Clinical trials: Knee Arthritis Disease
Knee Osteoarthristis
Femoral Nerve Mobilization for Patients With Knee Osteoarthritis
Background: Knee osteoarthritis (KO) is considered as a cause of disability among the elderly, causing pain, reduced quality of life, and decreased functionality.
- Trial name
- RCT (NCT07329205)
- Testing
- traditional physical therapy, Femoral nerve mobilization
- Where
- Saudi Arabia
- Volunteers
- 50 people
- Sponsor
- Prince Sattam Bin Abdulaziz University
Osteoarthritis, Knee
P.F.C. Sigma Fixed Versus P.F.C. RP Mobile Bearing Total Knee Systems
This post-market clinical follow-up study was designed to compile long-term knee replacement outcomes of the PFC Sigma fixed and PFC Sigma mobile Rotating Platform (RP) knee systems.
- Trial name
- NCT00208286
- Testing
- PFC Sigma Fixed Bearing, PFC Sigma Mobile Bearing
- Where
- United Kingdom
- Volunteers
- 120 people
- Sponsor
- DePuy International
Pain, Osteoarthritis
Impact of Peripheral Nerve Blockade on Outcomes After Total Knee Replacement
Pain is common after knee replacement surgery and can impact a variety of patient outcomes. Peripheral nerve blocks provide improved pain control and may improve function.
- Trial name
- NCT02742961
- Testing
- Peripheral nerve block
- Where
- Canada
- Volunteers
- 178,214 people
- Sponsor
- Ottawa Hospital Research Institute
Osteoarthritis, Knee, Osteoarthritis
Low Intensity Pulsed Ultrasound Versus High Intensity Continuous Ultrasound Therapy in Knee Osteoarthritis
To compare the effects of low intensity pulsed ultrasound with high intensity continuous ultrasound in knee osteoarthritis
- Conditions
- Osteoarthritis, Knee, Osteoarthritis, Rheumatic Diseases, Musculoskeletal Diseases
- Trial name
- NCT04406337
- Testing
- Low intensity pulsed ultrasound, High intensity continuous ultrasound
- Where
- Burma
- Volunteers
- 86 people
- Sponsor
- Ministry of Health and Sports, Myanmar
Osteoarthritis of Knee
Efficacy of Intra-Articular Injection of Etanercept for Moderate and Severe Knee Osteoarthritis
Primary aim: evaluate efficacy of intra-articular injection of etanercept for moderate and severe knee osteoarthritis. Second aim: investigate the potentiality of serum cytokines (TNF-α, Interleukin 1-α (IL1-α), IL1-β, matrix…
- Trial name
- EIAIETNKOA (NCT02722772)
- Testing
- Etanercept, Health education, exercise and diet guidance
- Where
- China
- Volunteers
- 60 people
- Sponsor
- First Affiliated Hospital of Harbin Medical University
Knee Osteoarthritis, Arthroplasty Complications
Treadmill Perturbation Training for Fall Prevention After Total Knee Replacement
The goal of this clinical trial is to learn about preventing falls in people who have total knee replacement surgery using treadmill perturbation training.
- Trial name
- NCT05736666
- Testing
- Treadmill-based perturbation training, Education Control
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- University of Illinois Chicago
Knee Osteoarthritis
Tidal Irrigation Versus Intra-articular Steroid Injection in the Treatment of Knee Osteoarthritis
Previous studies have indicated that patient expectations, beliefs and preferences may have an impact on treatment outcomes. The KIVIS study was primarily designed to compare two effective treatments for knee osteoarthritis…
- Trial name
- NCT01303666
- Testing
- Intra-articular CSI, TI of the knee
- Volunteers
- 150 people
- Sponsor
- Portsmouth Hospitals NHS Trust
Knee Arthroplasty
Clinical and Economic Comparison of Robot Assisted Versus Manual Knee Replacement
The purpose of this study is to document and compare the surgical and after surgery costs, recovery time, and outcomes of two procedure types: Robotic assisted surgery replacing one compartment of the knee Manual (robot is not…
- Trial name
- NCT01705886
- Testing
- Total Knee Arthroplasty, MAKO® Robot Assisted Medial Knee Arthroplasty, RESTORIS Multicompartmental Knee System
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- Northwest Surgical Specialists, Vancouver
Knee Osteoarthritis
Retrospective Evaluation of the Long-term Effectiveness of the CR500™ SINGLE-DOSE GEL Medical Device in Patients With Knee Osteoarthritis (KOA)
Evaluate the long-term efficacy of the CR500™ therapy in patients with knee OA.
