Clinical trials: Kidney Failure,Chronic
End Stage Renal Disease on Dialysis
Home-based vs Intradialysis Exercise Guided by Nursing Staff
Participants will be randomized either to home-based exercise or to intradialysis exercise guided by nurses of the renal unit. The programs will last 16 weeks.
- Trial name
- HoBIDnurse (NCT04051515)
- Testing
- Intradialysis exercise training, Home-based exercise training
- Where
- 7 sites in Belgium, Greece and 2 more
- Volunteers
- 70 people
- Sponsor
- Cardenal Herrera University
End Stage Kidney Disease
Alio WEAR Study: Long-term Wear of the Alio Platform
The WEAR study is long-term interventional study designed to evaluate patient and clinician use of the Alio platform, per its FDA cleared indications.
- Trial name
- NCT06056739
- Testing
- Alio platform
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- Alio, Inc.
End-stage Renal Disease
Network Interventions to Reduce Disparities in Living Kidney Donation
For this current phase of the larger project, the investigators will survey transplant candidates as well as the participants family and friends to understand the barriers to volunteering and evaluation.
- Trial name
- NCT05255757
- Testing
- Script Intervention, Search Intervention
- Where
- 2 sites in United States
- Volunteers
- 164 people
- Sponsor
- Penn State University
Chronic Renal Failure
Effect of Hydration With Sodium Bicarbonate for Long-Term Clinical Outcomes in Patients With Chronic Kidney Disease Undergoing an Emergent Coronary Procedure
This study is to evaluate the efficacy of sodium bicarbonate plus N-acetylcysteine for the prevention of contrast-induced nephropathy.
- Trial name
- NCT00716001
- Testing
- N-acetylcysteine
- Sponsor
- Osaka General Medical Center
End Stage Renal Disease, Renal Transplantation
Comparisone of Iminoral Versus Neoral in Prevention of Acute Rejection in Renal Transplantation
Cyclosporine is the key drug in organ transplantation. In Iran the investigators have more than 2500 new renal transplantation each year and because of this the government pay a huge amount of money for subsiding the imported…
- Trial name
- NCT00656695
- Testing
- Iminoral, Neoral
- Where
- Iran
- Volunteers
- 208 people
- Sponsor
- Imam Khomeini Hospital
Kidney Disease, Kidney Transplantation
Role of Donor Genetics and Recipient Genetics in Kidney Transplant Outcomes
Background: Genetic variation in a particular chromosome is a major contributor to the increased risk for kidney disease that is common in people of African descent, although the specific gene, mutations, and other aspects of the…
- Conditions
- Kidney Disease, Kidney Transplantation, Kidney Failure, Chronic
- Trial name
- NCT01143532
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Renal Failure Chronic Requiring Hemodialysis
Continuous Soluble Ferric Pyrophosphate (SFP) Iron Delivery Via Dialysate in Hemodialysis Patients
The purpose of this study is to confirm the safety and efficacy of Soluble Ferric Pyrophosphate (SFP) dialysate solution in maintaining iron delivery for erythropoiesis in anemic adult patients with chronic kidney disease (CKD)…
- Trial name
- CRUISE 1 (NCT01320202)
- Testing
- Soluble Ferric Pyrophosphate (SFP), Standard dialysate
- Where
- 47 sites in United States, Puerto Rico
- Volunteers
- 305 people
- Sponsor
- Rockwell Medical Technologies, Inc.
End Stage Kidney Disease
Duke APOL1 Research Biorepository
The Duke ApoL1 Nephropathy Biorepository aims to address needs within non-diabetic kidney failure research by utilizing existing and, when necessary, developing new infrastructure to support the consent of patients and the…
- Trial name
- DARB (NCT04160507)
- Testing
- Biorepository
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Duke University
End-Stage Renal Disease
REFLEXOLOGY AND SLEEP HYGIENE IN HEMODIALYSIS TREATMENT (HD)
Sleep problems are common in people undergoing dialysis treatment due to kidney failure. Methods other than medication can be used to improve this condition.
- Trial name
- HD (NCT07518628)
- Testing
- Reflexology
- Where
- 2 sites in Cyprus
- Volunteers
- 60 people
- Sponsor
- Kibrıs Aydin Üniversitesi
Kidney Insufficiency, Chronic
Cognitive Impairment in Kidney Disease
An increasing number of Veterans are anticipated to develop chronic kidney disease (CKD) and require hemodialysis (HD) treatments as the Veteran population ages.
