Clinical trials: Knee Joint
Knee Osteoarthritis
Sanomechanics® Rehabilitative Technology
Rehabilitative Sanomechanics Method (RSM) of exercise designed to restore normal subperiosteal transmission of in-joint pressures and normalizing contact pressures on cartilages, will reduce pain in the affected joints and…
- Trial name
- NCT05512507
- Testing
- Physical Therapy Program
- Volunteers
- 15 people
- Sponsor
- PolyOrth International
Knee Osteoarthritis
Long-Term Follow-up Study of Subjects With Knee Osteoarthritis Who Had Administered FURESTEM-OA Kit Inj. in K0701 Study
Long-Term Follow-up Study of Subjects with Knee Osteoarthritis who had administered FURESTEM-OA Kit Inj. in K0701 study
- Trial name
- NCT06013306
- Volunteers
- 58 people
- Sponsor
- Kang Stem Biotech Co., Ltd.
Knee Osteoarthritis
Oxford UKA and HTO Post-market Clinical Study
The purpose of this study is to compare the performance and safety of medial UKA and HTO in the treatment of AMOA in term of functional outcome, radiographic assessment, range of motion, postoperative complications, revision rate…
- Trial name
- NCT04518111
- Where
- China
- Volunteers
- 370 people
- Sponsor
- Zimmer Biomet
Cartilage or Osteochondral Defects in the Knee
COPLA® Cartilage Implant Pilot Clinical Trial
This is a first-in-human clinical, open label, non-randomized, prospective investigation to assess the initial safety and performance of the COPLA® cartilage implant.
- Trial name
- NCT05685316
- Testing
- COPLA® cartilage implant
- Where
- 6 sites in Estonia, Finland and 1 more
- Volunteers
- 20 people
- Sponsor
- Askel Healthcare Ltd
Arthritis, Degenerative
3VM for Treatment of Chronic Osteoarthritis Knee Pain
A double-blind, placebo-controlled, randomized dose ranging study for the use of 3VM1001 Cream, 2g three times daily, 3g three times daily, or 3g four times daily for treatment of chronic pain associated with osteoarthritis of…
- Trial name
- NCT03142178
- Testing
- Experimental: 3VM1001 active 2g Cream 3 times daily, Experimental: 3VM1001 active 3g Cream 3 times daily, Experimental: 3VM1001 active 3g Cream 4 times daily
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- CDA Research Group, Inc.
Osteoarthritis of the Knee
Total Knee Arthroplasty Functional Outcomes Study Research Design
The purpose of this study is to obtain patient oriented and clinically oriented physical function outcomes both pre-operatively and post-operatively in patients receiving a total knee arthroplasty.
- Trial name
- NCT02228538
- Testing
- Total knee arthroplasty patients
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Restor3D
Knee Osteoarthritis
Comparative Usability Evaluation of Sustained Acoustic Medicine (SAM) Devices and Topical Gel for OA Knee Pain
The purpose of this study is to evaluate the usability of the ultrasound devices and common pain relief gel. The ability of the three treatment approaches to reduce pain, stiffness, and functionality as measured by NRS scale and…
- Trial name
- NCT05050448
- Testing
- Sustained Acoustic Device with 2.5% Diclofenac Patch, 1% Diclofenac Topical Gel
- Where
- 3 sites in United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- ZetrOZ, Inc.
Joint Disease
Post Market Follow-Up Study of the EVOLUTION® Total Knee Arthroplasty System With Cruciate Sacrificing Inserts
MPO is conducting this PMCF study to evaluate the safety and efficacy of its EVOLUTION® Total Knee Arthroplasty (TKA) components marketed in the EU.
- Trial name
- AMETHYST (NCT02351414)
- Testing
- Total Knee Arthroplasty (EVOLUTION®)
- Where
- 5 sites in United States, Belgium and 3 more
- Volunteers
- 150 people
- Sponsor
- MicroPort Orthopedics Inc.
Knee Osteoarthritis
Safety of Single Doses of SAR113945 and Efficacy and Safety of a New Formulation Given Into the Knee in Osteoarthritis Patients / Part II
Study objectives: Part 1 TDU11685 To assess in patients with knee Osteoarthritis (OA), the safety, tolerability and pharmacokinetics (PK) of single intra-articular doses of SAR113945.
- Trial name
- NCT01598415
- Testing
- SAR113945
- Where
- 2 sites in Germany
- Volunteers
- 130 people
- Sponsor
- Sanofi
Osteoarthritis
Sigma CR150 Versus Sigma CR Knee RCT
This study will compare two very similar designs of knee replacement device. One device (Sigma CR150) is a slightly modified version of the original (Sigma CR) and has been modified to enhance/accommodate higher flexion.
