Clinical trials: Kidney Functional
Chronic Kidney Diseases
A Study to Explore the Renal Safety of Visipaque Injection 320 mgI/mL in Patients With Chronic Kidney Disease
This parallel-group, randomized, placebo-controlled study will examine the incidence and severity of acute kidney injury (AKI) in patients with chronic kidney disease (CKD) stage III/IV following an i.v.
- Trial name
- NCT03119662
- Testing
- Visipaque
- Where
- 29 sites in United States, Belgium and 4 more
- Volunteers
- 4 people
- Sponsor
- GE Healthcare
Chronic Disease, Type 2 Diabetes Mellitus (T2DM), Obesity, Overweight
Truway Diagnostic Tools in Primary Care
This study evaluates the effectiveness of Truway Health-sourced portable diagnostic devices, including ultrasound and blood glucose monitors, in early detection of chronic conditions in outpatient primary care settings.
- Conditions
- Chronic Disease, Type 2 Diabetes Mellitus (T2DM), Obesity, Overweight, Hypertension, Cardiovascular Disease Acute
- Trial name
- TruDxPC (NCT07209527)
- Testing
- Truway Portable Ultrasound Device, Truway Blood Glucose Monitor, Standard Oral Hypoglycemic Agent
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Truway Health, Inc.
Severe Hypertriglyceridemia
Study to Evaluate the Efficacy and Safety of K-877 in Adult Patients With Fasting High Triglyceride Levels and Normal Renal Function
The purpose of this study is to evaluate the efficacy and safety of K-877 in adult patients with fasting high triglyceride levels ≥500 mg/dL and <2000 mg/dL and normal renal function.
- Trial name
- NCT03001817
- Testing
- K-877, Fenofibrate
- Where
- 220 sites in United States, Belarus and 7 more
- Volunteers
- 551 people
- Sponsor
- Kowa Research Institute, Inc.
Renal Impairment
Evaluate PK and Safety of Proellex® in Females With Various Stages of Impaired Renal Function and Healthy Females
PK and safety profile of Proellex® in females with various stages of impaired renal function
- Trial name
- NCT00787618
- Testing
- 50 mg Proellex
- Where
- 4 sites in United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Repros Therapeutics Inc.
Chronic Kidney Diseases
Sex Hormone and Vascular Function in Women With CKD
The risk of cardiovascular disease (CVD) is significantly elevated in patients with chronic kidney disease (CKD). Notably, women with CKD commonly experience menstrual disturbances induced by CKD, which may contribute to impaired…
- Trial name
- NCT05471518
- Testing
- No intervention
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- University of Colorado, Denver
End Stage Renal Disease
Combined Resistance and Aerobic Exercise is Better Than Resistance Training Alone to Improve Functional Performance of Hemodialysis Patients - Results of a Randomized Trial
This is a randomized trial with participants recruited from one dialysis unit of a Brazilian university hospital. Hemodialysis patients were assigned to receive the resistance exercise combined with an aerobic training or the…
- Trial name
- NCT01076881
- Testing
- exercise training
- Where
- Brazil
- Volunteers
- 26 people
- Sponsor
- Universidade Católica de Pelotas
Hyperuricemia, Gout
Effect of Quercetin Supplements on Healthy Males: a Four-Week Randomized Cross-Over Trial
The purpose of this study was to test the effect of chronic consumption of Quercetin 500 mg tablets on blood uric acid and other biomarkers in adult males.
- Conditions
- Hyperuricemia, Gout, Kidney Calculi, Diabetes
- Trial name
- NCT01881919
- Testing
- Treatment, Control
- Where
- United Kingdom
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University of Leeds
Polycystic Ovary Syndrome, Urine Albumin \(UAlb\)
Urine Albumin/Creatinine Ratio and Renal Function Differences in Phenotypes of Polycystic Ovary Syndrome.
Since there are different metabolic effects in different phenotypes of polycystic ovary syndrome (PCOS); in this study; the investigators aimed to investigate whether there is a difference between glomerular filtration rate…
- Conditions
- Polycystic Ovary Syndrome, Urine Albumin \(UAlb\), Urine Creatinine \(UCr\), Glomerular Filtration Rate
- Trial name
- NCT07441811
- Where
- Turkey (Türkiye)
- Volunteers
- 300 people
- Sponsor
- Uşak University
Chronic Kidney Disease, Bariatric Surgery Candidate
Weight Loss in Obese Kidney Disease Patients After Bariatric Surgery
This study is designed as a prospective, single-center, longitudinal and analytical study on the effect of bariatric surgery in obese patients with chronic kidney disease (CKD).
- Trial name
- NCT02644928
- Where
- Spain
- Volunteers
- 12 people
- Sponsor
- Enrique Morales Ruiz, MD
Acute Renal Failure
Brief Title:Effect of a Preoperative Calorie Restriction on Renal Function After Cardiac Surgery
The aim of this study is to assess the effect of a diet prior to cardiac surgery on the common postoperative decline of renal function. Until now, there is no known drug or procedure to preserve the kidneys from this impairment.
