Clinical trials: Knee Arthritis Osteoarthritis
Osteo Arthritis Knee
Intermittent Hypoxia-Hyperoxia Combined With Physical Therapy for Knee Osteoarthritis
This randomized controlled trial aims to evaluate the effectiveness of combining intermittent hypoxia-hyperoxia therapy (IHHT) with conventional physical therapy in improving pain, function, gait, balance, and general health…
- Trial name
- NCT06965946
- Testing
- Intermittent Hypoxia-Hyperoxia Therapy (IHHT), Conventional Physical Therapy
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Khyber Medical University Peshawar
Knee Osteoarthristis
Study NRPT Feasibility in Knee Osteoarthritis
To Evaluate Feasibility and Exploratory Clinical and Biomarker Signals of NRPT in Adults with Knee Osteoarthritis
- Trial name
- NRPT (NCT07917403)
- Testing
- NRPT
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of California, San Diego
Osteoarthritis
Bone Graft Necessity in Opening-Wedge High Tibial Osteotomy
The purpose of this study is to determine wether autologous bone graft from iliac crest enhances bone union of tibial osteotomies, in the treatment of varus knee deformity.
- Trial name
- NCT00786942
- Testing
- high tibial osteotomy, higi tibial osteotomy
- Where
- Brazil
- Volunteers
- 44 people
- Sponsor
- University of Campinas, Brazil
Osteoarthritis, Knee
Senolytic Drugs Attenuate Osteoarthritis-Related Articular Cartilage Degeneration: A Clinical Trial
Phase I/II randomized, double-blind, placebo-controlled clinical trial to test the safety and efficacy of Fisetin for treating mild to moderate osteoarthritis
- Trial name
- NCT04210986
- Testing
- Fisetin
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Steadman Philippon Research Institute
Osteoarthritis, Knee
Transdermal Delivery of Glucosamine to the Synovial Fluid of Male and Female With Knee Osteoarthritis
Glucosamine is commonly used as a treatment for Osteoarthritis (OA). While oral administration remains the most commonly used route, topical administration could offer numerous advantages such as targeted delivery to affected…
- Trial name
- NCT03743896
- Testing
- Transdermal Glucosamine Cream
- Where
- Singapore
- Volunteers
- 240 people
- Sponsor
- Lynk Biotechnologies Pte Ltd
Arthropathy of Knee, Arthritis Knee
Validation of Consumer Activity Monitors in Postoperative Total Arthroplasty Patients
Mobilization and rehabilitation are essential components of a successful functional recovery following total hip and knee arthroplasties. Currently, we have no good measure of how mobile patients are after their surgery.
- Conditions
- Arthropathy of Knee, Arthritis Knee, Arthritis, Degenerative
- Trial name
- NCT03958370
- Testing
- Fitbit
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Benaroya Research Institute
Osteoarthritis, Joint Disease
Autologous Adipose-Derived Stromal Vascular Fraction Cells for Osteoarthritis Treatment
Adipose-derived stromal vascular fraction cells (SVFs) include regenerative cell populations (hematopoietic cells, pericytes, endothelial cells and progenitors, stromal/stem cells) and thus are potentially important as new…
- Conditions
- Osteoarthritis, Joint Disease, Osteoarthritis,Knee, Arthritis, Degenerative
- Trial name
- NCT02967874
- Testing
- Intra-articular auto-SVFs injection, Hyaluronic Acid
- Where
- Russia
- Volunteers
- 27 people
- Sponsor
- Russian Academy of Medical Sciences
Gonarthrosis
Evaluation of a New Navigation System in Computer-assisted Total Knee Arthroplasty
Evaluation of a new navigation system in computer-assisted total knee arthroplasty.
- Trial name
- NaviKnee (NCT05435690)
- Testing
- Computer-assisted arthroplasty
- Where
- France
- Volunteers
- 126 people
- Sponsor
- GCS Ramsay Santé pour l'Enseignement et la Recherche
Obesity, Weight Loss
Impact of the Excess Weight Loss on Mineralization Patterns of the Knee After Bariatric Operations
Evaluation of the subchondral mineralization plate after excess weight loss in patientes undergoing bariatric operation by means of CT-osteoabsorptiometry.
- Conditions
- Obesity, Weight Loss, Knee Osteoarthritis
- Trial name
- CT-OAM (NCT02404090)
- Testing
- CT-osteoarbsorptiometry
- Volunteers
- 50 people
- Sponsor
- Marko Kraljevic
Osteoarthritis, Knee, Arthroplasty, Replacement, Knee
Total Knee Arthroplasty Guidance Systems Study
In total knee replacement operations, the surgeon uses techniques and instruments to guide the operation and ensure that all parts of the prosthesis (the artificial knee surfaces) are placed into the correct position.
- Trial name
- NCT02830997
- Testing
- Stereotactic guidance system
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Ormonde M. Mahoney, MD
Knee Osteoarthritis
Does Addition of a Functional Knee Brace Improve Rehabilitation Outcome in Subjects With Osteoarthritis of the Knee?
The purpose of this study is to investigate the effect of functional knee brace in the subjects with medial compartment knee OA.
