Clinical trials: Knee Arthroscopy
Knee Injuries
Follow-Up Study Evaluating The Long Term Safety and Efficacy of BST-CarGel and Microfracture Repair of the Knee
This follow-up study will evaluate the effects of BST-CarGel® application to a microfractured lesion (investigational) and microfracture alone (control) for up to 5 years from treatment in subjects, treated under Protocols…
- Trial name
- NCT01246895
- Testing
- Microfracture with BST-CarGel, Microfracture without BST-CarGel
- Where
- 16 sites in Canada, Spain
- Volunteers
- 67 people
- Sponsor
- Piramal Healthcare Canada Ltd
Arthroscopic Knee Surgery
Study to Find Optimal Dose of Local Spinal Anesthetic (Mepivacaine) Combined With Narcotic (Fentanyl) For Knee Surgery
Prolonged motor block and delayed ability to walk are limitations of spinal anesthesia in ambulatory (same-day) surgery. This can be improved by lowering the dose of local anesthetic (a medication that, when injected around…
- Trial name
- NCT01701102
- Testing
- Mepivacaine (24 mg) plus fentanyl, Mepivacaine (27 mg) plus fentanyl, Mepivacaine (30 mg) plus fentanyl
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Hospital for Special Surgery, New York
Anterior Cruciate Ligament Tear, Knee Meniscus Tear
Adductor Canal Block Versus Femoral Block on Pain and Quadriceps Strength
The purpose of this study is to compare the effects of a femoral nerve block vs. an adductor canal block on pain and quadriceps muscle strength for knee arthroscopy surgery.
- Trial name
- NCT05190120
- Testing
- Femoral Nerve Block, Adductor Canal Nerve Block, preoperative Femoral Nerve Block using 20ml of 0.5% ropivacaine
- Where
- United States
- Volunteers
- 132 people
- Sponsor
- University of California, San Francisco
Knee Injury
Decadron as Adjuvant in Femoral Nerve Blocks in Knee Arthroscopy
If preservative-free dexamethasone 0.1 mg/kg (max dose 4 mg) is added to ropivacaine 0.5% 2 mg/kg (max dose 100 mg), then post-PACU opioid consumption will be reduced by 33%.
- Trial name
- NCT01971645
- Testing
- Dexamethasone, Ropivacaine
- Where
- United States
- Volunteers
- 77 people
- Sponsor
- Nationwide Children's Hospital
Arthroscopic Knee Surgery
A Pilot Study to Determine the Efficacy of Intravenous Ibuprofen for Pain Control Following Arthroscopic Knee Surgery
The intent of this study is to assess the analgesic efficacy of IV ibuprofen when administered at induction of anesthesia. Results from this pilot study will be used to design and determine the appropriate statistical power for a…
- Trial name
- NCT01650519
- Testing
- IV ibuprofen, IV ketorolac
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- Cumberland Pharmaceuticals
Disorder of Knee, Anesthesia
Spinal Anesthesia With Hyperbaric Levobupivacaine 0.75% for Ambulatory Knee Arthroscopy
The purpose of this study is to evaluate motor block probability throughout time and clinical profile when using three different doses of HLBP 0.75% (7.5, 9.37 and 11.25 mg) by a unilateral spinal block technique.
- Trial name
- levobupi (NCT01881087)
- Testing
- Hyperbaric Levobupivacaine 0.75%
- Where
- Colombia
- Volunteers
- 180 people
- Sponsor
- Fundacion Clinica Valle del Lili
Knee Injuries, ACL Injury
Opiates Prescribing for Knee Arthroscopies and ACL Reconstruction
The purpose of the study is to determine if opiates are required to achieve adequate analgesia after knee arthroscopy and ACL reconstruction in outpatient surgery.
- Trial name
- NCT03876743
- Testing
- Group 1-Knee Arthroscopy, Group 2-Knee Arthroscopy, Group 1-ACL reconstruction
- Where
- United States
- Volunteers
- 201 people
- Sponsor
- Northwestern University
Knee Arthroscopy, Acute Pain
"Comparison of Intra-articular of 0.2% Ropivacaine vs. 0.75% Ropivacaine in Postoperative of Knee Arthroscopy"
All patients with acute lesions that attend the orthopedic and trauma center of the ABC medical center are invited to participate in the study.
- Trial name
- ropivacaine (NCT05807945)
- Testing
- Ropivacaine 0.75% Injectable Solution, Ropivacaine 0.2% Injectable Solution
- Where
- Mexico
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Paola M Zamora Munoz
Venous Thromboembolism, Haemorrhage
Efficacy of RIvaroxaban for Prevention of Venous Thromboembolism After Knee Arthroscopy
Study Objective: To assess the value of Rivaroxaban for the prevention of venous thromboembolism (VTE) after knee arthroscopy (KA) taking the placebo as standard of reference.
- Trial name
- ERIKA (NCT01629381)
- Testing
- Rivaroxaban
- Where
- 9 sites in Italy
- Volunteers
- 500 people
- Sponsor
- University of Padova
Knee Arthroscopy
Chloroprocaine Spinal for Outpatient Knee Surgery
Outpatient knee surgeries with duration of less than one hour pose a challenge to the use of spinal anesthesia given that traditional agents remain in effect for 2-3 hours, thus creating a mismatch between length of surgery and…
- Trial name
- NCT03365752
- Testing
- Chloroprocaine, Mepivacaine, General Anesthetics
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- Hospital for Special Surgery, New York
Meniscectomy
Dose Response of Ketorolac in Knee Arthroscopy
Ketorolac is administered as current practice to the majority of patients undergoing knee arthroscopy, the appropriate dose of ketorolac to be administered has not been evaluated.
