Clinical trials: Kidney Stones
Renal Calculi, Nephrolithiasis
Comparison Between Different Types of Flexible Ureteroscopes
The current study aims to compare the performance of three distinct single-use digital flexible ureteroscope types in terms of cost-effectiveness, postoperative complications, operating time, and stone-free rates (SFRs).
- Trial name
- FURS (NCT07360353)
- Testing
- LithoVue™ (Boston Scientific Corporation), WiScope® (OTU Medical Inc. (Silicon Valley, USA)), Single-Use Ureterorenoscope (Scivita Medical Technology Co., Ltd.)
- Where
- Egypt
- Volunteers
- 180 people
- Sponsor
- Ain Shams University
Kidney Stone
Research on Early Warning and Diagnosis & Treatment Pathway for Micro Kidney Stones
Exploring abnormal metabolism in kidney stone patients and developing drugs for kidney stone treatment and their mechanisms of action.
- Trial name
- NCT07350369
- Testing
- Detect the levels of metabolites in blood and urine
- Where
- China
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Xijing Hospital
Nephrolithiasis
Subcostal TAP Block For Percutaneous Nephrolithotomy
Percutaneous nephrolithotomy (PCNL) is a minimally- invasive procedure for removing kidney stones. The small incision of PCNL is performed medially from the posterior axillary line according to stones location.
- Trial name
- NCT03454139
- Testing
- Subcostal transversus abdominis plane block
- Volunteers
- 80 people
- Sponsor
- Istanbul University
Nephrolithiasis
Effect of Antihistamines on Ureteral Stent-Related Symptoms
This is a prospective, double-blind, randomized, open-label, single-center trial of up to 78 participants who are adult patients (aged 18-80 years) and are undergoing unilateral retrograde ureteroscopy with planned ureteral stent…
- Trial name
- NCT04726345
- Testing
- Fexofenadine Hcl 180Mg Tab
- Where
- United States
- Volunteers
- 78 people
- Sponsor
- Columbia University
Nephrolithiasis, Glomerulonephritis, Amyloidosis,AKI, CKD, Tubuli Interstitial, Urinary System Disorders in IBD Patients
Affection of Renal and Urinary System in IBD Patients
Detection and classification of different renal and urinary affection in patients with IBD that attended to Assist University Hospitals
- Trial name
- NCT06249243
- Volunteers
- 100 people
- Sponsor
- Assiut University
Urothelial Carcinoma, Renal Cell Carcinoma
Prospective Trial for Examining Hematuria Using Computed Tomography
The primary objective is to evaluate whether one-phase nephrographic CT (experimental) is sufficient to detect urothelial cell carcinoma in patients with hematuria compared to the traditional four-phase CT (control).
- Conditions
- Urothelial Carcinoma, Renal Cell Carcinoma, Renal Cyst, Renal Stone
- Trial name
- PROTEHCT (NCT04077359)
- Testing
- CT
- Where
- Norway
- Volunteers
- 300 people
- Sponsor
- Oslo University Hospital
Nephrolithiasis, Staghorn Calculus
Impact of Tranexamic Acid Use in Percutaneous Nephrolithotomy
This study is a double blinded randomized controlled trial evaluating the impact of tranexamic acid use on the transfusion rate in patients with complex kidney stones undergoing percutaneous nephrolithotomy.
- Trial name
- NCT02966236
- Testing
- Tranexamic Acid
- Where
- Brazil
- Volunteers
- 192 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Kidney Stone
Indapamide and Chlorthalidone to Reduce Urine Supersaturation for Kidney Stone Prevention
The aim of this study is to test the efficacy of the two long-acting thiazide-like diuretics indapamide and chlorthalidone in reducing urine supersaturation for calcium oxalate and calcium phosphate compared to the short-acting…
- Trial name
- INDAPACHLOR (NCT06111885)
- Testing
- Indapamide 2.5 MG, Hydrochlorothiazide 50Mg, Chlorthalidone 25mg
- Where
- Switzerland
- Volunteers
- 99 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Kidney Stones
Clinical Evaluation of BackStop in Patients Undergoing Ureteroscopic Lithotripsy
The purpose of this clinical study is to evaluate BackStop, a polymer-based device that is intended to be used during ureteroscopic lithotripsy to prevent retrograde stone migration.
- Trial name
- NCT02122341
- Testing
- BackStop
- Where
- 2 sites in United States
- Volunteers
- 35 people
- Sponsor
- University of Southern California
Stone Ureter, Stone, Kidney
Silodosin in Facilitating Flexible Uretroscopy
This study aims to provide robust evidence on whether a specific, potent pre-operative medication (silodosin) can make the critical step of ureteral access (UAS placement after dilation) easier and safer during f-URS for kidney…
- Trial name
- NCT07068087
- Testing
- Preoperative sioldosin to facilitate ureteric access sheath insertion in RIRS
- Where
- Egypt
- Volunteers
- 42 people
- Sponsor
- Ain Shams University
Primary Hyperoxaluria Type 1, PH1
Phase I Exploratory Study of YOLT-203 in Patients With Primary Hyperoxaluria Type 1 (PH1)
This is a single-arm, open-label, single-dose dose-escalation study. It aims to evaluate the safety and tolerability of YOLT-203 in Chinese patients with Primary Hyperoxaluria Type 1 (PH1), and to preliminarily assess the effect…
- Trial name
- NCT07776626
- Testing
- YOLT-203
- Where
- China
- Volunteers
- 9 people
- Sponsor
- YolTech Therapeutics Co., Ltd
Unilateral Ureteral Stone, Renal Stone Fragments ≤ 2mm
Feasibility Study of the Uriprene Stent Following Uncomplicated Ureteroscopy
A prospective, single-center, single-arm, trial to demonstrate safety and device performance of the ADVA-Tec Uriprene™ Degradable Temporary Ureteral Stent. This is a first-in-man clinical study in a small human population.
