Clinical trials: Kidney Functional
Renal Impairment
Safety and Pharmacokinetics of Fluzoparib in Healthy Subjects and Those With Impaired Kidney Function
The primary objective is to evaluate pharmacokinetics of Fluzoparib and its main metabolite in subjects with impaired kidney function in comparison with healthy subjects, to develop dose recommendations for patients with renal…
- Trial name
- NCT05032235
- Testing
- Fluzoparib
- Where
- China
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Jiangsu HengRui Medicine Co., Ltd.
Cardiomyopathy, Heart Failure
The Impact of Pomegranate Extract on Chronic Cardiomyopathy Complicated by Renal Insufficiency (ImPrOVE): a Pilot Study
This blinded, controlled study will examine the impact of pomegranate polyphenol extract (POMx, from Pom Wonderful, LLC), 1000mg on cardiomyopathy in subjects with chronic renal insufficiency.
- Trial name
- ImPrOVE (NCT01102140)
- Testing
- POMx, pomegranate polyphenol extract, Sugar Pill
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- Jennifer Cowger , MD, MS
Chronic Renal Failure
Initiative for Patient Outcomes in Dialysis - Peritoneal Dialysis (PD) (IPOD-PD Study)
The aim of the study is to asses the hydration status of incident peritoneal dialysis (PD) patients and its evolution over a period of four years, independent of the PD treatment modality (APD or CAPD) and the PD solution type.
- Trial name
- IPOD-PD (NCT01285726)
- Testing
- Non-interventional study
- Where
- 134 sites in Austria, Belgium and 26 more
- Volunteers
- 1,092 people
- Sponsor
- Fresenius Medical Care Deutschland GmbH
Diabetes Mellitus, Type 2, Liver Diseases
Validate Smart Breath Analyzer as Screening Tool for Diabetic, Hepatic, Renal, Lung, and Other Metabolic Disorders
This is a prospective, multicentric, non-treatment study to build and validate a portable, non-invasive smart breath analyzer that can screen underlying health issues using exhaled breath.
- Conditions
- Diabetes Mellitus, Type 2, Liver Diseases, Kidney Diseases, Lung Diseases
- Trial name
- RESPYR-SBA (NCT07646015)
- Where
- India
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Respyr
Liver Transplantation
REnal Function in Liver Transplantation: Everolimus With Calcineurin Inhibitor (CNI)-Sparing sTrategy
The purpose of this study was, starting from the Italian clinical practice in liver transplantation, to optimize the immunosuppressive therapy, considering specific patient characteristics as alcoholic cirrhosis, hepatitis C…
- Trial name
- REFLECT (NCT02115113)
- Testing
- Everolimus, Tacrolimus
- Where
- 14 sites in Italy
- Volunteers
- 78 people
- Sponsor
- Novartis Pharmaceuticals
End Stage Renal Disease on Dialysis
Pulmonary Function Tests in Children and Adolescents With End Stage Renal Disease On Regular Hemodialysis
to study pulmonary function tests in children with ESRD on regular HD and its correlation with dialysis duration and other various risk factors
- Trial name
- NCT06106438
- Volunteers
- 40 people
- Sponsor
- Assiut University
Acupuncture Therapy, Hemodialysis Patients
Effect of Acupuncture on Hemodialysis Patients
The proposed randomized controlled trial (RCT) evaluated the effect of acupuncture treatment on the functional capacity (FC) and health-related quality of life (HRQoL) in stage 5 Chronic Kidney Disease (CKD) patients receiving…
- Conditions
- Acupuncture Therapy, Hemodialysis Patients, Quality of Life, Activities of Daily Living
- Trial name
- NCT05362643
- Testing
- Acupuncture
- Where
- Portugal
- Volunteers
- 60 people
- Sponsor
- Universidade do Porto
Renal Function Disorder, Postoperative Delirium
Conscious Sedation for Transcatheter Aortic Valve Implantation
Aortic valve stenosis is the heart valve disease with the highest prevalence among the elderly, and may lead to heart failure. Until recently, the only definitive treatment was surgical replacement (SAVR).
- Conditions
- Renal Function Disorder, Postoperative Delirium, Adverse Event, Death
- Trial name
- NCT05462938
- Testing
- Continuous infusion of propofol, Continuous infusion of dexmedetomidine
- Where
- Greece
- Volunteers
- 65 people
- Sponsor
- University of Ioannina
Renal Cell Carcinoma (RCC), Renal Function Abnormal
Ischemic Preconditioning Reduces the Severity of Acute Kidney Injury After Partial Nephrectomy
It is demonstrated that remote ischemic preconditioning can alleviate the degree of acute renal injury on the operated side in patients undergoing partial nephrectomy.
- Trial name
- NCT07497958
- Testing
- Ischemic preconditioning, NO ischemic preconditioning
- Where
- China
- Volunteers
- 174 people
- Sponsor
- Sun Yat-sen University
Chronic Allograft Nephropathy
Calcineurin Inhibitor Minimisation in Renal Transplant Recipients With Stable Allograft Function
The purpose of this trial is to ascertain whether the withdrawal of calcineurin inhibitors (CNI) will lead to less kidney transplant damage when compared with minimisation.
