Clinical trials: Knee Arthroplasty
Satisfaction, Patient
The Outcomes of Subject After Total Knee Arthroplasty
Total Knee Arthroplasty (TKA) is a standard of intervention for severe knee osteoarthritis, also been proven with benefits in improving pain, mobility, and quality of life. However, the outcomes after TKA is controversial.
- Trial name
- NCT05810090
- Testing
- Total knee arthroplasty
- Where
- Taiwan
- Volunteers
- 631 people
- Sponsor
- Changhua Christian Hospital
Total Knee Replacement, Primary Knee Replacement
Comparison of Pivotal Medial Polyethylene Versus Ultra-congruent in Total Knee Arthroplasty
The aim of this study is to compare the forgotten joint score for the medial pivot polyethylene and ultra-congruent polyethylene which are used in total prosthetic replacement of the knee
- Conditions
- Total Knee Replacement, Primary Knee Replacement, Gonarthrosis
- Trial name
- MEPCAT (NCT06676189)
- Testing
- total knee arthroplasty with medial pivot polyethylene, total knee arthroplasty with ultra-congruent polyethylene
- Where
- France
- Volunteers
- 90 people
- Sponsor
- University Hospital, Clermont-Ferrand
Replacement, Knee
The Effect of Mobile-based Education and Exercise Program Given to Patients With Total Knee Replacement Surgery
Total knee replacement (TDP) surgery is recognized as an effective surgical option for patients who develop moderate to severe osteoarthritis of the knee.
- Trial name
- NCT05187065
- Testing
- The mobile-based education and exercise program
- Where
- Turkey (Türkiye)
- Volunteers
- 108 people
- Sponsor
- Alkay Kara
Liposomal Bupivacaine, Postoperative Recovery
A Analgesic Study of Adductor Canal &IPACK Block with Liposomal Bupivacaine in Knee Arthroplasty
To study the effectiveness of ACB and iPACK block with liposomal bupivacaine for postoperative analgesia in patients undergoing knee arthroplasty
- Conditions
- Liposomal Bupivacaine, Postoperative Recovery, Unilateral Knee Arthroplasty
- Trial name
- NCT06145165
- Testing
- Nerve block with ropivacaine and intravenous analgesia, Nerve block with liposomal bupivacaine and intravenous analgesia, Intravenous analgesia
- Where
- China
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Nanjing First Hospital, Nanjing Medical University
Wound Closure
Symmetric on Total Knee Arthroplasty (TKA)
A post-marketing prospective, multicenter, randomized controlled study to evaluate the wound closure efficiency of STRATAFIX™ Symmetric PDS™ Plus Knotless Tissue Control Device (STRATAFIX Symmetric PDS Plus) compared to…
- Trial name
- SFX (NCT03305887)
- Testing
- "STRATAFIX™ Symmetric" Knotless Tissue, VICRYL® PLUS, "STRATAFIX Spiral" sutures
- Where
- 7 sites in China
- Volunteers
- 184 people
- Sponsor
- Johnson & Johnson Medical, China
Arthroplasty, Replacement, Knee
Ten Year Implant Survivorship of the ANTHEM™ PS Total Knee System
The ANTHEM™PS Total Knee System is being conducted to demonstrate non-inferiority of 10 year implant survivorship in patients undergoing total knee arthroplasty for osteoarthritis compared to reported literature
- Trial name
- ANTHEM PS (NCT03078543)
- Testing
- ANTHEM™ PS Total Knee System implant
- Where
- 8 sites in China, Italy and 3 more
- Volunteers
- 148 people
- Sponsor
- Smith & Nephew, Inc.
Osteoarthritis, Osteoarthritis, Hip
Incorporating Wearable Technology for Enhanced Rehabilitation Monitoring After Hip and Knee Replacement
This study focuses on the impact of osteoarthritis (OA), a leading cause of disability among older adults, with the hip and knee joints being particularly affected.
- Trial name
- MOVEUP-WT (NCT06157190)
- Testing
- Unsupervised monitoring
- Where
- Belgium
- Volunteers
- 1,144 people
- Sponsor
- PXL University College
Osteo Arthritis Knee
Post-op Ketamine Study
The purpose of this study is to establish the effect of sub-anesthetic dosing of ketamine with spinal anesthesia during total knee arthroplasty on post-operative pain and narcotic consumption.
- Trial name
- NCT03865550
- Testing
- Isotonic saline, Ketamine Injectable Solution
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Rothman Institute Orthopaedics
Osteoarthritis, Knee
Experimental Study of Strength Training to Activate the Quadriceps Muscle After Total Knee Arthroplasty
Background: Progressive strength training is a training modality used in rehabilitation after total knee arthroplasty (TKA). Strength deficits up to 80% in the quadriceps muscle is shown to be present in the operated leg after…
- Trial name
- NCT01713140
- Testing
- 1 strength training set performed until contraction failure
- Where
- Denmark
- Volunteers
- 20 people
- Sponsor
- Copenhagen University Hospital, Hvidovre
Pain, Postoperative
Addition of Popliteal Plexus Block to Continuous Femoral Nerve Block for Total Knee Arthroplasty
The popliteal plexus block has been described as an alternative analgesic postoperative pain treatment for total knee arthroplasty.
