Clinical trials: Kidney Transplant Candidates, active
Kidney Transplantation, Frailty
Prehabilitation for Kidney Transplant Candidates
This interventional trial seeks to determine the feasibility of wearable sensors to provide data from patients while undergoing supervised exercise.
- Conditions
- Kidney Transplantation, Frailty, Chronic Kidney Insufficiency
- Trial name
- NCT06886256
- Testing
- Polar H10 Heart Rate Monitor, Empatica EmbracePlus, Apple Watch Ultra 2
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- The Methodist Hospital Research Institute
Kidney Transplant
Social Support Counseling Intervention for Kidney Transplant Candidates
Virtual Coaching for Potential Kidney Transplant Patients
- Trial name
- JtT (NCT06147076)
- Testing
- Social Support Network Counseling Intervention
- Where
- United States
- Volunteers
- 86 people
- Sponsor
- Hennepin Healthcare Research Institute
Obesity, Morbid, End Stage Renal Disease
Endoscopic Sleeve Gastroplasty With Endomina® for the Treatment of Obesity in Kidney Transplant Candidates
The aim of this pilot prospective interventional study is to evaluate the efficacy of endoscopic sleeve gastroplasty (ESG) in allowing obese subjects (≥35 kg/m2) with end stage renal disease who need of kidney transplantation to…
- Conditions
- Obesity, Morbid, End Stage Renal Disease, Kidney Transplantation, Endoscopic Sleeve Gastroplasty
- Trial name
- ESGiTXKidney (NCT05917795)
- Testing
- Endoscopic Sleeve Gastroplasty (ESG)
- Where
- Italy
- Volunteers
- 24 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Physical Disability
Virtually Supervised Exercise for Kidney Transplant Candidates
This study is examining whether a virtually supervised exercise program can improve physical function in persons who are awaiting kidney transplant.
- Trial name
- NCT05355545
- Testing
- Virtually supervised exercise, Health education
- Where
- United States
- Volunteers
- 84 people
- Sponsor
- Stanford University
Cardiovascular Diseases, End Stage Renal Disease
Screening for Asymptomatic Coronary Artery Disease in Kidney Transplant Candidates
The Canadian Australasian Randomized Trial of Screening Kidney Transplant Candidates for Coronary Artery Disease (CARSK) will test the hypothesis that eliminating the regular use of non-invasive screening tests for CAD AFTER…
- Conditions
- Cardiovascular Diseases, End Stage Renal Disease, Kidney Transplantation, Dialysis Related Complication
- Trial name
- CARSK (NCT03674307)
- Testing
- No screening, Regular Screening
- Where
- 22 sites in United States, Canada and 2 more
- Volunteers
- 3,306 people
- Sponsor
- University of British Columbia
Kidney Failure, Chronic, Frailty
Evolution of Physical Frailty and Patient-Reported Outcome Measures in Kidney Transplant Candidates: A Mixed-Methods Longitudinal Study Protocol
This study looks at how the physical and emotional health of people changes while they wait for a kidney transplant. Waiting for an organ can take a long time.
- Conditions
- Kidney Failure, Chronic, Frailty, Quality of Life, Kidney Transplantation
- Trial name
- NCT07607041
- Testing
- Longitudinal Frailty Assessment, Electronic Patient-Reported Outcome Measures (ePROMs)
- Volunteers
- 150 people
- Sponsor
- Hospital del Mar
Chronic Kidney Failure, Frailty
Systemic Activation of Inflammasomes and Frailty in Older Candidates to Kidney Transplantation
Kidney transplantation (KT) benefit-risk ratio assessment is a challenge in a growing population of older patients with end-stage kidney disease.
- Conditions
- Chronic Kidney Failure, Frailty, Aging, Inflammation
- Trial name
- INTRA (NCT06887075)
- Testing
- Blood sample, Geriatric assessment standardized
- Where
- 3 sites in France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Bordeaux
Chronic Kidney Disease 5D, Chronic Kidney Disease Stage 5
Kidney Transplant Improvement Through New Exercise Training to Increase Capacity
The goal of this clinical trial is to learn if a home-based exercise program can be safely and feasibly used to improve physical activity and physical function in adults waiting for a kidney transplant.
- Conditions
- Chronic Kidney Disease 5D, Chronic Kidney Disease Stage 5, Kidney Failure, Kidney Failure,Chronic
- Trial name
- KINETIC (NCT07446296)
- Testing
- Exercise Rehabilitation Program with Physical Activity Tracker, Active control
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Pennsylvania
Chronic Kidney Disease (CKD), Kidney Transplant
Remote vs In-Person Prehabilitation for Kidney Transplant Candidates
Patients with advanced chronic kidney disease awaiting deceased-donor kidney transplantation frequently experience progressive functional decline, frailty, reduced mobility, and poor quality of life while on the transplant…
- Conditions
- Chronic Kidney Disease (CKD), Kidney Transplant, Frailty, Prehabilitation
- Trial name
- KIDFIT (NCT07701382)
- Testing
- In-Person Multimodal Prehabilitation, Remote Multimodal Prehabilitation
- Where
- Spain
- Volunteers
- 84 people
- Sponsor
- Hospital Clinic of Barcelona
Highly Sensitized Patients Awaiting Kidney Transplant
OM336 in Sensitized Transplant Candidates
This investigator-initiated, single-arm, open-label Phase IIa pilot study will evaluate the safety, tolerability, pharmacokinetics, pharmacodynamics, and preliminary efficacy of OM336 in highly HLA-sensitized adults with chronic…
- Trial name
- NCT07789431
- Testing
- OM3436
- Where
- 2 sites in Austria, Germany
- Volunteers
- 12 people
- Sponsor
- Medical University of Vienna
Kidney Transplantation Recipients, HLA Sensitization
Safety and Efficacy of BiTE in Desensitization Therapy for Highly Sensitized Kidney Transplant Candidates With cPRA ≥ 90%
This study is a prospective, open-label, two-arm exploratory clinical trial aimed at evaluating the safety and efficacy of Bispecific T-cell Engager (BiTE) therapies in refractory, highly sensitized kidney transplant candidates.
