Clinical trials: Kidney Insufficiency
Acute Kidney Injury, Chronic Kidney Diseases
Histopathological Analysis of Renal Biopsies With Dynamic Full-field Optical Coherence Tomography, a Comparison to Conventional Histopathological Findings for the Diagnosis of Either Acute Kidney Injury or Chronic Kidney Disease in Routine Practices (NEPHROCT)
Kidney biopsy play a key role for the investigation of either acute kidney injury or chronic kidney disease. Despite possible complications due to the invasive nature of the biopsy, such procedure is still essential in a number…
- Conditions
- Acute Kidney Injury, Chronic Kidney Diseases, Tomography, Optical Coherence
- Trial name
- NEPHROCT (NCT05728216)
- Testing
- Dynamic full-field optical coherence tomography analysis of kidney biopsy
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Centre Hospitalier William Morey - Chalon sur Saône
Diabetes, Hypercholesterolemia
Baromètre Santé Adulte 2021-2022
In 2021-2022, Agence Sanitaire et Sociale Nouvelle Calédonie (ASSNC) is undertaking the "Baromètre Santé Adulte" for the third time.
- Conditions
- Diabetes, Hypercholesterolemia, Renal Failure, Dengue Fever
- Trial name
- NCT05218304
- Testing
- Blood sample
- Where
- New Caledonia
- Volunteers
- 5,471 people, healthy volunteers welcome
- Sponsor
- Agence Sanitaire et Sociale de Nouvelle Calédonie
Kidney Disease, Chronic, Diabetic Kidney Disease (DKD)
Mesenchymal Stem Cells for Chronic Kidney Diseases
This study will evaluate the effect of intravenous injection of umbilical cord tissue derived mesenchymal stem cells (UMSCs) on the improvement of renal function in patients with chronic kidney disease (CKD) at stage 3 or 4, with…
- Conditions
- Kidney Disease, Chronic, Diabetic Kidney Disease (DKD), Hypertensive Nephropathy
- Trial name
- NCT07240987
- Testing
- 0.9% sodium chloride, MSCs
- Volunteers
- 32 people
- Sponsor
- The First Affiliated Hospital of Air Force Medical University
End-stage Renal Disease
Ellipsys Vascular Access System Registry
Ellipsys Vascular Access System Registry will enroll up to 100 patients to evaluate the use and performance of the Ellipsys Vascular Access System when it is used within its intended use in accordance with standard of care in a…
- Trial name
- NCT03454113
- Testing
- Ellipsys Vascular Access
- Where
- 5 sites in Germany
- Volunteers
- 17 people
- Sponsor
- Medtronic Endovascular
Kidney Diseases
Renasight Clinical Application, Review and Evaluation (RenaCARE) Study
This study is an open-label, multi-center study evaluating the clinical utility of Renasight in the diagnosis and management of kidney disease.
- Trial name
- RenaCARE (NCT05846113)
- Testing
- Renasight
- Where
- 31 sites in United States
- Volunteers
- 1,720 people
- Sponsor
- Natera, Inc.
Sepsis, Surgery
Inflammatory Mediators of Acute Kidney Injury in Intensive Care
Acute kidney injury (AKI) affects more than 50% of patients admitted to the intensive care unit. The most common underlying cause is sepsis. Severe AKI in combination with sepsis is associated with high mortality.
- Conditions
- Sepsis, Surgery, Acute Kidney Injury
- Trial name
- PronMed (NCT03720860)
- Where
- Sweden
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Uppsala University
Chronic Kidney Disease, Pain, Procedural
Comparing Mirror and Music for Dialysis Needle Pain
Inserting needles into the vascular access (fistula) is a major source of pain and anxiety for many hemodialysis patients. This study compared two simple, non-drug techniques to reduce this pain: listening to music and looking…
- Conditions
- Chronic Kidney Disease, Pain, Procedural, Arteriovenous Fistula
- Trial name
- MIRROR-MUSIC (NCT07320859)
- Testing
- Mirror Therapy (Visual Illusion Therapy), Music Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people
- Sponsor
- Izmir Kavram Vocational School
Acute Kidney Injury, Critical Illness
Renal Resistive Index as a Predictor of Acute Renal Impairment in High-risk Patients
To study the ability of RRI, measured by bedside Doppler ultrasound, in detecting acute kidney injury in high-risk patients admitted to surgical intensive care unit, Aswan university hospital, compared with renal biomarkers and…
- Trial name
- NCT06386796
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Aswan University
Renal Transplantation, Chronic Kidney Insufficiency
Urinary Biomarkers in Paediatric Kidney Transplantation (pKTx)
This study aims to test and validate the panel of study urinary biomarker to assess whether (1) reference values differ between paediatric renal transplant patients, patients with chronic kidney disease stage IV and V (CKD IV-V)…
- Conditions
- Renal Transplantation, Chronic Kidney Insufficiency, Healthy Controls
- Trial name
- NCT05208788
- Testing
- Biomarker test
- Where
- Germany
- Volunteers
- 186 people, healthy volunteers welcome
- Sponsor
- University Hospital Tuebingen
Acute Kidney Failure
Neutrophile Gelatinase Associated Lipocalin Evaluation in Septic Acute Kidney Injury
Acute kidney injury (AKI) is a major organ failure in septic shock. Current medical tests (serum creatinine and urea) cannot identify AKI until approximately 48 hours after it occurs.
