Clinical trials: Knee Arthritis Disease
Arthropathy of Knee, Arthritis Knee
Validation of Consumer Activity Monitors in Postoperative Total Arthroplasty Patients
Mobilization and rehabilitation are essential components of a successful functional recovery following total hip and knee arthroplasties. Currently, we have no good measure of how mobile patients are after their surgery.
- Conditions
- Arthropathy of Knee, Arthritis Knee, Arthritis, Degenerative
- Trial name
- NCT03958370
- Testing
- Fitbit
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Benaroya Research Institute
Knee Osteoarthritis
Effects of IMT on Cardiopulmonary Endurance and Functional Mobility in KOA
The purpose of the study is to investigate whether adding Inspiratory Muscle Training (IMT) to the usual treatment of patients with knee osteoarthritis improves their cardiopulmonary endurance and functional mobility more than…
- Trial name
- IMT (NCT07738627)
- Testing
- POWERBREATH
- Where
- Pakistan
- Volunteers
- 65 people
- Sponsor
- Riphah International University
Knee Osteoarthritis, Hip Osteoarthritis
Arabic Version of the ICOAP Questionnaire
A study to translate and cross-culturally adapt the Intermittent and Constant Osteoarthritis Pain (ICOAP) measurement tool into the Arabic language, and assess its psychometric properties.
- Trial name
- NCT04648956
- Testing
- Standard treatment
- Where
- Saudi Arabia
- Volunteers
- 99 people
- Sponsor
- Prince Sultan Military College of Health Sciences
Knee Osteoarthritis
Autologous Stromal Vascular Fraction of Cells for Treatment of Knee Articular Cartilage Dystrophy
Stromal vascular fraction of cells (SVF) will be extracted from lipoaspirate by enzymatic digestion. SVF will be administered in a single dose intraarticularly 4 weeks after arthroscopic debridement.
- Trial name
- NCT02827851
- Testing
- Liposuction, SVF isolation, Intraarticular administration of autologous SVF
- Where
- 4 sites in Russia
- Volunteers
- 200 people
- Sponsor
- Central Clinical Hospital w/Outpatient Health Center of Business Administration for the President of Russian Federation
Knee Osteoarthritis, Chitosan Nanoparticles Gel
Extracorporeal Shockwave Versus Phonophoresis Using Chitosan-Nanoparticles Gel on Functional and Anatomical Changes Detected With Artificial Intelligence Based Texture Analysis Algorithm in Knee Osteoarthritis Patients: A Double Blind Randomized Controlled Trial
A parallel double blinded randomized controlled clinical trial (RCT) with a 1:1:1 allocation will be conducted in an orthopedic clinic in Cairo and Giza Governments - Egypt.
- Conditions
- Knee Osteoarthritis, Chitosan Nanoparticles Gel, Artificial Intelligence Texture Analysis Bases Algorithm, Subchondral Bone Changes (Anatomical Changes)
- Trial name
- NCT06567301
- Testing
- Ultrasound therapy combined with Chitosan nanoparticles gel
- Where
- 2 sites in Egypt
- Volunteers
- 120 people
- Sponsor
- Cairo University
Osteoarthritis, Knee
Inpatient vs Outpatient Total Knee Replacement
This is a prospective cohort study comparing standard inpatient (overnight hospital stay) total knee arthroplasty with same day discharge.
- Trial name
- NCT04228731
- Testing
- Outpatient, Inpatient
- Where
- Canada
- Volunteers
- 123 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Osteoarthritis, Knee, Osteoarthritis, Hip
Increasing Physical Activity in Older Adults With Osteoarthritis Pain: Examining a Brief Behavioral Intervention
The purpose of this study is to evaluate how older adults might benefit from sessions that teach behavioral coping skills for increasing physical activity and reducing interference from arthritis pain.
- Trial name
- NCT04490395
- Testing
- Engage PA, Treatment as Usual plus (TAU+)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Duke University
Knee Osteoarthritis
Safety Study of PTP-001 for Treating Knee Osteoarthritis
Evaluation of safety, tolerability, and efficacy of a single intra-articular (IA) injection of PTP-001, an allogeneic placental tissue particulate, in individuals with knee osteoarthritis (OA).
- Trial name
- NCT04632966
- Testing
- Biological: PTP-001
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- Bioventus LLC
Knee Osteoarthritis
Efficacy of Dehydrated Cell and Protein Concentrate Versus Corticosteroid
To compare the efficacy of Ascent injection versus corticosteroid injection in treating knee osteoarthritis.
- Trial name
- NCT03710005
- Testing
- Ascent, Standard
- Where
- 4 sites in United States
- Volunteers
- 51 people
- Sponsor
- StimLabs
Knee Osteoarthritis
Safety, Tolerability and Pharmacokinetics of Intraarticular 4P004 Single Dose in Patient With KL 2-4 Osteoarthritic Knee
This phase I study is a multicenter, randomized, double-blind, placebo-controlled study to assess the safety and tolerability of single ascending dose of IA 4P-004 in participants, Between 18 and 80 years of age, with target knee…
- Trial name
- LASARE (NCT05419856)
- Testing
- 4P-004
- Where
- 3 sites in Belgium
- Volunteers
- 34 people
- Sponsor
- 4Moving Biotech
Knee Osteoarthritis
Trial Comparing Alignment Techniques - RSA of ATTUNE Knee System
The purpose of this study is to compare migration patterns between mechanical and anatomic alignment surgical techniques for the Attune S+ CR-FB knee system using model-based RSA over the first 2 post-operative years.
