Clinical trials: Knee, open to volunteers
Total Knee Arthroplasty (Postoperative Pain)
REIKI IN TOTAL KNEE ARTHROPLASTY PATIENTS (REIKI TKA )
Total knee arthroplasty (TKA) is commonly performed to improve mobility and quality of life in patients with degenerative joint diseases.
- Trial name
- REIKI TKA (NCT07442435)
- Testing
- Reiki Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Ondokuz Mayıs University
Prosthetic Joint Infection, Debridement With Prosthesis Retention
Antibiotic-coated Braided Suture Study
The purpose of this study is to evaluate whether the use of antibiotic-coated (triclosan) braided sutures is non-inferior or potentially superior to standard monofilament sutures in patients with prosthetic joint infections…
- Conditions
- Prosthetic Joint Infection, Debridement With Prosthesis Retention, Prosthetic Joint Infections of Hip, Prosthetic Joint Infections of Knee
- Trial name
- NCT07322289
- Testing
- VICRYL™ Plus (Coated VICRYL™ Plus Antibacterial), Polydioxanone (PDS™ II ) Sterile Synthetic Absorbable Surgical Suture-Monofilament
- Where
- United States
- Volunteers
- 142 people
- Sponsor
- University of Miami
Total Knee Replacement, Primary Knee Replacement
Comparison of Pivotal Medial Polyethylene Versus Ultra-congruent in Total Knee Arthroplasty
The aim of this study is to compare the forgotten joint score for the medial pivot polyethylene and ultra-congruent polyethylene which are used in total prosthetic replacement of the knee
- Conditions
- Total Knee Replacement, Primary Knee Replacement, Gonarthrosis
- Trial name
- MEPCAT (NCT06676189)
- Testing
- total knee arthroplasty with medial pivot polyethylene, total knee arthroplasty with ultra-congruent polyethylene
- Where
- France
- Volunteers
- 90 people
- Sponsor
- University Hospital, Clermont-Ferrand
Rehabilitation, Excercise
The ACT-ON: A Geriatric 5-Ms-Guided Physical Therapy Intervention for Knee Osteo-Arthritis in Older Adults.
The study is a Random control trail study conducted at King Khalid University Hospital in Riyadh, Saudi Arabia, focusing on Application of 5 framework in rehabilitation program of knee arthritis.
- Conditions
- Rehabilitation, Excercise, Geriatric, Physical Therapy
- Trial name
- 5Ms/PT/KOA/OA (NCT07640529)
- Testing
- Geriatric 5Ms framework, Exercises PT
- Where
- Saudi Arabia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- King Saud University
Stress
Effect of Audio Book applıcatıon on patıents Blood Pressure, Pulse Rate and anxıety Levels Before Total Knee Replacement Surgery
Before the TDP surgery, the anxiety levels of the patients in the experimental group will be measured by listening to an audio book.
- Trial name
- NCT06905899
- Testing
- audiobook app
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- Beyza Yilmaz
Total Knee Anthroplasty, Epidural Analgesia
Programmed Intermittent Epidural Bolus Versus Continuous Epidural Infusion for Postoperative Analgesia After Total Knee Arthroplasty
The goal of this clinical trial is to compare two different epidural analgesia delivery methods for pain control after total knee arthroplasty in adults undergoing elective surgery.
- Trial name
- NCT07605208
- Testing
- Programmed intermittent epidural bolus 6 ml, continuous epidural infusion
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Sakarya University
Knee Osteoarthritis, Total Knee Arthroplasty
Prediction of Postoperative Outcomes After TKA Using Instrumented Insoles and DNN
This multicenter prospective observational study aims to evaluate whether preoperative clinical variables and wearable sensor-derived gait features can predict postoperative improvement after total knee arthroplasty (TKA).
- Trial name
- NCT07367789
- Testing
- Instrumented Insole Gait Assessment
- Where
- South Korea
- Volunteers
- 200 people
- Sponsor
- Yonsei University
Joint Pain
Genicular Nerve Phenol Neurolysis Versus Radiofrequency Ablation for Pain Relief in Grade 4 Knee Osteoarthritis
The goal of this clinical trial is to compare the efficiency and efficacy of genicular nerves blockade by chemical phenol neurolysis versus radiofrequency ablation in managing pain in patients suffering from grade IV KOA in term…
- Trial name
- NCT06864390
- Testing
- genicular nerve neurolysis
- Volunteers
- 114 people
- Sponsor
- Ain Shams University
To Assess the Feasibility, Visualization Capability, and Optimal Dosing of ICG Fluorescence Imaging for Intraoperative Assessment of Knee Tissue Perfusion
ICG Fluorescence in Knee Arthroscopy Study
The purpose of this study is to first evaluate whether ICG fluorescence angiography can be used to evaluate blood flow of the anterior cruciate ligament (ACL), tendons, and knee structures during an arthroscopic surgery.