- Trial name
- CNIM-SRT (NCT00541814)
- Testing
- Cyclosporine
- Where
- United Kingdom
- Volunteers
- 90 people
- Sponsor
- University Hospital Birmingham
Kidney Failure, Acute
Mean Arterial Pressure (MAP) and Renal Perfusion: Evaluation of Critically Ill Patients With Normal Creatinine or Reduced Renal Function
The purpose of this study is to evaluate the renal perfusion depending on the MAP.
- Trial name
- NCT00117416
- Testing
- controlling the MAP
- Where
- Belgium
- Sponsor
- University Hospital, Ghent
End Stage Renal Disease, Hemodialysis Complication
Prevalence of Postural Abnormalities in Dialysis Patients
The goal of this observational study is to investigate and compare the prevalence of forward head , hyper kyphosis and balance in hemodialysis and peritoneal dialysis patients.
- Conditions
- End Stage Renal Disease, Hemodialysis Complication, Peritoneal Dialysis Complication
- Trial name
- NCT06350552
- Where
- Iran
- Volunteers
- 395 people
- Sponsor
- Pardis Specialized Wellness Institute
Endometriosis, Endometriosis (Diagnosis)
Deep Endometriosis Affecting the Urogenital Tract: Long-term Outcomes and Impact on Renal Function
Endometriosis is a chronic estrogen-dependent disease characterized by the presence and growth of endometrium-like tissue outside the uterine cavity.
- Conditions
- Endometriosis, Endometriosis (Diagnosis), Urinary Tract Diseases
- Trial name
- RENDO (NCT07776574)
- Where
- Czechia
- Volunteers
- 20 people
- Sponsor
- Charles University, Czech Republic
Chronic Kidney Diseases, Chronic Heart Failure
The Impact of CRT on Renal Function
The study is observational, prospective, including patients undergoing CRT-D / CRT-P implantation in the department of cardiology.
- Trial name
- NCT04516525
- Testing
- cardiac resynchronisation therapy (CRT) implantation
- Volunteers
- 74 people
- Sponsor
- University of Rzeszow
Hypertension, Hyperhomocysteinemia
CSPPT- Chronic Kidney Diseases Study
The purpose of this trial is to confirm that enalapril maleate and folic acid tablets is more effective in preventing renal function decline among the patients with primary hypertension when compared to enalapril maleate.
- Trial name
- CSPPT-CKD (NCT01871740)
- Testing
- Enalapril maleate and folic acid tablets, Enalapril maleate
- Where
- 2 sites in China
- Sponsor
- Shenzhen Ausa Pharmed Co.,Ltd
Kidney Disease, Chronic, Transplant Complication
Plant-based Diet for Kidney Transplant Recipients
The goal of this clinical trial is to evaluate cardiometabolic and inflammatory parameters in kidney transplant recipients after transitioning to a plant-based diet (PBD).
- Conditions
- Kidney Disease, Chronic, Transplant Complication, Hypertension, Diabetes Mellitus
- Trial name
- NCT06186843
- Testing
- Plant-based diet
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- George Washington University
Type 2 Diabetic Nephropathy With Elevated Blood Lead Burden
A Prospective Trial Of Oral Lead Chelation To Slow Renal Function Decline In Lead-Loaded Type 2 Diabetic Nephropathy Patients
This is a single-arm prospective clinical study conducted at The Fourth Affiliated Hospital of Zhejiang University School of Medicine.
- Trial name
- NCT07709871
- Testing
- Dimercaptosuccinic acid oral chelation therapy
- Volunteers
- 42 people
- Sponsor
- The Fourth Affiliated Hospital of Zhejiang University School of Medicine
Type II Diabetic Patients With Nephropathy
Microbial Soy Milk Consumption, Inflammation and Renal Function Among Type 2 Diabetic Patients With Nephropathy
The aim of the present study was to determine the effects of fortified soy milk with L. planetarium A7 on a cytokine receptor, an adipokine and renal function biomarkers in type II diabetic patients with nephropathy.
- Trial name
- NCT02704884
- Testing
- probiotic soy milk
- Where
- Iran
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Isfahan University of Medical Sciences
Congestive Heart Failure
Study to Evaluate the Effect of SLV320 in Addition to Chronic Furosemide Treatment on Renal Function in Subjects With Congestive Heart Failure and Impaired Renal Function
This is a randomized, double-blind, placebo-controlled, multi-center, sequential cohort study in subjects with congestive heart failure (CHF) and impaired renal function who are on stable furosemide treatment (³ 40 mg daily).
- Trial name
- NCT00568009
- Testing
- SLV320
- Where
- 72 sites in United States, Argentina and 8 more
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Solvay Pharmaceuticals
Healthy
PK Study of Intranasal RX0041-002 in Subjects With Severe Renal Impairment and Normal Renal Function
The primary objective of this study is to evaluate the potential effect of renal impairment on the systemic pharmacokinetics of acute Intranasal RX0041-002.
- Trial name
- NCT02775955
- Testing
- RX0041
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Pharmaceutical Project Solutions, Inc.
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