- Trial name
- NCT04048889
- Testing
- Ropivacaine 0.5% Injectable Solution
- Where
- Switzerland
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- University Hospital, Geneva
Cryotherapy Effect
Cryocompression After Total Knee Arthroplasty
The overall aim of this study is to evaluate the effectiveness of a cryocompression device after total knee arthroplasty (TKA) compared to standard therapy.
- Trial name
- NCT05395273
- Testing
- Game Ready cryocompression
- Where
- Switzerland
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Applied Sciences and Arts of Southern Switzerland
Arthritis of the Knee
A Randomized, Study to Evaluate the Iovera° Device in Treating Pain Associated With Total Knee Arthroplasty
This study will evaluate the iovera° device in treating pain associated with total knee arthroplasty (TKA). This study will also assess if overall pain medication is reduced following TKA and will investigate the relationship…
- Trial name
- NCT02284113
- Testing
- iovera°
- Where
- 8 sites in United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Pacira Pharmaceuticals, Inc
Complete Contact, Incomplete Contact
Comparison of Post-operative Knee Range of Motion and Functions Between Intraoperative Complete and Incomplete Patellofemoral Articular Contacts in Patients Undergoing Total Knee Arthroplasty
The purpose of this study is to compare clinical outcome in knee range of motion and functions between intraoperative complete and incomplete patellofemoral articular contacts
- Trial name
- NCT05349461
- Testing
- Complete patellofemoral articular contact, Incomplete patellofemoral articular contact
- Where
- Thailand
- Volunteers
- 60 people
- Sponsor
- Navamindradhiraj University
Post Operative Pain, Functional Outcome
Total Knee Arthroplasty in Conjunction With Intra-operative Genicular Nerve Radio-Frequency Ablation
The aim of this study is to compare between conventional Total Knee Arthroplasty (TKA) and Total Knee Arthroplasty (TKA) combined with intra-operative Genicular Nerve Radio-Frequency Ablation (GNRFA), concerning post-operative…
- Trial name
- NCT07381062
- Testing
- Total knee arthroplasty, Genicular nerve radiofrequency ablation
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Ain Shams University
Knee Osteoarthritis
Comparison of Custom and Standard Total Knee Replacements
Total knee arthroplasty (TKA) is the most common surgery in North America and the second most common in Europe. One of the most critical issues for stability and durability of the interventional is the prosthesis-bone geometric…
- Trial name
- NCT06122727
- Testing
- total knee arthroplasty
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- Istituto Ortopedico Rizzoli
Osteoarthritis, Knee
Comparison of Pinless Navigation and Conventional Method in Total Knee Arthroplasty
The purpose of this study is to conduct a prospective randomized clinical trial to compare the accuracy of prosthesis, radiographic alignment, total blood loss, the risk of venous thromboembolism between pinless-navigated total…
- Trial name
- NCT04235283
- Testing
- Primary total knee replacement by pinless navigation (Orthomap Express,Stryker, Michigan), Primary total knee replacement by traditional jig and minimally invasive technique
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- Chang Gung Memorial Hospital
Knee Replacement Arthroplasty, Fibrosis
Knee Stiffness in Fibrosis Diathesis
At the standard follow-up moment one year after primary TKA for gonarthrosis, all patients will be checked for signs of fibrosis diathesis.
- Conditions
- Knee Replacement Arthroplasty, Fibrosis, Dupuytren's Disease
- Trial name
- NCT02294890
- Testing
- Total knee arthroplasty
- Volunteers
- 60 people
- Sponsor
- University Hospital Pellenberg
Arthroplasty, Replacement
Walking Stick Exercise in Patients Underwent Total Knee Arthroplasty
The purpose of this study is to examine whether the effect of "hiking poles exercise" on lower extremity muscular strength, knee range of motion, and quality of life in elderly patients underwent total knee arthroplasty
- Conditions
- Arthroplasty, Replacement, Knee Osteoarthritis
- Trial name
- NCT05030662
- Testing
- Walking stick exercise
- Where
- Taiwan
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- National Taipei University of Nursing and Health Sciences
Orthopedic Surgery, Total Hip Prosthesis
Evaluating the Influence of the Strategy Intraoperative Anesthetic (Desflurane Versus Propofol) on Cognitive and Psychomotor Functions in Output Post Interventional Room Monitoring - COGNIDES
The recovery of cognitive and psychomotor functions is best performed under anesthesia after desflurane when propofol in that obtaining a Aldrete score> 8/10 output of the allowing SSPI.
- Conditions
- Orthopedic Surgery, Total Hip Prosthesis, Total Knee Replacement
- Trial name
- Cognides (NCT02036736)
- Testing
- Intraoperative anesthetic strategy by Propofol, Intraoperative anesthetic strategy by Desflurane
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Knee Osteoarthritis
The Effect of Postoperative "Peanut Ball" Rehabilitation After Total Knee Replacement.
The purpose of this randomized controlled study is to evaluate the effect of postoperative exercise with a "peanut ball" after total knee replacement, on pain, intake of pain killers, knee function, and health-related quality of…
- Trial name
- NCT05137834
- Testing
- Exercise
- Where
- Sweden
- Volunteers
- 300 people
- Sponsor
- Region Skane
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