- Trial name
- NCT07793266
- Testing
- Intravenous administration of indocyanine green (SPY Agent Green) 2 mL of SPY Agent Green (5.0 mg dose), Intravenous administration of indocyanine green (SPY Agent Green) 3 mL of SPY Agent Green (7.5 mg dose), Intravenous administration of indocyanine green (SPY Agent Green) 4 mL of SPY Agent Green (10 mg dose)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Henry Ford Health System
MRI, Hemophilia
MRI Role in Knee Hemophilic Arthopathy
The aim of this study is to assess role of MRI in detecting synovial, cartilaginous , osseous abnormalities ، bleeding inside knee joint and to use a system for assessing HA as support for therapeutic regimes and for monitoring…
- Conditions
- MRI, Hemophilia, Arthropathy Hemophilic, Arthropathy of Knee
- Trial name
- NCT07233122
- Volunteers
- 95 people
- Sponsor
- Assiut University
Knee Replacement, Total
Knee Replacement Rehabilitation Care Pathways
Previous research has shown that use of rehabilitation (including physical therapy) and the recovery of function after knee replacement surgery may differ depending on patients' race, sex, income or insurance, and geographic…
- Trial name
- NCT07598539
- Testing
- TKA Journey - patient education, Optimized Rehab Scheduling, Usual Rehab
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Pittsburgh
Healthy Japanese Individuals
Verification Study of the Effects of Consumption of the Test Food on the Musculoskeletal System
The goal of this clinical trial is to test the effects of the test products on the locomotor system in healthy Japanese adults with low muscle mass and knee joint discomfort.
- Trial name
- NCT07729657
- Testing
- Food containing NAG and HA, Food containing NAG
- Where
- 2 sites in Japan
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Bloomage Biotechnology Corp., Ltd.
Knee Injuries, Joint Surface Knee Lesions
A Post Approval Multicenter 10 Year Follow-up Observational Trial of Marketed Product - MP01 vs. Surgical Standard of Care (SSOC) Used for the Treatment of Joint Surface Lesions of the Knee
The purpose of the study is to support market adoption and global market access via collection of long-term effectiveness, safety, and radiographic data.
- Trial name
- NCT06916728
- Testing
- Marketed Product - MP01, Surgical Standard of Care
- Where
- 8 sites in United States, Belgium and 4 more
- Volunteers
- 170 people
- Sponsor
- Smith & Nephew, Inc.
Osteoarthritis, Knee Osteoarthritis
Genicular Artery Embolization for Knee Osteoarthritis
Patients will be asked to take part in this research study because they have mild-to-moderate knee osteoarthritis (OA) and were referred clinically for a procedure called Genicular Artery Embolization (GAE).
- Trial name
- NCT07537153
- Testing
- Embosphere Microspheres
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Northwestern University
Pediatric Cancer Patients
Evaluation of an Exercise Intervention During Intensive Medical Treatment in Pediatric Oncology.
The BEPPO study is a Germany-wide clinical trial investigating whether a structured exercise program can improve physical and mental health in children and adolescents undergoing cancer treatment.
- Trial name
- BEPPO (NCT07647471)
- Testing
- Partially-standardised, supervised, continuity-of-care exercise intervention
- Where
- 13 sites in Germany
- Volunteers
- 346 people
- Sponsor
- Universität Duisburg-Essen
Chronic Post-surgical Pain, Chronic Post Operative Pain
Radiofrequency Ablation for the Treatment of Post-knee Arthroplasty Chronic Pain.
Knee osteoarthritis pain is one of the conditions commonly seen in general and specialized medicine. Knee arthroplasty is one of the most successful orthopedic surgeries for the treatment of this disease, significantly improving…
- Conditions
- Chronic Post-surgical Pain, Chronic Post Operative Pain, Chronic Knee Pain
- Trial name
- CSAPG-37 (NCT05920382)
- Testing
- Radiofrequency ablation of peripheral nerves.
- Where
- Spain
- Volunteers
- 86 people
- Sponsor
- Consorci Sanitari de l'Alt Penedès i Garraf
Analgesia, Vastus Lateralis Nerve Block
Analgesic Efficacy of Blocking Nerve to Vastus Lateralis Muscle Versus Lateral Femoral Cutaneous Nerve After Knee Surgeries
This study aims to compare the analgesic efficacy and functional outcomes of blocking the nerve to the vastus lateralis (NVL) muscle versus the lateral femoral cutaneous nerve (LFCN).
- Conditions
- Analgesia, Vastus Lateralis Nerve Block, Lateral Femoral Cutaneous Nerve Block, Knee Surgeries
- Trial name
- NCT06809842
- Testing
- Vastus lateralis nerve block, Lateral femoral cutaneous nerve block
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Kafrelsheikh University
Genu Recurvatum, Crouch Gait
Engaging Kids With Robotic Exoskeletons and Gamification
Conduct a clinical field trial at CHOA's Day Rehab Program using the clinical exoskeleton in conjunction with visual biofeedback with pediatric patients who present with genu recurvatum or crouch gait over 5 rehabilitation visits.
- Trial name
- NCT06647082
- Testing
- Pediatric Knee Exoskeleton
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Georgia Institute of Technology
Knee Osteoarthristis, ACL Injuries
Treatment of Post Traumatic Knee Osteoarthritis With Extracorporeal Shockwave Therapy
This study is recruiting current or former athletes who had ACL reconstruction surgery over a year ago and have been diagnosed with knee osteoarthritis (OA).
- Conditions
- Knee Osteoarthristis, ACL Injuries, Post-Traumatic
- Trial name
- PTOA Knee (NCT06686680)
- Testing
- extracorporeal shockwave therapy (ESWT)
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Spaulding Rehabilitation Hospital
Osteoarthritis, Knee
Ultrasound-Guided Pulsed Radiofrequency In The Treatment Of Patients With Osteoarthritis Knee (USPRFGENOAK)
The purpose of this study is to determine if patients with chronic painful knee osteoarthritis experience meaningful and long-term improvement in pain, function, and analgesic use after ultrasound-guided pulsed radiofrequency of…
- Trial name
- USPRFGENOAK (NCT02915120)
- Testing
- Real Pulsed Radiofrequency
- Where
- Spain
- Volunteers
- 142 people
- Sponsor
- Hospital Son Llatzer
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