Clinical trials: Knee Extension
Osteoarthritis (OA) of the Hip, Osteoarthritis (OA) of the Knee
Extended Post-operative Oral TXA in Primary THA
The goal of this clinical trial is to learn if extended post-operative oral tranexamic acid (TXA) - a medication that reduces bleeding by slowing the breakdown of blood clots - can improve functional recovery following surgery in…
- Trial name
- NCT07685743
- Testing
- Extended oral tranexamic acid regimen
- Volunteers
- 170 people
- Sponsor
- Oregon Health and Science University
Postoperative Pain
Safety and Effectiveness of Tramadex-OD After Knee Arthroscopy
Extended-release tramadol is indicated for the management of moderate to severe pain in adults who require around-the-clock treatment.
- Trial name
- NCT01024348
- Testing
- extended-release tramadol, paracetamol
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- Shaare Zedek Medical Center
Osteoarthritis, Knee
A Study of the Efficacy and Safety of EUFLEXXA™ for Treatment of Painful Osteoarthritis of the Knee
This multicenter, randomized, double-blind study will be performed in approximately 600 subjects with chronic idiopathic osteoarthritis (OA) of the knee. An open-label safety extension will follow.
- Trial name
- NCT00379236
- Testing
- EUFLEXXA™
- Where
- United States
- Volunteers
- 588 people, healthy volunteers welcome
- Sponsor
- Ferring Pharmaceuticals
Osteoarthritis
Analgesic Efficacy and Safety Study of Naproxcinod in Subjects With Osteoarthritis of the Knee
To study the efficacy and safety of naproxcinod vs. placebo and naproxen in the treatment of signs and symptoms of Osteoarthritis.
- Trial name
- NCT00542555
- Testing
- Naproxcinod 375 mg, Naproxen, Naproxcinod 750 mg
- Volunteers
- 918 people
- Sponsor
- NicOx
Cerebral Palsy
Safety and Performance of Agilik in CP
The purpose of this post market study is to demonstrate the safety and performance of a powered extension assist (EA) knee ankle foot orthosis (KAFO), or EA-KAFO, in individuals with knee extension deficiency due to cerebral…
- Trial name
- Agilik (NCT05746871)
- Testing
- Agilik, standard care
- Where
- Italy
- Volunteers
- 9 people
- Sponsor
- IRCCS Eugenio Medea
Arthritis of Knee
Study of Surgical Technique With Use of Single-radius Prosthesis in Total Knee Replacement
The purpose of this study is to clinically demonstrate a phenomenon of measurement error that can occur during placement of a specific type of total knee replacement prosthesis (single radius femoral component) using a certain…
- Trial name
- NCT01505452
- Where
- 2 sites in United States
- Volunteers
- 43 people
- Sponsor
- Athens Orthopedic Clinic, P.A.
Osteoarthritis Knee
Gel-One Treatment in Knee Osteoarthritis
The purpose of this study is to determine whether Gel-One demonstrates a superior effectiveness in osteoarthritis (OA) knee pain compared with phosphate buffered saline (PBS) injections.
- Trial name
- NCT01934218
- Testing
- Gel-One, PBS
- Where
- 41 sites in United States
- Volunteers
- 814 people
- Sponsor
- Seikagaku Corporation
Osteoarthritis
Etoricoxib in the Treatment of Osteoarthritis (MK-0663-007)
The purpose of this study is to evaluate the safety and efficacy of etoricoxib in the treatment of osteoarthritis of the knee.
- Trial name
- NCT00242489
- Testing
- MK0663, etoricoxib / Duration of Treatment: Part I (6 weeks), Part II (8 weeks)
- Volunteers
- 1,167 people
- Sponsor
- Organon and Co
Pain
Topical Use of 20% Beta Caryophyllene Alone And In Combination With 0.025% Capsaicin for Pain Caused by Osteoarthritis Of The Knee
This study consists of a randomized, double-blind, placebo-controlled crossover trial with open label extension evaluating a topical natural health cream containing ß-caryophyllene alone and in combination with 0.025% capsicum…
- Trial name
- NCT03152578
- Testing
- BetaC + Capsaicin Topical Cream, BetaC Topical Cream
- Where
- Canada
- Volunteers
- 56 people
- Sponsor
- Panag Pharma Inc.
