Clinical trials: Kidney Stones
Pediatric Urolithiasis, Kidney Stone
Standard Versus Flexible and Navigable Suction Ureteral Access Sheath in Pediatric Flexible Ureterorenoscopy for Renal Stones < 2 cm
This randomized controlled trial aims to compare the efficacy and safety of a Flexible and Navigable Suction Ureteral Access Sheath (FANS) versus a standard ureteral access sheath during flexible ureterorenoscopy (FURS) in…
- Conditions
- Pediatric Urolithiasis, Kidney Stone, Nephrolithiasis
- Trial name
- FANS-UAS (NCT07689565)
- Testing
- Standard Ureteral Access Sheath (Boston Scientific)., Flexible and Navigable Suction UAS (ClearPetra).
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Tanta University
Nephrolithiasis, Pediatric Nephrolithiasis
Tubeless vs Tube PCNL in Pediatric Nephrolithiasis
This study is designed to compare two surgical techniques for removing kidney stones in children and adolescents (ages 6-18 years).
- Trial name
- TUBELESS (NCT07183930)
- Testing
- Tubeless Percutaneous Nephrolithotomy (PCNL), Standard Tube Percutaneous Nephrolithotomy (PCNL)
- Where
- Pakistan
- Volunteers
- 640 people
- Sponsor
- Lady Reading Hospital, Pakistan
Kidney Stone
MIP Versus PCNL for Kidney Stone Disease
The decision to use standard percutaneous nephrolithotomy (PCNL) versus mini-percutaneous nephrolithotomy (MIP) has been a subject of much debate in the urological community.
- Trial name
- NCT04767919
- Testing
- Standard Percutaneous Nephrolithotomy (sPCNL), Minimally Invasive Percutaneous Nephrolithotomy (MIP)
- Where
- 6 sites in United States, Canada
- Volunteers
- 75 people
- Sponsor
- University of California, San Diego
Urinary Tract Stone
Effectiveness of WhatsApp Education and Support Messages for Urolithiasis Prevention
Kidney and ureteral stones are a common problem in primary care practice with increasing prevalence over the last few decades. Prevention of recurrent stones (which are usually composed primarily of calcium oxalate) is aimed at…
- Trial name
- StoneApp (NCT05627622)
- Testing
- WhatsApp health education message
- Where
- Israel
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Rabin Medical Center
Kidney Calculi, Ureter Calculi
Comparing Treatment of Urolithiasis Between Disposable and Reusable Ureteroscope
Reusable flexible ureteroscopes are widely used to treat various upper urinary tract diseases including urinary stones. However, they require a long turnover time between procedures because of the sterilization process.
- Trial name
- NCT03040466
- Testing
- reusable fiberoptic ureteroscope, disposable digital ureteroscope
- Where
- United States
- Volunteers
- 180 people
- Sponsor
- University of California, San Francisco
Kidney Stones, Nephrolithiasis
Safety and Effectiveness of the Ultrasonic Propulsion of Kidney Stones
This study tests moving kidney stones using focused ultrasound (referred to as ultrasonic propulsion). The study includes multiple population groups to investigate the ability of our technology to: a) move stone fragments to a…
- Conditions
- Kidney Stones, Nephrolithiasis, Urolithiasis
- Trial name
- NCT02028559
- Testing
- Propulse 1 with C5-2 probe, Propulse 1 with SC-X probe
- Where
- 2 sites in United States
- Volunteers
- 172 people
- Sponsor
- University of Washington
Calculi, Renal, PCNL
Preoperative Prophylactic Fosfomycin Trometamol Versus 5-day Levofloxacin in Prevention of Postpercutaneous Nephrolithotomy Infectious Complications and Sepsis.
A randomized controlled trial comparing the use of preoperative prophylactic single dose fosfomycin trometamol versus levofloxacin in prevention of post-PCNL infectious complications and sepsis.
- Conditions
- Calculi, Renal, PCNL, Infectious Complications
- Trial name
- NCT07355907
- Testing
- PCNL
- Where
- Egypt
- Volunteers
- 210 people
- Sponsor
- Tanta University
Ureteral Stent-Related Symptoms
Alfuzosin and Mirabegron for Double-J Stent Symptoms
This prospective randomized controlled trial investigates the effects of alfuzosin, mirabegron, and their combination on stent-related symptoms and outcomes in patients undergoing DJ stent placement after retrograde intrarenal…
- Trial name
- NCT07018934
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- University of Gaziantep
Ureteral Calculus, Ureterolithiasis
Silodosin Versus Tamsulosin for Treatment of Ureteral Stones
Ureteral calculi, commonly known as kidney stones, are a frequent cause of Emergency Department (ED) visits. These stones can get caught in the ureter (the tube connecting the kidney to the bladder) and cause symptoms including…
- Conditions
- Ureteral Calculus, Ureterolithiasis, Ureteral Stone
- Trial name
- NCT02369744
- Testing
- Silodosin, Tamsulosin
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Albert Einstein Healthcare Network
Adenine Phosphoribosyltransferase Deficiency, AH Amyloidosis
National Registry of Rare Kidney Diseases
The goal of this National Registry is to is to collect information from patients with rare kidney diseases, so that it that can be used for research.
- Conditions
- Adenine Phosphoribosyltransferase Deficiency, AH Amyloidosis, AHL Amyloidosis, AL Amyloidosis
- Trial name
- RaDaR (NCT06065852)
- Where
- United Kingdom
- Volunteers
- 35,000 people
- Sponsor
- UK Kidney Association
Renal Stone, Ureteral Stone
Better Lithotripsy and Ureteroscopy Evaluation of Stenting (BLUES)
This multi-center trial is being completed to compare patient outcomes related to the Imajin silicone stent in comparison to non-silicone polyurethane stents after ureteroscopy.
