Clinical trials: Knee
Prosthesis User, Amputation
Clinical Investigation (Beta) of Power Knee Mainstream - Dynamic
Prospective two group cross over investigation, comparing the investigational device (Power Knee, a powered microprocessor controlled prosthetic knee) and subjects prescribed microprocessor prosthetic knee (MPK).
- Trial name
- NCT04787627
- Testing
- Power Knee
- Where
- 2 sites in United States
- Volunteers
- 17 people
- Sponsor
- Össur Iceland ehf
Hyperglycemia, Hypercholesterolemia
Glucose Metabolism Disorders and Metabolic Syndrome Before and After Primary Hip and Knee Replacement
Osteoarthritis patients undergoing primary hip and knee replacement are followed-up and changes in their glucose metabolism and other metabolic parameters (obesity, cholesterol levels) are examined.
- Conditions
- Hyperglycemia, Hypercholesterolemia, Persistent Postoperative Pain, Hip Replacement
- Trial name
- HyTe-2 (NCT01743313)
- Where
- Finland
- Volunteers
- 155 people
- Sponsor
- Coxa, Hospital for Joint Replacement
Arthroplasty, Replacement, Knee
Triathlon® Cruciate Retaining (CR) Total Knee System Outcomes Study
The purpose of this study is to evaluate the clinical outcomes (range of motion, pain, function, radiographic stability, and health related quality of life) of patients receiving the Triathlon® Cruciate Retaining (CR) Total Knee…
- Trial name
- NCT00957723
- Testing
- Triathlon® CR Total Knee System
- Where
- 11 sites in United States
- Volunteers
- 419 people
- Sponsor
- Stryker Orthopaedics
Knee Arthroscopy
Outpatient Total Knee Arthroscopy (TKA): Comparison of Postoperative Recovery Versus a Conventional Hospitalization
Outpatient TKA is a controversial topic due to concerns about its safety as an outpatient procedure, and remains a marginal procedure.
- Trial name
- PTG (NCT07276061)
- Where
- France
- Volunteers
- 440 people
- Sponsor
- University Hospital, Strasbourg, France
Knee Arthropathy
Post-market Clinical Follow-up on the balanSys UNI Knee Prosthesis Implanted With a Spacer Block Surgical Technique
The purpose of the study is the evaluation of the clinical and radiological long-term performance of the balanSys UNI fix in a multicenter routine clinical setting.
- Trial name
- NCT04598568
- Testing
- balanSys UNI
- Volunteers
- 116 people
- Sponsor
- Mathys Ltd Bettlach
Knee Injuries
Knee Alignment Contributions to Anterior Cruciate Ligament (ACL) Injury
This study evaluates the the anatomic factors of the knee that may predispose to ACL injury.
- Trial name
- NCT00855023
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- The Orthopaedic Center, Maryland
Peripheral Artery Disease
Evaluating the Safety and Efficacy of the G-stream® Drug-Eluting Stent in the Above-the-Knee Femoropopliteal Artery
A multicenter, randomized, controlled, superiority clinical trial to evaluate the efficacy and safety of drug-eluting peripheral arterial stent system（G-stream） in the treatment of femoropopliteal artery stenosis or occlusion.
- Trial name
- G-streamPAD (NCT05780359)
- Testing
- Drug eluting stent, drug coating balloon
- Where
- China
- Volunteers
- 280 people
- Sponsor
- Shenzhen Salubris Pharmaceuticals Co., Ltd.
Knee Osteoarthritis, Lower Extremity Biomechanics
Motor Learning in Knee Osteoarthritis
Non-surgical treatment options, like exercise therapy, show excellent short-term effects regarding pain reduction and improvement of knee function. However, mid- and long-term effects are missing so far.
- Conditions
- Knee Osteoarthritis, Lower Extremity Biomechanics, Physiotherapy
- Trial name
- MLKOA (NCT04445350)
- Testing
- External Focus Of Attention, Internal Focus Of Attention
- Where
- Austria
- Volunteers
- 50 people
- Sponsor
- St. Pölten University of Applied Sciences
Quadriceps Function Monitored With Electromyography
Compare the Quadriceps Function of Adductor Canal Block Versus Femoral Nerve Block With Electromyography Following Total Knee Arthroplasty
Adductor canal block and femoral nerve block are the most commonly used nerve blocks for pain control after total knee arthroplasty.
