Clinical trials: Knee Arthrosis,
Arthritis, Osteoarthritis
Tanezumab in Osteoarthritis of the Knee
Test the efficacy and safety of 3 doses in Osteoarthritis of the knee in patients.
- Trial name
- NCT00733902
- Testing
- tanezumab
- Where
- 82 sites in United States
- Volunteers
- 697 people
- Sponsor
- Pfizer
Tranexamic Acid, Knee Osteoarthritis
Tranexamic Acid in Major Orthopedic Surgery: Comparison of 3 Dosage Regimen
Tranexamic acid has been shown to be effective in reducing blood loss and transfusion in orthopedic surgery. It remains unknown the ideal therapeutic regimen.
- Conditions
- Tranexamic Acid, Knee Osteoarthritis, Ankle Osteoarthritis, Bleeding
- Trial name
- NCT03573245
- Testing
- Tranexamic Acid
- Volunteers
- 210 people
- Sponsor
- CUF Santarém Hospital
Osteo Arthritis Knee, Joint Diseases
SakuraBead Used as Resorbable Embolic for Genicular Artery Embolization
An open label, prospective, two-arm, multicenter, randomized controlled trial comparing SakuraBead genicular artery embolization (GAE) with a control (corticosteroid injection).
- Conditions
- Osteo Arthritis Knee, Joint Diseases, Musculoskeletal Diseases, Rheumatic Diseases
- Trial name
- SURE (NCT06550024)
- Testing
- SakuraBead Resorbable Microspheres, Corticosteroid Injection
- Where
- 8 sites in United States, Georgia and 2 more
- Volunteers
- 89 people
- Sponsor
- CrannMed
Knee Osteoarthritis, Rheumatoid Arthritis
Freedom® Total Knee System for Treatment of Osteoarthritis, Rheumatoid Arthritis or Post-traumatic Arthritis
A prospective, multi-centre, non-comparative, post-market clinical follow-up study to evaluate the survivorship, safety and performance of the Freedom® Total Knee System in the treatment of approximately 450 subjects who in the…
- Conditions
- Knee Osteoarthritis, Rheumatoid Arthritis, Post-traumatic Osteoarthritis
- Trial name
- Freedom®450 (NCT04033588)
- Testing
- Freedom® Total Knee System
- Volunteers
- 450 people
- Sponsor
- Meril Life Sciences Pvt. Ltd.
Knee Osteoarthritis
Effectiveness Of MM & Kinesotaping In The Female Patients Of KO To Improve Pain & Functional Mobility RCT
to find out the Effectiveness Of Mobilization With Movement And Kinesotaping In The Female Patients Of Knee Osteoarthritis To Improve Pain And Functional Mobility
- Trial name
- NCT05868473
- Testing
- Mobilization With Movement, Kinesotaping
- Where
- Pakistan
- Volunteers
- 56 people
- Sponsor
- Superior University
Arthritis, Knee Osteoarthritis
Immediate Effects Of Alliance Therapy In Modulation Of Pain And Disability In Subjects With Knee Osteoarthritis
INTRODUCTION: The Osteoarthritis (OA) is the most common type of joint disease, its features include joint space narrowing, osteophytes formation of the joint margins, motor deficit, reduced strength, and persistent pain.
- Trial name
- NCT03928054
- Testing
- Kinesio Taping and therapeutic alliance
- Where
- Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Faculdade de Ciências Médicas da Santa Casa de São Paulo
Knee Osteoarthritis
Self-managed vs Supervised Exercise for Knee OA
Knee osteoarthritis (OA) is a common painful condition associated with pain and disability. OA healthcare costs the Danish society 4.6 billion DKK more per year than the non-OA population and we lack evidence on how best to…
- Trial name
- SELFIT (NCT07210931)
- Testing
- Self-managed exercise in a fitness center, Supervised Exercise
- Volunteers
- 300 people
- Sponsor
- Marius Henriksen
Patellofemoral Pain Syndrome
Muscle Strength Loss and Its Effect on Knee Cap Motion in Volunteers With Anterior Knee Pain
Background: Researchers are interested in how the muscles affect the movement of the knee cap. These muscles may be related to different kinds of knee pain that are not caused by an injury or a disease.
- Trial name
- NCT01862731
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- National Institutes of Health Clinical Center (CC)
Osteoarthritis, Knee, Knee Pain Chronic
Impact of Dexamethasone Route on Pain and Inflammation in iPACK With ACB for Knee Arthroplasty
"The Effect of Dexamethasone Administration Route on Pain and Inflammatory Response in iPACK With ACB for Total Knee Arthroplasty" - written in plain language according to ClinicalTrials.gov standards: The goal of this clinical…
- Conditions
- Osteoarthritis, Knee, Knee Pain Chronic, Arthropathy of Knee
- Trial name
- NCT07180953
- Testing
- NaCl 0.9%, Dexamethasone 4mg
- Where
- Poland
- Volunteers
- 90 people
- Sponsor
- Poznan University of Medical Sciences
Knee Disease, Knee Osteoarthritis
Biplanar PSI Slope-reducing MOWHTO With Tibial Tuberosity Serving as Hinge Axis: Cadaveric Study
Six cadaveric lower limbs will have PSI slope-reducing MOWHTO performed on and accuraccy of biplanar correction will be assessed.
