Clinical trials: Knee Arthritis Disease
Knee Osteoarthritis, Hip Osteoarthritis
Quality of Care for Knee and Hip Osteoarthritis in Elderly Patients
Introduction: Hip and knee osteoarthritis (OA) was ranked in 2010 as the eleventh highest contributor to global disability. In France in 2014, non-spinal OA was the leading self-reported cause of morbidity among adults over…
- Conditions
- Knee Osteoarthritis, Hip Osteoarthritis, Quality of Healthcare, Elderly
- Trial name
- QSAMISA (NCT04170218)
- Where
- France
- Volunteers
- 405 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Knee Osteoarthritis
EMBOLIZATION IN PATIENTS WITH TOTAL KNEE PROSTHESIS WITH PAIN RESISTANT TO MEDICAL TREATMENT
The objective of this study is to evaluate at 3 months in a prospective study, the effectiveness of arterial embolization of neo-vessels in patients with a painful total knee prosthesis despite a well-conducted medical treatment
- Trial name
- NCT04566315
- Testing
- Arteriography knee arteriography
- Where
- France
- Volunteers
- 10 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Knee Osteoarthritis
Ketorolac Versus Triamcinolone Knee Injections for Osteoarthritis
Osteoarthritis is a disabling disease of the joint spaces and has a high impact on society due to the amount of people who are affected by the disease. Nonoperative management is a mainstay of therapy in most patients.
- Trial name
- NCT02295189
- Testing
- Ketorolac Tromethamine, Triamcinolone Acetonide
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- San Antonio Military Medical Center
Osteo Arthritis Knee
Effects of Retro-walking in Patients With Knee OA
Osteoarthritis is degenerative joint disease that cause deterioration of the articular cartilage and neighboring tissue and lead to osteophyte formation, weakening of surrounding muscles, ligamentous laxity and inflammation of…
- Trial name
- NCT06130774
- Testing
- Retro walking and conventional, conventional therapy
- Where
- Pakistan
- Volunteers
- 28 people
- Sponsor
- Riphah International University
Knee Osteoarthritis
Follow-up Study for Participants Jointstem Clinical Trial
This study is a long term follow-up study to investigate the safety of autologous transplantation of Adipose Tissue derived Mesenchymal stem cells (MSCs) in patient with Knee Osteoarthritis.
- Trial name
- NCT03509025
- Testing
- Jointstem
- Where
- 2 sites in South Korea
- Volunteers
- 11 people
- Sponsor
- R-Bio
Knee Osteoarthritis
Vibratory Stimuli, A Novel Rehabilitation Method for Preventing Post - Traumatic Knee Osteoarthritis
This study will evaluate the acute effects of vibration (whole body vibration and local muscle vibration) on quadriceps function, knee joint proprioception, and gait biomechanics linked to osteoarthritis development in…
- Trial name
- NCT02605876
- Testing
- Whole body vibration, Local muscle vibration
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- University of North Carolina, Chapel Hill
Osteoarthritis
Comparison of Stability and Outcomes in Single-radius Femoral Component for Total Knee Arthroplasty
This is a comparison of the functional results and Varus-Valgus Stability in Single-radius versus Multi-radius Femoral Component for Total Knee Arthroplasty.
- Trial name
- NCT01379755
- Where
- South Korea
- Volunteers
- 213 people, healthy volunteers welcome
- Sponsor
- Chonnam National University Hospital
Osteoarthritis,Knee, Osteoarthritis Knees Both
Coach2Move: Physical Therapy to Improve Physical Activity in Individuals With Chronic MSK Conditions
Chronic musculoskeletal conditions (chronic low back pain, knee osteoarthritis, hip osteoarthritis) are the most common causes of long-term disability resulting in a loss of quality-of life for affected individuals and high costs…
- Conditions
- Osteoarthritis,Knee, Osteoarthritis Knees Both, Osteoarthritis Hip, Low Back Pain
- Trial name
- Coach2Move (NCT07806318)
- Testing
- motivational enhancement and planning
- Where
- United States
- Volunteers
- 94 people
- Sponsor
- University of Utah
Pain, Osteoarthritis, Knee
A Comparison of the Analgesic Efficacy and Safety of Once Daily Tramadol OAD Tablets to Twice Daily Tramadol BID for the Treatment of Osteoarthritis of the Knee (Extension Protocol) and Open Label Safety Follow-Up
The purpose of this study is to evaluate the long-term safety (up to one year) of Tramadol Once-A-Day (OAD) tablets at the highest doses: 200-400 mg
- Trial name
- NCT00912015
- Testing
- Tramadol OAD, Tramadol OAD 100mg
- Volunteers
- 238 people
- Sponsor
- Labopharm Inc.