- Trial name
- NCT01418378
- Testing
- Sigma CR150, Sigma CR
- Where
- 4 sites in India, Singapore and 1 more
- Volunteers
- 191 people
- Sponsor
- DePuy International
Joint Infection
Study in Patients Undergoing Debridement, Antibiotics, and Implant Retention (DAIR) for Treatment of a Periprosthetic Joint Infection (PJI) Occurring After Total Knee Arthroplasty (TKA)
The purpose of this study is to learn about the safety and effects of PLG0206 for treating periprosthetic joint infections (PJI) in conjunction with the DAIR (debridement, antibiotics and implant retention) surgical procedure for…
- Trial name
- NCT05137314
- Testing
- PLG0206
- Where
- 12 sites in United States
- Volunteers
- 14 people
- Sponsor
- Peptilogics
Osteoarthritis of the Knee
Evaluation of Amniotic Fluid Product in Knee Osteoarthritis
A study evaluating Amniotic Fluid compared to a Saline Placebo Injection in the treatment of subjects with osteoarthritic (OA) knee pain
- Trial name
- NCT02768155
- Testing
- Amniotic Fluid 4.0ml dose, Amniotic Fluid 2.0ml dose
- Where
- 2 sites in United States
- Volunteers
- 60 people
- Sponsor
- MiMedx Group, Inc.
Osteoarthritis of the Knee, Total Knee Replacement
Prophecy Guide Outcomes in Total Knee Replacement Surgery
This project aims to assess two different techniques used to position the knee replacement implant during surgery. The patients will be randomised to receive either the following: 1.
- Trial name
- NCT01163708
- Testing
- Prophecy Technique, Navigation System
- Where
- 2 sites in Australia
- Volunteers
- 188 people
- Sponsor
- Global Orthopaedic Technology
Surgical Adhesions
JOCOAT Safety and Tolerability Clinical Trial GLAD-04
This study will assess the safety and efficacy of a new liquid anti-adhesion device, JOCOAT(TM) APN-3003 in patients undergoing knee anterior cruciate ligament reconstruction (ACLR) surgery.
- Trial name
- NCT07081815
- Testing
- JOCOAT(TM) APN-3003
- Volunteers
- 24 people
- Sponsor
- ARC Medical Inc.
Osteoarthritis, Knee
PFC Sigma Fixed and Mobile Knee Study
The primary objective of this investigation is to evaluate the performance (in terms of post-operative active range of motion at one year) of the P.F.C. Sigma and P.F.C.
- Trial name
- NCT00208325
- Testing
- P.F.C Sigma Fixed Bearing total knee system, P.F.C Sigma RP Mobile Bearing knee system
- Where
- 4 sites in United Kingdom
- Volunteers
- 754 people
- Sponsor
- DePuy International
Osteoarthritis, Knee
Efficacy and Safety of Intraarticular Sodium Hyaluronate Single Injection in Patients With Osteoarthritis of the Knee
A Phase III, prospective, multicentre, non-controlled, with consecutive participant enrollment in order to evaluate the efficacy, safety and duration of the effects of the viscosupplementation with a preparation of sodium…
- Trial name
- NCT03852914
- Testing
- Sodium hyaluronate 2%
- Where
- 10 sites in Spain
- Volunteers
- 93 people
- Sponsor
- Tedec-Meiji Farma, S.A.
Knee Injuries and Disorders
AIR (Artificial Implant to Restore the Medial Meniscus Function)2 Clinical Investigation
The AIR2 Study is a multi-center, prospective, interventional clinical trial with the objective to evaluate the safety and performance of the Trammpolin® medial meniscus prosthesis.
- Trial name
- AIR2 (NCT05297175)
- Testing
- Trammpolin medial meniscus prosthesis
- Where
- 3 sites in Netherlands
- Volunteers
- 10 people
- Sponsor
- ATRO Medical B.V.
the Treatment of Knee Osteoarthritis
Intra-articular Administration of Med Device Made of Biological Vegetal Matrix for the Treatment of Knee Osteoarthritis
A pre-market randomized, parallel group, single-blind, clinical study with a Medical Device, made of vegetal material, to evaluate the efficacy and safety of one knee injection of the investigational device versus active…
- Trial name
- NCT05925595
- Testing
- Medical Device Iniettabile Ginocchio
- Where
- Italy
- Volunteers
- 150 people
- Sponsor
- Bios-Therapy, Physiological Systems for Health S.p.A
Knee Osteoarthritis
Combination of PRP and XLHA Prepared With RegenMatrix Medical Device To Treat Moderate to Severe Knee Osteoarthritis
In this clinical trial the investigator assess the safety and efficacy of a single injection of a combination of cross-linked hyaluronic acid (HA) with autologous platelet-rich plasma (PRP) obtained with the RegenMatrix medical…
- Trial name
- NCT05727371
- Testing
- Regen Matrix-PRP-XLHA, Hylan G-F 20
- Where
- 13 sites in France
- Volunteers
- 280 people
- Sponsor
- RegenLab France SAS
Cartilage Injury, Defect of Articular Cartilage
BioPoly RS Knee Registry Study for Cartilage Defect Replacement
Information will be collected on the pre-op and post-op clinical status of patients with focal cartilage defects of the femoral condyles treated with the BioPoly RS Partial Resurfacing Knee Implant, a permanent orthopaedic…
- Conditions
- Cartilage Injury, Defect of Articular Cartilage, Cartilage Damage
- Trial name
- NCT01473199
- Testing
- BioPoly RS Partial Resurfacing Knee Implant
- Where
- 5 sites in United Kingdom
- Volunteers
- 38 people
- Sponsor
- BioPoly LLC
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.