3b/4.
- Conditions
- Chronic Kidney Diseases, Hyperkalemia, Hypertension
- Trial name
- PROMISE (NCT06256991)
- Testing
- Patiromer 8400 MG [Veltassa]
- Where
- Netherlands
- Volunteers
- 44 people
- Sponsor
- University Medical Center Groningen
ESRD
Fabry Disease Screening in ESRD Patients in West of France
Screening of Fabry disease in end-stage renal disease (ESRD) patients on dialysis or transplant in west of France.
- Trial name
- SNOUFY (NCT02719249)
- Testing
- Dried blood spot test
- Where
- France
- Volunteers
- 500 people
- Sponsor
- Rennes University Hospital
Chronic Kidney Diseases, Hypertension
Interactive Computer-adaptive Chronic Kidney Disease Education Program
The goal of this pilot clinical trial is to evaluate a culturally tailored computerized education program in hospitalized African-American patients with advanced chronic kidney disease (CKD).
- Trial name
- ICCKD (NCT06364358)
- Testing
- Computerized CKD Education, Usual Hospital Care
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- University of Chicago
End Stage Renal Disease
Elbow Pain in Hemodialysis Patients and Its Effect on Daily Living Activities of the Patients
The study will include the patients undergoing hemodialysis.
- Trial name
- NCT04188210
- Testing
- Presence of elbow pain in patients with end stage renal disease
- Where
- Turkey (Türkiye)
- Volunteers
- 135 people
- Sponsor
- Namik Kemal University
Chronic Renal Disease
Residual Renal Function Preservation in Peritoneal Dialysis Patients
Aldosterone blockade is useful in preserving residual renal function in patients on PD.The long term efficacy of dual blockade of the RAAS is better than monotherapy.
- Trial name
- NCT02190318
- Testing
- Losartan, spirolactone, blank control
- Where
- China
- Volunteers
- 96 people
- Sponsor
- Second Xiangya Hospital of Central South University
Patients With End Stage Renal Disease on Hemodialysis
Effect of Plasma Sodium Concentration on Blood Pressure Regulators During Hemodialysis
Intradialytic hypotension (IDH) is a frequent and serious complication that may occur during hemodialysis treatment. The investigators and others have shown that the Hemocontrol biofeedback system is associated with improved…
- Trial name
- NCT03578510
- Testing
- Hemocontrol hemodialysis, Standard hemodialysis
- Where
- Netherlands
- Volunteers
- 29 people
- Sponsor
- University Medical Center Groningen
Cardiovascular Diseases, Heart Diseases
Risk Factors for CV Disease in a Dialysis Cohort
To investigate whether traditional risk factors and novel risk factors predict higher risk of atherosclerotic cardiovascular disease (ASCVD) in a prospective study of incident dialysis patients.
- Conditions
- Cardiovascular Diseases, Heart Diseases, Atherosclerosis, Kidney Failure, Chronic
- Trial name
- NCT00006297
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Chronic Kidney Disease
Effect of Phosphate Binders on Markers of Vascular Health in Chronic Kidney Disease Stages 3 and 4
Chronic kidney disease (CKD) patients often have high levels of a substance called fibroblast growth factor-23 (FGF-23), a phosphorus excreting hormone, which has been related to heart disease.
- Trial name
- NCT01277497
- Testing
- Sevelamer carbonate, Calcium acetate
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Albany College of Pharmacy and Health Sciences
End-stage Renal Disease
The Microcirculation, Dialysis Modality and Sequestered Salt
The aim of this clinical trial is to investigate the effect of 5 different dialysis treatments (combinations of dialysis mode and dialysis fluid sodium content) on the microcirculation (MC) and sequestered sodium content (SSC) in…
- Trial name
- MIMOSA (NCT06327750)
- Testing
- Hemodialysis (DNa = PNa), Hemodialysis (DNa<PNa), Hemodialysis after isolated ultrafiltration (DNa=PNa)
- Where
- 2 sites in Netherlands
- Volunteers
- 23 people
- Sponsor
- Amsterdam UMC, location VUmc
Stage 5 Chronic Kidney Disease
Impact of a Multidisciplinary Intensive Management Clinic on Outcomes in Multi-Ethnic Asian Incident Hemodialysis Patients
Patients with end-stage renal disease are most vulnerable in the early months following hemodialysis (HD) initiation. Data from the United States Renal Data System and Singapore Renal Registry showed high mortality rates in the…
- Trial name
- NCT01509690
- Testing
- Multidisciplinary, intensive and collaborative care
- Where
- Singapore
- Volunteers
- 150 people
- Sponsor
- National University of Singapore
Chronic Kidney Disease, Type 2 Diabetes
A Glomerular Filtration Rate (GFR) Measuring Study of RTA 402 in Chronic Kidney Disease (CKD) Patients With Type 2 Diabetes Mellitus
A Phase 2 glomerular filtration rate (GFR) measuring study of RTA 402 in Chronic kidney disease (CKD) patients with type 2 diabetes mellitus.
- Trial name
- NCT01572610
- Testing
- RTA 402
- Where
- Japan
- Volunteers
- 11 people
- Sponsor
- Kyowa Kirin Co., Ltd.
Chronic Renal Insufficiency
Intensive Versus Standard Hemodialysis CVC Dysfunction Protocol
Central venous catheters (CVCs) are used for vascular access by approximately 56% of our 380 hemodialysis (HD) patients at the Capital Health Renal Program.
- Trial name
- NCT02474810
- Testing
- Alteplase
- Where
- Canada
- Volunteers
- 35 people
- Sponsor
- Nova Scotia Health Authority
End Stage Renal Disease
Cognitive Impairment and Imaging Correlates in End Stage Renal Disease
This is an observational cohort to understand cognitive impairment in end stage renal disease before and after a kidney transplant.
- Trial name
- NCT01883349
- Testing
- Kidney Transplant, No kidney transplant
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- University of Kansas Medical Center
End Stage Renal Failure
Physical and Psychological Profiles Associated With Patient's Preference for ESRD Treatment
Highlighting the relationship between psychological and physical profiles and patient's preference to better understand the patient's treatment preference and improve the information provided.
- Trial name
- NCT01834755
- Testing
- Evaluation of psychological phenotype
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Diabetes Mellitus, End-Stage Renal Disease
Continuous Glucose Monitoring in People With Diabetes on Dialysis
Continuous glucose monitoring is a sensor, which monitors glucose levels continuously throughout the day. In people with diabetes, especially those treated with insulin, this sensor helps guide the amount of treatment (such as…
- Trial name
- RECORD (NCT06657508)
- Where
- United Kingdom
- Volunteers
- 40 people
- Sponsor
- University of Nottingham
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