- Trial name
- CR_KCH (NCT01534364)
- Testing
- calorie restriction
- Where
- Germany
- Volunteers
- 82 people
- Sponsor
- University of Cologne
Kidney Failure, Chronic, Renal Dialysis
Intradialytic Versus Home-Based Exercise in Female Hemodialysis Patients
This randomized controlled trial compared intradialytic exercise with home-based exercise in married female patients receiving maintenance hemodialysis.
- Trial name
- NCT07716436
- Testing
- Intradialytic Exercise, Home-Based Exercise
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Tanta University
Water Stress, Body Water Dehydration
Influence of Osmotic Stimulation of Vasopressin on Autonomic Function
The regulation of total body water that defines human hydration status is a complex and dynamic process. Current methods of assessing hydration status (e.g.
- Trial name
- NCT04233606
- Testing
- Hypertonic Saline, Normal Saline
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of North Carolina, Greensboro
Chronic Kidney Disease
The Role of Vitamin D in Immune Function in Patients With Chronic Kidney Disease (CKD) Stages 3 and 4.
Patients with chronic kidney disease (CKD) are commonly deficient in vitamin D, with low levels of both calcidiol (25 hydroxy vitamin D) and calcitriol (1,25-hydroxy vitamin D).
- Trial name
- NCT00749736
- Testing
- cholecalciferol, doxercalciferol
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Indiana University
ADPKD, Autosomal Dominant Polycystic Kidney Disease
ADPKD Alterations in Hepatic Transporter Function
This is a single center, comparative cohort study to investigate alterations in hepatic transporter function in subjects with autosomal dominant polycystic kidney disease (ADPKD) compared to healthy subjects and subjects with…
- Conditions
- ADPKD, Autosomal Dominant Polycystic Kidney Disease, Renal Disease
- Trial name
- NCT03717883
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Chronic Kidney Disease stage3, Chronic Kidney Disease stage4
Flywheel Exercise for CKD
Among Veterans, the prevalence of chronic kidney disease (CKD) is reported to be as high as 47.3% and a third higher than the general population. Muscle wasting and dysfunction have been identified as primary consequences of CKD.
- Trial name
- NCT03582982
- Testing
- Eccentric overload exercise
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Washington D.C. Veterans Affairs Medical Center
Physical Activity, Kidney Diseases
Effects of Exercise and Exercise Counselling in Hemodialysis Patients.
The aim of the study is to determine the effect of functional exercise and training counseling by kinesiotherapist in addition to the basic exercise program of cycling during dialysis on physical performance of dialysis patients.
- Conditions
- Physical Activity, Kidney Diseases, Kidney Failure, Chronic Kidney Diseases
- Trial name
- NCT03334123
- Testing
- Functional training and cycling, Cycling
- Where
- Slovenia
- Volunteers
- 86 people
- Sponsor
- University Medical Centre Ljubljana
Diabetes Mellitus Associated With Genetic Syndrome, Wolfram Syndrome
GLP Analogs for Diabetes in Wolfram Syndrome Patients
Wolfram syndrome, also referred to as DIDMOAD (diabetes insipidus, diabetes mellitus, optic atrophy and deafness) is a genetic syndrome characterized by beta-cell dysfunction and apoptosis leading to diabetes, neurodegeneration…
- Trial name
- NCT01302327
- Testing
- Exenatide
- Sponsor
- Hadassah Medical Organization
Delayed Function of Renal Transplant
Effects of the Use of "de Novo" Everolimus in Renal Tranplant Population
This is an open, randomized, single-center study. The selected patients will be first divided into two major groups according to the type of organ to be transplanted: standard criteria donor (SCD) or extended criteria (ECD)…
- Trial name
- NCT01663805
- Testing
- Everolimus
- Where
- 3 sites in Brazil
- Volunteers
- 80 people
- Sponsor
- MARIO ABBUD FILHO
Delayed Graft Function
TxAccess and Dd-cfDNA for Improved Care of Patients With Delayed Graft Function
This is a prospective multicenter nonrandomized pragmatic hybrid effectiveness-implementation study to test the effectiveness of TxAccess in improving time to renal recovery and immunologic outcomes in patients with delayed graft…
- Trial name
- NCT07825688
- Testing
- TxAccess, Donor-Derived Cell-Free DNA (dd-cfDNA)
- Volunteers
- 450 people
- Sponsor
- Duke University
Renal Insufficiency, Pharmacokinetics
A Single Dose Study Investigating the Elimination as Well as the Tolerability of PD 0332334 in Healthy Subjects as Compared to Patients With Impaired Kidney Function.
1. To investigate the effect of kidney function on the elimination of a single dose of PD 0332334 from the body. 2. To investigate the safety and tolerability of a single dose of PD 0332334 in patients with impaired kidney…
- Trial name
- NCT00721422
- Testing
- PD 0332334
- Where
- 2 sites in United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Pfizer
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