- Trial name
- BLUES (NCT05026710)
- Testing
- Silicone (Coloplast Imajin Hydro) ureteral stent, Non-silicone (Polyurethane/Percuflex) ureteral stent (any manufacturer)
- Where
- 10 sites in United States
- Volunteers
- 224 people
- Sponsor
- University of Michigan
Renal Stones
Flexible Ureteroscopy Versus ESWL in the Management of Lower Calyceal Stones
to assess safety, efficacy of Flexible ureteroscopy (FURS) holmium:YAG laser lithotripsy (LL) compared to extracorporeal shockwave lithotripsy (ESWL) in management of lower calyceal stones (LC) stones.
- Trial name
- NCT02658942
- Testing
- Ureteroscopy, Shockwave lithotripsy
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Kidney Calculi, Radiation Exposure
Safety and Efficacy of Fluoroscopy-free Technique During Retrograde Intrarenal Surgery for Renal Stones
Aiming to reduce radiation exposure to patients and physicians, the investigators conduct this study protocol to evaluate the possibility of performing retrograde intrarenal surgery (RIRS) under direct visualization without…
- Conditions
- Kidney Calculi, Radiation Exposure, Retrograde Intrarenal Surgery
- Trial name
- NCT05269108
- Testing
- Fluoroscopy-free RIRS, Standard RIRS
- Where
- Egypt
- Volunteers
- 503 people
- Sponsor
- Al-Azhar University
Other Specified Disorders of Kidney and Ureter, Benign Neoplasm of Ureter
Spinal Morphine or Intravenous Lidocaine in Robot-assisted Upper Urologic Surgery
The goal of this clinical trial is to learn whether the addition of spinal analgesia leads to superior recovery in patients undergoing robotic-assisted laparoscopic upper urinary tract surgery under general anesthesia.
- Conditions
- Other Specified Disorders of Kidney and Ureter, Benign Neoplasm of Ureter, Calculus of Kidney and Ureter, Ureter Cancer
- Trial name
- SMILe (NCT06349668)
- Testing
- spinal analgesia with morphine and bupivacaine, lidocaine infusion
- Where
- 3 sites in Sweden
- Volunteers
- 220 people
- Sponsor
- Hans Bahlmann
Nephrolithiasis, Staghorn Calculus
Impact of Tranexamic Acid Use in Percutaneous Nephrolithotomy
This study is a double blinded randomized controlled trial evaluating the impact of tranexamic acid use on the transfusion rate in patients with complex kidney stones undergoing percutaneous nephrolithotomy.
- Trial name
- NCT02966236
- Testing
- Tranexamic Acid
- Where
- Brazil
- Volunteers
- 192 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Analgesia, Postoperative Pain Management
ESP Block for Postoperative Analgesia in URS Surgery
The goal of this clinical trial is to determine whether the erector spinae plane (ESP) block provides better pain relief after flexible ureterorenoscopy (URS) surgery compared to standard analgesia alone.
- Conditions
- Analgesia, Postoperative Pain Management, Nephrolithiasis
- Trial name
- ESPURS (NCT06826833)
- Testing
- Erector Spinae Plane (ESP) Block
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Namik Kemal University
Kidney Stone, Nephrolithiasis
Trial to Assess the Efficacy of EMPAgliflozin and Personalized Dietary Counseling for Kidney STONE Prevention
The aim of this randomized trial with a 2-by-2 factorial design is to test the efficacy of the SGLT2 inhibitor empagliflozin and personalized dietary counseling based on 24-hr urine collection results and dietary assessments for…
- Conditions
- Kidney Stone, Nephrolithiasis, Dietary Exposure
- Trial name
- EMPASTONE (NCT06653738)
- Testing
- Empagliflozin 10 MG, Personalized dietary counseling, Generic dietary counseling
- Where
- 21 sites in France, Germany and 2 more
- Volunteers
- 400 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Urolithiasis, Kidney Stone
Fluoroscopic Guided vs US-guided Percutaneous Nephrolithotripsy for the Treatment of Stone Disease
Randomized comparison of patient outcomes following fluoroscopic guided PCNL versus ultrasound-guided PCNL.
- Conditions
- Urolithiasis, Kidney Stone, Kidney Diseases, Ureteral Calculi
- Trial name
- NCT04606758
- Testing
- PCNL under fluoroscopic control, PCNL under ultrasound control
- Volunteers
- 150 people
- Sponsor
- Astana Medical University
Urinary Stone, Renal Colic
Radiomics and Image Segmentation of Urinary Stones by Artificial Intelligence
Kidney stone disease causes significant morbidity, and stones obstructing the ureter can have serious consequences. Imaging diagnostics with computed tomography (CT) are crucial for diagnosis, treatment selection, and follow-up.
- Conditions
- Urinary Stone, Renal Colic, Obstruction Ureter, Urosepsis
- Trial name
- RISUS_AI (NCT06412900)
- Where
- Norway
- Volunteers
- 522 people
- Sponsor
- Oslo University Hospital
Renal Colic, Ureter Stone
Role of Antihistaminic in Acute Renal Colic Prevent Pain Recurrence and Expulsion of Ureteric Stone ≤ 1cm
Urolithiasis is one of the most common urological diseases. The risk of stone disease ranges between 5% and 12% worldwide. Ureteric stones account for ≈20% of all urinary tract stones and >70% of the ureteric stones are located…
- Trial name
- NCT05150899
- Testing
- Tamsulosin Hcl 0.4Mg Cap, fexofenadine 180 mg Oral tablet
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Assiut University