Clinical trials: Knee Arthropathy
Osteoarthritis, Knee, Osteoarthritis, Hip
Improving Resilience and Longevity for Workers Through Exercise
The purpose of this study is to examine the impact of an OA-specific aerobic and strengthening exercise program, delivered within the workplace, on mobility, pain, physical capacity, and resilience among workers with knee or hip…
- Trial name
- NCT03050320
- Testing
- Exercise, No Exercise
- Where
- Canada
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- McMaster University
Knee Osteoarthritis
Geniculate Artery Embolization for the Treatment of Knee Osteoarthritis
Osteoarthritis (OA) is a highly prevalent degenerative joint disease that contributes to chronic pain and disability in approximately 10% of people over the age of 55.
- Trial name
- NCT05386797
- Testing
- Geniculate Artery Embolization
- Where
- Canada
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Osteoarthritis, Knee, Osteoarthritis, Hip
Study Of "Continuous Use" Of Celecoxib Vs. "Usual or Intermittent Use"
To determine whether "continuous use" of celecoxib over a 6-month period is more efficacious than "usual or intermittent use" in preventing spontaneous osteoarthritis flares of the knee and hip.
- Trial name
- NCT00139776
- Testing
- Celecoxib
- Where
- 124 sites in United States, Belgium and 6 more
- Volunteers
- 875 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Patellar Dislocation
Comparison of Two Graft Choices in Mediale Patellofemoral Ligament Reconstruction (MPFL)
The purpose of this study is to elucidate surgical techniques for reconstructing MPFL in the treatment of chronic patella instability.
- Trial name
- NCT05706363
- Testing
- Quadriceps graft
- Where
- Denmark
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Aarhus University Hospital
Osteoarthritis, Knee
Effects of Including a Chronic Pain Neuroscience Education Program for Individuals With Knee OA
Research participants diagnosed with knee osteoarthritis will be randomized through a draw using sealed opaque envelopes indicating two groups: 1. therapeutic exercises, 2.
- Trial name
- NCT06187038
- Testing
- Therapeutic exercises, Therapeutic exercises + pain neuroscience education program
- Where
- Brazil
- Volunteers
- 92 people
- Sponsor
- University of Nove de Julho
Total Knee Arthroplasty, Total Knee Replacement
ALknee Follow-up Study of the Cementless ATTUNE Rotating Platform and the Cementless LCS Rotating Platform Knee System
The cementless ATTUNETM Rotating Platform Knee system was compared in a single-blind, randomized RSA trial to its predecessor, the LCS rotating platform Knee System.
- Conditions
- Total Knee Arthroplasty, Total Knee Replacement, Knee Osteoarthritis
- Trial name
- NCT05623215
- Testing
- Radiographs of the knee for radiostereometric analysis (RSA)
- Where
- Netherlands
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Spaarne Gasthuis
Knee Osteoarthritis
Telerehabilitation of Patients After Knee Surgery
This project is aimed to investigate the feasibility of employing communication and sensor technologies for the patient after a knee operation.
- Trial name
- NCT03731208
- Testing
- Telerehabilitation
- Where
- 2 sites in Denmark
- Volunteers
- 12 people
- Sponsor
- Aalborg University
Osteoarthritis, Knee
Effects of Corrective Exercise Training for Improving Neuropathic Pain and Function in Knee Osteoarthritis
Patients with neuropathic pain had longer duration of symptoms increased severity of pain, functional limitation and disability as compare to the patient with general knee osteoarthritis.
- Trial name
- NCT04995250
- Testing
- corrective exercise training for knee
- Where
- Pakistan
- Volunteers
- 16 people
- Sponsor
- Riphah International University
Knee Osteoarthritis
Comparison of Single Intra-articular Injection of Hyruan-One With Hylan G-F 20 in Knee Osteoarthritis
We compare the efficacy of intra-articular injection of Hyruan-One with Hylan G-F 20 and placebo (NSS) controlled in a double-blind RCT.
- Trial name
- NCT03484091
- Testing
- Hyruan-One, Hylan G-F 20, Normal saline
- Where
- Thailand
- Volunteers
- 276 people
- Sponsor
- Thammasat University
Osteoarthritis, Pain
Study to Assess MEDI -578 in Patients With Osteoarthritis (OA) of the Knee
The purpose of this study is to evaluate the safety and tolerability of a single intravenous dose of MEDI-578, a monoclonal antibody, in patients with osteoarthritis of the knee.
- Trial name
- NCT01072591
- Testing
- MEDI-578
- Where
- United Kingdom
- Volunteers
- 108 people
- Sponsor
- AstraZeneca
Osteoarthritis, Knee
PRP-HA Versus HA in Knee Osteoarthritis
Osteoarthritis (OA) is a prevalent chronic condition which most commonly affects the knee. The pathogenesis of OA involves initial mechanical stress resulting in cartilage lesions, leading to inflammatory processes causing joint…
- Trial name
- NCT05076526
- Testing
- Hyaluronic acid (Synolis VA), Cellular Matrix platelet-rich-plasma with hyaluronic acid (CM PRP-HA)
- Volunteers
- 132 people
- Sponsor
- Singapore General Hospital
Mild Knee Osteoarthritis
Tregocel® as a Dietary Supplement in Mild Knee Osteoarthritis
This study is an assessment of the overall performance of participants with symptomatic mild knee OA taking Tregocel® as a dietary supplement in addition to standard of care treatment.
