Clinical trials: Knee Arthritis
Osteoarthritis, Knee
The Effect of Cryotherapy in Pain Control, Function and Quality of Life in Individuals With Knee Osteoarthritis
The purpose of this study is to verify the effect of cryotherapy in pain control, function and quality of life in individuals with knee osteoarthritis.
- Trial name
- NCT02725047
- Testing
- Cryotherapy
- Where
- Brazil
- Volunteers
- 60 people
- Sponsor
- Universidade Federal de Sao Carlos
Arthritis Knee
Preoperative Radiographic Evaluation of Medial Tibiofemoral Knee Osteoarthritis
Observational study.
- Trial name
- RX-FTI (NCT03704558)
- Sponsor
- Rennes University Hospital
Arthritis Knee, Knee Osteoarthritis
The Effect of a Methylprednisolone Taper on Outcomes Following Total Knee Arthroplasty
Pain control and early range of motion following total knee arthroplasty are essential for patient satisfaction. Intraoperative steroids (dexamethasone) have been shown to have a significant effect in controlling acute pain…
- Conditions
- Arthritis Knee, Knee Osteoarthritis, Pain, Postoperative
- Trial name
- NCT06489626
- Testing
- Methylprednisolone 4 milligram Tab, Dexamethasone injection
- Where
- 2 sites in United States
- Sponsor
- F. Johannes Plate
Osteoarthritis, Knee
Efficacy of High-Intensity Laser Therapy in Early-Stage Symptomatic Knee Osteoarthritis
This randomized, double-blind, sham-controlled clinical trial evaluated the effectiveness of high-intensity laser therapy (HILT) in patients with early-stage symptomatic knee osteoarthritis.
- Trial name
- HILT-ESCOA (NCT07859878)
- Testing
- High-Intensity Laser Therapy (HILT), Standardized Home Exercise Program
- Where
- Turkey (Türkiye)
- Volunteers
- 39 people
- Sponsor
- Ege University
Osteoarthritis of Knee, Osteoarthritis Of Hip
Mobile Technology to Support Physical Therapy Exercise
Osteoarthritis is the leading cause of disability in the U.S, particularly in older adults. Exercise is an evidence-based treatment option that improves pain and disability outcomes in adults with osteoarthritis, but adherence to…
- Trial name
- MyTherEx (NCT03428893)
- Testing
- Mobile Application
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Vermont
Knee Osteoarthritis
Muscle Activation in Knee Osteoarthritis
Muscle activity, as a possible fundamental cause of functional limitation, has been extensively investigated in knee osteoarthritis (KOA).
- Trial name
- NCT05870033
- Testing
- Electromyography (EMG) measurement
- Where
- Hungary
- Volunteers
- 70 people
- Sponsor
- University of Pecs
Knee Osteoarthritis, Total Knee Arthroplasty
Prediction of Postoperative Outcomes After TKA Using Instrumented Insoles and DNN
This multicenter prospective observational study aims to evaluate whether preoperative clinical variables and wearable sensor-derived gait features can predict postoperative improvement after total knee arthroplasty (TKA).
- Trial name
- NCT07367789
- Testing
- Instrumented Insole Gait Assessment
- Where
- South Korea
- Volunteers
- 200 people
- Sponsor
- Yonsei University
Osteoarthritis, Knee, Arthropathy of Knee
Total Knee Arthroplasty: Fast Track Protocol is the Future?
Fast-track total knee arthroplasty (TKA) is a well-established concept including optimized logistics and evidence-based treatment, focusing on minimizing surgical stress and improved post-operative recovery.
- Trial name
- FastTrack-G (NCT03869996)
- Testing
- fast track care protocol, standard care protocol
- Where
- Italy
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Istituto Ortopedico Rizzoli
Total Knee Replacement
Qualitative Interviews With Healthcare Professionals
PLANNING PHASE- Qualitative interviews with Healthcare Professionals to assist in the development of a new Patient Reported Outcome Measure (PROM) to assess patient's emotional wellbeing, and perceptions of Total Knee Replacement…
- Trial name
- NCT05597046
- Testing
- Interview
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Invibio Ltd
Primary Total Knee Arthroplasty, Intraosseous Morphine Injection
Effectiveness of Adding Morphine to Intraosseous Vancomycin for Pain Control in Total Knee Arthroplasty
Study investigators propose to investigate if a bony injection of pain medication during a knee replacement will help pain levels following primary knee replacement surgery. To investigate this, 86 patients will be enrolled.
- Conditions
- Primary Total Knee Arthroplasty, Intraosseous Morphine Injection, Knee Osteoarthritis
- Trial name
- NCT06716749
- Testing
- Morphine, Vancomycin
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Carilion Clinic
Knee Osteoarthritis, Knee Pain Chronic
Genicular Artery Embolization (GAE) for Osteoarthritic Knee Pain
The objective of this investigation is to evaluate the safety of the geniculate artery embolization (GAE) procedure with HydroPearl® Microspheres in 30 patients with knee pain caused by osteoarthritis with 24 months follow-up.