- Trial name
- NCT02712710
- Testing
- functional knee brace
- Where
- Taiwan
- Volunteers
- 41 people
- Sponsor
- Shin Kong Wu Ho-Su Memorial Hospital
Osteoarthritis, Gonarthrosis
Photobiomodulation Therapy to Reduce Pain and Inflammation in Patients With Gonarthrosis
Osteoarthritis (OA) is one of the main causes of chronic pain and physical disability, which directly impacts the quality of life of patients.
- Trial name
- NCT05975957
- Testing
- Photomodulation Therapy with the Light-Aid system, Control
- Where
- Brazil
- Volunteers
- 238 people
- Sponsor
- D'Or Institute for Research and Education
Osteoarthritis
Proprioception of the Knee Post MIS TKA and MIS-QS TKA
If the proprioception of the affected knee post total knee arthroplasty (TKA) can recover earlier, it will accelerate the regaining of motion control ability and motion control accuracy of the TKA patients.
- Trial name
- NCT02160977
- Testing
- total knee arthroplasty
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Jia-kuo yu
Knee Osteoarthritis
Bone Marrow Versus Adipose Tissue as a Cell Source for Infiltrative Treatment of Knee Osteoarthritis
The MAST-GR study is a randomized controlled interventional trial with parallel treatment arms and 1:1 allocation The primary objective of the study is to compare the safety and efficacy of a single intra-articular infiltration…
- Trial name
- NCT06040957
- Testing
- Bone marrow aspirate concentrate injection, intra-articular injection of Minimally manipulated adipose tissue
- Where
- Italy
- Volunteers
- 204 people
- Sponsor
- Istituto Ortopedico Rizzoli
Osteoarthritis
Study to Assess the Efficacy and Safety of Reflex Plus™ in Osteoarthritis
Reflex plus™ is a unique blend of Collagen Hydrolysate with Rosehip extract. The blend contains individual ingredients which have been widely studied for its effectiveness in osteoarthritis(OA).
- Trial name
- NCT02655939
- Testing
- Reflex Plus
- Where
- India
- Volunteers
- 258 people
- Sponsor
- Vedic Lifesciences Pvt. Ltd.
Knee Osteoarthritis
Balneotherapy With Acquabios Thermal Water in Knee Osteoarthritis
The aim of the study is the evaluation of the effect of balneotherapy with Acquabios bicarbonate-alkaline-sodium thermal water in ameliorating some signs and symptoms of knee osteoarthritis in human subjects suffering from this…
- Trial name
- NCT05352477
- Testing
- Balneotherapy with thermal water, Balneotherapy with tap water
- Volunteers
- 88 people
- Sponsor
- University of Roma La Sapienza
Osteoarthritis, Knee
Clinical Outcomes of MP Persona vs. Persona Knee-PS
Knee osteoarthritis (OA) is a highly prevalent condition that results in substantial pain and loss of function. The end stage treatment for knee OA is total knee arthroplasty (TKA), a common and safe procedure typically performed…
- Trial name
- MP-Persona (NCT03681977)
- Testing
- Zimmer MP Persona, Zimmer Persona Knee-PS
- Where
- 3 sites in Canada
- Volunteers
- 162 people, healthy volunteers welcome
- Sponsor
- Lady Davis Institute
Knee Osteoarthritis
A Multicenter, Open-Label, Single-Arm Extension Study to Evaluate the Safety and Efficacy of FURESTEM-OA-Kit Inj. in Knee Osteoarthritis Patients Who Received Placebo in the K0701 Phase 2a Trial
A Multicenter, Open-Label, Single-Arm Extension Study to Evaluate the Safety and Efficacy of FURESTEM-OA-Kit Inj. in Knee Osteoarthritis Patients Who Received Placebo in the K0701 Phase 2a Trial
- Trial name
- NCT07754175
- Where
- 2 sites in South Korea
- Volunteers
- 36 people
- Sponsor
- Kang Stem Biotech Co., Ltd.
Synovitis, Osteoarthritis
Effect of Chondroitin Sulphate on Synovial Inflammation in Patients With Osteoarthritis of the Knee
The purpose of this study is to determine the effect of a chondroitin sulphate conventional treatment on the degree of severity of synovitis, as measured by magnetic resonance in patients with knee OA with clinical synovitis.
- Conditions
- Synovitis, Osteoarthritis, Joint Diseases, Muskuloskeletal Diseases
- Trial name
- NCT00604539
- Testing
- Chondroitin sulphate (Condrosan)
- Where
- 4 sites in Canada
- Volunteers
- 70 people
- Sponsor
- Bioiberica
Osteoarthritis, Knee
Extracorporeal Shock Wave Therapy in Osteoarthritis
The present study has examined the effectiveness of extracorporeal shock wave therapy along with conventional physical therapy on functional ability in grade IV knee osteoarthritis.
- Trial name
- NCT06181955
- Testing
- Extracorporeal Shock Wave Therapy, conventional physical therapy
- Where
- Saudi Arabia
- Volunteers
- 30 people
- Sponsor
- King Saud University
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