- Conditions
- Knee Disease, Knee Osteoarthritis, Knee Injuries and Disorders
- Trial name
- NCT05448742
- Testing
- Biplanar PSI slope-reducing MOWHTO.
- Where
- Poland
- Volunteers
- 6 people
- Sponsor
- Artromedical Konrad Malinowski Clinic
Knee Osteoarthritis
Effects of Concurrent Exercise Combinations in Knee Osteoarthritis:
This study will include 3 different groups of intervention. First group of knee osteoarthritis patients will be applied both strengthening and 30 minutes bicycle exercises in the same session, 2 days strecthing exercises and 30…
- Trial name
- NCT05054686
- Testing
- Stretching and Aerobic Exercise at Clinic, Strenghthening and Aerobic Exercise, Strengthening, Stretching and Aerobic Exercises at clinic
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Symptomatic Osteoarthritis of the Knee
Intra-articular Injections for Knee Osteoarthritis: A Single Blinded Prospective Randomized Trial
To investigate the clinical benefit of intra-articular injections of saline in patients with symptomatic osteoarthritis of the knee and compare the clinical response of saline to the current standard treatment with…
- Trial name
- NCT02995083
- Testing
- 40 mg Depo-Medrol in 1 ml, 9 ml of 1% lidocaine, Normal Saline 10 ml, Air 10 ml
- Sponsor
- Rush University Medical Center
Knee Osteoarthritis
Comparison Between Two Total Knee Prosthesis Medacta GMK Sphere and Medacta GMK PS
The purpose of the study is to compare the clinical outcome after two total knee endoprosthesis designs Medacta GMK Sphere and Medacta GMK PS. Primary outcome measures KOOS, Forgotten Knee Score and range of motion.
- Trial name
- NCT03896451
- Testing
- Total knee endoprothesis
- Where
- Switzerland
- Sponsor
- Kantonsspital Winterthur KSW
Osteo Arthritis Knee
The Relationship Between Cannabis Use, Biomarkers, Tissue Cannabinoid Levels and Clinical Outcomes in Patients With OA
Osteoarthritis (OA), the most common form of arthritis, is a leading cause of disability, affecting the quality of life, pain, and physical functioning of 4.6 million Canadians.
- Trial name
- NCT04971629
- Where
- Canada
- Volunteers
- 1,200 people
- Sponsor
- University Health Network, Toronto
Knee Osteoarthriis and Oxidative Stress
Do Obese Patients With Primary Knee Osteoarthritis Benefit From a Single Bout of Moderate Intensity Aerobic Exercise?
Background: Obesity and degenerative joint disease are typically concomitant . Each are in the course of aerobic focus and excited inflammatory response.
- Trial name
- NCT03927339
- Testing
- pre and post excercise group
- Where
- Egypt
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Knee Arthritis Osteoarthritis, Knee Arthritis, Osteoarthritis
Efficacy and Safety of GNSC-001 Intra-articular Injection for Knee Osteoarthritis
The goal of this clinical trial is to learn if GNSC-001 works to treat knee osteoarthritis in adults. It will also learn about the safety of GNSC-001. The main questions it aims to answer are: 1.
- Conditions
- Knee Arthritis Osteoarthritis, Knee Arthritis, Osteoarthritis, Knee Arthritis, Knee Arthritis Disease
- Trial name
- RAPHAEL (NCT07831577)
- Testing
- Gene Therapy GNSC-001
- Volunteers
- 240 people
- Sponsor
- Genascence Corporation
Gonarthrosis
Functional Recovery After Medial Monocompartmental Knee Prosthesis: One Day Protocol Versus Fast Protocol
The study is defined as prospective, randomized, interventional single-center; the general aim is to evaluate the post-operative recovery of the patient who carries out rehabilitation with the one day protocol (Group A), compared…
- Trial name
- UKA-L2086 (NCT06302075)
- Testing
- One Day Rehabilitation, Fast Rehabilitation
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio
Knee Osteoarthritis
Comparison of Conventional and Cooled Radiofrequency Ablation in Knee Osteoarthritis
The aim of this study was to examine and compare the effects of conventional and cooled radiofrequency ablation on pain and disability levels in patients with knee pain resistant to other treatments due to knee osteoarthritis.
- Trial name
- NCT06863181
- Testing
- Radiofrequency ablation
- Where
- Turkey (Türkiye)
- Volunteers
- 26 people
- Sponsor
- Gaziler Physical Medicine and Rehabilitation Education and Research Hospital
Osteoarthritis, Knee
Does Tourniquet Use in Total Knee Replacement Improve Fixation
Although a tourniquet may reduce bleeding during total knee replacement (TKA), and thereby improve fixation, it might also cause complications.
- Trial name
- NCT01470482
- Testing
- No use of tourniquet, Tourniquet
- Where
- Sweden
- Volunteers
- 50 people
- Sponsor
- Per Aspenberg
Knee Osteoarthritis
Investigating the Role of Motivational Interviewing in Swedish Patients Undergoing Knee Arthroplasty
Knee arthroplasty is a successful surgical treatment for end-stage osteoarthritis. Most patients are satisfied with the result, however, 10% of the patients have remained dissatisfied over the last decades despite the advantages…
- Trial name
- NCT05940246
- Testing
- Motivational Interviewing
- Where
- Sweden
- Volunteers
- 149 people, healthy volunteers welcome
- Sponsor
- Region Stockholm