- Conditions
- Knee Osteoarthritis, Knee Pain Chronic, Knee Pain Swelling, Knee Arthritis
- Trial name
- NCT04472091
- Testing
- Genicular artery embolization (GAE)
- Where
- United States
- Sponsor
- Andrew Picel
Total Knee Arthroplasty, Knee Disease
Open Label Study to Collect Clinical Data to Document Clinical Performance and Safety in Total Knee Arthroplasty
The purpose of this study is to evaluate clinical performance and safety in total knee arthroplasty using HLS implants.
- Conditions
- Total Knee Arthroplasty, Knee Disease, Total Knee Replacement, Osteo Arthritis Knee
- Trial name
- NCT04727060
- Testing
- patient with knee arthroplasty
- Where
- France
- Volunteers
- 2,146 people
- Sponsor
- Corin
Knee Osteoarthritis, Osteo Arthritis Knee
Microfragmented Adipose Tissue Compared to Saline Injection for the Treatment of Knee Osteoarthritis
The goal of this clinical trial is to examine the effect of a single autologous, intra-articular injection of MFat versus saline injection for the treatment of pain and function associated with K/L grade 2/3 knee Osteoarthritis.
- Trial name
- ARISE2 (NCT06121882)
- Testing
- Microfragmented Adipose Tissue derived using the Lipogems® System, Saline Injection
- Where
- 16 sites in United States
- Volunteers
- 173 people
- Sponsor
- Lipogems International spa
Osteoarthritis of the Knee
Effect Of Meloxicam Versus Placebo In Mainland Chinese Patients With Osteoarthritis Of The Knee
This study is to validate the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) tool in mainland Chinese patients with osteoarthritis of the knee .
- Trial name
- NCT01430559
- Testing
- Meloxicam
- Where
- 25 sites in China
- Volunteers
- 408 people, healthy volunteers welcome
- Sponsor
- Pfizer
Osteoarthritis, Hip, Osteoarthritis, Knee
Evaluation of Teleconsulting on Rehabilitation After Hip and Knee Surgical Procedures
The objective of this study is to assess the medical and economic relevance of teleconsulting for Rehabilitation After Hip and Knee Surgical Procedures.
- Trial name
- SSRHAD (NCT02229279)
- Testing
- Teleconsulting
- Where
- France
- Volunteers
- 430 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Osteoarthritis
Treatment of Knee Osteoarthritis by Intra-articular Injection of Bone Marrow Mesenchymal Stem Cells
Purpose: To determine the safety, feasibility and effectiveness (clinical and radiological) of intra-articular administration of autologous mesenchymal stem cells (MSCs) in patients with knee osteoarthritis.
- Trial name
- NCT02123368
- Testing
- Hyaluronic acid, 10 million Bone marrow mesenchimal stem cells, 100 million Bone marrow mesenchimal stem cells
- Where
- 2 sites in Spain
- Volunteers
- 30 people
- Sponsor
- Clinica Universidad de Navarra, Universidad de Navarra
Knee Osteoarthritis
A Powered Exoskeleton for Veterans With Knee OA
The purpose of this study is to evaluate in-laboratory mobility outcomes, pain perception, and user satisfaction with the Keeogo , a robotic exoskeleton for providing assistance on knees during stand and swing for a population…
- Trial name
- NCT04653896
- Testing
- Keeogo
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- VA Office of Research and Development
Osteoarthritis, Knee
Intraarticular Glucose Versus Hyaluronic Acid Injection for Knee Osteoarthrosis
The study is a prospective, randomized controlled, double-blind study. The enrolled patients were randomly divided into two groups: the intraarticular glucose group and the intraarticular HA group.
- Trial name
- NCT03690232
- Testing
- glucose water, hyaluronic aicd
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Osteoarthritis
A Trial of SB-061 in Osteoarthritis of the Knee
This study evaluates a novel agent, SB-061, for the treatment of osteoarthritis of the knee. Half of the patients will receive the agent via intra-articular injection and half will receive a placebo injection.
- Trial name
- MODIFY-OA (NCT02802709)
- Testing
- SB-061
- Where
- 2 sites in Estonia
- Volunteers
- 90 people
- Sponsor
- Symic OA Co.
Osteo Arthritis of the Knee
Minimal-Incision Technique With Modified Tracking Pin Placement Versus Standard Robotic-Assisted Total Knee Arthroplasty
This randomized controlled trial will compare a minimal-incision and soft-tissue-preserving (MISI) technique with the standard surgical technique in patients undergoing robotic-assisted total knee arthroplasty for knee…
- Trial name
- MISI (NCT07765771)
- Testing
- MISI Robot-Assisted Total Knee Arthroplasty, Standard Robotic-Assisted Total Knee Arthroplasty
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- Hallym University Kangnam Sacred Heart Hospital