- Trial name
- URIPRENE (NCT02032316)
- Testing
- Post-Ureteroscopy ADVA-Tec Uriprene™ Degradable Temporary Ureteral Stent
- Where
- Canada
- Volunteers
- 8 people
- Sponsor
- Adva-Tec
Renal Stones
Flexible Ureteroscopy Versus ESWL in the Management of Lower Calyceal Stones
to assess safety, efficacy of Flexible ureteroscopy (FURS) holmium:YAG laser lithotripsy (LL) compared to extracorporeal shockwave lithotripsy (ESWL) in management of lower calyceal stones (LC) stones.
- Trial name
- NCT02658942
- Testing
- Ureteroscopy, Shockwave lithotripsy
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Kidney Calculi
Ureteral Stent Placement After Ureteroscopy for Renal Stones: A Randomized Controlled Trial
The rationale for this study is to determine if there is a difference in complications among patients undergoing ureteroscopy for renal stones who receive a stent compared to not receiving a stent postoperatively.
- Trial name
- NCT03855787
- Testing
- Ureteroscopy
- Where
- 7 sites in United States, Canada
- Volunteers
- 103 people
- Sponsor
- Vanderbilt University Medical Center
Renal Calculi, Kidney Stones
Clinical Evaluation of BackStop in Patients Undergoing Intraureteric Stone Lithotripsy
The purpose of this clinical study is to evaluate BackStop, a polymer-based device that is intended to be used during ureteroscopic lithotripsy to prevent retrograde stone migration.
- Trial name
- NCT00893282
- Testing
- BackStop, Intracorporeal lithotripsy without the use of an anti-retropulsion device
- Where
- Canada
- Volunteers
- 68 people
- Sponsor
- Pluromed, Inc.
Urolithiasis
A Trial Comparing Efficacy of HM3 Versus F2 Lithotripters for Stone Fragmentation
The older lithotripter, HM3, has over 90% stone-free rate in most studies. However, it's less transportable than the new model, F2.
- Trial name
- NCT00913159
- Testing
- Extracorporeal Shock Wave Lithotripsy (ESWL)
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Washington University School of Medicine
Prostate Cancer, Benign Prostatic Hypertrophy
Evaluation of the NV-VPAC1 Prostate Cancer (PCa) Urine Diagnostic Test in Subjects With Biopsy-confirmed Prostate Cancer, Benign Prostatic Hypertrophy, or Bladder/Kidney Stones.
This is a double-blind, study to evaluate the performance of NV-VPAC1 PCa Urine Diagnostic Test in three distinct populations being treated at the Intermountain Urology Clinic.
- Conditions
- Prostate Cancer, Benign Prostatic Hypertrophy, Bladder Stones, Kidney Stones
- Trial name
- VPAC (NCT03630926)
- Testing
- NV-VPAC1 PCa Urine Diagnostic Test
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Intermountain Health Care, Inc.
Kidney Stone
Follow-Up of Ureteral Stones ≤4 mm
The goal of this clinical trial is to evaluate the proportion of ureteral stones ≤4 mm that pass spontaneously within 4 and 8 weeks and assess if pain, blood test (S-creatinine), stone size, stone location and hydronephrosis can…
- Trial name
- NCT07176026
- Where
- 2 sites in Sweden
- Volunteers
- 1,600 people
- Sponsor
- Region Skane
Kidney Stone, Urolithiasis
Dual-process Mechanisms of Action for sipIT Intervention Effects in Patients With Urolithiasis
The purpose of this study is to clarify the fundamental processes underlying behavior change, maintenance, and adherence during and after a 3-month fluid intake intervention period.
- Conditions
- Kidney Stone, Urolithiasis, Nephrolithiasis
- Trial name
- NCT06269783
- Testing
- sipIT
- Where
- United States
- Volunteers
- 172 people
- Sponsor
- University of Michigan
Renal Calculi
Effects of the Use of Adjuvant Drugs After Extracorporeal Shockwave Lithotripsy (ESWL) in Renal Calculus
The investigators objective is to study if some drugs can improve the success rate of extracorporeal shockwave lithotripsy for renal stones.
- Trial name
- NCT01215708
- Testing
- Tamsulosin
- Where
- Brazil
- Volunteers
- 136 people
- Sponsor
- University of Sao Paulo General Hospital