Clinical trials: Kidney Insufficiency
Acute Kidney Injury, End-stage Renal Disease
Hemodynamic Effects of Blood Flow Variation in Continuous Renal Replacement Therapy
Purpose of this study is to evaluate the short-term hemodynamic effects of changes in blood flow rates in critically ill patients receiving continuous renal replacement therapy.
- Trial name
- NCT03078504
- Testing
- continuous renal replacement therapy using System One (TM) setup (Nxstage)
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- St. Louis University
Acute Kidney Injury
Specimen Stability Study
To collect and process urine samples from critically ill subjects for use in assessing the effects of various urine sample freezing and storage conditions on biomarker test results.
- Trial name
- NCT01846884
- Where
- 6 sites in United States
- Volunteers
- 124 people
- Sponsor
- Astute Medical, Inc.
Acute Kidney Injury, Transfusion-Associated Circulatory Overload
Effects of Red Blood Cells Transfusion on Renal Blood Flow
The renal Doppler resistive index (RRI) is a noninvasive tool that has been used to assess renal perfusion in the intensive care unit (ICU) setting. It is associated with the occurrence of acute kidney injury (AKI).
- Conditions
- Acute Kidney Injury, Transfusion-Associated Circulatory Overload, Anemia, Fluid Overload
- Trial name
- NCT04194047
- Testing
- Transfusion, Crystalloids infusion
- Where
- Italy
- Volunteers
- 33 people
- Sponsor
- Università degli Studi di Ferrara
Chronic Kidney Diseases
Propolis Effects in Patients With Chronic Kidney Disease
The aim of this study is to determine the impact of Propolis on proteinuria reduction and protection of the glomerular filtration rate in chronic renal failure patients.
- Trial name
- NCT02766036
- Testing
- Propolis
- Where
- Brazil
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo General Hospital
Chronic Kidney Diseases
Study of the Prevalence of Iron Deficiency in Patients With Chronic Renal Failure But Non-Dialysis (CARENFER IRC-ND)
Despite its known prevalence, a recent study conducted with Prof. Cacoub (unpublished) on the national health insurance database showed that iron deficiency was a poorly diagnosed and poorly treated comorbidity.
- Trial name
- NCT04123145
- Testing
- Iron status testing
- Volunteers
- 1,100 people
- Sponsor
- VIFORFRANCE
Acute Renal Failure, Hemorrhage
Impact of Renal Replacement Therapy on Coagulation Profile of Patients with Acute Renal Failure
Renal failure and high plasmatic level of urea have been associated with an increased risk of hemorrhage in surgical patients. There is only sparse data on the impact of renal replacement therapy on homeostatic parameters.
- Conditions
- Acute Renal Failure, Hemorrhage, Coagulation Disorder
- Trial name
- HEMOSTIR (NCT03536195)
- Where
- France
- Volunteers
- 14 people
- Sponsor
- University Hospital, Brest
Renal Impairment
A Study to Evaluate the Pharmacokinetics and Safety of DBPR108 in Subjects With Renal Impairment
This is an open-label, single-dose study to evaluate the pharmacokinetics and safety of DBPR108 in subjects with mild, moderate, severe renal impairment and subjects with kidney failure compared to the matched control subjects…
- Trial name
- NCT04859439
- Testing
- DBPR108 tablets
- Where
- China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- CSPC ZhongQi Pharmaceutical Technology Co., Ltd.
End Stage Renal Disease (ESRD)
Food Preparation Effects on Gut Bacteria in Patients on Peritoneal Dialysis
This is an intervention study of the effects of food preparation on the gut bacteria in patients with end stage renal disease on peritoneal dialysis.
- Trial name
- NCT02467530
- Testing
- AGE
- Where
- United States
- Volunteers
- 103 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Acute Heart Failure, Acute Renal Failure
Bladder Pressure Predicting Renal Failure in Critically Ill Patients as Compared to Hemodynamic Parameters
Studies have shown that more than 30% of the overall acute decompensated heart failure (ADHF) patients develop renal dysfunction.
- Trial name
- NCT01363505
- Testing
- BARD® Intra-abdominal Pressure monitor
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Northwell Health
Acute Kidney Injury
The Effect of Nafamostat Mesilate in Prolonging Filter Patency With Patients on Continuous Renal Replacement Therapy
Continuous renal replacement therapy (CRRT) has been considered as an effective modality for renal replacement therapy in hemodynamically unstable patients within intensive care unit (ICU) except for the necessity of…
- Trial name
- NCT01761994
- Testing
- Anticoagulation with nafamostat mesilate
- Where
- South Korea
- Volunteers
- 66 people
- Sponsor
- Yonsei University
Chronic Kidney Disease Stage 5, Peritoneal Dialysis Complication
Utility of Telemedicine in the Follow-Up of Patients in Peritoneal Dialysis
Peritoneal dialysis (PD) technology is available but has not been tested in the real world. Therefore, the aim of this study is to test the utility of telemedicine in reducing mortality, hospitalizations, unscheduled visits, and…
- Trial name
- NCT04034966
- Testing
- Claria telemedicine device
- Where
- Mexico
- Volunteers
- 750 people
- Sponsor
- Coordinación de Investigación en Salud, Mexico
Stem Cell Transplant Complications, Acute Graft Versus Host Disease
Study on the Serum Metabolic Markers and Early Complications After Allo-HSCT： Cohort Study
This study aims to establish a cohort of 500 patients with hematological disease who undergoing allogeneic hematopoietic stem cell transplantation in the northwest region.
