Clinical trials: Kidney Stone Prevention
Kidney Stones
Struvite Stones Antibiotic Study
The aim of this research is to determine an effective antibiotic regimen following definitive surgical therapy of kidney stones caused by bacterial infection (struvite stones).
- Trial name
- NCT02375295
- Testing
- ciprofloxacin, cotrimoxazole-trimethoprim, macrodantin
- Where
- 12 sites in United States, Canada
- Volunteers
- 28 people
- Sponsor
- University of British Columbia
Urinary Calculi, Postoperative Care
WeChat-Based Digital Therapy to Improve Fluid Intake in Kidney Stone Patients: Study Protocol
The goal of this clinical trial is to learn Whether the WeChat-based applet works to prevent urinary calculi for postoperative patients.
- Conditions
- Urinary Calculi, Postoperative Care, Chronic Disease Prevention
- Trial name
- NCT06990672
- Testing
- Standard care, Experimental
- Where
- China
- Volunteers
- 148 people
- Sponsor
- The University of Hong Kong
Kidney Stone, Infection
Novel Antimicrobial Solution to Prevent Infections
Ureteroscopy is the most common surgical treatment for kidney stones. Although rare, sepsis after ureteroscopy can be a life-threatening complication, occuring in <3% of patients.
- Conditions
- Kidney Stone, Infection, Infection Associated With Catheter, Sepsis
- Trial name
- NCT07881822
- Testing
- antimicrobial irrigation
- Volunteers
- 50 people
- Sponsor
- Ohio State University
Kidney Stones
CaOx Stone Prevention
This single-center randomized controlled trial at Mount Sinai West will enroll 80 patients undergoing percutaneous nephrolithotomy for calcium oxalate stones.
- Trial name
- NCT07225764
- Testing
- Chlorthalidone, Low oxalate diet
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Kidney Stone, Nephrolithiasis
Trial to Assess the Efficacy of EMPAgliflozin and Personalized Dietary Counseling for Kidney STONE Prevention
The aim of this randomized trial with a 2-by-2 factorial design is to test the efficacy of the SGLT2 inhibitor empagliflozin and personalized dietary counseling based on 24-hr urine collection results and dietary assessments for…
- Conditions
- Kidney Stone, Nephrolithiasis, Dietary Exposure
- Trial name
- EMPASTONE (NCT06653738)
- Testing
- Empagliflozin 10 MG, Personalized dietary counseling, Generic dietary counseling
- Where
- 21 sites in France, Germany and 2 more
- Volunteers
- 400 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Paraffinoma, Granuloma, Foreign-Body
The GranStone Trial
This study will investigate whether treatment with empagliflozin or losartan can reduce the risk of kidney stone formation in patients with paraffin disease, a condition caused by the injection of paraffin oil into muscle tissue…
- Trial name
- NCT07828002
- Testing
- empagliflozin (Jardiance) 25 mg, Losartan 100 mg
- Where
- Denmark
- Volunteers
- 100 people
- Sponsor
- Martin Blomberg Jensen
Urolithiasis
Lime Powder Regimen (LPR) for Prevention of Renal Stone Recurrence
Lime powder regimen (LPR) is a lime-derived composition enriches with citrate/citric acid and potassium. LPR was invented to treat the renal stone patients with high risk of stone recurrence after stone removal.
- Trial name
- NCT03258190
- Testing
- Lime Powder Regimen
- Where
- Thailand
- Volunteers
- 137 people
- Sponsor
- Chulalongkorn University
Calculi, Renal, PCNL
Preoperative Prophylactic Fosfomycin Trometamol Versus 5-day Levofloxacin in Prevention of Postpercutaneous Nephrolithotomy Infectious Complications and Sepsis.
A randomized controlled trial comparing the use of preoperative prophylactic single dose fosfomycin trometamol versus levofloxacin in prevention of post-PCNL infectious complications and sepsis.
- Conditions
- Calculi, Renal, PCNL, Infectious Complications
- Trial name
- NCT07355907
- Testing
- PCNL
- Where
- Egypt
- Volunteers
- 210 people
- Sponsor
- Tanta University
Urolithiasis
sipIT2: Improving Adherence to Fluid Intake Guidelines for Kidney Stone Prevention
The purpose of this study is to examine the feasibility of using sipIT tools (i.e., wrist-worn sensors, smart water bottles, mobile applications) to increase compliance with physician-recommended fluid consumption guidelines in…
- Trial name
- NCT05196113
- Testing
- sipIT
- Where
- 2 sites in United States
- Volunteers
- 216 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Calcium Oxalate Urolithiasis
Mineral Water for Prevention of Renal Stones
The investigators would like to assess if the intake of high bicarbonate mineral water would not only increase total fluid intake but will also be able to give patients the additional benefit of correcting the urinary…
- Trial name
- NCT04638166
- Testing
- Mineral water, Plain water
- Where
- Singapore
- Volunteers
- 58 people
- Sponsor
- Singapore General Hospital