- Trial name
- NCT07689149
- Testing
- BiTE (CD19 x CD3 Bispecific Antibody), BiTE (BCMA x CD3 Bispecific Antibody)
- Volunteers
- 20 people
- Sponsor
- West China Hospital
Latent Tuberculosis, End Stage Renal Disease
One-month Latent Tuberculosis Treatment for Renal Transplant Candidates
This is a prospective, single-center, single-arm, open-label study investigating the safety, compliance and pharmacokinetics of 1-month treatment of Isoniazid, Rifapentine and Vitamin B6 in renal transplant candidates.
- Conditions
- Latent Tuberculosis, End Stage Renal Disease, Renal Transplant Candidate for Right Kidney, Renal Transplant Candidate for Left Kidney
- Trial name
- NCT05411744
- Testing
- 1 month Rifapentine, Isoniazid and Vitamin B6
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Rutgers, The State University of New Jersey
End-Stage Renal Disease Requiring Haemodialysis, Bladder Dysfunction
IMPACT OF DIALYSIS DURATION AND DIURESIS ON BLADDER CAPACITY AND COMPLIANCE IN END STAGE RENAL DISEASE PATIENTS AWAITING RENAL TRANSPLANT
Patients with end-stage renal disease (ESRD) who are on dialysis for a long time may experience bladder problems as their urine output decreases and normal bladder filling is lacking.
- Trial name
- ESRD (NCT07570771)
- Testing
- Observational Assessment
- Where
- Pakistan
- Volunteers
- 87 people
- Sponsor
- Sindh Institute of Urology and Transplantation
Liver Transplant; Complications
Darbepoetin in Patients Candidates for Liver Transplant. (EPO-LT Trial)
This is a national multicenter, randomized clinical trial to evaluate the the efficacy and safety of DP administration in patients on the liver transplant waiting list to reduce intraoperative red blood cell concentrate…
- Trial name
- EPO-LT (NCT07169643)
- Testing
- Darbepoetin (DP)
- Where
- Spain
- Volunteers
- 140 people
- Sponsor
- Fundacion Clinic per a la Recerca Biomédica
Transplant
Simultaneous Prospective Kidney Transplant Assessment in Combined Liver Kidney Candidates
The purpose of the study is to determine how much a persons kidney function recovers after receiving a simultaneous liver kidney transplant.
- Trial name
- RECOVERY (NCT05717842)
- Testing
- Nuclear Medicine Scan
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Indiana University
Kidney Transplant Recipient Response to Shingrix Vaccine, Kidney Failure
Shingrix in Renal Transplant Recipients
The goal of this clinical trial is to learn how well the shingles vaccine (Shingrix) works and how safe it is in adults with kidney failure who are waiting for a kidney transplant, including those who later receive a transplant.
- Conditions
- Kidney Transplant Recipient Response to Shingrix Vaccine, Kidney Failure, Kidney Failure, Chronic, Kidney Transplantation
- Trial name
- NCT04128189
- Testing
- Shingrix
- Where
- 4 sites in United States
- Volunteers
- 132 people
- Sponsor
- University of Colorado, Denver
Kidney Disease, End-Stage, Frailty
Virtual Home-based Physical Pre-habilitation in Kidney Transplant Candidates
The goal of this RCT is to address the feasibility of conducting a 12-week virtual pre-habilitation intervention, which includes exercise and education, in kidney transplant candidates.
- Conditions
- Kidney Disease, End-Stage, Frailty, Transplant;Failure,Kidney
- Trial name
- NCT06089473
- Testing
- Intervention Group: Exercise and education., Usual Care Only
- Where
- 2 sites in Canada
- Volunteers
- 30 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Kidney Disease, Kidney Transplant
Immunological Reset to Allow Access to HLA Compatible Transplantation in Highly Sensitized Kidney Transplant Candidates Through Non-myeloablative Autologous Stemm Cell Transplantation
This is a study for hypersensitized patients who have been waiting for more than 3 years for an offer for a kidney transplant. The objective is to perform a transplant of autologous hematopoietic precursors with the aim of…
- Conditions
- Kidney Disease, Kidney Transplant, Kidney Transplant Candidates
- Trial name
- RESET (NCT06809075)
- Testing
- hematopoietic precursor transplantation (TPHa)
- Where
- Spain
- Volunteers
- 10 people
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute