Clinical trials: Knee Arthritis Disease
Osteoarthritis, Knee
MR Imaging of Knee Osteoarthritis and Acute Knee Injuries
The purpose of this study is to use better magnetic resonance imaging (MRI) techniques to examine the knee and the bony and soft tissue changes so as to better predict the progression of osteoarthritis and acute knee injuries.
- Trial name
- NCT00504114
- Testing
- ACL Reconstruction Surgery, Cartilage Resurfacing Surgery, Total Knee Replacement
- Where
- United States
- Volunteers
- 139 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Osteoarthritis (OA) of the Hip, Osteoarthritis (OA) of the Knee
Sleep and Pain in Osteoarthritis
People with osteoarthritis and painful joints often report poor sleep, but poor sleep can also increase pain. There have been very few studies of sleep in osteoarthritis using physical measuring devices, but in other painful…
- Trial name
- NCT07821047
- Volunteers
- 73 people
- Sponsor
- University of Reading
Total Knee Arthroplasty, Osteoarthritis
Computer Assisted Total Knee Replacement
The purpose of this study is to determine whether intraoperative computer-assisted navigation improves prosthetic implant positioning as compared to conventional intraoperatve instrumentation in Total Knee Arthroplasty (TKA).
- Trial name
- NCT00279838
- Testing
- Computer Assisted Navigation Knee Replacement
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Mayo Clinic
Knee Osteoarthritis
Comparative Effectiveness of Otago and Neuromuscular Exercise Programs in Knee Osteoarthritis
This randomized controlled trial aims to compare the effects of the Otago Exercise Program (OEP) and neuromuscular exercises on pain, functional status, postural control, and balance in patients with knee osteoarthritis (KOA).
- Trial name
- NCT07078526
- Testing
- Otago Exercise Program, Neuromuscular Exercise
- Where
- Pakistan
- Volunteers
- 58 people
- Sponsor
- Riphah International University
Osteoarthritis, Knee
How Does Platelet Dose Impact Clinical Outcomes After PRP Treatment?
The purpose of this study is to determine which platelet rich plasma (PRP) injection dosage provides the most improvement in a patient's knee pain level at 26 weeks post-injection.
- Trial name
- NCT05330689
- Testing
- PRP injection dose (<5 billion platelets), PRP injection dose (between 5 and <10 billion platelets), PRP injection dose (between 10 and <20 billion platelets)
- Where
- United States
- Sponsor
- Vanderbilt University Medical Center
Genu Varum, Knee Osteoarthritis
Effect of RO On GB During TKR Severe Varus Deformity
Effect Of Reduction Osteotomy On Gap Balancing During Total Knee Replacement For Severe Varus Deformity
- Trial name
- NCT03065738
- Testing
- tibial reduction osteotomy in total knee replacement
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Assiut University
Gonarthrosis, Knee Osteoarthritis
Evaluation of Intra-articular Injection of Autologous Protein Solution ("APS(TM)") for the Treatment of Osteoarthritis (OA)
This prospective single-center study will evaluate the safety and tolerability of a single dose of "APS(TM)" treated patients with OA of the knee who have failed conservative OA therapy.
- Conditions
- Gonarthrosis, Knee Osteoarthritis, Osteoarthritis
- Trial name
- NCT01773226
- Testing
- Autologous Protein Solution "APS(TM)"
- Where
- Netherlands
- Volunteers
- 11 people
- Sponsor
- Zimmer Biomet
Osteoarthritis, Knee
Intra and Inter Reliability of 30 Seconds Chair Stand Test as Self-test for Patients With Knee Osteoarthritis.
Background: It is estimated that 14% of the Swedish population have knee osteoarthritis. Common osteoarthritis symptoms are pain, stiffness and impaired physical function.
- Trial name
- NCT03855813
- Testing
- Intra rater reliability, Inter rater reliability
- Where
- 3 sites in Sweden
- Volunteers
- 129 people
- Sponsor
- Vastra Gotaland Region
Knee Osteoarthritis
Quantitative MRI For Detection and Tracking of Knee Osteoarthritis
The goal of this observational study is to develop whole-joint quantitative MRI techniques that aid in the detection and tracking of osteoarthritis disease progression at 3T and 7T MRI scanners. The research objectives are: 1.
- Trial name
- NCT06063304
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Knee Pain
A Reliability and Validity Study of Urdu Version of Knee Outcome Survey-Activities of Daily Living Scale
The purpose of this study is to translate Knee Outcome Survey-Activities of Daily Living Scale into Urdu language and to check the reliability and validity of the Knee Outcome Survey-Activities of Daily Living Scale in Urdu…
- Trial name
- NCT05221047
- Where
- Pakistan
- Volunteers
- 150 people
- Sponsor
- Riphah International University
Knee Osteoarthritis
Effectiveness and Safety of Embosphere Microspheres for Embolization of the Geniculate Artery for the Treatment of Pain With Known Moderate to Severe Knee Osteoarthritis
The purpose of this research study is to evaluate the effectiveness and safety of a permanent embolic (Embosphere Microspheres) for embolization of the geniculate artery for the treatment of moderate to severe knee osteoarthritis.