Osteoarthritis
Extension Study Of Tanezumab In Osteoarthritis
Safety extension study of Phase 3 Osteoarthritis trials with Tanezumab
- Trial name
- NCT00809783
- Testing
- tanezumab
- Where
- 226 sites in United States
- Volunteers
- 2,147 people
- Sponsor
- Pfizer
Muscle Weakness
The Immediate Effect of Combined Terminal Knee Extension Exercise With Audible Cues
Typically, patients perform TKE by themselves after exercise prescription. The investigators thought that a lack of attention and preferred speed of patients might not provide the best outcome.
- Trial name
- NCT06565325
- Testing
- Exercise + Audible Cues, Exercise
- Where
- Thailand
- Volunteers
- 30 people
- Sponsor
- Mahidol University
Knee Osteoarthritis
A Multicenter, Postmarket Surveillance Study of Subjects With the Canary canturioTM te Tibial Extension
The objectives of this prospective observational cohort study are to evaluate the safety, reliability, reproducibility, and accuracy of the Canary canturioTM te post-TKA.
- Trial name
- NCT06040827
- Testing
- Total Knee Arthroplasty
- Where
- 7 sites in United States
- Volunteers
- 626 people
- Sponsor
- Canary Medical
Osteoarthritis (OA) of the Knee
Novel Extended-Release Bupivacaine Polymer for Sustained Pain Relief Following Total Knee Arthroplasty
Participants are being invited to take part in a research study about pain control after total knee replacement surgery (also called total knee arthroplasty or TKA).
- Trial name
- NCT07775248
- Testing
- Periarticular Injection, Adductor Canal Block, Bupivacaine-Meloxicam
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Henry Ford Health System
Knee Osteoarthritis
A Multicenter, Open-Label, Single-Arm Extension Study to Evaluate the Safety and Efficacy of FURESTEM-OA-Kit Inj. in Knee Osteoarthritis Patients Who Received Placebo in the K0701 Phase 2a Trial
A Multicenter, Open-Label, Single-Arm Extension Study to Evaluate the Safety and Efficacy of FURESTEM-OA-Kit Inj. in Knee Osteoarthritis Patients Who Received Placebo in the K0701 Phase 2a Trial
- Trial name
- NCT07754175
- Where
- 2 sites in South Korea
- Volunteers
- 36 people
- Sponsor
- Kang Stem Biotech Co., Ltd.
Knee, ACL
Restoration of Knee Extension After ACL Reconstruction
The purpose of this study is to determine whether the addition of a home-based high-intensity knee extension stretching device (Ermi Knee Extensionater) to standard postoperative physical therapy improves recovery of full knee…
- Trial name
- NCT07685561
- Testing
- Standard Physical Therapy, Ermi Knee Extensionater
- Where
- United States
- Volunteers
- 58 people
- Sponsor
- University of Alabama at Birmingham
Osteoarthritis, Knee
Zero Degree Knee Positioner for Improved Earley Knee Extension Following Total Knee Arthroplasty
Studies have demonstrated that early rehabilitation interventions following knee arthroplasty (TKA) can shorten the time needed to regain baseline extension/full extension and gait mechanics.
- Trial name
- NCT05678231
- Testing
- Zero Degree Knee Positioner
- Where
- United States
- Volunteers
- 154 people
- Sponsor
- Prisma Health-Midlands
Hamstring Tightness, Lumbar Lordosis
Hamstring Tightness and Lumbar Lordosis Angel Across Functional Sitting Posture.
The goal of this observational study is to learn about the relationship between hamstring tightness and the lumbar lordosis angle in sedentary adults across different sitting postures.
- Conditions
- Hamstring Tightness, Lumbar Lordosis, Sedentary Behavior, Posture Sitting Position
- Trial name
- LLA-HT (NCT07682142)
- Testing
- Hamstring tightness and lumbar lordosis assessment
- Where
- Egypt
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Cairo University
Osteochondral Defect
Follow-Up Study Evaluating the Long Term Outcome of ChondroMimetic in the Treatment of Osteochondral Defects in the Knee
To investigate the long-term efficacy and safety of the medical device, ChondroMimetic, in subjects who were treated in the interventional study 0MCM0107 for osteochondral defects of the knee.
- Trial name
- NCT03385642
- Testing
- ChondroMimetic
- Where
- Hungary
- Volunteers
- 15 people
- Sponsor
- Collagen Solutions