- Trial name
- NCT04079751
- Testing
- Neutral Mechanical Alignment, Anatomical Alignment
- Where
- 2 sites in Canada
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Canadian Radiostereometric Analysis Network
Osteoarthritis, Knee
Effect of Nonsteroidal Anti-Inflammatory Drug Restriction on the Efficacy of Platelet-Rich Plasma in Knee Osteoarthritis
The goal of this randomized clinical trial is to learn whether taking ibuprofen, a nonsteroidal anti-inflammatory drug, after a platelet-rich plasma (PRP) injection changes pain relief and knee function in adults with knee…
- Trial name
- NCT07766330
- Testing
- Leukocyte-Rich Platelet-Rich Plasma, ibuprofen, Acetaminophen
- Where
- Brazil
- Volunteers
- 90 people
- Sponsor
- Federal University of São Paulo
Total Knee Arthroplasty
Effection of Total Knee Arthroplasty on Knee Joint
The aim of this study is to evaluate the joint position sense of individuals diagnosed with knee osteoarthritis and who have undergone unilateral total knee arthroplasty surgery, and to examine the effect of joint position sense…
- Trial name
- NCT05965765
- Testing
- Total knee arthroplasty, osteoarthritis without surgery, control group
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- KTO Karatay University
Knee Osteoarthritis
Investigation of the Effect of Superimposed Neuromuscular Electrical Stimulation in Patients With Knee Osteoarthritis.
The aim of the study is to investigate the effects of superimposed neuromuscular electrical stimulation with active contraction on physical function, muscle and joint structure, functionality, and quality of life in patients with…
- Trial name
- NCT06277570
- Testing
- conventional physiotherapy, NMES, Superimposed NMES
- Where
- Turkey (Türkiye)
- Volunteers
- 63 people
- Sponsor
- Gulhane School of Medicine
Knee Osteoarthritis
Dry Needling Treatment for Knee Osteoarthritis
The population affected by degenerative knee arthritis is very large. The investigator performed dry needle (DN) treatments with acupuncture needles.
- Trial name
- NCT03639441
- Testing
- dry needling, Transcutaneous electrical nerve stimulation
- Where
- Taiwan
- Volunteers
- 33 people
- Sponsor
- China Medical University Hospital
Knee Osteoarthritis
Cingal Study for Knee Osteoarthritis
The purpose of this study is to see if a single injection of Cingal into the knee provides safe relief of pain caused by osteoarthritis.
- Trial name
- NCT01891396
- Testing
- Hyaluronic Acid and TH (Cingal®), Hyaluronic Acid (Monovisc®), Saline
- Where
- 27 sites in Bulgaria, Canada and 3 more
- Volunteers
- 368 people
- Sponsor
- Anika Therapeutics, Inc.
Osteoarthritis
Chinese Herbal Fumigation With Acupuncture for the Knee Osteoarthritis
To evaluate the effect of fumigation in conjunction with acupuncture for knee osteoarthritis, participators were collected from acupuncture and Chinese traumatology clinic at Linsen Chinese Medicine and Kunming Branch, Taipei…
- Trial name
- NCT03659370
- Testing
- Fumigation, Acupuncture
- Where
- Taiwan
- Volunteers
- 45 people
- Sponsor
- Taipei City Hospital
Knee Osteoarthritis, Metformin
Effect of Metformin as Add-on Therapy to Ibuprofen on Disease Activity in Knee Osteoarthritis Patients.
The goal of this randomized, double blind, placebo-controlled clinical trial is to learn about, the effect of metformin compared with placebo-controlled group on disease activity and interleukin-6 level in patients with knee…
- Trial name
- NCT06126029
- Testing
- Metformin 500 Mg extended release Oral Tablet
- Where
- Bangladesh
- Volunteers
- 68 people
- Sponsor
- Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh
Gonarthrosis
Dexmedetomidine Infusion and Iscemia and Reperfusion Injury
The effect of deksmedetomidine infusion on ischemia-reperfusion injury related to tourniquet application during total knee replacement will be evaluated by malondialdehyde and total antioksidant status.
- Trial name
- NCT07875231
- Testing
- Dexmedetomidine, saline
- Volunteers
- 60 people
- Sponsor
- Diskapi Yildirim Beyazit Education and Research Hospital
Osteoarthritis of the Knee
Effect of Glucosamine or Ibuprofen Combined With Physical Training in Patients With Knee-Osteoarthritis
The investigators will investigate the effect of glucosamine or ibuprofen combined with 12 weeks of muscle strength-training in patients with knee-osteoarthritis.
- Trial name
- NCT00833157
- Testing
- glucosamine sulphate, ibuprofen
- Volunteers
- 36 people
- Sponsor
- Bispebjerg Hospital
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.