- Trial name
- NCT05112926
- Testing
- Embosphere Microspheres
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- University of Miami
Knee Osteoarthritis
Comparison of Mini Squat and Endurance Training in Improving Quality of Life in Knee Osteoarthritis
Interventional type of study in which one group of participants will be given mini squats training and other endurance training to improve the quality of life of knee osteoarthritis patients.
- Trial name
- NCT06056076
- Testing
- Mini Squats Training, Endurance Training
- Where
- Pakistan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Neuro Counsel Hospital, Pakistan
Obesity, Weight Loss
Impact of the Excess Weight Loss on Mineralization Patterns of the Knee After Bariatric Operations
Evaluation of the subchondral mineralization plate after excess weight loss in patientes undergoing bariatric operation by means of CT-osteoabsorptiometry.
- Conditions
- Obesity, Weight Loss, Knee Osteoarthritis
- Trial name
- CT-OAM (NCT02404090)
- Testing
- CT-osteoarbsorptiometry
- Volunteers
- 50 people
- Sponsor
- Marko Kraljevic
Meniscus Tear, Tibial, Osteoarthritis, Knee
Arthroscopic Partial Meniscectomy Versus Exercise Therapy for Meniscal Injuries in Older Patients, a 5 Year Follow up.
Arthroscopic partial meniscectomie (APM) offers little short-term to medium-term benefit above sham surgery or non-surgical management for knee function in most patients with a symptomatic degenerative meniscus tear.
- Trial name
- NCT05068843
- Testing
- arthroscopic partial meniscectomy, Physical therapy
- Volunteers
- 321 people
- Sponsor
- Onze Lieve Vrouwe Gasthuis
Knee Osteoarthritis
Whole Body Vibration on Running Biomechanics
Whole body vibration (WBV) acutely improves quadriceps strength, and may improve long-term outcomes in individuals with anterior cruciate ligament reconstruction (ACLR).
- Trial name
- NCT02851316
- Testing
- Whole Body Vibration
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- California State University, Fullerton
Knee Osteoarthritis
Tai Chi and Physical Therapy for Knee Osteoarthritis
We will conduct a large randomized controlled trial comparing the effectiveness and cost-effectiveness of Tai Chi mind-body exercise and standard-of-care Physical Therapy for Knee Osteoarthritis.
- Trial name
- TCPT (NCT01258985)
- Testing
- Tai Chi, Physical Therapy
- Where
- United States
- Volunteers
- 204 people
- Sponsor
- Tufts Medical Center
OsteoArthritis Knee
A Comparison of 2-octyl Cyanoacrylate Skin Adhesive and Polyester Mesh for Wound Closure in Total Knee Arthroplasty, A Randomized Controlled Study
The goal of this randomized controlled study is to investigate the Efficacy of Using skin adhesive (Dermabond) and skin adhesive with polyester mesh (Dermabond Prineo )for Wound Closure in Total Knee Arthroplasty, The main…
- Trial name
- NCT06232018
- Testing
- Skin adhesive (Dermabond), skin adhesive + polyester mesh (Dermabond prineo)
- Where
- Thailand
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Pooriwat Lertsurawat
Osteoarthritis
A Study of the Efficacy and Safety of Synvisc® in Chinese Subjects With Symptomatic Osteoarthritis of the Knee(s)
Primary Objective: To evaluate the change of Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) A1 subscore (walking pain) at 26 weeks compared to the Baseline score To evaluate the safety using the incidence…
- Trial name
- NCT01586338
- Testing
- Hylan G-F 20
- Where
- China
- Volunteers
- 237 people
- Sponsor
- Sanofi
Osteoarthritis
Collaborative Lifestyle Intervention Program in Knee Osteoarthritis Patients
The Collaborative Lifestyle Intervention Program in Knee OsteoArthritis Patients (CLIP-OA) compares a novel community-based exercise and dietary weight loss program to the Arthritis Foundation's Walk with Ease intervention on…
- Trial name
- CLIP-OA (NCT02835326)
- Testing
- Exercise and Dietary Weight Loss, Walk with Ease
- Where
- United States
- Volunteers
- 227 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Knee Osteoarthritis
Internal Compartment Knee Osteoarthritis: ODRA (Orthosis Distraction and Rotation for osteoArthritis) Made-to-measure Hinged Knee Brace Versus Usual Care.
This is a biomedical study on a medical device. 120 patients will participate in this study and will be split into 2 groups: 60 patients in the "usual care" group: these patients will receive the usual care proposed by their…
- Trial name
- ERGONOMIE (NCT02765685)
- Testing
- brace ODRA (PROTEOR company), Usual care
- Where
- France
- Volunteers
- 120 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
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