- Trial name
- NESAKI (NCT01122225)
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Université Victor Segalen Bordeaux 2
Liver Failure
A Randomized Controlled Clinical Trial of Thymoglobulin® After Liver Transplantation
This is a 24-month, Phase II, multi-center, two-arm, randomized controlled study of adult patients receiving a single organ liver transplant from a deceased donor; the purpose being to determine the efficacy of Thymoglobulin®…
- Trial name
- NCT02544113
- Testing
- Thymoglobulin
- Where
- 4 sites in United States
- Volunteers
- 110 people
- Sponsor
- The Cleveland Clinic
Healthy Participants
A Study to Investigate the Safety, Tolerability and Pharmacodynamics of AZD4144 in Participants With Obesity
The aim of this study is to evaluate the safety and tolerability, and pharmacodynamics (PD) of AZD4144 administered as repeated daily oral dosing.
- Trial name
- NCT06942923
- Testing
- AZD4144
- Where
- Germany
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Complicated Skin and Skin Structure Infections, S. Aureus Bacteremia
Study of Daptomycin Safety and Efficacy for Complicated Skin and Skin Structure Infections (cSSSI) and Bacteremia in Renal Impairment
This is a multicenter, randomized, evaluator-blinded, comparator-controlled study. Participants were to be randomized (1:1) to daptomycin or comparator, stratified by degree of renal impairment (creatinine clearance [CLcr] 30 …
- Conditions
- Complicated Skin and Skin Structure Infections, S. Aureus Bacteremia, Renal Impairment
- Trial name
- RENSE (NCT01104662)
- Testing
- Vancomycin, Daptomycin, Semi-Synthetic Penicillin
- Where
- 10 sites in United States
- Volunteers
- 92 people
- Sponsor
- Cubist Pharmaceuticals LLC, a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)
Kidney Failure, Chronic
Case-Control Study on Analgesics and Nephropathy (SAN)
The objective of the international, multicenter case-control study was to evaluate the association between end-stage renal disease (ESRD) and use of non-phenacetin-containing analgesics with particular emphasis on combined…
- Trial name
- NCT00302835
- Testing
- non-phenacetin containing analgesics
- Where
- Germany
- Volunteers
- 4,200 people
- Sponsor
- Center for Epidemiology and Health Research, Germany
Anemia, Dialysis-Dependent Chronic Kidney Disease
Efficacy and Safety Study to Evaluate Vadadustat for the Correction or Maintenance Treatment of Anemia in Participants With Incident Dialysis-dependent Chronic Kidney Disease (DD-CKD)
A multicenter, randomized, open-label, active-controlled Phase 3 study for the correction or maintenance treatment of anemia in participants with incident dialysis-dependent chronic kidney disease (DD-CKD).
- Trial name
- NCT02865850
- Testing
- Vadadustat, Darbepoetin alfa
- Where
- 118 sites in United States, Argentina and 9 more
- Volunteers
- 369 people
- Sponsor
- Akebia Therapeutics
Chronic Kidney Failure
Reduction of Heparin Dose in Dialysis With Evodial System
The current clinical study aims at defining an index of Anti Xa, which is the marker to evaluate the activity of heparin, at the end of the dialysis treatment and so showing the possibility to decrease heparin doses during…
- Trial name
- RHODES (NCT00781690)
- Testing
- Evodial hemodialysers and Evodia blood lines
- Where
- 7 sites in France, Germany and 2 more
- Volunteers
- 53 people
- Sponsor
- Vantive Health LLC
Degenerative Heart Valve Disease, Heart Valve Calcification
Calcium-Phosphorus Regulation Therapy on Heart Valve Disease
The goal of this clinical trial is to learn if calcium-phosphorus regulation therapy can slow the progression of heart valve calcification in patients with degenerative heart valve disease and chronic kidney disease (CKD).
- Conditions
- Degenerative Heart Valve Disease, Heart Valve Calcification, Chronic Kidney Disease(CKD), Calcium-Phosphorus Metabolism Disorders
- Trial name
- NCT06660524
- Testing
- Sevelamer, Calcium carbonate
- Where
- China
- Volunteers
- 196 people
- Sponsor
- China National Center for Cardiovascular Diseases
End Stage Renal Disease (ESRD), Diabetes
Dianeal, Extraneal, Nutrineal (D-E-N) Versus Dianeal Only in Diabetic Continuous Ambulatory Peritoneal Dialysis (CAPD) Patients
Primary Objective: To demonstrate that use of glucose sparing prescriptions, Dianeal, Extraneal, Nutrineal (D-E-N) versus Dianeal only, in diabetic (Type 1 and Type 2) Continuous Ambulatory Peritoneal Dialysis (CAPD) patients…
- Conditions
- End Stage Renal Disease (ESRD), Diabetes, CAPD
- Trial name
- EDEN (NCT01219959)
- Testing
- Dianeal, Dianeal, Extraneal, Nutrineal
- Where
- 16 sites in Colombia
- Volunteers
- 71 people
- Sponsor
- Vantive Health LLC
Renal Failure
Quanta Home Run Trial
The purpose of this study is to determine non-inferiority in safety and efficacy when Quanta SC+ is used in the self-care home environment compared to a hemodialysis facility.
- Trial name
- NCT04975880
- Testing
- SC+ Hemodialysis System
- Where
- 13 sites in United States
- Volunteers
- 46 people
- Sponsor
- Quanta Dialysis Technologies Ltd
HIV Infections, Kidney Disease
A Study of Zidovudine in HIV-Infected Patients With Kidney Problems
To determine how zidovudine (AZT) for the treatment of HIV infection is metabolized and excreted or eliminated in patients with infected or diseased kidneys.
- Trial name
- NCT00000685
- Testing
- Zidovudine
- Where
- 2 sites in United States
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.