Clinical trials: Kidney Functional
Acute Renal Failure (ARF)
Venous Congestion and Acute Renal Failure in Cardiac Surgery Postoperative
Acute renal failure (ARF) is a frequent complication in the postoperative cardiac surgery, and is a major risk factor for mortality in this context.
- Trial name
- COVD (NCT03013621)
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Strasbourg, France
Chronic Kidney Disease stage3 and 4, Type 2 Diabetes Mellitus
Pentoxifylline Effect in Patients With Diabetic Nephropathy.(PENFOSIDINE STUDY)
One of the purposes of the management of the patient with chronic kidney disease (CKD)is to slow the decline of renal function. The mechanisms by which the renal function declines involve inflammatory and fibrotic responses due…
- Trial name
- PENFOSIDINE (NCT03664414)
- Testing
- pentoxifylline
- Where
- Mexico
- Volunteers
- 196 people
- Sponsor
- Maria Eugenia Galván Plata
Chronic Kidney Disease (Stages 4 and 5), Chronic Kidney Disease 5D
The Practicality and Utility of Measured vs Estimated GFR in adCKD
The goal of this observational study is to assess if new ways of measuring kidney function can better predict when individuals will become symptomatic due to kidney failure, and whether residual kidney function can be accurately…
- Trial name
- NCT07450534
- Testing
- Iohexol Inj 300 MG/ML Diagnostic aid/agent used to measure glomerular filtration rate (GFR)
- Where
- United Kingdom
- Volunteers
- 150 people
- Sponsor
- Manchester University NHS Foundation Trust
Kidney Impairment
A Study of RAY1225 in Participants With Impaired Kidney Function
The purpose of this study is to assess how fast RAY1225 gets into the blood stream and how long it takes the body to remove it in participants with impaired kidney function compared to healthy participants.
- Trial name
- NCT06613763
- Testing
- RAY1225
- Where
- China
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Guangdong Raynovent Biotech Co., Ltd
Secondary Hypothyroidism
Thyroid Function in Critically Ill Patients With Acute Kidney Injury
The objective of this study was to assess the changes in thyroid hormones and its activity during CRRT in patients with Acute Kidney Injury.
- Trial name
- NCT04767763
- Testing
- Assessment of TSH, fT3, fT4,TRH, TT3, TT4, rT3 in patients with CVVHDF
- Where
- Poland
- Volunteers
- 32 people
- Sponsor
- Medical University of Gdansk
Kidney Transplantation, Ischemic Reperfusion Injury
The Effect of Remote Postconditioning on Graft Function in Patients Undergoing Living-related Kidney Transplantation
The purpose of this study is to investigate whether upper limb ischemic postconditioning can improve renal function and decrease ischemic-reperfusion injury in patients undergoing living donor kidney transplantation.
- Conditions
- Kidney Transplantation, Ischemic Reperfusion Injury, Remote Ischemic Postconditioning
- Trial name
- NCT01363687
- Testing
- remote ischemic postconditioning
- Where
- South Korea
- Volunteers
- 60 people
- Sponsor
- Samsung Medical Center
Dyslipidemia
Pharmacokinetics of Anacetrapib (MK0859) in Subjects With Impaired Renal Function (MK-0859-038)
This study will evaluate the Area Under the Curve (AUC(0 to infinity)) of anacetrapib in subjects with impaired renal function and healthy matched control subjects.
- Trial name
- NCT01122667
- Testing
- anacetrapib
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Merck Sharp & Dohme LLC
Core Temperature, Telomere Length, Mean Leukocyte
Mitigating Heat Stress Among Rickshaw Drivers in Bangladesh
The goal of the experimental study is to understand the impact of heat stress on core temperature and telomere length. Investigators will recruit rickshaw drivers who use manual power to push their rickshaws and randomly assign…
- Conditions
- Core Temperature, Telomere Length, Mean Leukocyte, Kidney Function Issue
- Trial name
- NCT06956430
- Testing
- Battery-powered rickshaw
- Volunteers
- 300 people
- Sponsor
- University of California, Berkeley
Liver Transplantation
Efficacy of Everolimus in Combination With Tacrolimus in Liver Transplant Recipients
This trial evaluated the efficacy and safety of Everolimus in combination with tacrolimus versus a standard immunosuppressive regimen concerning kidney function in liver transplant recipients.
- Trial name
- HEPHAISTOS (NCT01551212)
- Testing
- Everolimus, Tacrolimus, Corticosteroids
- Where
- 15 sites in Germany
- Volunteers
- 339 people
- Sponsor
- Novartis Pharmaceuticals
Prostate Cancer
Hydroxyethyl Starch and Renal Function After Radical Prostatectomy
The purpose of this project is to investigate if hydroxyethyl starch (HES) is potential nephrotoxic and examine the effects on the circulation and kidneys during administration of HES during surgery.