- Trial name
- NCT03636035
- Testing
- Tregocel®
- Where
- Poland
- Volunteers
- 150 people
- Sponsor
- Max Biocare Pty. Ltd.
Hip Arthropathy, Knee Arthropathy
Effect of Vitamin D Status and Repletion on Postoperative Total Joint Arthroplasty Complications
Vitamin D status has been shown to have an effect on post-operative outcomes in total joint arthroplasty. The goal of this study is to determine if pre-operative supplementation and correction of Vitamin D deficiency can reduce…
- Conditions
- Hip Arthropathy, Knee Arthropathy, Vitamin D Deficiency
- Trial name
- NCT04229368
- Testing
- Vitamin D3
- Where
- United States
- Volunteers
- 900 people
- Sponsor
- Brigham and Women's Hospital
Knee Osteoarthritis
Safety and Effectiveness Study of a Non-Crosslinked HA Alkylamide HYADD(TM) 4 Hydrogel for Osteoarthritis of the Knee
The purpose of this study is to determine whether intra-articular hyaluronic acid provides symptomatic relief of osteoarthritis of the knee.
- Trial name
- NCT02187549
- Testing
- HYMOVIS
- Where
- 21 sites in United States
- Volunteers
- 332 people
- Sponsor
- Fidia Farmaceutici s.p.a.
Osteo Arthritis Knee
Efficacy of Duloxetine Compared to NSIADs in Osteoarthritis of Knee
Osteoarthritis (OA) is the most common degenerative joint disease, affecting more than 25% of the population . Knee OA is an insidious disease related to structural changes in the joint over many years.
- Trial name
- Duloxetine (NCT05486026)
- Testing
- Duloxetine 30 MG, Nonsteroidal Antiinflammatory Drug
- Where
- Iraq
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Hawler Medical University
Knee Osteoarthritis
Investigation of the Effect of Proximal and Distal Adductor Canal Block in Knee Replacement Surgery
to investigate the effect of adductor canal block applied with two different approaches in the treatment of pain after TKA surgery on pain control and functional mobility.
- Trial name
- NCT06188806
- Testing
- ADDUKTOR CANAL BLOCK, CONTROL GROUP
- Where
- Turkey (Türkiye)
- Volunteers
- 78 people
- Sponsor
- Umraniye Education and Research Hospital
Osteoarthritis, Knee
A Long-Term Safety Study of IDEA-033 in Comparison to Oral Naproxen for the Treatment of Osteoarthritis of the Knee
The purpose of this study is to evaluate the long-term safety of IDEA-033 (an anti-inflammatory pain-relieving drug applied to the skin) in comparison to naproxen (an anti-inflammatory pain-relieving drug taken by mouth) for the…
- Trial name
- NCT00265304
- Testing
- Ketoprofen
- Where
- 93 sites in United States
- Volunteers
- 550 people
- Sponsor
- IDEA AG
Osteoarthritis, Knee, Osteonecrosis
Focused Registry on the Conservative Treatment of Osteoarthritis of the Knee
The primary objective of this registry is to assess the functional outcome measured with the Knee Injury and Osteoarthritis Outcome Score (KOOS) for patients with medial unicompartmental osteoarthritis and osteonecrosis of the…
- Trial name
- NCT02077647
- Where
- 4 sites in Japan
- Volunteers
- 20 people
- Sponsor
- AO Clinical Investigation and Publishing Documentation
Osteoarthritis
A Study of the Efficacy and Safety of Synvisc® in Chinese Subjects With Symptomatic Osteoarthritis of the Knee(s)
Primary Objective: To evaluate the change of Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) A1 subscore (walking pain) at 26 weeks compared to the Baseline score To evaluate the safety using the incidence…
- Trial name
- NCT01586338
- Testing
- Hylan G-F 20
- Where
- China
- Volunteers
- 237 people
- Sponsor
- Sanofi
Osteoarthritis of the Knee
Polycan in Combination With Glucosamine for Treatment of Knee Osteoarthritis
The objectives of this study is to examine the Safety and Efficacy of black yeast beta-glucan produced from Aureobusidium pulluluns SM-2001 (Polycan), in combination with glucosamine in reducing knee osteoarthritis (OA) associated…
- Trial name
- NCT03717714
- Testing
- Glucosamine 1500 mg, Polycan 50mg + Glucosamine 750 mg, Polycan 50mg + Glucosamine 1500 mg
- Where
- Vietnam
- Volunteers
- 90 people
- Sponsor
- Vietstar Biomedical Research