- Conditions
- Stem Cell Transplant Complications, Acute Graft Versus Host Disease, Acute Kidney Injury, Major Adverse Cardiac Events
- Trial name
- NCT06386445
- Testing
- Serum metabolomics sequencing
- Volunteers
- 500 people
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University
Acute Kidney Injury
Diagnostic Value of Urinary Indices in Differentiating Pre-renal and Renal Acute Kidney Injury
The study aims to evaluate the diagnostic value of urinary indices in differentiating pre-renal and renal acute kidney injury among critically ill patients.
- Trial name
- NCT02376712
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Peking Union Medical College Hospital
Coronary Artery Disease, Renal Impairment
Renal Effects of Two Iodinated Contrast Media in Patients at Risk Undergoing Coronary Angiography
The main purpose of this study is to evaluate and compare the effects on kidney function of two contrast media, the iso-osmolar iodixanol and the low-osmolar iopamidol in patients at risk of kidney damage associated with the…
- Trial name
- NCT00209430
- Testing
- Iodixanol 320 mgI/mL
- Where
- Sweden
- Volunteers
- 408 people
- Sponsor
- GE Healthcare
Renal Failure, Dialysis
(TIMP-2)x(IGFPB7) to Predict Acute Kidney Injury (AKI) in Aortic Surgery
New biomarkers that predict the development of renal dysfunction in patients with aortic surgery are urgently needed. The investigators investigate whether urinary (TIMP-2)x(IGFBP7) predicts postoperative Acute Kidney Injury…
- Conditions
- Renal Failure, Dialysis, Aortic Surgery, Biomarker
- Trial name
- TIGER (NCT03469765)
- Testing
- does not apply
- Where
- Switzerland
- Volunteers
- 100 people
- Sponsor
- Jörg Schefold
Vaccination; Infection
Study of the Impact of Time of Vaccination on Response to Influenza Vaccine in Patients With Chronic Renal Failure
Immune response to influenza vaccine in patients with chronic renal insufficiency.
- Trial name
- CHRONOVAX2 (NCT06907667)
- Testing
- Vaccine injection
- Where
- France
- Volunteers
- 735 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Chronic Kidney Diseases, Periapical Lesions
Association of Apical Periodontitis With Chronic Kidney Disease
This investigation is aimed to assess the prevalence and severity of apical periodontitis (AP) in different stages of CKD patients and its impact on the systemic (nutritional and inflammatory) markers was compared to healthy…
- Trial name
- NCT05818657
- Testing
- levels of CKD markers, Oral health status, apical periodontitis, systemic inflammatory marker, Oral health status, apical periodontitis
- Where
- India
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Hypertension, Diabetes Mellitus
Effectiveness of Laser Acupuncture in Improving Arterial Stiffness Among Patients With Cardiorenal Metabolic Syndrome
Background: Cardio-renal metabolic syndrome (CRMS) is a vicious cycle of cardiac, renal, and metabolic disease, representing a high-risk for atherosclerosis.
- Conditions
- Hypertension, Diabetes Mellitus, Chronic Kidney Disease, Cardio-Renal-Metabolic Syndrome
- Trial name
- NCT07543211
- Testing
- laser acupuncture
- Volunteers
- 35 people
- Sponsor
- National Yang Ming Chiao Tung University
Bleeding Disorder, Ischemic Stroke
XIENCE 28 USA Study
The XIENCE 28 USA Study is prospective, single arm, multi-center, open label, non-randomized trial to evaluate safety of 1-month (as short as 28 days) dual antiplatelet therapy (DAPT) in subjects at high risk of bleeding (HBR)…
- Conditions
- Bleeding Disorder, Ischemic Stroke, Hemorrhagic Stroke, Hematological Diseases
- Trial name
- NCT03815175
- Testing
- XIENCE, DAPT (aspirin and/or P2Y12 receptor inhibitor)
- Where
- 111 sites in United States, Austria and 13 more
- Volunteers
- 1,605 people
- Sponsor
- Abbott Medical Devices
Polycystic Kidney, Autosomal Dominant, Chronic Kidney Diseases
The Kidneys Ability to Concentrate and Dilute Urine in Patients With Autosomal Dominant Polycystic Kidney Disease
The ability to concentrate and dilute urine is primarily regulated via vasopressin (AVP) dependent Aquaporin-2 water channels (AQP2 channels) in the kidney's collecting duct.
- Trial name
- POVA (NCT04363554)
- Testing
- Fluid intake, Thirsting
- Where
- Denmark
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Regional Hospital Holstebro
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