- Trial name
- NCT04778774
- Testing
- Nerve block
- Where
- Taiwan
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Orthostatic Hypotension, Orthostatic Intolerance
Postoperative Incidence of Orthostatic Intolerance and Hypotension in Primary Unicompartmental Knee Arthroplasty (UKA)
Incidence and pathophysiologic hemodynamics of orthostatic intolerance and orthostatic hypotension in patients undergoing UKA
- Conditions
- Orthostatic Hypotension, Orthostatic Intolerance, Postoperative Complications
- Trial name
- NCT04195360
- Testing
- Standardized mobilization procedure
- Where
- Denmark
- Volunteers
- 42 people
- Sponsor
- Copenhagen University Hospital, Hvidovre
Temperature Change, Body
Effect of Pressure on Skin Temperature When Using a Cryocompression Device
Cryotherapy after surgery is widely utilised and has numerous practical applications for post-operative rehabili-tation. Previous research has suggested that during cold therapy, the skin temperature of the knee should be reduced…
- Trial name
- NCT05454982
- Testing
- Cryocompression
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Winchester
Chondral Defect, Osteochondral Defect
An Observational, Prospective Study of Patients With Chondral and/or Osteochondral Defects of the Knee Treated With NAMIC
It is a prospective observational study of hospital cases. The objective is to determine the decrease of lesion size and the regeneration of chondral tissue in femoral condyle cartilage defect treated with NAMIC.
- Trial name
- KNAMIC (NCT03625180)
- Testing
- NAMIC: nanofractured autologous matrix-induced chondrogenesis
- Where
- Spain
- Volunteers
- 24 people
- Sponsor
- Jordi Villalba Modol
Knee Osteoarthritis
Clinical Cohort Study of Knee Arthroplasty Assisted by Digital Technology
Through this cohort study, previous clinical data can be systematically reviewed and supplemented through clinical follow-up. Prospective enrollment and follow-up observation of subsequent patients can also be carried out to…
- Trial name
- NCT06010979
- Testing
- conventional intrumentation assisted knee arthroplasty, computer navigation assisted knee arthroplasty, robotic system assisted knee arthroplasty
- Where
- China
- Volunteers
- 12,000 people
- Sponsor
- Tian Hua
Knee Osteoarthritis (Knee OA)
Evaluation of the Effects of Pulsed Electromagnetic Field on Inflammatory Knee Osteoarthritis
This study will assess the efficacy of pulsed electromagnetic field therapy in patients with inflammatory knee osteoarthritis confirmed by MRI-detected effusion-synovitis.
- Trial name
- NCT07443462
- Testing
- Pulsed Electromagnetic Field (PEMF) Therapy
- Volunteers
- 50 people
- Sponsor
- The Hong Kong Polytechnic University
Osteoarthritis, Knee, Obesity
A Hip Flexion Feedback System for Exercise Monitoring in Individuals With Osteoarthritis and Obesity
Exercise is very important for living healthier and longer lives. For people with obesity and osteoarthritis, exercise is even more important because it can help them feel less pain in their joints.
- Trial name
- NCT05997862
- Testing
- HFFS
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- University of Southern Mississippi
Hip Prosthesis Infection, Knee Prosthesis Infection
CERAMENTTM|G and V in the Management of Hip and Knee Arthroplasty Revisions (Revision Arthroplasty Italy)
Open-label, multicentre, prospective cohort, observational clinical trial with a retrospective control group to evaluate the effectiveness and safety of CERAMENTTM| G or V used for filling of bone defects in the tibia and / or…
- Trial name
- NCT03389646
- Testing
- CERAMENT G V
- Where
- Italy
- Volunteers
- 135 people
- Sponsor
- I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio
Sleep, Knee Osteoarthritis
Magnesium-L-Threonate for Sleep Quality Post-Arthroplasty
The study team is conducting a study to see if Magnesium-L-Threonate (MgT) can help improve how well participants sleep and reduce pain after total joint replacement surgery
- Trial name
- NCT06902285
- Testing
- Magnesium Threonate, Control
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- University of Miami
Anterior Cruciate Ligament Rupture
BFRT in Adolescents After ACL Reconstruction
This is an interventional study that will examine effects of blood flow restriction training (BFRT) in adolescents aged 12-18 after anterior cruciate ligament reconstruction surgery (ACLR).
- Trial name
- NCT04390035
- Testing
- Blood Flow Restriction using Delfi Personalized Tourniquet System
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Children's Healthcare of Atlanta
Cardiovascular Complication, Pulmonary Embolism
MACE and PE in Elective Primary TKA & THA
This study ought to identify the occurence of the major adverse cardiovascular events (MACE) and the pumonary emoblism (PE) in patients undergoing elective primary THA \& TKA
- Conditions
- Cardiovascular Complication, Pulmonary Embolism, Stroke, Transient Ischemic Attack
- Trial name
- NCT05116280
- Where
- Greece
- Volunteers
- 200 people
- Sponsor
- University of Thessaly
Knee Arthroscopic Surgery, Analgesia
Ultrasound Guided Femoral Nerve Block Versus Adductor Canal Block by Using Bupivacaine and Magnesium Sulphate for Post-Operative Analgesia
Ultrasound Guided Femoral Nerve Block versus Adductor Canal Block by Using Bupivacaine and Magnesium Sulphate
- Conditions
- Knee Arthroscopic Surgery, Analgesia, Femoral Nerve Block (FNB)
- Trial name
- NCT07838480
- Testing
- Group I: control group, Group II: Ultrasound Guided Femoral Nerve Block, group III : Adductor Canal Block group
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Tanta University