- Trial name
- NCT02181426
- Testing
- Ketorolac Dose
- Where
- United States
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Osteoarthritis, Knee
Arthroscopy in the Treatment of Degenerative Medial Meniscus Tear
Degenerative meniscal tears are the most common etiology for knee pain, swelling and loss of function. Partial arthroscopic meniscectomy is the most common orthopaedic procedure to treat meniscal tears.
- Trial name
- NCT00549172
- Testing
- Operative (partial arthroscopy), Conservative (diagnostic arthroscopy)
- Where
- 5 sites in Finland
- Volunteers
- 146 people, healthy volunteers welcome
- Sponsor
- Tampere University
Knee Arthroscopy
Assessing the Effects of Sublingual Sufentanil 30 µg on Postoperative Recovery
A pilot study to evaluate the effect of incorporating sublingual sufentanil into our perioperative opioid regimen for ambulatory orthopedic surgery.
- Trial name
- NCT04561375
- Testing
- Sufentanil, Fentanyl
- Where
- United States
- Volunteers
- 61 people
- Sponsor
- The Cleveland Clinic
Bone Marrow Edema, Knee Pain Chronic
Subchondroplasty® Knee RCT
This is a multi-center, prospective, single-blinded, two-arm study, randomized to include approximately 134 subjects treated with Subchondroplasty (SCP) + Arthroscopy and 67 subjects with arthroscopy alone.
- Conditions
- Bone Marrow Edema, Knee Pain Chronic, Knee Osteoarthritis, Osteoarthritis, Knee
- Trial name
- PRESERVE Knee (NCT03112200)
- Testing
- Subchondroplasty with Arthroscopy, Arthroscopy Alone
- Where
- 13 sites in United States, Canada
- Volunteers
- 131 people
- Sponsor
- Zimmer Biomet
Internal Derangement of Knee
Infrapatellar Nerve Block for Post-operative Knee Arthroscopy Pain Control
The purpose of this study is to determine whether infrapatellar branch of the saphenous nerve blocks are effective in decreasing analgesic use, promoting earlier mobility, and improving long term outcome scores after knee…
- Trial name
- NCT01279447
- Testing
- 0.25% Bupivacaine, Normal Saline
- Where
- United States
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Pain
Comparison of a Pain Pump Versus Injectable Medication for Analgesia in Knee Arthroscopy
Hypothesis: Ropivacaine, morphine and ketorolac injected after knee arthroscopy is as effective as this solution plus ropivacaine administered intra-articularly for twenty-four hours.
- Trial name
- NCT01242644
- Testing
- pain pump containing ropivacaine, saline pain pump with injectable medication, ropivacaine, ketorolac , morphine sulfate
- Volunteers
- 48 people
- Sponsor
- University of South Alabama
Knee Injuries
Trial Comparing BST-CarGel and Microfracture in Repair of Articular Cartilage Lesions in the Knee
This study will investigate whether the treatment of damaged cartilage in the knee with BST-CarGel will increase the amount and quality of cartilage repair tissue when compared with microfracture alone.
- Trial name
- NCT00314236
- Testing
- BST-CarGel with Microfracture, Microfracture without BST-CarGel
- Where
- 18 sites in Canada, South Korea and 1 more
- Volunteers
- 80 people
- Sponsor
- Piramal Healthcare Canada Ltd
Knee Injury
Needleless Jet Injected (J-Tip) Lidocaine in Children Undergoing Regional Anesthesia Prior to Knee Arthroscopy
Purpose of this study is to investigate the pain outcomes and satisfaction of pain relief for pediatric patients receiving needleless jet-injected (J-Tip) lidocaine prior to regional anesthesia with femoral and/or sciatic nerve…
- Trial name
- NCT02649322
- Testing
- J-Tip, Syringe and 25 gauge needle
- Where
- United States
- Volunteers
- 115 people
- Sponsor
- Orlando Health, Inc.
Meniscus Tear, Meniscus Lesion
PROPER Trial of Pain and Inflammation After Knee Arthroscopy
The purpose of this study is to determine if ceftriaxone administered postoperatively via intravenous injection reduces postoperative visual analog scale (VAS) pain scores and narcotic consumption in patients undergoing knee…
- Conditions
- Meniscus Tear, Meniscus Lesion, Cartilage Injury
- Trial name
- PROPER (NCT05149287)
- Testing
- Ceftriaxone
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Austin V Stone
Meniscus Tear, Knee Meniscus Injury
High-Purity Type I Collagen Augmentation in Meniscal Repair
This prospective, single-arm feasibility study evaluates the safety, procedural feasibility, and early clinical outcomes of High-Purity Type I Collagen used as an adjunct in arthroscopic meniscal repair.
- Conditions
- Meniscus Tear, Knee Meniscus Injury, Meniscal Repair, Knee Arthroscopy (for Diagnostic or Therapy)
- Trial name
- NCT07352410
- Testing
- High-Purity Type I Collagen
- Where
- India
- Volunteers
- 18 people
- Sponsor
- Adichunchanagiri Institute of Medical Sciences, B G Nagara