- Trial name
- VORA (NCT01486563)
- Testing
- Voluven (Hydroxyethyl starch 130/0,4), Sodium Chloride 9 mg/ml
- Where
- Denmark
- Volunteers
- 40 people
- Sponsor
- Regional Hospital Holstebro
End Stage Renal Disease
Goal Directed Fluid Administration for Kidney Transplantation
The goal of the proposed study is to evaluate the efficacy of a goal-directed fluid administration algorithm on early graft function in patients undergoing kidney transplantation.
- Trial name
- NCT02192086
- Testing
- goal directed fluid therapy, Control Group
- Volunteers
- 21 people
- Sponsor
- Medical University of South Carolina
Kidney Transplantation
Study Comparing Graft Function in Renal Allograft Recepients Receiving Reduced or Standard Dose CsA With Sirolimus
This study evaluated renal graft function (based on calcuated creatinine clearance) 12 months after transplantation in patients receiving either a regimen of reduced dose or standard dose cyclosporine in combination with…
- Trial name
- NCT00518375
- Testing
- Rapamune® (Sirolimus), Neoral® (Cyclosporine), Corticosteroids
- Volunteers
- 250 people
- Sponsor
- Wyeth is now a wholly owned subsidiary of Pfizer
IGA Glomerulonephritis
Pilot Study of Enalapril and Renal Function in Patients With IgA Nephropathy
OBJECTIVES: I. Determine the most sensitive outcome measures (functional or morphological) of a progressive renal injury in patients with IgA nephropathy. II.
- Trial name
- NCT00006137
- Testing
- enalapril
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- National Center for Research Resources (NCRR)
Participants Scheduled for Surgery Under Spinal Anesthesia Without Impairment of Renal, Hepatic, Cardiac or Respiratory Function
Autonomic Modulation After Spinal Anesthesia With Depth of Anesthesia and Vital Signs.
Spinal anaesthesia has the advantage that produced nerve block by the injection of local anaesthetic into cerebrospinal fluid (CSF).
- Trial name
- NCT04275375
- Testing
- observation study about the autonomic response after spinal anesthesia
- Where
- Taiwan
- Volunteers
- 46 people
- Sponsor
- National Central University
Proton Pump Inhibitor Allergy
Effect of Proton Pump Inhibitor of Daily Use for One Month on Kidney Function Test
The aim of this study to: evaluate the association between prolonged use of PPI and adverse renal outcomes on patients with normal renal function and others with abnormal renal function
- Trial name
- NCT04022837
- Testing
- Pantoprazole 40mg
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Assiut University
Pharmacokinetics and Pharmacodynamics
Vancomycin Dose Optimization in Obesity
The goal of this clinical trial is to learn how to optimize vancomycin dosing in obese adults based on weight and kidney function. It will also assess the safety of different vancomycin dosing strategies.
- Trial name
- NCT06601257
- Testing
- Vancomycin (IV)
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Chronic Kidney Diseases
Dapagliflozin on Renal Morphology and Renal Perfusion in Patients One Year After Kidney Transplantation
The aim of this study is to observe the mechanisms of dapagliflozin on the renal interstitial tissue and renal perfusion. For this purpose, renal transplanted patients as an excellent model of CKD and high cardiovascular risk…
- Trial name
- NCT06560801
- Testing
- Dapagliflozin 10mg Tab
- Where
- Germany
- Volunteers
- 48 people
- Sponsor
- University of Erlangen-Nürnberg Medical School
Kidney Failure, Chronic, Cardiovascular Diseases
Effects of Phosphate Binding With Sevelamer in Stage 3 Chronic Kidney Disease
The purpose of this study is to determine whether lowering phosphate in patients with early chronic kidney disease with the phosphate binder sevelamer has beneficial effects on cardiovascular structure and function.
- Trial name
- NCT00806481
- Testing
- Sevelamer carbonate
- Where
- United Kingdom
- Volunteers
- 120 people
- Sponsor
- University Hospital Birmingham NHS Foundation Trust
Myelofibrosis
To Evaluate the Pharmacokinetics and Safety of TQ05105 Tablet in Renal Impairment Subjects
This is an open, open-label, parallel, single-dose, phase I clinical study designed to evaluate the pharmacokinetic (PK) profile of TQ05105 tablet in patients with renal impairment after a single dose, and to evaluate the urinary…
- Trial name
- NCT06598956
- Testing
- TQ05105
- Where
- China
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
Type 2 Diabetes Mellitus
A Study to Assess the Pharmacokinetics, Pharmacodynamics of ASP1941 in Diabetes Mellitus Patients With Renal Impairment
The primary objective of this study is to compare the pharmacokinetics of ASP1941 in type 2 diabetes mellitus patients with normal renal function and those with mild or moderate renal impairment.
- Trial name
- NCT01097681
- Testing
- ASP1941
- Where
- 2 sites in Japan
- Volunteers
- 25 people
- Sponsor
- Astellas Pharma Inc
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.