Osteoarthritis, Knee
In Vivo Three-Dimensional Determination of Osteoarthritis Brace Effectiveness
In vivo knee kinematics will be assessed for 20 subjects that have been clinically diagnosed with substantial unicompartmental osteoarthritis (OA) by one of the surgeons of Colorado Joint Replacement; this is the location from…
- Trial name
- NCT04111276
- Testing
- Breg Osteoarthritis Brace gait fluoroscopy, Gait fluoroscopy without brace, JointVue ultrasound
- Where
- 3 sites in United States
- Volunteers
- 23 people
- Sponsor
- The University of Tennessee, Knoxville
Knee Acute and Chronic Pain
Acute Effect of Inferential Therapy (IFT) and Short Wave Diathermy (SWD) on Balance in Subjects With Knee Pain
Background: The Y balance test is a dynamic test that requires strength, flexibility, and proprioception. It is a measure of dynamic balance that provides a significant challenge to athletes and physically active individuals.
- Trial name
- IFT & SWD (NCT04148768)
- Testing
- Inferential therapy, short wave diathermy
- Where
- Saudi Arabia
- Volunteers
- 30 people
- Sponsor
- King Khalid University
Osteoarthritis, Knee
Probiotic Supplements in Osteoarthritis
The current study aims to evaluate the effectiveness of adding probiotics to the standard of care in improving OA patient-related outcomes such as pain, stiffness, and physical activity.
- Trial name
- NCT07364578
- Testing
- Probiotic Formula, Control
- Where
- Egypt
- Volunteers
- 146 people
- Sponsor
- Beni-Suef University
Osteoarthritis of Knee
Pain Relief for OsteoArthritis Through Combined Treatment (PROACT)
This mechanistic clinical trial proposes to test whether a five-day course of mindfulness meditation training (MMT) and tDCS, and their combination, can enhance pain modulatory balance and pain-related brain function, reduce…
- Trial name
- PROACT (NCT03884374)
- Testing
- Focused Breathing and Attention Training (BAT), Standard Breathing and Attention Training (BAT), Transcranial Direct Current Stimulation (tDCS)
- Where
- 2 sites in United States
- Volunteers
- 317 people
- Sponsor
- University of Florida
Osteoarthritis
DSJ-2016-07 ATTUNE® Cementless CR RP Japan
The primary objective is to investigate the change from pre-operative baseline to two year postoperative functional performance improvement for the ATTUNE® primary, cementless TKA RP system as measured with the KOOS questionnaire…
- Trial name
- NCT03193034
- Testing
- Cementless Total Knee Arthroplasty
- Where
- 4 sites in Japan
- Volunteers
- 81 people
- Sponsor
- DePuy Orthopaedics
Total Knee Arthroplasty, Total Knee Replacement
Comparing Temperature in Burr vs Saw Cutting for Knee Arthroplasty
We will assess the temperatures achieved during bone cutting in total knee replacements, comparing burr and saw techniques. Our study involves recruiting 20 patients from East Suffolk and North Essex NHS Foundation Trust…
- Trial name
- NCT07010809
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- East Suffolk and North Essex NHS Foundation Trust
Knee Osteoarthritis
Influence of Perception of Patients Suffering of Knee Osteoarthritis Regarding Effectiveness of Intra-articular Injection
Introduction; reception must be understood as the offered attention within the relationship between a healthcare worker and the patient, including attitudes of inclusion, hearing, valorization of complains and identification of…
- Trial name
- NCT02835521
- Testing
- Reception, Joint injection with triamcinolone hexacetonide
- Volunteers
- 100 people
- Sponsor
- Federal University of São Paulo
Knee Osteoarthritis
Efficacy of Biodex Balance Training Versus Whole Body Vibration Training in Patients With Knee Osteoarthritis
This study will be conducted to answer the research question: Are there differences between the effect of Biodex balance training and Whole-body vibration training on Knee osteoarthritis?
- Trial name
- NCT06563258
- Testing
- Biodex Balance Training, A vibration device, traditional exercises
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cairo University
Osteoarthritis, Total Knee Arthroplasty
Use of Cold and Compression Therapy With Total Knee Replacement Patients
The purpose of the study is to evaluate the effectiveness of a device that delivers cold and intermittent compression as compared to ice and compressive wraps on patients who have undergone knee replacement.
- Trial name
- NCT00712816
- Testing
- Game Ready Injury Treatment System (CoolSystems Inc.), Ice with compressive bandages
- Where
- 11 sites in United States, Australia
- Volunteers
- 224 people
- Sponsor
- CoolSystems, Inc.
Osteoarthritis
Total Knee Arthroplasty: Relation Between Patient Satisfaction and Implant Geometry
A RCT (randomized controlled trial) comparing 3 different TKA (total knee arthroplasty) implant designs and investigating the relation between patient satisfaction and the implant geometry.
- Trial name
- NCT02663804
- Testing
- Total Knee Arthroplasty
- Where
- Belgium
- Volunteers
- 380 people
- Sponsor
- University Hospital, Ghent
Osteoarthritis Knee
Comparison of an Old Versus a New Total Knee Replacement
A randomized controlled clinical and RSA study, comparing 2 knee implants: 1. NexGen CR cemented total knee arthroplasty 2. Persona CR cemented total knee arthroplasty 3 hospitals will participate in the study: Helse Bergen HF…
- Trial name
- NCT03548792
- Testing
- RSA radiostereometric analysis, Clinical comparison
- Where
- Norway
- Volunteers
- 185 people, healthy volunteers welcome
- Sponsor
- Helse-Bergen HF