Clinical trials: Knee Arthroscopic Surgery
Anterior Cruciate Ligament Rupture, Femoral Nerve Block
FNB in ACL Recon Under GA
The investigators will compare the results of sono-guided femoral nerve block in arthroscopic surgery for anterior cruciate ligament reconstruction under general anesthesia.
- Trial name
- NCT06048848
- Testing
- Sono-guided injection, Ropivacaine injection, Saline injection
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- Chuncheon Sacred Heart Hospital
Anterior Cruciate Ligament Tear, Medial Collateral Ligament
A Study to Evaluate the Incrediwear Products Immediately After ACL Repair
To assess the benefits of using the Incrediwear knee products after ACL or ACL+MCL arthroscopic surgery, on the postoperative pain, range of motion and effusion.
- Trial name
- NCT06668376
- Testing
- Leg Sleeve
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Texas Bone and Joint
Osteoarthritis, Knee
Arthroscopy in the Treatment of Degenerative Medial Meniscus Tear
Degenerative meniscal tears are the most common etiology for knee pain, swelling and loss of function. Partial arthroscopic meniscectomy is the most common orthopaedic procedure to treat meniscal tears.
- Trial name
- NCT00549172
- Testing
- Operative (partial arthroscopy), Conservative (diagnostic arthroscopy)
- Where
- 5 sites in Finland
- Volunteers
- 146 people, healthy volunteers welcome
- Sponsor
- Tampere University
Osteoarthritis of the Knee
Surgery Versus No Surgery for Osteoarthritis (OA) of the Knee
The purpose of this study is to discover whether arthroscopic surgery is helpful in controlling the symptoms of osteoarthritis of the knee.
- Trial name
- MRC Knee (NCT00562822)
- Testing
- Arthroscopic surgery, Physical and medical therapy
- Where
- Canada
- Volunteers
- 188 people
- Sponsor
- University of Western Ontario, Canada
Cruciate Ligament Reconstruction
Comparison of Tendon and Muscle-Tendon Semitendinosus Grafts After ACL Reconstruction
Aim: Comparison of tendon to bone ingrowth in bone tunnels and intra-articular remodeling of the graft after anterior cruciate ligament surgery with a muscle-tendon graft and those with a tendon graft.
- Trial name
- CandyStripe (NCT07404046)
- Testing
- ACL reconstruction
- Where
- Croatia
- Volunteers
- 40 people
- Sponsor
- University Hospital Dubrava
Articular Cartilage Disorder of Knee, Cartilage Damage
Human ECM Implanted Within Microfracture Interstices & the Cartilage Defect in the Knee to Regenerate Hyaline Cartilage
HST003 is a human extracellular matrix designed for injection into the subchondral bone following microfracture surgery by an injection into the interstices created by the surgical awl and filling the full defect to help…
- Conditions
- Articular Cartilage Disorder of Knee, Cartilage Damage, Microfractures
- Trial name
- hECM;HST003 (NCT05082831)
- Testing
- microfracture surgery + HST003
- Where
- 5 sites in United States
- Volunteers
- 1 people
- Sponsor
- Histogen
Efficacy of Drugs in Pain Management
Dexamethasone Versus Dexmedetomidine in IPACK Block to Reduce Pain Post Arthroscopic Knee Surgeries
The investigators will test the effects of dexamethasone versus dexmedetomidine as adjuvant to bupivacaine in IPACK Block and it's direct effect in decreasing pain post operative following Arthroscopic knee surgeries
- Trial name
- NCT07024043
- Testing
- Dexamethasone versus Dexmedetomidine in IPACK Block to reduce pain post Arthroscopic knee surgeries, IPACK and multi-modal analgesic regimen
- Where
- Egypt
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Pain, Postoperative
Comparing Dexamethasone With Dexmedetomidine as Additives to Bupivacaine in Adductor Canal Block for Knee Arthroscopy.
a comparison shall be conducted between dexamethasone accompanied by bupivacaine, on one hand, and dexmedetomedine accompanied by bupivacaine on the other hand and a control group for pain-free knee arthroscopic surgeries.
- Trial name
- NCT04631822
- Testing
- Spinal anaesthesia, ultrasound-guided Adductor Canal Block + dexamethasone, ultrasound-guided Adductor Canal Block + dexmedetomedine
- Where
- Egypt
- Volunteers
- 135 people
- Sponsor
- Rasha Hamed
Patients Eligible for Elective Lower Extremity Femoral Nerve Surgery, Knee Arthroscopic Surgery
Clinical Observation of Bupivacaine Liposome for Lower Extremity Nerve Block
This prospective, sequential dose-finding clinical observational study aims to estimate the median effective concentration (EC50) and the 95% effective concentration (EC95) of liposomal bupivacaine for ultrasound-guided femoral…
- Trial name
- NCT07366905
- Testing
- Liposomal bupivacaine, 266mg
- Where
- China
- Volunteers
- 79 people
- Sponsor
- Hainan Medical College
Arthroplasty, Replacement, Knee, Hip, Postoperative Nausea and Vomiting
The Effect of White and Pink Noise in Patients Undergoing Total Hip and Knee Arthroplasty
This study aims to investigate the effects of preoperative white noise and pink noise interventions on sleep quality, anxiety, postoperative pain, nausea, and physiological parameters in patients undergoing elective total hip…
- Conditions
- Arthroplasty, Replacement, Knee, Hip, Postoperative Nausea and Vomiting, Anxiety, Postoperative Pain After Arthroscopic Knee Surgery
- Trial name
- NCT07858058
- Testing
- White Noise Intervention, Pink Noise Intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 165 people
- Sponsor
- Ataturk University
Pain
Adding Intra-articular Dexmedetomidine to Levobupivacaine for Postoperative Analgesia in Arthroscopic Knee Surgery
The purpose of this study to search efficacy of intra-articular dexmedetomidine addition to levobupivacaine for postoperative analgesia in arthroscopic knee surgery.