- Trial name
- NCT00905619
- Where
- United States
- Volunteers
- 117 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
End-Stage Renal Disease
Urgent-start Peritoneal Dialysis in ESRD Patients：A Multi-center Study
Within the last decade, urgent-start peritoneal dialysis(PD) has gained considerable interest amongst nephrologists. Several publications have provided assurances that urgent-start PD is indeed feasible and can serve patients…
- Trial name
- NCT02946528
- Testing
- urgent-start peritoneal dialysis catheter, central venous catheter
- Where
- China
- Volunteers
- 116 people
- Sponsor
- RenJi Hospital
End Stage Kidney Disease
Potassium Containing Salt-Substitute in Hemodialysis-Dependent End Stage Kidney Disease
16 individuals with hemodialysis-dependent end stage kidney disease will receive 16 days of a potassium-containing salt-substitute and 16 days of standard table salt in random order.
- Trial name
- NCT05558267
- Testing
- Standard Table Salt, Salt Substitute
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- NYU Langone Health
Chronic Kidney Failure, HIV Infection
Kidney Transplant for HIV-Infected Patients in Renal Failure
This study will examine the safety and effectiveness of renal (kidney) transplantation for HIV-infected patients with end-stage renal disease (kidney failure).
- Trial name
- NCT00009009
- Testing
- immunosuppressive regimen designed to complement HAART
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Chronic Kidney Disease
Iplasma IL6, Procalcitonin and VEGF and Dialysate Level in CAPD Patients
The aim of study was to evaluated the correlation between plasma levels, dialysate appearance rate of VEGF, inflammatory cytokines (IL- 6, procalcitonin) and PSTR, dialysis adequacy in CAPD patients.
- Trial name
- NCT02881892
- Testing
- Measure plasma and dialysate level of IL-6, procalcitonin and VEGF
- Where
- Thailand
- Volunteers
- 26 people
- Sponsor
- Bangkok Metropolitan Administration Medical College and Vajira Hospital
Chronic Kidney Disease, Depression
Chronic Kidney Disease Antidepressant Sertraline Trial
This is a randomized double-blinded placebo-controlled trial to see if treatment with sertraline as compared with placebo tablets will improve depression symptoms in patients with chronic kidney disease who have not yet started…
- Trial name
- CAST (NCT00946998)
- Testing
- Sertraline
- Where
- 2 sites in United States
- Volunteers
- 201 people
- Sponsor
- VA Office of Research and Development
Hypertension, Chronic Kidney Disease
Safety and Tolerability of Valsartan in Children 6 to 17 Years of Age
The purpose of this study is to assess the long-term safety and tolerability profile of valsartan and valsartan-based treatments in children with hypertension, with or without chronic kidney disease.
- Trial name
- NCT01365481
- Testing
- Valsartan, amlodipine, Hydrochlorothiazide
- Where
- 28 sites in Colombia, Finland and 8 more
- Volunteers
- 150 people
- Sponsor
- Novartis Pharmaceuticals
Chronic Periodontitis, End Stage Renal Disease
Novel PAradigm to Improve Inflammatory Burden in ESRD (rePAIR): A Pilot and Feasibility Randomized Controlled Trial
The goal of this project is to assess repeated and ongoing oral care and the way it may affect inflammation and quality of life in hemodialysis patients.
- Trial name
- rePAIR (NCT03241511)
- Testing
- Test
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- UConn Health
Proteinuria, Diabetic Nephropathy
FGF-23 and Endothelial Dysfunction in Diabetic Proteinuric Patients
There is no data about the effects of Renin angiotensin system blockage (RAS) on FGF23 and ADMA levels in diabetic patients with proteinuria.
- Conditions
- Proteinuria, Diabetic Nephropathy, Chronic Kidney Disease
- Trial name
- NCT01703234
- Testing
- Ramipril
- Where
- Turkey (Türkiye)
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Gulhane School of Medicine
End Stage Renal Disease, Hemodialysis
The Effects of Intradialytic Exercise in Hemodiafiltration Patients
Low physical activity is associated with in hemodialysis and hemodiafiltration (HDF) patients. Previous studies showed the benefits of intradialytic exercise for improvement of physical fitness and hemodialysis adequacy.
- Conditions
- End Stage Renal Disease, Hemodialysis, Sedentary Lifestyle
- Trial name
- NCT03353844
- Testing
- Intradialytic exercise
- Where
- Thailand
- Volunteers
- 12 people
- Sponsor
- Chulalongkorn University
End-stage Renal Disease, Renal Replacement Therapy
Can High Convection Volumes be Achieved in Each Patient During Online Post-dilution Hemodiafiltration?
Two recent randomized controlled trials (RCT) on online hemodiafiltration (HDF) did not show a treatment effect on patient survival when compared with low- or high-flux hemodialysis.
- Conditions
- End-stage Renal Disease, Renal Replacement Therapy, Hemodiafiltration, Convection Volume
- Trial name
- NCT01877499
- Testing
- Optimization of HDF key parameters
- Where
- 7 sites in Netherlands
- Volunteers
- 86 people
- Sponsor
- Amsterdam UMC, location VUmc
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