- Trial name
- NCT07322770
- Testing
- CR 500™ SINGLE-DOSE GEL
- Where
- Italy
- Volunteers
- 35 people
- Sponsor
- Contrad Swiss SA
Osteoarthritis of the Knee
Axial Alignment in Patients Operated Using the Visionaire Patient Matched Cutting Blocks
Title: PATIENT-MATCHED INSTRUMENTATION VS. STANDARD INSTRUMENTATION: A RANDOMIZED CLINICAL TRIAL COMPARING POSTOPERATIVE AXIAL ALIGNMENT and COMPONENT POSITION Short Title: Visionaire Alignment Methodology: Monocentric, Single…
- Trial name
- Visionaire (NCT01224522)
- Testing
- Visionaire, Standard surgical technique
- Where
- United Kingdom
- Volunteers
- 70 people
- Sponsor
- Smith & Nephew Orthopaedics AG
Hip and Knee Osteoarthritis
Outcomes Data of Bone Marrow Stem Cells to Treat Hip and Knee Osteoarthritis
The purpose of this study is to determine if Bone Marrow Concentrate may be successful in the treatment of osteoarthritis. Bone Marrow Concentrate is known to contain a community of cells that has been shown to have…
- Trial name
- NCT01601951
- Testing
- Procedural, Bone Marrow concentrate injection
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Regenerative Pain Center, Illinois
Knee Osteoarthritis
Fu's Subcutaneous Needling Treatment for Knee Osteoarthritis
The population affected by degenerative knee arthritis is very large. The investigator performed Fu's subcutaneous needling (FSN).
- Trial name
- NCT04356651
- Testing
- Fu's subcutaneous needling(FSN), Transcutaneous Electric Nerve Stimulation
- Where
- Taiwan
- Volunteers
- 32 people
- Sponsor
- China Medical University Hospital
Osteoarthritis, Degenerative Joint Disease
Adding Value in Knee Arthroplasty Post-total Knee Replacement (TKR) Care Navigator Trial
The objectives of this research are to: Conduct a proof of concept randomized controlled trial with up to 300 patients undergoing primary total knee replacement (TKA) at Brigham and Women's Hospital (BWH).
- Trial name
- AViKA (NCT01540851)
- Testing
- Care Navigator, Standard Post-Operative TKA Care
- Where
- United States
- Volunteers
- 308 people
- Sponsor
- Brigham and Women's Hospital
Osteoarthritis, Knee
Hip Joint Mobilizations and Strength Training in Patients With Knee OA Osteoarthritis
Knee osteoarthritis has been ranked 11th highest contributor to non-fatal burdens in the world. Many research studies have discussed the relationship of hip muscle with knee joint stating that impaired hip strength can be a…
- Trial name
- NCT04769531
- Testing
- Hip Joint Mobilizations, Hip joint Muscle strength training, knee strengthening and flexibility exercises
- Where
- Pakistan
- Volunteers
- 66 people
- Sponsor
- Dow University of Health Sciences
Knee Osteoarthritis
Additional Effects of Steroid and Dextrose to Hyaluronic Acid on Knee Osteoarthritis
Using double-blind, randomized controlled design to compare the immediate, short-term and intermediate-term additional therapeutic effects of ultrasound-guided corticosteroid injection and dextrose injection of hyaluronic acid…
- Trial name
- NCT04165902
- Testing
- compare the effects of steroid plus hyaluronic acid and destrose plus hyaluronic acid on knee osteroarthritis
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Taipei Medical University
Blood Flow Restriction
Vascular Occlusion for Optimizing Functional Improvement in Patients With Knee Osteoarthritis
Recent research in strength training physiology revealed that implementation of occlusion garments around the proximal aspect of the lower limbs in combination with low load strength training causes a reduced blood flow and thus…
- Trial name
- VOFIKO (NCT04996680)
- Testing
- Blood Flow Restriction (by using smart-cuff pro devices, acting as pressurized tourniquet) combined low load strengh training, Standardised low load strength training
- Where
- Belgium
- Volunteers
- 120 people
- Sponsor
- University Hospital, Ghent
Knee Osteoarthritis
Benefits of Spa Therapy in Saint-Lary Soulan for Knee Osteoarthritis
The hypothesis is that the use of spa therapy in Saint-Lary Soulan for knee osteoarthritis treatment would have a therapeutic effect on this pathology.
- Trial name
- LARYTHERM (NCT05790824)
- Testing
- Spa therapy
- Where
- France
- Volunteers
- 88 people
- Sponsor
- University of Bordeaux
Knee Osteoarthritis (Knee OA)
Exercise-induced Irisin in Individuals With Knee Osteoarthritis.
The goal of this prospective randomised controled study is to investigate the effect of 8-weeks brisk walking exercise on irisin levels, physical and psychosocial parameters in individuals with knee osteoarthritis, and the…
- Trial name
- Osteoarthritis (NCT06758388)
- Testing
- home exercise program, home exercise program + brisk walking exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people
- Sponsor
- Ümmahani Kuş
Osteoarthritis
Qigong Therapy for Individuals With Knee Osteoarthritis
The purpose of this study is to evaluate the effectiveness of Qigong therapy, an ancient Chinese practice, for pain relief and symptom improvement in people with knee osteoarthritis (OA).
- Trial name
- NCT00104156
- Testing
- External Qigong therapy
- Where
- 2 sites in United States
- Volunteers
- 100 people
- Sponsor
- National Center for Complementary and Integrative Health (NCCIH)
Knee Osteoarthritis
A Trial to Evaluate the Safety, Tolerability, and Efficacy of NCR100 Injection in the Treatment of Subjects With KOA
This clinical study is to investigate the safety and efficacy of NCR100 injection in subjects with knee osteoarthritis (KOA). It is a dose-escalating, open label study in adult KOA subjects.
- Trial name
- NCR100 (NCT06049342)
- Testing
- NCR100 injection
- Volunteers
- 12 people
- Sponsor
- Nuwacell Biotechnologies Co., Ltd.
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