- Trial name
- NCT01918917
- Testing
- Levobupivacaine, Dexmedetomidine, Morphine
- Volunteers
- 60 people
- Sponsor
- TC Erciyes University
Knee Arthropathy
The Efficacy Of Ultrasound-Guided Adductor Canal Block for Arthroscopic Knee Surgery
The ultrasound-guided selective blockade of the saphenous nerve in the adductor canal provides effective analgesia and reduces postoperative pain in patients undergoing arthroscopic medial meniscectomy.
- Trial name
- NCT04010916
- Testing
- Group Preoperatively Adductor Canal Block, Group Preoperatively Tourniquet Adductor Canal Block, Group Postoperatively Adductor Canal Block
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Medipol University
Anterior Cruciate Ligament Injury
Clinical Comparison of Femoral Nerve Versus Adductor Canal Block Following Anterior Ligament Reconstruction
This study will examine the potential differences between femoral nerve blockade (FNB) and adductor canal blockade (ACB) for pain control and quadriceps muscle activation for patients following anterior cruciate ligament (ACL)…
- Trial name
- FNB vs ACB (NCT03704376)
- Testing
- 30 ml of 0.2% ropivacaine, 15 ml of 0.2% ropivacaine, 100 mcg clonidine
- Where
- United States
- Volunteers
- 125 people
- Sponsor
- The University of Texas Health Science Center, Houston
Patients Undergoing Knee Arthroscopic Ligament Surgery
Construction and Application of the Whole Course Management Scheme for Knee Arthroscopic Ligament Surgery Patients Based on "Internet +"
On the basis of the conventional diagnosis and treatment mode, the experimental group added an application program for closed-loop management of the entire course of the disease.
- Trial name
- NCT07362849
- Testing
- Added applications for closed-loop management of the entire disease course
- Volunteers
- 60 people
- Sponsor
- The Fourth Affiliated Hospital of Zhejiang University School of Medicine
Pain, Postoperative, Knee Arthroscopy
Postoperative Pain Between ACB and FNB After ACLR
The aim of this study is to compare the efficacy in pain relief within 24 hours between adductor canal block and femoral nerve block after anterior cruciate ligament reconstruction with hamstring graft.
- Conditions
- Pain, Postoperative, Knee Arthroscopy, Anterior Cruciate Ligament/Surgery
- Trial name
- NCT02411890
- Testing
- Adductor canal block (active), Femoral nerve block (active)
- Where
- Thailand
- Volunteers
- 60 people
- Sponsor
- Thammasat University
Arthroscopic Surgery, Nutrition
The Effect of Nutritional Education on Post-Arthroscopic Nutritional Status
The purpose of this study is to determine how patient nutrition effects post-operative outcomes for patients undergoing arthroscopic surgery
- Conditions
- Arthroscopic Surgery, Nutrition, Orthopedic Surgery, Shoulder Arthroscopic Surgery
- Trial name
- NCT07723742
- Testing
- Standard of Care, Nutritional Video
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- University of Alabama at Birmingham
ACL Injury, Hip Injuries
Muscle O2 Saturation and Hemoglobin Levels During Rehabilitation From Arthroscopic Surgery
This study will utilize the Moxy wearable sensor to measure muscle oxygen saturation levels in athletes following lower extremity surgery (ACL or Hip arthroscopy) to evaluate their Return-to-Play.
- Trial name
- NCT05488054
- Testing
- Physical Therapy, Monitored Work-out, Moxy Oxygen Sensor Device
- Where
- 2 sites in United States
- Volunteers
- 226 people, healthy volunteers welcome
- Sponsor
- University Hospitals Cleveland Medical Center
Arthroscopic Knee Ligament Reconstruction
A Novel Single-puncture Triple Nerve Block; Sciatic, Obturator, Femoral Technique (SOFT), as a Sole Anesthesia for Knee Surgeries
This study aims to describe and to evaluate the effectiveness (success rate) of a supine ultrasound (US) guided single-puncture sciatic, obturator and femoral neve block technique (SOFT block) in knee surgery.
- Trial name
- NCT02951520
- Testing
- new technique for lower limb nerve blocks using a single skin puncture (SOFT block)
- Where
- United Arab Emirates
- Volunteers
- 50 people
- Sponsor
- Healthpoint Hospital
Postoperative Pain
Efficacy of Intra-articular Neostigmine Versus Ketamine for Postoperative Analgesia in Arthroscopic Knee Surgery
To compare the efficacy of intra-articular administration of neostigmine versus ketamine as adjuvant analgesics after knee arthroscopy.
- Trial name
- NCT03248648
- Testing
- Neostigmine, ketamine
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Assiut University
Anterior Cruciate Ligament Rupture, Anterior Cruciate Ligament (ACL) Tear
Active Noise-Cancelling Headphones With Closed-Loop Communication During Arthroscopic ACL Reconstruction
Operating room noise may interfere with communication, concentration, and surgical workflow. Active noise-cancelling (ANC) headphones can reduce background auditory distractions; however, their potential benefit during surgery…
- Conditions
- Anterior Cruciate Ligament Rupture, Anterior Cruciate Ligament (ACL) Tear, Anterior Cruciate Ligament Injury
- Trial name
- ANC-ACL-2026 (NCT07589582)
- Testing
- Active Noise-Cancelling Headphones With Closed-Loop Communication, Standard Operating Room Communication
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital