Clinical trials: Knee Instability
Ligament Injury, Ligament; Laxity
Methylsulfonylmethane on Knee Laxity
The proposed research will focus on determining the effect of methylsulfonylmethane (MSM) on knee laxity changes through the menstrual cycle in young active females.
- Conditions
- Ligament Injury, Ligament; Laxity, Tendon Rupture, Tendon Injuries
- Trial name
- NCT03747198
- Testing
- methylsulfonylmethane
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Rupture of the Anterior Cruciate Ligament With Instability of the Knee Joint
Hamstrings Autograft Versus Tibialis Allograft for Reconstruction of Anterior Cruciate Ligament
Patients suffering from a rupture of the anterior cruciate ligament (ACL) with instability of the knee joint are treated with an operative ACL-reconstruction: one group of patients with a reconstruction with an autograft tendon…
- Trial name
- NCT00510848
- Testing
- autograft tendon, allograft tendon
- Where
- Belgium
- Volunteers
- 40 people
- Sponsor
- University Hospital, Ghent
Patella-Dislocation, Patellofemoral Osteoarthritis
A Prospective Randomized Study of Medial Patellofemoral Ligament (MPFL) Reconstruction
The operative management of chronic patellar instability has been controversial. Medial patellofemoral ligament reconstruction has gained success recently and might be superior to other soft-tissue procedures.
- Conditions
- Patella-Dislocation, Patellofemoral Osteoarthritis, Patellar Instability
- Trial name
- NCT00816647
- Testing
- Patellofemoral stabilizing surgery
- Where
- Finland
- Volunteers
- 50 people
- Sponsor
- Finnish Defense Forces
Anterior Cruciate Ligament Rupture
Anterior Cruciate Ligament Rupture
The assess results of Anterior Cruciate Ligament (ACL) repair with the Ligamys® surgical technique versus standard technique. The aim of the study is to compare (laxity, instability, and safety) these two types of treatment by…
- Trial name
- LIGAMYS (NCT02740452)
- Testing
- ligamys technique, standard technique (anatomic reconstruction)
- Where
- France
- Volunteers
- 80 people
- Sponsor
- University Hospital, Clermont-Ferrand
Anterior Cruciate Ligament (ACL) Tear
Measuring Knee Laxity and Pivot Shift in ACL-Deficient Patients
The goal of this observational study is to learn whether the Robotic Knee Testing system can measure knee looseness in adults with an anterior cruciate ligament, or ACL, tear.
- Trial name
- NCT07688967
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Arthroresearch LLC
Patellar Dislocation, ACL Injury
The Faroese Knee Cohort: Etiology and Long-term Implications of Trochlear Dysplasia and Patellar Dislocations.
The investigators intend to establish a national cohort including all persons in the ages from 15-20 years old with patellar instability (PI) or a prior knee injury (ACL-ruptur or meniscus damage) .
- Conditions
- Patellar Dislocation, ACL Injury, Meniscus Lesion, Trochlear Dysplasia
- Trial name
- FKC (NCT04607538)
- Testing
- No intervention is made
- Where
- Denmark
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Hvidovre University Hospital
Rheumatoid Arthritis, Systemic Lupus Erythematosus
Prevention of Arthritis-Related Work Disability
People with rheumatic disorders (arthritis) often have trouble keeping their jobs. This study will look at whether vocational rehabilitation (VR) will improve the ability of employed people with arthritis to keep their jobs.
- Conditions
- Rheumatoid Arthritis, Systemic Lupus Erythematosus, Osteoarthritis, Knee, Ankylosing Spondylitis
- Trial name
- NCT00000416
- Testing
- Rehabilitation counseling
- Where
- United States
- Volunteers
- 242 people
- Sponsor
- Boston University Charles River Campus
Joint Instability
A Multi-Site Evaluation of the Pain Relief, Support, Fit and Comfort From Use of a Custom Knee or Ankle Brace in Persons Suffering From Chronic Ankle or Knee Pain and Instability
This study will look to examine the overall performance of a custom fit knee or ankle brace as a means of providing ankle or knee joint support in subjects that have determined the need for bracing based upon chronic joint…
- Trial name
- NCT02682654
- Testing
- Dr. Scholl's Prototype Ankle Brace, Dr. Scholl's Prototype Knee Brace
- Where
- 2 sites in United States
- Volunteers
- 183 people
- Sponsor
- Bayer
Osteoarthritis, Knee
A New Technique to Produce Anatomical Alignment Results With Less Midflexion Instability in Total Knee Arthroplasty
Beside the current standard of classical mechanical alignment of total knee replacements, increased interest is being shown in anatomical alignment.
- Trial name
- NCT02450409
- Testing
- Implantation of TKA using the gap technique, Implantation of TKA using anatomical alignment
- Where
- Germany
- Volunteers
- 56 people
- Sponsor
- University of Jena
Collateral Ligament Injury of Stifle Joint
Effectiveness of Hydrolyzed Collagen Peptide Injection for the Treatment of Collateral Ligament Pain
Conducted by Binh Luu Thi, Lan Tran Thi, and Minh Hang Hoang Thi at Thai Nguyen National Hospital, the study investigates a new approach to treating persistent collateral ligament pain, common among athletes.
- Trial name
- NCT05971004
- Testing
- Arthrys (Collagen Peptide solution), Depo medrol
- Where
- San Marino
- Volunteers
- 62 people
- Sponsor
- Tiss'You srl
Patellar Dislocation, Patellar Dislocation, Recurrent
PROMs and Patellar Tracking After MPFL Reconstruction With or Without Tibial Tuberosity Transposition
Patellar dislocations cause pain and functional decline in adolescents, which can be restored by a MPFL reconstruction with or without tibial tuberosity transposition.
- Conditions
- Patellar Dislocation, Patellar Dislocation, Recurrent, Patellofemoral Maltracking
- Trial name
- NCT05547269
- Where
- Netherlands
- Volunteers
- 11 people
- Sponsor
- Radboud University Medical Center
Rupture of the Anterior Cruciate Ligament With Instability of the Knee Joint
Evaluation of Arthroscopic Reconstruction of the Anterior Cruciate Ligament by One Night Hospital Stay or by Day Surgery: a Randomised, Prospective Clinical Trial
Patients who suffered from a rupture of the Anterior Cruciate Ligament with instability of the knee joint, will be treated with an operative ACL-reconstruction.
- Trial name
- NCT00620477
- Testing
- injection in the knee joint with 20 ml of chirocaine 0.125%, injection in the knee joint with 20 ml of physiological fluid
- Where
- Belgium
- Volunteers
- 60 people
- Sponsor
- University Hospital, Ghent
Knee Instability
Patellar Tendon Regeneration With Platelet-rich Plasma
The central third of the patellar tendon is used as a donor site for anterior cruciate ligament (ACL) reconstruction. After months or years the harvest site partially regenerates.
- Trial name
- NCT01111747
- Testing
- Platelet-rich plasma, Control group
- Volunteers
- 27 people
- Sponsor
- University of Sao Paulo General Hospital
4DCT, Knee, Femoropatellar Instability
Morphological and Biomechanical Analysis of Knee Four Dimensional CT (4DCT) in Femoropatellar Instability
To compare the radiological parameters measured by dynamic four dimensional CT (4DCT) in the analysis of patellofemoral involvement of subjects (amplitude of patellofemoral tilt angle variations, coefficient of variation of the…
- Trial name
- EDYG (NCT03535389)
- Testing
- Knee 4DCT
- Volunteers
- 40 people
- Sponsor
- Central Hospital, Nancy, France
Patellar Instability
Computational Simulation of Patellar Instability
Computational simulation will be performed to represent motion of knees with a dislocating kneecap. Common surgical treatment methods will be simulated and anatomical parameters commonly associated with the dislocation will be…
- Trial name
- NCT02998372
- Testing
- patellar stabilization
- Where
- United States
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- Cleveland Clinic Akron General
Knee Arthritis, Knee Osteoarthritis
In-vivo Wear Behaviour of AS Coated Versus Uncoated Columbus® Total Knee Prosthesis
This clinical study is a Post-Market Clinical Follow-Up (PMCF) measure and is aiming to compare the in-vivo wear behaviour of the Columbus® total knee prosthesis between the standard Cobalt Chromium (CoCr) and the multilayer…
- Conditions
- Knee Arthritis, Knee Osteoarthritis, Primary Osteoarthritis of Knee Nos, Secondary Osteoarthritis of Knee Nos
- Trial name
- COLRAS (NCT05509972)
- Testing
- total knee prosthesis implantation
- Where
- Germany
- Volunteers
- 7 people
- Sponsor
- Aesculap AG
Knee Osteoarthritis
Using Intraoperative Sensing Technology to Evaluate Revision Total Knee Arthroplasty
This study will attempt to draw relationships between the soft-tissue related complications contributing to early TKA revision and the loading and positional patterns from intraoperative tibial trial sensors.
- Trial name
- NCT03023410
- Testing
- VERASENSE
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Orthosensor, Inc.
Patella Dislocation Recurrent, Children, Only
Assessment of Knee Flexor Muscles Strength in Patients With Patellar Instability
The study enrolled 33 patients with confirmed recurrent patellar dislocation, including 6 patients with bilateral involvement. In the study group, both side hamstring muscle were evaluated at the velocities of 60 and 180 deg/s…
- Trial name
- NCT04838158
- Testing
- Isokinetic measurements
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Polish Mother Memorial Hospital Research Institute
ACL-injury
Influence of Injury to the Kaplan Fibers in Adult and Pediatric Patients With ACL Injury
The goal of this [type of study: observational study] is to [detect concomitant KF and ALL injury in knees with ACL injury using MRI in both adult and pediatric patients and compare the effect of KF injury and multiple risk…
- Trial name
- NCT06002308
- Testing
- Age
- Where
- China
- Volunteers
- 540 people
- Sponsor
- Sichuan Province Orthopetic Hospital
Chronic Ankle Instability, CAI
Assessment of Torso Musculature and Hamstring Flexibility in Patients With Chronic Ankle Instability
The purpose of this study is to assess torso musculature in terms of static and dynamic core muscle endurance tests and hamstring flexibility in non-athletic patients with unilateral chronic ankle instability.
- Trial name
- NCT06925191
- Testing
- Group A (Experimental): 29 affected ankles of both genders diagnosed with Chronic ankle instability (CAI) who met the inclusion criteria. Group B (Control): 29 matched non-affected with CAI
- Where
- Egypt
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Cairo University